IMB Centre for Inflammation and Disease Research

Researchers have solved the structure of a complex molecular machine responsible for sorting and transporting cellular cargo.

A University of Queensland research discovery reveals how the body puts the brakes on inflammation, a discovery that will help us understand how poorly controlled inflammation exacerbates diseases including cystic fibrosis, Alzheimer’s, atherosclerosis and cancer.

For the first time, scientists have seen in exquisite, real-time detail how immune cells survey their surroundings to detect threats to our health.

Associate Professor Kate Schroder and her team uncovered a new line of defence deployed by the immune system against bacteria.

Researchers have revealed how immune cells are prompted to release the protein interleukin-1beta, in a discovery that gives new insight into how our immune systems drives diseases such as auto-inflammatory diseases, arthritis and gout.

University of Queensland scientists have identified genes associated with fatty liver disease, a condition affecting 5.5 million Australians.

Research into sepsis, a devastating disease that is particularly dangerous for children and the elderly, has caught the imagination of Queenslanders, with a PhD student from The University of Queensland winning the 2018 Women in STEM Prize People’s Choice Award.

Sepsis occurs when the body’s immune response to infection damages its own tissues. In severe cases, multiple organ failure can occur. If not treated promptly, the patient will die. Yet, we currently don't have reliable treatments for it. Our solution is to target the immune system itself. My PhD focuses on a machine in our cells that is important for recognising bacterial infection and recruiting immune responders. My goal is to discover how we can switch this machine on and off.