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- Dr Alysha Elliott is discovering new ways of tackling anti-microbial resistance.
Adjunct and Honorary
Ms Kylie Ahern
Industry FellowResearcher profile is public:0Supervisor:Mr Robert Christiansen
Adjunct ProfessorInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Adjunct Professor Michael Holmes
Adjunct ProfessorInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:Adjunct Professor Norelle Daly
Adjunct ProfessorInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:Honorary Professor Michael Goddard
Honorary ProfessorInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:Professor Wanjin Hong
Honorary ProfessorInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:Honorary Professor Melissa Little
Honorary ProfessorInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:Emerita Professor Jenny Martin
Emerita ProfessorInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Researcher biography:Jenny Martin trained as a pharmacist at the Victorian College of Pharmacy (VCP), where she was awarded the Gold Medal for top student over the BPharm course. After completing an MPharm in computational chemistry at the College, Jenny moved to Oxford University for a PhD by research in protein crystallography and drug design. Her DPhil was supported by a prestigious 1851 Science Research Scholarship and several other competitive scholarships. Jenny then undertook two years of postdoctoral research at Rockefeller University in New York, before returning to Australia in 1993 to establish the first protein crystallography laboratory in Queensland. Since then, she has held ARC QEII, ARC Professorial and NHMRC Fellowships and is currently an ARC Australian Laureate Fellow at the Institute for Molecular Bioscience, University of Queensland. Jenny is the recipient of many honours including the ASBMB Roche Medal, the Queensland Smart Women Smart State Research Scientist award, and the Women in Biotech Outstanding Outstanding Biotechnology Achievement Award.
Honorary Professor John Mattick
Honorary ProfessorInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:Honorary Professor Luke O'Neill
Honorary ProfessorInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:Honorary Professor Vicki Sara
Institute for Molecular BioscienceResearcher profile is public:0Supervisor:Body:Professor Vicki Sara was elected Chancellor of the University of Technology Sydney in 2004. Professor Sara is a Fellow of the Australian Academy of Science and the Australian Academy of Technological Sciences and Engineering.
Professor Sara’s previous appointments include Chief Executive Officer of the Australian Research Council from 2001-2004 and Chair of the Council and a member of the Prime Minister’s Science Engineering and Innovation Council (PMSEIC), and the CSIRO Board from 1997-2001. Professor Sara was also a member of the Advisory Board of the Rio Tinto Foundation for a Sustainable Minerals Industry from 2002-2007, Consul General for Sweden in Sydney from 2006-2007, andwas appointed Vice-Chair of the OECD’s Global Science Forum in 1999 and member of the Advisory Board of the APEC R&D Leaders’ Forum in 2002. She was Director of the Australian Centre for Plant Functional Genomics from 2004-2009, the Australian Institute of Commercialisation 2007- 2010, Chair of the Board of the Australian Stem Cell Centre from 2005-2008, Chair of the Advisory Board of the Centre for Quantum Computation and Communication Technology 2011-2012, and Chair NSW Panel Sir John Monash Scholarship 2011-2013. Professor Sara was elected Convenor of the University Chancellors Council 2006-2008 and 2011-2012.
Professor Sara returned to Australia in 1993 following a research career at the Karolinska Institute in Stockholm.
She was awarded the Rolf Luft medal in 1993 for excellence in endocrine research by the Karolinska Institute, and also received the Sir John Eccles Award from the NH&MRC in 1994. She was appointed as foreign Professor of Karolinska Institute in 1995. She was awarded the Centenary Medal in 2003, and was awarded an Honorary Doctor of Science by the University of Southern Queensland in 2004, the Victoria University in 2005, the University of Technology Sydney in 2009, and the University of Sydney in 2016. She was awarded an Honorary Doctor of the University, Queensland University of Technology in 2006.
Professor Sara was appointed an Officer of the Order of Australia (AO) for distinguished service to science and higher education in 2010
Honorary Professor Ben Hogan
Honorary ProfessorInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:- Global Challenges ScholarInstitute for Molecular Bioscience
- Visiting ScholarInstitute for Molecular Bioscience
- PhD StudentInstitute for Molecular Bioscience
Wainwright Group
Group Leader
Professor Brandon Wainwright
Group Leader, Genomics of Development and Disease DivisionAffiliate Professor of Institute for Molecular BioscienceInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Researcher biography:Professor Brandon Wainwright AM is Co-Director of the Children’s Brain Cancer Centre and leads a laboratory within the UQ Diamantina Institute focused on understanding the genetic pathways behind medulloblastoma, a type of brain tumour that occurs predominantly in children. He is Chair of the European Molecular Biology Laboratory (EMBL) Australia, Chair of the Advisory Board of the Robinson Research Institute and Chair of the Board of the South Australian Immunogenomics Cancer Institute (SAIGENCI), and serves on the boards the Australian Genome Research Facility as well as several national and international scientific review committees, including the MRFF Brain Tumour Roadmap Committee.
Professor Wainwright completed his undergraduate and postgraduate studies at The University of Adelaide, after which he secured a postdoctoral fellowship with St Mary's Hospital at Imperial College London. During his six years at Imperial he worked on the first human genome project and also became a Medical Research Council Senior Research Fellow. He returned to Australia in 1990 to join UQ's Centre for Molecular and Cellular Biology (now IMB) and led the Institute for Molecular Biology until 2019.
Professor Wainwright is a geneticist, renowned for discovering the genetic pathway that causes most human cancer. He is skilled in molecular genetics, where he is using genetic approaches to dig through DNA and find the genes that cause disease. He commenced using these skills to locate the cystic fibrosis gene, but it was when isolating a gene responsible for a rare form of brain cancer called Medulloblastoma, that he discovered the role of the ‘Hedgehog Pathway' in common human cancer.
Body:Highlights
Professor Brandon Wainwright AM is a geneticist, renowned for discovering the genetic pathway that causes most human cancer. He is skilled in molecular genetics, where he is using genetic approaches to dig through DNA and find the genes that cause disease.
He commenced using these skills to locate the cystic fibrosis gene, but it was when isolating a gene responsible for a rare form of brain cancer called Medulloblastoma, that he discovered the ‘Hedgehog Pathway.'
He discovered not only the first brain cancer-causing gene but also a pathway involved in most cancers of all types.
The primary focus of his current research is brain cancer because it is the most common cause of death in children and the most common cause of cancer-related death in people under 40. He is also applying his expertise to common cancer generally (particularly skin cancer), and neurodegenerative disease.
Success for Professor Wainwright will be seeing a child cured of brain cancer that would otherwise have died. And he is confident that he can help make it happen.
He is formerly Director of UQ's Institute for Molecular Bioscience, where he proudly leads a team of talented discovery scientists translating their findings to life-changing applications.
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Researchers
Dr Laura Genovesi
Honorary Senior Research FellowInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Researcher biography:Laura Genovesi is a Cure Brain Cancer Foundation Research Fellow within the Paediatric Brain Cancer Laboratory headed by Professor Brandon Wainwright.
Dr Genovesi is a cancer biologist specialising in in vivo pre-clinical models to dissect the mechanisms underpinning growth of medulloblastoma, a paediatric brain tumour. They were awarded their PhD in 2012 (University of Western Australia), where they studied the role of microRNAs in the transformation of human neural stem cells to Medulloblastoma. They relocated to the University of Queensland to commence her post-doctoral studies in the laboratory of Prof. Brandon Wainwright. Dr Genovesi's post-doctoral research focuses on discovering and targeting the genetic networks that drive medulloblastoma. Their work has contributed to defining regulatory networks underlying the growth of medulloblastoma and the therapeutic application of CDK4/6 inhibitors in the treatment of medulloblastoma. Most recently, her work has characterised the status of the blood brain barrier in some of the most widely used patient derived orthotopic xenograft models of medulloblastoma. Dr Laura Genovesi's research is now focused on understanding the intrinsic and adaptive plasticity of tumour cells and acellular components of the brain tumour microenvironment (TME) that drive tumour progression and determine response to therapy. Their research integrates integrates diverse preclinical model systems including patient-derived in vivo models and dynamic ex vivo 3D hydrogel models with innovative spatial transcriptomics/ imaging and advanced computational cancer biology aiming to ultimately to improve the lives of children diagnosed with brain tumours.
Students
Dr Pengxiang Ji
Higher degree by research (PhD) studentInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:Mr James Fraser
Higher degree by research (PhD) studentInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:- Adjunct Associate ProfessorInstitute for Molecular Bioscience
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Strawberry DNA extraction activity
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The Edge: Genetics
People have known for thousands of years that parents pass traits to their children, but it is only relatively recently that our technology has caught up to our curiosity, enabling us to delve into the mystery of how this inheritance occurs, and the implications for predicting, preventing and treating disease.
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