Honorary Professor Melissa Little

Hale, Lorna J. and Little, Melissa H. (2023). Generating human glomeruli from pluripotent stem cells for disease modelling and drug screening. Kidney research experimental protocols. (pp. 55-68) edited by Tim D. Hewitson, Nigel D. Toussaint and Edward R. Smith. New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-3179-9_5

Howden, Sara E. and Little, Melissa H. (2020). Generating Kidney Organoids from Human Pluripotent Stem Cells Using Defined Conditions. Stem Cells and Tissue Repair: Methods and Protocols. (pp. 183-192) edited by Kioussi, C. New York, NY United States: Humana Press. doi: 10.1007/978-1-0716-0655-1_15

Little, Melissa H., Takasato, Minoru, Soo, Joanne Y.-C. and Forbes, Thomas A. (2017). Recapitulating development to generate kidney organoid cultures. Organ Regeneration Based on Developmental Biology. (pp. 193-222) Singapore: Springer. doi: 10.1007/978-981-10-3768-9_11

Combes, Alexander N., Davies, Jamie A. and Little, Melissa H. (2015). Cell-Cell Interactions Driving Kidney Morphogenesis. Cellular Adhesion in Development and Disease. (pp. 467-508) edited by Alpha S. Yap. Maryland Heights, MO United States: Academic Press. doi: 10.1016/bs.ctdb.2014.12.002

Little, Melissa H. (2015). Reprogramming to Kidney. Kidney Development, Disease, Repair and Regeneration. (pp. 447-461) Elsevier Science Ltd.. doi: 10.1016/B978-0-12-800102-8.00033-3

Davies, Jamie A., Unbekandt, Mathieu, Ineson, Jessica, Lusis, Michael and Little, Melissa H. (2012). Dissociation of embryonic kidney followed by re-aggregation as a method for chimeric analysis. Kidney development: methods and protocols. (pp. 135-146) edited by Odysse Michos. New York , NY, United States: Humana Press. doi: 10.1007/978-1-61779-851-1_12

Rumballe, Bree A., Chiu, Han Sheng, Georgas, Kylie M. and Little, Melissa H. (2012). Use of in situ hybridization to examine gene expression in the embryonic, neonatal, and adult urogenital system. Kidney development: Methods and protocols. (pp. 223-239) edited by Odysse Michos. New York , NY, United States: Humana Press. doi: 10.1007/978-1-61779-851-1_20

Davies, Jamie A., Little, Melissa H., Aronow, Bruce, Armstrong, Jane, Brennan, Jane, Lloyd-Macgilp, Sue, Armit, Chris, Harding, Simon, Piu, Xinjun, Roochun, Yogmatee, Haggarty, Bernard, Houghton, Derek, Davidson, Duncan and Baldock, Richard (2012). Access and use of the GUDMAP database of genitourinary development. Kidney development: methods and protocols. (pp. 185-201) edited by Odysse Michos. New York, NY, United States: Humana Press. doi: 10.1007/978-1-61779-851-1_17

Little, M. H. and Challen, G. A. (2011). Potential of the Side Population in Regenerative Nephrology. Regenerative Nephrology. (pp. 173-188) edited by Michael S Goligorsky. Amsterdam, The Netherlands: Elsevier Inc.. doi: 10.1016/B978-0-12-380928-5.10011-9

Little, M. H. (2005). Wilms' Tumor: Starting off the kidney all over again. Developmental Biology of Neoplastic Growth. (pp. 107-132) edited by Alvero Macieira-Coelho. Berlin, Heidelberg: Springer-Verlag.

Dorison, Aude, Santos, Inês Paz, Ghobrial, Irene, Lam, Rachel, Stuber, Katrin, Danne, Jillian Clare, See, Michael M., Ramm, Georg, Rossello, Fernando Jaime, Ramialison, Mirana, Emdal, Kristina B. and Little, Melissa H. (2024). Endosomal Recycling and Proteasomal Degradation of R168H Variant Podocin Contributes to Nephrotic Syndrome Pathophysiology : FR-PO761. Journal of the American Society of Nephrology, 35 (10S). doi: 10.1681/asn.20243by4g38b

Vanslambrouck, Jessica May, Tan, Ker sin, Mah, Sophia Ying Yii, Dominic, Kathleen and Little, Melissa H. (2024). Controlling Proximal Nephron Arrangement and Maturity in Stem Cell-Derived Engineered Kidney Tissue : TH-PO398. Journal of the American Society of Nephrology, 35 (10S). doi: 10.1681/asn.2024484msscg

Vanslambrouck, Jessica M., Neil, Jessica A., Rudraraju, Rajeev, Mah, Sophia, Tan, Ker Sin, Groenewegen, Ella, Forbes, Thomas A., Karavendzas, Katerina, Elliott, David A., Porrello, Enzo R., Subbarao, Kanta and Little, Melissa H. (2024). Kidney organoids reveal redundancy in viral entry pathways during ACE2-dependent SARS-CoV-2 infection. Journal of Virology, 98 (3), e0180223. doi: 10.1128/jvi.01802-23

Vanslambrouck, Jessica M., Tan, Ker Sin, Mah, Sophia and Little, Melissa H. (2023). Generation of proximal tubule-enhanced kidney organoids from human pluripotent stem cells. Nature Protocols, 18 (11), 3229-3252. doi: 10.1038/s41596-023-00880-1

Jensen, Kim Bak and Little, Melissa Helen (2023). Organoids are not organs: sources of variation and misinformation in organoid biology. Stem Cell Reports, 18 (6), 1255-1270. doi: 10.1016/j.stemcr.2023.05.009

Little, Melissa H. and Rabelink, Ton J. (2023). Replacing renal function using bioengineered tissues. Nature Reviews Bioengineering, 1 (8), 576-588. doi: 10.1038/s44222-023-00066-0

Dorison, Aude, Ghobrial, Irene, Graham, Alison, Peiris, Thanushi, Forbes, Thomas A., See, Michael, Das, Mithun, Saleem, Moin A., Quinlan, Catherine, Lawlor, Kynan T., Ramialison, Mirana, Howden, Sara E. and Little, Melissa H. (2023). Kidney organoids generated using an allelic series of NPHS2 point variants reveal distinct intracellular podocin mistrafficking. Journal of the American Society of Nephrology : JASN, 34 (1), 88-109. doi: 10.1681/ASN.2022060707

Dorison, Aude, Forbes, Thomas A. and Little, Melissa H. (2022). What can we learn from kidney organoids?. Kidney International, 102 (5), 1013-1029. doi: 10.1016/j.kint.2022.06.032

Vanslambrouck, Jessica M., Wilson, Sean B., Tan, Ker Sin, Groenewegen, Ella, Rudraraju, Rajeev, Neil, Jessica, Lawlor, Kynan T., Mah, Sophia, Scurr, Michelle, Howden, Sara E., Subbarao, Kanta and Little, Melissa H. (2022). Enhanced metanephric specification to functional proximal tubule enables toxicity screening and infectious disease modelling in kidney organoids. Nature Communications, 13 (1) 5943, 1-23. doi: 10.1038/s41467-022-33623-z

Ke, Francine S., Holloway, Steven, Uren, Rachel T., Wong, Agnes W., Little, Melissa H., Kluck, Ruth M., Voss, Anne K. and Strasser, Andreas (2022). The BCL‐2 family member BID plays a role during embryonic development in addition to its BH3‐only protein function by acting in parallel to BAX, BAK and BOK. The EMBO Journal, 41 (15) e110300, 1-18. doi: 10.15252/embj.2021110300

Little, Melissa, Morrison, Sean J., Rossant, Janet, Srivastava, Deepak and Daley, George Q. (2022). Anniversary reflections: ISSCR presidents on 20 years of progress. Cell Stem Cell, 29 (6), 876-878. doi: 10.1016/j.stem.2022.05.003

Wilson, Sean B., Howden, Sara E., Vanslambrouck, Jessica M., Dorison, Aude, Alquicira-Hernandez, Jose, Powell, Joseph E. and Little, Melissa H. (2022). DevKidCC allows for robust classification and direct comparisons of kidney organoid datasets. Genome Medicine, 14 (1) 19, 19. doi: 10.1186/s13073-022-01023-z

Little, Melissa H. and Howden, Sara E. (2022). Forward steps in organoid-based forward screening. Cell Stem Cell, 29 (1), 7-8. doi: 10.1016/j.stem.2021.12.004

Cook, Blake, Combes, Alex, Little, Melissa and Osborne, James M. (2022). Modelling cellular interactions and dynamics during kidney morphogenesis. Bulletin of Mathematical Biology, 84 (1) 8. doi: 10.1007/s11538-021-00968-3

Little, Melissa H. and Humphreys, Benjamin D. (2022). Regrow or repair: an update on potential regenerative therapies for the kidney. Journal of the American Society of Nephrology, 33 (1), 15-32. doi: 10.1681/asn.2021081073

Shen, Sophie, Sun, Yuliangzi, Matsumoto, Maika, Shim, Woo Jun, Sinniah, Enakshi, Wilson, Sean B., Werner, Tessa, Wu, Zhixuan, Bradford, Stephen T., Hudson, James, Little, Melissa H., Powell, Joseph, Nguyen, Quan and Palpant, Nathan J. (2021). Integrating single-cell genomics pipelines to discover mechanisms of stem cell differentiation. Trends in Molecular Medicine, 27 (12), 1135-1158. doi: 10.1016/j.molmed.2021.09.006

Little, Melissa H., Howden, Sara E., Lawlor, Kynan T. and Vanslambrouck, Jessica M. (2021). Determining lineage relationships in kidney development and disease. Nature Reviews Nephrology, 18 (1), 8-21. doi: 10.1038/s41581-021-00485-5

Wilson, Sean B. and Little, Melissa H. (2021). The origin and role of the renal stroma. Development, 148 (19) dev199886. doi: 10.1242/dev.199886

Djenoune, Lydia, Tomar, Ritu, Dorison, Aude, Ghobrial, Irene, Schenk, Heiko, Hegermann, Jan, Beverly-Staggs, Lynne, Hidalgo-Gonzalez, Alejandro, Little, Melissa H. and Drummond, Iain A. (2021). Autonomous calcium signaling in human and zebrafish podocytes controls kidney filtration barrier morphogenesis. Journal of the American Society of Nephrology, 32 (7), 1697-1712. doi: 10.1681/ASN.2020101525

Little, Melissa H. (2021). Returning to kidney development to deliver synthetic kidneys. Developmental Biology, 474, 22-36. doi: 10.1016/j.ydbio.2020.12.009

Howden, Sara E., Wilson, Sean B., Groenewegen, Ella, Starks, Lakshi, Forbes, Thomas A., Tan, Ker Sin, Vanslambrouck, Jessica M., Holloway, Emily M., Chen, Yi-Hsien, Jain, Sanjay, Spence, Jason R. and Little, Melissa H. (2021). Plasticity of distal nephron epithelia from human kidney organoids enables the induction of ureteric tip and stalk. Cell Stem Cell, 28 (4), 671-684.e6. doi: 10.1016/j.stem.2020.12.001

Mummery, Christine, Little, Melissa, Lin, Haifan, Clark, Amander, Zaret, Ken, Barker, Roger, Bronner, Marianne, Doetsch, Fiona, Greco, Valentina, Hochedlinger, Konrad, Knoblich, Juergen, Kriegstein, Arnold, Lebkowski, Jane, Lendahl, Urban, Melton, Doug, Murry, Chuck, Pera, Martin, Pereira, Lygia, Schoeler, Hans, Takanori, Takebe, Wysocka, Joanna, Zon, Leonard, Srivastava, Deepak, Fuchs, Elaine, Watt, Fiona, Temple, Sally and ISSCR Board 2020–2021 (2021). Mentorship in Science: Response to AlShebli et al., Nature Communications 2020. Stem Cell Reports, 16 (1), 1-2. doi: 10.1016/j.stemcr.2020.12.016

Majmundar, Amar J., Buerger, Florian, Forbes, Thomas A., Klämbt, Verena, Schneider, Ronen, Deutsch, Konstantin, Kitzler, Thomas M., Howden, Sara E., Scurr, Michelle, Tan, Ker Sin, Krzeminski, Mickaël, Widmeier, Eugen, Braun, Daniela A., Lai, Ethan, Ullah, Ihsan, Amar, Ali, Kolb, Amy, Eddy, Kaitlyn, Chen, Chin Heng, Salmanullah, Daanya, Dai, Rufeng, Nakayama, Makiko, Ottlewski, Isabel, Kolvenbach, Caroline M., Onuchic-Whitford, Ana C., Mao, Youying, Mann, Nina, Nabhan, Marwa M., Rosen, Seymour ... Hildebrandt, Friedhelm (2021). Recessive NOS1AP variants impair actin remodeling and cause glomerulopathy in humans and mice. Science Advances, 7 (1) ARTN eabe1386. doi: 10.1126/sciadv.abe1386

Knarston, Ingrid M., Pachernegg, Svenja, Robevska, Gorjana, Ghobrial, Irene, Er, Pei Xuan, Georges, Elizabeth, Takasato, Minoru, Combes, Alexander N., Jørgensen, Anne, Little, Melissa H., Sinclair, Andrew H. and Ayers, Katie L. (2020). An In Vitro Differentiation Protocol for Human Embryonic Bipotential Gonad and Testis Cell Development. Stem Cell Reports, 15 (6), 1377-1391. doi: 10.1016/j.stemcr.2020.10.009

Lawlor, Kynan T., Vanslambrouck, Jessica M., Higgins, J. William, Chambon, Alison, Bishard, Kristina, Arndt, Derek, Er, Pei Xuan, Wilson, Sean B., Howden, Sara E., Tan, Ker Sin, Li, Fanyi, Hale, Lorna J., Shepherd, Benjamin, Pentoney, Stephen, Presnell, Sharon C., Chen, Alice E. and Little, Melissa H. (2020). Cellular extrusion bioprinting improves kidney organoid reproducibility and conformation. Nature Materials, 20 (2), 260-271. doi: 10.1038/s41563-020-00853-9

Little, Melissa H. (2020). Patterning a ureter is all in the stroma. Journal of the American Society of Nephrology, 31 (10), 2231-2232. doi: 10.1681/ASN.2020071055

Yermalovich, Alena V., Osborne, Jihan K., Sousa, Patricia, Han, Areum, Kinney, Melissa A., Chen, Michael J., Robinton, Daisy A., Montie, Helen, Pearson, Dan S., Wilson, Sean B., Combes, Alexander N., Little, Melissa H. and Daley, George Q. (2020). Author Correction: Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis. Nature Communications, 11 (1) 1327, 1327. doi: 10.1038/s41467-020-14944-3

Glass, Nick R., Takasako, Minoru, Er, Pei Xuan, Titmarsh, Drew M., Hidalgo, Alejandro, Wolvetang, Ernst J., Little, Melissa H. and Cooper-White, Justin J. (2020). Multivariate patterning of human pluripotent cells under perfusion reveals critical roles of induced paracrine factors in kidney organoid development. Science Advances, 6 (2) eaaw2746, 1-13. doi: 10.1126/sciadv.aaw2746

Little, Melissa H. and Lawlor, Kynan T. (2019). Recreating, expanding and using nephron progenitor populations. Nature Reviews Nephrology, 16 (2), 75-76. doi: 10.1038/s41581-019-0238-0

Little, Melissa H. (2019). Diving deep into the adult mouse kidney. Developmental Cell, 51 (3), 293-294. doi: 10.1016/j.devcel.2019.10.015

Vanslambrouck, Jessica M., Wilson, Sean B., Tan, Ker Sin, Soo, Joanne Y.-C., Scurr, Michelle, Spijker, H. Siebe, Starks, Lakshi T., Neilson, Amber, Cui, Xiaoxia, Jain, Sanjay, Little, Melissa Helen and Howden, Sara E. (2019). A toolbox to characterize human induced pluripotent stem cell-derived kidney cell types and organoids. Journal of the American Society of Nephrology, 30 (10), 1811-1823. doi: 10.1681/ASN.2019030303

Little, Melissa H. and Combes, Alexander N. (2019). Kidney organoids: Accurate models or fortunate accidents. Genes and Development, 33 (19-20), 1319-1345. doi: 10.1101/gad.329573.119

Combes, Alexander N., Phipson, Belinda, Lawlor, Kynan T., Dorison, Aude, Patrick, Ralph, Zappia, Luke, Harvey, Richard P., Oshlack, Alicia and Little, Melissa H. (2019). Single cell analysis of the developing mouse kidney provides deeper insight into marker gene expression and ligand-receptor crosstalk. Development, 146 (12) dev178673, dev178673. doi: 10.1242/dev.178673

Little, Melissa H. and Quinlan, Catherine (2019). Advances in our understanding of genetic kidney disease using kidney organoids. Pediatric Nephrology, 35 (6), 915-926. doi: 10.1007/s00467-019-04259-x

Leuning, Daniëlle G., Witjas, Franca M. R., Maanaoui, Mehdi, de Graaf, Annemarie M. A., Lievers, Ellen, Geuens, Thomas, Avramut, Christina M., Wiersma, Loes E., van den Berg, Cathelijne W., Sol, Wendy M. P. J., de Boer, Hetty, Wang, Gangqi, LaPointe, Vanessa L. S., van der Vlag, Johan, van Kooten, Cees, van den Berg, Bernard M., Little, Melissa H., Engelse, Marten A. and Rabelink, Ton J. (2019). Vascular bioengineering of scaffolds derived from human discarded transplant kidneys using human pluripotent stem cell–derived endothelium. American Journal of Transplantation, 19 (5), 1328-1343. doi: 10.1111/ajt.15200

Howden, Sara E., Vanslambrouck, Jessica M., Wilson, Sean B., Tan, Ker Sin and Little, Melissa H. (2019). Reporter‐based fate mapping in human kidney organoids confirms nephron lineage relationships and reveals synchronous nephron formation. EMBO reports, 20 (4) e47483, e47483. doi: 10.15252/embr.201847483

Kumar, Santhosh V., Er, Pei X., Lawlor, Kynan T., Motazedian, Ali, Scurr, Michelle, Ghobrial, Irene, Combes, Alexander N., Zappia, Luke, Oshlack, Alicia, Stanley, Edouard G. and Little, Melissa H. (2019). Kidney micro-organoids in suspension culture as a scalable source of human pluripotent stem cell-derived kidney cells. Development, 146 (5) dev172361, dev172361. doi: 10.1242/dev.172361

Lawlor, Kynan T, Zappia, Luke, Lefevre, James, Park, Joo-Seop, Hamilton, Nicholas A, Oshlack, Alicia, Little, Melissa H and Combes, Alexander N (2019). Nephron progenitor commitment is a stochastic process influenced by cell migration. eLife, 8 e41156. doi: 10.7554/elife.41156

Combes, Alexander N., Zappia, Luke, Er, Pei Xuan, Oshlack, Alicia and Little, Melissa H. (2019). Single-cell analysis reveals congruence between kidney organoids and human fetal kidney. Genome Medicine, 11 (1) 3, 3. doi: 10.1186/s13073-019-0615-0

Yermalovich, Alena V., Osborne, Jihan K., Sousa, Patricia, Han, Areum, Kinney, Melissa A., Chen, Michael J., Robinton, Daisy A., Montie, Helen, Pearson, Dan S., Wilson, Sean B., Combes, Alexander N., Little, Melissa H. and Daley, George Q. (2019). Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis. Nature Communications, 10 (1) 168, 168. doi: 10.1038/s41467-018-08127-4

Wanner, Nicola, Vornweg, Julia, Combes, Alexander, Wilson, Sean, Plappert, Julia, Rafflenbeul, Gesa, Puelles, Victor G., Rahman, Raza-Ur, Liwinski, Timur, Lindner, Saskia, Grahammer, Florian, Kretz, Oliver, Wlodek, Mary E., Romano, Tania, Moritz, Karen M., Boerries, Melanie, Busch, Hauke, Bonn, Stefan, Little, Melissa H., Bechtel-Walz, Wibke and Huber, Tobias B. (2019). DNA methyltransferase 1 controls nephron progenitor cell renewal and differentiation. Journal of the American Society of Nephrology: JASN, 30 (1), 63-78. doi: 10.1681/ASN.2018070736

Vanslambrouck, Jessica M., Woodard, Lauren E., Suhaimi, Norseha, Williams, Felisha M., Howden, Sara E., Wilson, Sean B., Lonsdale, Andrew, Er, Pei X., Li, Joan, Maksimovic, Jovana, Oshlack, Alicia, Wilson, Matthew H. and Little, Melissa H. (2019). Direct reprogramming to human nephron progenitor-like cells using inducible piggyBac transposon expression of SNAI2-EYA1-SIX1. Kidney International, 95 (5), 1153-1166. doi: 10.1016/j.kint.2018.11.041

Phipson, Belinda, Er, Pei X., Combes, Alexander N., Forbes, Thomas A., Howden, Sara E., Zappia, Luke, Yen, Hsan-Jan, Lawlor, Kynan T., Hale, Lorna J., Sun, Jane, Wolvetang, Ernst, Takasato, Minoru, Oshlack, Alicia and Little, Melissa H. (2018). Evaluation of variability in human kidney organoids. Nature Methods, 16 (1), 79-87. doi: 10.1038/s41592-018-0253-2

O'Brien, Lori L., Combes, Alexander N., Short, Kieran M., Lindstrom, Nils O., Whitney, Peter H., Cullen-McEwen, Luise A., Ju, Adler, Abdelhalim, Ahmed, Michos, Odysse, Bertram, John F., Smyth, Ian M., Little, Melissa H. and McMahon, Andrew P. (2018). Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment. Elife, 7 e40392. doi: 10.7554/eLife.40392

Hale, Lorna J., Howden, Sara E., Phipson, Belinda, Lonsdale, Andrew, Er, Pei X., Ghobrial, Irene, Hosawi, Salman, Wilson, Sean, Lawlor, Kynan T., Khan, Shahnaz, Oshlack, Alicia, Quinlan, Catherine, Lennon, Rachel and Little, Melissa H. (2018). 3D organoid-derived human glomeruli for personalised podocyte disease modelling and drug screening. Nature Communications, 9 (1) 5167, 5167. doi: 10.1038/s41467-018-07594-z

Little, Melissa H., Kumar, Santhosh V. and Forbes, Thomas (2018). Recapitulating kidney development: progress and challenges. Seminars in Cell & Developmental Biology, 91, 153-168. doi: 10.1016/j.semcdb.2018.08.015

Short, Kieran M., Combes, Alexander N., Lisnyak, Valerie, Lefevre, James G., Jones, Lynelle K., Little, Melissa H., Hamilton, Nicholas A. and Smyth, Ian M. (2018). Branching morphogenesis in the developing kidney 1 is not impacted by nephron formation or integration. eLife, 7 e38992. doi: 10.7554/eLife.38992

Volovelsky, Oded, Thi Nguyen,, Jarmas, Alison E., Combes, Alexander N., Wilson, Sean B., Little, Melissa H., Witte, David P., Brunskill, Eric W. and Kopan, Raphael (2018). Hamartin regulates cessation of mouse nephrogenesis independently of Mtor. Proceedings of the National Academy of Sciences of the United States of America, 115 (23), 5998-6003. doi: 10.1073/pnas.1712955115

Soo, Joanne Y. -C., Jansen, Jitske, Masereeuw, Rosalinde and Little, Melissa H. (2018). Advances in predictive in vitro models of drug-induced nephrotoxicity. Nature Reviews Nephrology, 14 (6), 378-393. doi: 10.1038/s41581-018-0003-9

Lambert, Ben, MacLean, Adam L., Fletcher, Alexander G., Combes, Alexander N., Little, Melissa H. and Byrne, Helen M. (2018). Bayesian inference of agent-based models: a tool for studying kidney branching morphogenesis. Journal of Mathematical Biology, 76 (7), 1673-1697. doi: 10.1007/s00285-018-1208-z

Hale, Lorna J. and Little, Melissa H. (2018). Shining a light on Alport syndrome. Cell Chemical Biology, 25 (5), 497-498. doi: 10.1016/j.chembiol.2018.05.001

Forbes, Thomas A., Howden, Sara E., Lawlor, Kynan, Phipson, Belinda, Maksimovic, Jovana, Hale, Lorna, Wilson, Sean, Quinlan, Catherine, Ho, Gladys, Holman, Katherine, Bennetts, Bruce, Crawford, Joanna, Trnka, Peter, Oshlack, Alicia, Patel, Chirag, Mallett, Andrew, Simons, Cas and Little, Melissa H. (2018). Patient-iPSC-derived kidney organoids show functional validation of a ciliopathic renal phenotype and reveal underlying pathogenetic mechanisms. American Journal of Human Genetics, 102 (5), 816-831. doi: 10.1016/j.ajhg.2018.03.014

Howden, Sara E., Thomson, James A. and Little, Melissa H. (2018). Simultaneous reprogramming and gene editing of human fibroblasts. Nature Protocols, 13 (5), 875-898. doi: 10.1038/nprot.2018.007

Walton, Sarah L., Singh, Reetu R., Little, Melissa H., Bowles, Josephine, Li, Joan and Moritz, Karen M. (2018). Prolonged prenatal hypoxia selectively disrupts collecting duct patterning and postnatal function in male mouse offspring. The Journal of Physiology, 596 (23), 5873-5889. doi: 10.1113/JP275918

van den Berg, Cathelijne W., Ritsma, Laila, Avramut, M. Cristina, Wiersma, Loes E., van den Berg, Bernard M., Leuning, Danielle G., Lievers, Ellen, Koning, Marije, Vanslambrouck, Jessica M., Koster, Abraham J., Howden, Sara E., Takasato, Minoru, Little, Melissa H. and Rabelink, Ton J. (2018). Renal subcapsular transplantation of PSC-derived kidney organoids induces neo-vasculogenesis and significant glomerular and tubular maturation in vivo. Stem Cell Reports, 10 (3), 751-765. doi: 10.1016/j.stemcr.2018.01.041

Combes, Alexander N., Wilson, Sean, Phipson, Belinda, Binnie, Brandon B., Ju, Adler, Lawlor, Kynan T., Cebrian, Cristina, Walton, Sarah L., Smyth, Ian M., Moritz, Karen M., Kopan, Raphael, Oshlack, Alicia and Little, Melissa H. (2018). Haploinsufficiency for the Six2 gene increases nephron progenitor proliferation promoting branching and nephron number. Kidney International, 93 (3), 589-598. doi: 10.1016/j.kint.2017.09.015

Tam, Oliver H., Pennisi, David, Wilkinson, Lorine, Little, Melissa H., Wazin, Fatima, Wan, Victor L. and Lovicu, Frank J. (2018). Crim1 is required for maintenance of the ocular lens epithelium. Experimental Eye Research, 170, 58-66. doi: 10.1016/j.exer.2018.02.012

Ryan, Danica, Sutherland, Megan R., Flores, Tracey J., Kent, Alison L., Dahlstrom, Jane E., Puelles, Victor G., Bertram, John F., McMahon, Andrew P., Little, Melissa H., Moore, Lynette and Black, Mary Jane (2018). Development of the human fetal kidney from mid to late gestation in male and female infants. EBioMedicine, 27, 275-283. doi: 10.1016/j.ebiom.2017.12.016

Knight, Ken W., Stephenson, Sarah E. M., West, Sue, Delatycki, Martin B., Jones, Cheryl A., Little, Melissa H., Patton, George C., Sawyer, Susan M., Skinner, S. Rachel, Telfer, Michelle M., Wake, Melissa, North, Kathryn N. and Oberklaid, Frank (2017). The kids are OK: it is discrimination, not same-sex parents, that harms children. Medical Journal of Australia, 207 (9), 1-2.e1. doi: 10.5694/mja17.00943

Walton, S. L., Bielefeldt-Ohmann, H., Singh, R. R., Li, J., Paravicini, T. M., Little, M. H. and Moritz, K. M. (2017). Prenatal hypoxia leads to hypertension, renal renin-angiotensin system activation and exacerbates salt-induced pathology in a sex-specific manner. Scientific Reports, 7 (1) 8241, 8241. doi: 10.1038/s41598-017-08365-4

Oxburgh, Leif, Carroll, Thomas J., Cleaver, Ondine, Gossett, Daniel R., Hoshizaki, Deborah K., Hubbell, Jeffrey A., Humphreys, Benjamin D., Jain, Sanjay, Jensen, Jan, Kaplan, David L., Kesselman, Carl, Ketchum, Christian J., Little, Melissa H., McMahon, Andrew P., Shankland, Stuart J., Spence, Jason R., Valerius, M. Todd, Wertheim, Jason A., Wessely, Oliver, Zheng, Ying and Drummond, Iain A. (2017). (Re)Building a kidney. Journal of the American Society of Nephrology, 28 (5), 1370-1378. doi: 10.1681/ASN.2016101077

Little, Melissa H. (2017). Organoids: a Special Issue. Development, 144 (6), 935-937. doi: 10.1242/dev.150292

Lefevre, James G., Chiu, Han S., Combes, Alexander N., Vanslambrouck, Jessica M., Ju, Ali, Hamilton, Nicholas A. and Little, Melissa H. (2017). Self-organisation after embryonic kidney dissociation is driven via selective adhesion of ureteric epithelial cells. Development, 144 (6), 1087-1096. doi: 10.1242/dev.140228

Leuning, Danielle G., Reinders, Marlies E. J., Li, Joan, Peired, Anna J., Lievers, Ellen, de Boer, Hetty C., Fibbe, Willem E., Romagnani, Paola, van Kooten, Cees, Little, Melissa H., Engelse, Marten A. and Rabelink, Ton J. (2017). Clinical-grade isolated human kidney perivascular stromal cells as an organotypic cell source for kidney regenerative medicine. Stem Cells Translational Medicine, 6 (2), 405-418. doi: 10.5966/sctm.2016-0053

Little, Melissa Helen and Kairath, Pamela (2017). Does Renal Repair Recapitulate Kidney Development?. Journal of the American Society of Nephrology, 28 (1), 34-46. doi: 10.1681/ASN.2016070748

Takasato, Minoru and Little, Melissa H. (2016). A strategy for generating kidney organoids: recapitulating the development in human pluripotent stem cells. Developmental Biology, 420 (2), 210-220. doi: 10.1016/j.ydbio.2016.08.024

Little, M. H. (2016). Generating kidney tissue from pluripotent stem cells. Cell Death Discovery, 2 (1) 16053, 1-4. doi: 10.1038/cddiscovery.2016.53

Lefevre, James G., Combes, Alexander N., Little, Melissa H. and Hamilton, Nicholas A. (2016). Analysed cap mesenchyme track data from live imaging of mouse kidney development. Data in Brief, 9, 149-154. doi: 10.1016/j.dib.2016.08.053

Combes, Alexander N., Lefevre, James G., Wilson, Sean, Hamilton, Nicholas A. and Little, Melissa H. (2016). Cap mesenchyme cell swarming during kidney development is influenced by attraction, repulsion, and adhesion to the ureteric tip. Developmental Biology, 418 (2), 297-306. doi: 10.1016/j.ydbio.2016.06.028

Little, Melissa H., Combes, Alexander N. and Takasato, Minoru (2016). Understanding kidney morphogenesis to guide renal tissue regeneration. Nature Reviews Nephrology, 12 (10), 624-635. doi: 10.1038/nrneph.2016.126

Howden, Sara E., McColl, Bradley, Glaser, Astrid, Vadolas, Jim, Petrou, Steven, Little, Melissa H., Elefanty, Andrew G. and Stanley, Edouard G. (2016). A Cas9 variant for efficient generation of indel-free knockin or gene-corrected human pluripotent stem cells. Stem Cell Reports, 7 (3), 508-517. doi: 10.1016/j.stemcr.2016.07.001

Takasato, Minoru, Er, Pei X., Chiu, Han S. and Little, Melissa H. (2016). Generation of kidney organoids from human pluripotent stem cells. Nature Protocols, 11 (9), 1681-1692. doi: 10.1038/nprot.2016.098

Little, Melissa H. and Kairath, Pamela (2016). Regenerative medicine in kidney disease. Kidney International, 90 (2), 289-299. doi: 10.1016/j.kint.2016.03.030

Little, Melissa H. (2016). Growing kidney tissue from stem cells: How far from "party Trick" to medical application?. Cell Stem Cell, 18 (6), 695-698. doi: 10.1016/j.stem.2016.05.015

Phua, Yu Leng, Gilbert, Thierry, Combes, Alexander, Wilkinson, Lorine J. and Little, Melissa H. (2016). Neonatal vascularization and oxygen tension regulate appropriate perinatal renal medulla/papilla maturation. The Journal of Pathology, 238 (5), 665-676. doi: 10.1002/path.4690

Little, Melissa H. (2016). Closing the circle: from organoids back to development. Development, 143 (6), 905-906. doi: 10.1242/dev.136150

Vicente, Catarina and Little, Melissa (2016). An interview with Melissa Little. Development, 143 (6), 907-909. doi: 10.1242/dev.135897

Iyer, Swati, Chou, Fang Yu, Wang, Richard, Chiu, Han Sheng, Raju, Vinay K. Sundar, Little, Melissa H., Thomas, Walter G., Piper, Michael and Pennisi, David J. (2016). Crim1 has cell-autonomous and paracrine roles during embryonic heart development. Scientific Reports, 6 (1) 19832, 19832 .1-19832 .15. doi: 10.1038/srep19832

Takasato, Minoru, Er, Pei X., Chiu, Han S., Maier, Barbara, Baillie, Gregory J., Ferguson, Charles, Parton, Robert G., Wolvetang, Ernst J., Roost, Matthias S., de Sousa Lopes, Susana M. Chuva and Little, Melissa H. (2015). Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis. Nature, 526 (7574), 564-568. doi: 10.1038/nature15695

Little, Melissa H. (2015). The life cycle of the nephron progenitor. Developmental Cell, 35 (1), 5-6. doi: 10.1016/j.devcel.2015.09.023

Vanslambrouck, J. M. and Little, M. H. (2015). Direct transcriptional reprogramming to nephron progenitors. Current Opinion in Genetics and Development, 34, 10-16. doi: 10.1016/j.gde.2015.06.001

Mallett, Andrew, Patel, Chirag, Maier, Barbara, McGaughran, Julie, Gabbett, Michael, Takasato, Minoru, Cameron, Anne, Trnka, Peter, Alexander, Stephen I., Rangan, Gopala, Tchan, Michel C., Caruana, Georgina, John, George, Quinlan, Cathy, McCarthy, Hugh J., Hyland, Valentine, Hoy, Wedy E., Wolvetang, Ernst, Taft, Ryan, Simons, Cas, Healy H. and Little, Melissa (2015). A protocol for the identification and validation of novel genetic causes of kidney disease. BMC Nephrology, 16 (152) 148, 152. doi: 10.1186/s12882-015-0148-8

Zubkov, V. S., Combes, A. N., Short, K. M., Lefevre, J. G., Hamilton, N. A., Smyth, I. M., Little, M. H. and Byrne, H. M. (2015). A spatially-averaged mathematical model of kidney branching morphogenesis. Journal of Theoretical Biology, 379, 24-37. doi: 10.1016/j.jtbi.2015.04.015

Wainwright, Elanor N., Wilhelm, Dagmar, Combes, Alexander N., Little, Melissa H. and Koopman, Peter (2015). ROBO2 restricts the nephrogenic field and regulates Wolffian duct-nephrogenic cord separation. Developmental Biology, 404 (2), 88-102. doi: 10.1016/j.ydbio.2015.05.023

Takasato, Minoru and Little, Melissa H (2015). The origin of the mammalian kidney: Implications for recreating the kidney in vitro. Development (Cambridge), 142 (11), 1937-1947. doi: 10.1242/dev.104802

Little, Melissa H (2015). Improving our resolution of kidney morphogenesis across time and space. Current Opinion in Genetics and Development, 32, 135-143. doi: 10.1016/j.gde.2015.03.001

Georgas, Kylie M., Armstrong, Jane, Keast, Janet R., Larkins, Christine E., McHugh, Kirk M., Southard-Smith, E. Michelle, Cohn, Martin J., Batourina, Ekatherina, Dan, Hanbin, Schneider, Kerry, Buehler, Dennis P., Wiese, Carrie B., Brennan, Jane, Davies, Jamie A., Harding Simon D., Baldock, Richard A., Little, Melissa H., Vezina, Chad M. and Mendelsohn, Cathy (2015). An illustrated anatomical ontology of the developing mouse lower urogenital tract. Development (Cambridge), 142 (10), 1893-1908. doi: 10.1242/dev.117903

Wilkinson, Lorine J., Neal, Calida S., Singh, Reetu R., Sparrow, Duncan B., Kurniawan, Nyoman D., Ju, Adler, Grieve, Stuart M., Dunwoodie, Sally L., Moritz, Karen M. and Little, Melissa H. (2015). Renal developmental defects resulting from in utero hypoxia are associated with suppression of ureteric β-catenin signaling. Kidney International, 87 (5), 975-983. doi: 10.1038/ki.2014.394

Huang, Johnny Xiao, Geraldine Kaeslin, Max Ranall, Blaskovich, Mark, Bernd Becker, Butler, Mark, Little, Melissa H., Lash, Lawrence H. and Cooper, Matthew (2015). Evaluation of biomarkers for in vitro prediction of drug-induced nephrotoxicity: comparison of HK-2, immortalized human proximal tubule epithelial, and primary cultures of human proximal tubular cells. Pharmacology Research and Perspectives, 3 (3) e00148, e00148. doi: 10.1002/prp2.148

Little, Melissa H. and Takasato, Minoru (2015). Generating a self-organizing kidney from pluripotent cells. Current Opinion in Organ Transplantation, 20 (2), 178-186. doi: 10.1097/MOT.0000000000000174

Li, Joan, Ariunbold, Usukhbayar, Suhaimi, Norseha, Sunn, Nana, Guo, Jinjin, McMahon, Jill A., McMahon, Andrew P. and Little, Melissa (2015). Collecting duct-derived cells display mesenchymal stem cell properties and retain selective in vitro and in vivo epithelial capacity. Journal of the American Society of Nephrology, 26 (1), 81-94. doi: 10.1681/ASN.2013050517

Combes, Alexander N., Short, Kieran M., Lefevre, James, Hamilton, Nicholas A., Little, Melissa H. and Smyth, Ian M. (2014). An integrated pipeline for the multidimensional analysis of branching morphogenesis. Nature Protocols, 9 (12), 2859-2879. doi: 10.1038/nprot.2014.193

Bonventre, Joseph V., Boulware, L. Ebony, Dember, Laura M., Freedman, Barry I., Furth, Susan L., Holzman, Lawrence B., Ketchum, Christian J., Little, Melissa H., Mehrotra, Rajnish, Moe, Sharon M., Sands, Jeff M., Sedor, John R., Somlo, Stefan, Star, Robert A., Rys-Sikora, Krystyna E. and Kidney Research National Dialogue (KRND) (2014). The Kidney Research National Dialogue: Gearing up to move forward. Clinical Journal of the American Society of Nephrology, 9 (10), 1806-1811. doi: 10.2215/CJN.07310714

Takasato, Minoru, Vanslambrouck, Jessica M. and Little, Melissa H. (2014). Reprogramming somatic cells to a kidney fate. Seminars In Nephrology, 34 (4), 462-480. doi: 10.1016/j.semnephrol.2014.06.012

Cuffe, J. S. M., Walton, S. L, Singh, R. R, Spiers, J. G., Bielefeldt-Ohmann, H., Wilkinson, L., Little, M. H. and Moritz, K. M. (2014). Mid- to late term hypoxia in the mouse alters placental morphology, glucocorticoid regulatory pathways and nutrient transporters in a sex-specific manner. The Journal of Physiology, 592 (14), 1-15. doi: 10.1113/jphysiol.2014.272856

Short, Kieran M., Combes, Alexander N., Lefevre, James, Ju, Adler L., Georgas, Kylie M., Lamberton, Timothy, Cairncross, Oliver, Rumballe, Bree A., McMahon, Andrew P., Hamilton, Nicholas A., Smyth, Ian M. and Little, Melissa H. (2014). Global quantification of tissue dynamics in the developing mouse kidney. Developmental Cell, 29 (2), 188-202. doi: 10.1016/j.devcel.2014.02.017

Little, Melissa H., Brown, Dennis, Humphreys, Benjamin D., McMahon, Andrew P., Miner, Jeffrey H., Sands, Jeff M., Weisz, Ora A., Mullins, Chris, Hoshizaki, Deborah and Kidney Research National Dialogue (KRND) (2014). Defining kidney biology to understand renal disease. Clinical Journal of the American Society of Nephrology, 9 (4), 809-811. doi: 10.2215/CJN.10851013

Takasato, M., Er, P. X., Becroft, M., Vanslambrouck, J. M., Stanley, E. G., Elefanty, A. G. and Little, M. H. (2014). Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidney. Nature Cell Biology, 16 (1), 118-126. doi: 10.1038/ncb2894

Kopan, Raphael, Chen, Shuang and Little, Melissa (2014). Nephron Progenitor Cells. Shifting the Balance of Self-Renewal and Differentiation.. Current Topics in Developmental Biology, 107, 293-331. doi: 10.1016/B978-0-12-416022-4.00011-1

Paroly, Suneeta S., Wang, Fengwei, Spraggon, Lee, Merregaert, Joseph, Batourina, Ekatherina, Tycko, Benjamin, Schmidt-Ott, Kai M., Grimmond, Sean, Little, Melissa and Mendelsohn, Cathy (2013). Stromal protein Ecm1 regulates ureteric bud patterning and branching. PloS One, 8 (12) e84155, e84155. doi: 10.1371/journal.pone.0084155

Lefevre, J., Marshall, D. J., Combes, A. N., Ju, A. L., Little, M. H. and Hamilton, N. A. (2013). Modelling cell turnover in a complex tissue during development. Journal of Theoretical Biology, 338, 66-79. doi: 10.1016/j.jtbi.2013.08.033

Packard, Adam, Georgas, Kylie, Michos, Odysse, Riccio, Paul, Cebrian, Cristina, Combes, Alexander N., Ju, Adler, Ferrer-Vaquer, Anna, Hadjantonakis, Anna-Katerina, Zong, Hui, Little, Melissa H. and Costantini, Frank (2013). Luminal Mitosis Drives Epithelial Cell Dispersal within the Branching Ureteric Bud. Developmental Cell, 27 (3), 319-330. doi: 10.1016/j.devcel.2013.09.001

Cerruti, Benedetta, Puliafito, Alberto, Shewan, Annette M., Yu, Wei, Combes, Alexander N., Little, Melissa H., Chianale, Federica, Primo, Luca, Serini, Guido, Mostov, Keith E., Celani, Antonio and Gamba, Andrea (2013). Polarity, cell division, and out-of-equilibrium dynamics control the growth of epithelial structures. Journal of Cell Biology, 203 (2), 359-372. doi: 10.1083/jcb.201305044

Hendry, Caroline E., Vanslambrouck, Jessica M., Ineson, Jessica, Suhaimi, Norseha, Takasato, Minoru, Rae, Fiona and Little, Melissa H. (2013). Direct transcriptional reprogramming of adult cells to embryonic nephron progenitors. Journal of the American Society of Nephrology, 24 (9), 1424-1434. doi: 10.1681/ASN.2012121143

Rabelink, Ton J. and Little, Melissa H. (2013). Stromal cells in tissue homeostasis: balancing regeneration and fibrosis. Nature Reviews: Nephrology, 9 (12), 747-753. doi: 10.1038/nrneph.2013.152

Rakoczy, Joanna, Fernandez-Valverde, Selene L., Glazov, Evgeny A., Wainwright, Elanor N., Sato, Tempei, Takada, Shuji, Combes, Alexander N., Korbie, Darren J., Miller, David, Grimmond, Sean M., Little, Melissa H., Asahara, Hiroshi, Mattick, John S., Taft, Ryan J. and Wilhelm, Dagmar (2013). MicroRNAs-140-5p/140-3p modulate leydig cell numbers in the developing mouse testis. Biology of Reproduction, 88 (6) 143, 143. doi: 10.1095/biolreprod.113.107607

Jones, Christina V., Williams, Timothy M., Walker, Kenneth A., Dickinson, Hayley, Sakkal, Samy, Rumballe, Bree A., Little, Melissa H., Jenkin, Graham and Ricardo, Sharon D. (2013). M2 macrophage polarisation is associated with alveolar formation during postnatal lung development. Respiratory Research, 14 (1) 41, 41.1-41.14. doi: 10.1186/1465-9921-14-41

Phua, Yu Leng, Martel, Nick, Pennisi, David J., Little, Melissa H. and Wilkinson, Lorine J. (2013). Distinct sites of renal fibrosis in the Crim1 mutant mice arise from multiple cellular origins. Journal of Pathology, 229 (5), 685-696. doi: 10.1002/path.4155

Davidson, Alan J. and Little, Melissa (2013). Report on the first Asia-Pacific Kidney Development Workshop. Nephrology, 18 (3), 176-176. doi: 10.1111/nep.12026

Rumballe, Bree A, Chiu, Han Sheng, Georgas, Kylie M and Little, Melissa H (2012). Use of in situ hybridization to examine gene expression in the embryonic, neonatal, and adult urogenital system. Methods in Molecular Biology, 886, 223-239.

Weise, Carrie B., Ireland, Sara, Fleming, Nicole L., Yu, Jing, Valerius, M. Todd, Kylie Georgas, Chiu, Han Sheng, Brennan, Jane, Armstrong, Jane, Little, Melissa H., McMahon, Andrew P. and Southard-Smith, E. Michelle (2012). A genome-wide screen to identify transcription factors expressed in pelvic ganglia of the lower urinary tract. Frontiers in Neuroscience, 6 (SEP) Article 130. doi: 10.3389/fnins.2012.00130

Chiu, Han Sheng, York, Philippe J., Wilkinson, Lorine, Zhang, Pumin, Little, Melissa H. and Pennisi, David J. (2012). Production of a mouse line with a conditional Crim1 mutant allele. Genesis, 50 (9), 711-716. doi: 10.1002/dvg.22032

Wilkinson, Lorine, Kurniwan, Nyoman D., Phua, Yu Leng, Nguyen, Michael J., Li, Joan, Galloway, Graham J., Hashitani, Hikaru, Lang, Richard J. and Little, Melissa H. (2012). Association between congenital defects in papillary outgrowth and functional obstruction in Crim1 mutant mice. Journal of Pathology, 227 (4), 499-510. doi: 10.1002/path.4036

Chen, Huijun, Palmer, James S., Thaigarajan, Rathi D., Dinger, Marcel E., Frampton, Emmanuelle, Chiu, Hansheng, Schulz, Alexandra, Spiller, Cassy, Grimmond, Sean M., Little, Melissa H., Koopman, Peter A. and Wilhelm, Ingrid D. (2012). Identification of novel markers of mouse fetal ovary development. PLoS One, 7 (7) e41683, e41683.1-e41683.15. doi: 10.1371/journal.pone.0041683

Hendry, Caroline E. and Little, Melissa H. (2012). Reprogramming the kidney: A novel approach for regeneration. Kidney International, 82 (2), 138-146. doi: 10.1038/ki.2012.68

Pelekanos, Rebecca A., Li, Joan, Gongora, Milena, Chandrakanthan, Vashe, Scown, Janelle, Suhaimi, Norseha, Brooke, Gary, Christensen, Melinda E., Doan, Tram, Rice, Alison M., Osborne, Geoffrey W., Grimmond, Sean M., Harvey, Richard P., Atkinson, Kerry and Little, Melissa H. (2012). Comprehensive transcriptome and immunophenotype analysis of renal and cardiac MSC-like populations supports strong congruence with bone marrow MSC despite maintenance of distinct identities (vol 8, pg 58, 2012). Stem Cell Research, 9 (1), 58-58. doi: 10.1016/j.scr.2012.02.003

Yu, Jing, Valerius, M. Todd, Duah, Mary, Staser, Karl, Hansard, Jennifer K., Guo, Jin-Jin, McMahon, Jill, Vaughan, Joe, Faria, Diane, Georgas, Kylie, Rumballe, Bree, Ren, Qun, Krautzberger, A. Michaela, Junker, Jan P., Thiagarajan, Rathi D., Machanick, Philip, Gray, Paul A., van Oudenaarden, Alexander, Rowitch, David H., Stiles, Charles D., Ma, Qiufu, Grimmond, Sean M., Bailey, Timothy L., Little, Melissa H. and McMahon, Andrew P. (2012). Identification of molecular compartments and genetic circuitry in the developing mammalian kidney. Development, 139 (10), 1863-1873. doi: 10.1242/dev.074005

Little, Melissa H. and McMahon, Andrew P. (2012). Mammalian kidney development: Principles, progress, and projections. Cold Spring Harbor Perspectives in Biology, 4 (5), 1-18. doi: 10.1101/cshperspect.a008300

Pennisi, D. J., Kinna, G., Chiu, H. S., Simmons, D. G., Wilkinson, L. and Little, M. H. (2012). Crim1 has an essential role in glycogen trophoblast cell and sinusoidal-trophoblast giant cell development in the placenta. Placenta, 33 (3), 175-182. doi: 10.1016/j.placenta.2011.12.014

O'Sullivan, Lee, Little, Melissa H., Combes, Alexander N. and Moritz, Karen M. (2012). Epigenetics and developmental programming of adult onset diseases. Pediatric Nephrology, 27 (12), 2175-2182. doi: 10.1007/s00467-012-2108-x

Rae, Fiona K., Suhaimi, Norseha, Li, Joan, Nastasi, Tommaso, Slonimsky, Esfir, Rosenthal, Nadia and Little, Melissa H. (2012). Proximal tubule overexpression of a locally acting IGF isoform, Igf-1Ea, increases inflammation after ischemic injury. Growth Hormone and IGF Research, 22 (1), 6-16. doi: 10.1016/j.ghir.2011.11.002

Davies, Jamie A., Little, Melissa H., Aronow, Bruce, Armstrong, Jane, Brennan, Jane, Lloyd-Macgilp, Sue, Armit, Chris, Harding, Simon, Piu, Xinjun, Roochun, Yogmatee, Haggarty, Bernard, Houghton, Derek, Davidson, Duncan and Baldock, Richard (2012). Erratum: Access and use of the GUDMAP database of genitourinary development. Methods in Molecular Biology, 886, E1-E1. doi: 10.1007/978-1-61779-851-1_36

Pelekanos, Rebecca A., Li, Joan, Gongora, Milena, Chandrakanthan, Vashe, Scown, Janelle, Suhaimi, Norseha, Gary Brooke, Christensen, Melinda E., Doan, Tram, Rice, Alison M., Osborne, Geoffrey W., Grimmond, Sean M., Harvey, Richard P., Atkinson, Kerry and Little, Melissa H. (2012). Comprehensive transcriptome and immunophenotype analysis of renal and cardiac MSC-like populations supports strong congruence with bone marrow MSC despite maintenance of distinct identities. Stem Cell Research, 8 (1), 58-73. doi: 10.1016/j.scr.2011.08.003

Vanslambrouck, Jessica, Li, Joan and Little, Melissa H. (2011). The renal papilla: An enigma in damage and repair. Journal of the American Society of Nephrology, 22 (12), 2145-2147. doi: 10.1681/ASN.2011100984

Rumballe, Bree A., Georgas, Kylie M., Combes, Alexander N., Ju, Adler L., Gilbert, Thierry and Little, Melissa H. (2011). Nephron formation adopts a novel spatial topology at cessation of nephrogenesis. Developmental Biology, 360 (1), 110-122. doi: 10.1016/j.ydbio.2011.09.011

Little, Melissa H. (2011). Renal organogenesis: What can it tell us about renal repair and regeneration?. Organogenesis, 7 (4), 229-241. doi: 10.4161/org.7.4.18057

Thiagarajan, Rathi D., Cloonan, Nicole, Gardiner, Brooke B., Mercer, Tim R., Kolle, Gabriel, Nourbaksh, Ehsan, Wani, Shivangi, Tang, Dave, Krishnan, Keerthana, Georgas, Kylie M., Rumballe, Bree A., Chiu, Han S., Steen, Jason A., Mattick, John S., Little, Melissa H. and Grimmond, Sean M. (2011). Refining transcriptional programs in kidney development by integration of deep RNA-sequencing and array-based spatial profiling. BMC Genomics, 12 (1) 441, 441-1-441-16. doi: 10.1186/1471-2164-12-441

Brunskill, Eric W., Georgas, Kylie, Rumballe, Bree, Little, Melissa H. and Potter, S. Steven (2011). Defining the molecular character of the developing and adult kidney podocyte. PLoS One, 6 (9) e24640, e24640.1-e24640.12. doi: 10.1371/journal.pone.0024640

Alikhan, Maliha A., Jones, Christina V., Williams, Timothy M., Beckhouse, Anthony G., Fletcher , Anne L., Kett, Michelle M., Sakkal, Samy, Samuel, Chrishan S., Ramsay, Robert G., Deane, James A., Wells, Christine A., Little, Melissa H., Hume, David A. and Ricardo, Sharon D. (2011). Colony-stimulating factor-1 promotes kidney growth and repair via alteration of macrophage responses. The American Journal of Pathology, 179 (3), 1243-1256. doi: 10.1016/j.ajpath.2011.05.037

Hendry, Caroline, Rumballe, Bree, Moritz, Karen and Little, Melissa H. (2011). Defining and redefining the nephron progenitor population. Pediatric Nephrology, 26 (9), 1395-1406. doi: 10.1007/s00467-010-1750-4

Harding, Simon D., Armit, Chris, Armstrong, Jane, Brennan, Jane, Cheng, Ying, Haggarty, Bernhard, Houghton, Derek, Lloyd-MacGilp, Sue, Pi, Xingjun, Roochun, Yogmatee, Sharghi, Mehran, Tindal, Christopher, McMahon, Andrew P., Gottesman, Brian, Little, Melissa H., Georgas, Kylie, Aronow, Bruce J., Potter, S. Steven, Brunskill, Eri W., Southard-Smith, E. Michelle, Mendelsohn, Cathy, Baldock, Richard A., Davies, Jamie A. and Davidson, Duncan (2011). The GUDMAP database - an online resource for genitourinary research. Development, 138 (13), 2845-2853. doi: 10.1242/dev.063594

Georgas, K. M., Chiu, H. S., Lesieur, E., Rumballe, B. A. and Little, Melissa H. (2011). Expression of metanephric nephron-patterning genes in differentiating mesonephric tubules. Developmental Dynamics, 240 (6), 1600-1612. doi: 10.1002/dvdy.22640

Combes, A. N., Bowles, J., Feng, C. -W., Chiu, H. S., Khoo, P. L., Jackson, A., Little, M. H., Tam, P. P. L. and Koopman, P. (2011). Expression and functional analysis of Dkk1 during early gonadal development. Sexual Development, 5 (3), 124-130. doi: 10.1159/000327709

Thiagarajan, Rathi D., Georgas, Kylie M., Rumballe, Bree A., Lesieur, Emmanuelle, Chiu, Han Sheng, Taylor, Darrin, Tang, Dave T. P., Grimmond, Sean M. and Little, Melissa H. (2011). Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways. PLoS One, 6 (2) e17286, 1-15. doi: 10.1371/journal.pone.0017286

Lin, S. Adelia, Kolle, Gabriel, Grimmond, Sean M., Zhou, Qi, Doust, Elizabeth, Little, Melissa H., Aronow, Bruce, Ricardo, Sharon D., Pera, Martin F., Bertram, John F. and Laslett, Andrew L. (2010). Subfractionation of differentiating human embryonic stem cell populations allows the isolation of a mesodermal population enriched for intermediate mesoderm and putative renal progenitors. Stem Cells and Development, 19 (10), 1637-1648. doi: 10.1089/scd.2010.0017

Chiu, Han Sheng, Szucsik, John C., Georgas, Kylie M., Jones, Julia L., Rumballe, Bree A., Tang, Dave, Grimmond, Sean M., Lewis, Alfor G., Aronow, Bruce J., Lessard, James L. and Little, Melissa H. (2010). Comparative gene expression analysis of genital tubercle development reveals a putative appendicular Wnt7 network for the epidermal differentiation. Developmental Biology, 344 (2), 1071-1087. doi: 10.1016/j.ydbio.2010.05.495

Lusis, M, Li, J, Ineson, J, Christensen, ME, Rice, A and Little, MH (2010). Isolation of clonogenic, long-term self renewing embryonic renal stem cells. Stem Cell Research, 5 (1), 23-39. doi: 10.1016/j.scr.2010.03.003

Rumballe, Bree, Georgas, Kylie, Wilkinson, Lorine and Little, Melissa (2010). Molecular anatomy of the kidney: What have we learned from gene expression and functional genomics?. Pediatric Nephrology, 25 (6), 1005-1016. doi: 10.1007/s00467-009-1392-6

Williams, Timothy M., Little, Melissa H. and Ricardo, Sharon D. (2010). Macrophages in renal development, injury, and repair. Seminars in Nephrology, 30 (3), 255-267. doi: 10.1016/j.semnephrol.2010.03.011

Sims-Lucas, Sunder, Young, Richard J., Martinez, Gemma, Taylor, Darrin, Grimmond, Sean M., Teasdale, Rohan, Little, Melissa H., Bertram, John F. and Caruana, Georgina (2010). Redirection of renal mesenchyme to stromal and chondrocytic fates in the presence of TGF-β2. Differentiation, 79 (4-5), 272-284. doi: 10.1016/j.diff.2010.01.004

Little, Melissa, Georgas, Kylie, Pennisi, David and Wilkinson, Lorine (2010). Kidney development: Two tales of tubulogenesis. Current Topics in Developmental Biology, 90 (C), 193-229. doi: 10.1016/S0070-2153(10)90005-7

Wilkinson, L, Gilbert, T, Sipos, A, Toma, I, Pennisi, D. J., Peti-Peterdi, J and Little, M. H. (2009). Loss of renal microvascular integrity in postnatal Crim1 hypomorphic transgenic mice. Kidney International, 76 (11), 1161-1171. doi: 10.1038/ki.2009.345

Little, M. H. and Bertram, J. F. (2009). Is there such a thing as a renal stem cell?. Journal of the American Society of Nephrology, 20 (10), 2112-2117. doi: 10.1681/ASN.2009010066

Little, Melissa and Rae, Fiona (2009). Review article: Potential cellular therapies for renal disease: Can we translate results from animal studies to the human condition?. Nephrology, 14 (6), 544-553. doi: 10.1111/j.1440-1797.2009.01144.x

Georgas, Kylie, Rumballe, Bree, Valerius, M. Todd, Chiu, Han Sheng, Thiagarajan, Rathi D., Lesieur, Emmanuelle, Aronow, Bruce J., Brunskill, Eric W., Combes, Alexander N., Tang, Dave, Taylor, Darrin, Grimmond, Sean M., Potter, S. Steven, McMahon, Andrew P. and Little, Melissa H. (2009). Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment. Developmental Biology, 332 (2), 273-286. doi: 10.1016/j.ydbio.2009.05.578

Combes, Alexander N., Lesieur, Emmanuelle, Harley, Vincent R., Sinclair, Andrew H., Little, Melissa H., Wilhelm, Dagmar and Koopman, Peter (2009). Three-dimensional visualization of testis cord morphogenesis, a novel tubulogenic mechanism in development. Developmental Dynamics, 238 (5), 1033-1041. doi: 10.1002/dvdy.21925

Brunskill, Eric W., Aronow, Bruce J., Georgas, Kylie, Rumballe, Bree, Valerius, M. Todd, Aronow, Jeremy, Kaimal, Vivek, Jegga, Anil G., Yu, Jing, Grimmond, Sean, McMahon, Andrew P., Patterson, Larry T., Little, Melissa H. and Potter, S. Steven (2009). Atlas of Gene Expression in the Developing Kidney at Microanatomic Resolution (DOI:10.1016/j.devcel.2008.09.007). Developmental Cell, 16 (3), 482. doi: 10.1016/j.devcel.2009.02.014

Poulsom, Richard and Little, Melissa H. (2009). Parietal epithelial cells regenerate podocytes. Journal of the American Society of Nephrology, 20 (2), 231-233. doi: 10.1681/ASN.2008121279

Hopkins, C., Li, J., Rae, F. and Little, M. H. (2009). Stem cell options for kidney disease. Journal of Pathology, 217 (2), 265-281. doi: 10.1002/path.2477

Brunskill, E. W., Aronow, B. J., Georgas, K., Rumballe, B., Valerius, M. T., Kaimal, V., Jegga, A. G., Grimmond, S., McMahon, A. P., Patterson, L. T., Little, M. H. and Potter, S. S. (2008). Atlas of Gene Expression in the Developing Kidney at Microanatomic Resolution. Developmental Cell, 15 (5), 781-791. doi: 10.1016/j.devcel.2008.09.007

Georgas, Kylie, Rumballe, Bree, Wilkinson, Lorine, Chiu, Han Sheng, Lesieur, Emmanuelle, Gilbert, Thierry and Little, Melissa H. (2008). Use of dual section mRNA in situ hybridization/immunohistochemistry to clarify gene expression patterns during the early stages of nephron development in the embryo and in the mature nephron of the adult mouse kidney. Histochemistry and Cell Biology, 130 (5), 927-942. doi: 10.1007/s00418-008-0454-3

Little, M. H. (2008). Tracing the life of the kidney tubule - re-establishing dogma and redirecting the options.. Cell Stem Cell, 2 (3), 191-192. doi: 10.1016/j.stem.2008.02.007

McMahon, A. P,, Aronow, B. J., Davidson, D. R., Davies, J. A., Gaido, K. W., Grimmond, S., Lessard, J. L., Little, M. H., Zhang, P., Potter, S.S. and Wilder, E.L. (2008). GUDMAP: the genitourinary developmental molecular anatomy project. Journal of the American Society of Nephrology, 19 (4), 667-671. doi: 10.1681/ASN.2007101078

Rumballe, Bree, Georgas, Kylie and Little, Melissa H. (2008). High-throughput paraffin section in situ hybridization and dual immunochemistry on mouse tissues. Cold Spring Harbor Protocols, 3 (7), 1-7. doi: 10.1101/pdb.prot5030

Little, MH, Brennan, J, Georgas, K, Davies, JA, Davidson, DR, Baldock, RA, Beverdam, A, Bertram, JF, Capel, B, Chiu, HS, Clements, D, Cullen-McEwen, L, Fleming, J, Gilbert, T, Herzlinger, D, Houghton, D, Kaufman, MH, Kleymenova, E, Koopman, PA, Lewis, AG, McMahon, AP, Mendelsohn, CL, Mitchell, EK, Rumballe, BA, Sweeney, DE, Valerius, MT, Yamada, G, Yang, Y and Yu, J (2007). A high-resolution anatomical ontology of the developing murine genitourinary tract (vol 7, pg 680, 2007). Gene Expression Patterns, 8 (1), 47-50. doi: 10.1016/j.modgep.2007.07.003

Little, Melissa H., Brennan, Jane, Georgas, Kylie, Davies, Jamie A., Davidson, Duncan R., Baldock, Richard A., Beverdam, Annemiek, Bertram, John F., Capel, Blanche, Chiu, Han Sheng, Clements, Dave, Cullen-McEwen, Luise, Fleming, Jean, Gilbert, Thierry, Herzlinger, Doris, Houghton, Derek, Kaufman, Matt H., Kleymenova, Elena, Koopman, Peter A., Lewis, Alfor G., McMahon, Andrew P., Mendelsohn, Cathy L., Mitchell, Eleanor K., Rumballe, Bree A., Sweeney, Derina E., Valerius, M. Todd, Yamada, Gen, Yang, Yiya and Yu, Jing (2007). A high-resolution anatomical ontology of the developing murine genitourinary tract. Gene Expression Patterns, 7 (6), 680-699. doi: 10.1016/j.modgep.2007.03.002

Pennisi, David J., Wilkinson, Lorine, Kolle, Gabriel, Sohaskey, Michael L., Gillinder, Kevin, Piper, Michael J., McAvoy, John W., Lovicu, Frank J. and Little, Melissa H. (2007). Crim1(KST264/KST264) mice display a disruption of the Crim1 gene resulting in perinatal lethality with defects in multiple organ systems. Developmental Dynamics, 236 (2), 502-511. doi: 10.1002/dvdy.21015

Little, Melissa H. (2007). Biotechnology in Australia: Part of the Knowledge-based Economy. Journal of Biolaw and Business (Special supplement : Australia), 3-5.

Little, Melissa H. and Free, M. (2007). Australian Stem Cell Centre: Australia's experiment in a Biotechnology Centre of Excellence. Journal of Biolaw and Business, Special Supplement: Australia, 28-35.

Rae, Fiona, Woods, Kyra, Sasmono, Tedjo, Campanale, Naomi, Taylor, Darrin, Ovchinnikov, Dmitry A., Grimmond, Sean M., Hume, David A., Ricardo, Sharon D. and Little, Melissa H. (2007). Characterisation and trophic functions of murine embryonic macrophages based upon the use of a Csf1r-EGFP transgene reporter. Developmental Biology, 308 (1), 232-246. doi: 10.1016/j.ydbio.2007.05.027

Wilkinson, Lorine, Gilbert, Thierry, Kinna, Genevieve, Ruta, Leah-Anne, Pennisi, David, Kett, Michelle and Little, Melissa H. (2007). Crim1(KST264/KST264) mice implicate Crim1 in the regulation of vascular endothelial growth factor-A activity during glomerular vascular development. Journal of The American Society of Nephrology, 18 (6), 1697-1708. doi: 10.1681/ASN.2006091012

Little, M. H., Hall, W. D. and Orlandi, A. (2006). Delivering on the promise of human stem cell research: what are the real barriers?. EMBO Reports, 7 (12), 1188-1192. doi: 10.1038/sj.embor.7400861

Martinez, Gemma, Georgas, Kylie, Challen, Grant A., Rumballe, Bree, Davis, Melissa J., Taylor, Darrin, Teasdale, Rohan D., Grimmond, Sean M. and Little, Melissa H. (2006). Definition and spatial annotation of the dynamic secretome during early kidney development. Developmental Dynamics, 235 (6), 1709-1719. doi: 10.1002/dvdy.20740

Caruana, Georgina, Cullen-McEwen, Luise, Nelson, Amy L., Kostoulias, Xenia, Woods, Kyra, Gardiner, Brooke, Davis, Melissa J., Taylor, Darrin F., Teasdale, Rohan D., Grimmond, Sean M., Little, Melissa H. and Bertram, John F. (2006). Spatial gene expression in the T-stage mouse metanephros. Gene Expression Patterns, 6 (8), 807-825. doi: 10.1016/j.modgep.2006.02.001

Mitchell, E. K. L., Taylor, D. F., Woods, K., Davis, M. J., Nelson, A. L., Teasdale, R. D., Grimmond, S. M., Little, M. H., Bertram, J. F. and Caruana, G. (2006). Differential gene expression in the developing mouse ureter. Gene Expression Patterns, 6 (5), 519-538. doi: 10.1016/j.modgep.2005.10.008

Little, M. H. (2006). Regrow or repair: Potential regenerative therapies for the kidney. Journal Of The American Society Of Nephrology, 9 (9), 2390-2401. doi: 10.1681/ASN.2006030218

Kinna, G., Kolle, G., Carter, A., Key, B., Lieschke, G. J., Perkins, A. and Little, M. H. (2006). Knockdown of zebrafish crim1 results in a bent tail phenotype with defects in somite and vascular development. Mechanisms of Development, 123 (4), 277-287. doi: 10.1016/j.mod.2006.01.003

Challen, Grant A., Bertoncello, Ivan, Deane, James A., Ricardo, Sharon. D. and Little, Melissa H. (2006). Kidney side population reveals multilineage potential and renal functional capacity but also cellular heterogeneity. Journal of The American Society of Nephrology, 17 (7), 1896-1912. doi: 10.1681/ASN.2005111228

Challen, Grant A. and Little, Melissa H. (2006). A side order of stem cells: The SP phenotype. Stem Cells, 24 (1), 3-12. doi: 10.1634/stemcells.2005.0116

Torban, E., Dziarmaga, A., Iglesias, D., Chu, L. L., Vassilieva, T., Little, M., Eccles, M., Discenza, M., Pelletier, J. and Goodyer, P. (2006). PAX2 activates WNT4 expression during mammalian kidney development. Journal of Biological Chemistry, 281 (18), 12705-12712. doi: 10.1074/jbc.M513181200

Cochrane, Anita L., Kett, Michelle M., Samuel, Chrishan S., Campanale, Naomi V., Anderson, Warwick P., Hume, David A., Little, Melissa H., Bertram, John F. and Ricardo, Sharon D. (2005). Renal structural and functional repair in a mouse model of reversal of ureteral obstruction. Journal of The American Society of Nephrology, 16 (12), 3623-3630. doi: 10.1681/ASN.2004090771

Gao, X. B., Chen, X., Taglienti, M., Rumballe, B., Little, M. H. and Kreidberg, J. A. (2005). Angioblast-mesenchyme induction of early kidney development is mediated by Wt1 and Vegfa. Development, 132 (24), 5437-5449. doi: 10.1242/dev.02095

Armstrong, S. R., Campbell, G. R., Campbell, J. H. and Little, M. H. (2005). Establishment of metanephros transplantation in mice highlights contributions by both nephrectomy and pregnancy to developmental progression. Nephron Experimental Nephrology, 101 (4), E155-E164. doi: 10.1159/000087939

Challen, G., Gardiner, B., Caruana, G., Kostoulias, X., Martinez, G., Crowe, M., Taylor, D. F., Bertram, J., Little, M. and Grimmond, S. M. (2005). Temporal and spatial transcriptional programs in murine kidney development. Physiological Genomics, 23 (2), 159-171. doi: 10.1152/physiolgenomics.00043.2005

Mittaz, L., Ricardo, S., Martinez, G., Kola, I., Kelly, D. J., Little, M. H., Hertzog, P. J. and Pritchard, M. A. (2005). Neonatal calyceal dilation and renal fibrosis resulting from loss of Adamts-1 in mouse kidney is due to a developmental dysgenesis. Nephrology Dialysis Transplantation, 20 (2), 419-423. doi: 10.1093/ndt/gfh603

Challen, G. A., Martinez, G., Davis, M. J., Taylor, D. F., Crowe, M., Teasdale, R. D., Grimmond, S. M. and Little, M. H. (2004). Identifying the molecular phenotype of renal progenitor cells. Journal of The American Society of Nephrology, 15 (9), 2344-2357. doi: 10.1097/01.ASN.0000136779.17837.8F

Miyashita, T., Yeo, S., Hirate, Y., Segawa, H., Wada, H., Little, M. H., Yamada, T., Takahashi, N. and Okamoto, H. (2004). PlexinA4 is necessary as a downstream target of Islet2 to mediate Slit signaling for promotion of sensory axon branching. Development, 131 (15), 3705-3715. doi: 10.1242/dev.01228

Yeo, Sang-Yeob, Miyashita, Toshio, Fricke, Cornelia, Little, Melissa H., Yamada, Toshiya, Kuwada, John Y., Huh, Tae-Lin, Chien, Chi-Bin and Okamoto, Hitoshi (2004). Involvement of Islet-2 in the Slit signaling for axonal branching and defasciculation of the sensory neurons in embryonic zebrafish. Mechanisms of Development, 121 (4), 315-324. doi: 10.1016/j.mod.2004.03.006

Rae, F. K., Martinez, G., Gillinder, K. R., Smith, A., Shooter, G., Forrest, A. R., Grimmond, S. M. and Little, M. H. (2004). Anlaysis of complementary expression profiles following WT1 induction versus repression reveals the cholesterol/fatty acid synthetic pathways as a possible major target of WT1. Oncogene, 23 (17), 3067-3079. doi: 10.1038/sj.onc.1207360

Wilkinson, Lorine, Kolle, Gabriel, Wen, Daying, Piper, Michael, Scott, Julie and Little, Melissa (2003). CRIM1 Regulates the Rate of Processing and Delivery of Bone Morphogenetic Proteins to the Cell Surface. Journal of Biological Chemistry, 278 (36), 34181-34188. doi: 10.1074/jbc.M301247200

Samuel, T., Douglas-Denton, R., Hoy, W. E., Hughson, M., Little, M. and Bertram, J. F. (2003). Nephron endowment and potential therapies for nephron deficit. Today's Life Science, 15 (1), 30-33.

Kolle, G., Jansen, A., Yamada, T. and Little, M. (2003). In ovo electroporation of Crim1 in the developing chick spinal cord. Developmental Dynamics, 226 (1), 107-111. doi: 10.1002/dvdy.10204

Vajjhala, P. R., Macmillan, E., Gonda, T. and Little, M. H. (2003). The Wilms' Tumour Suppressor Protein, WT1, Undergoes CRM1-independent Nucleocytoplasmic Shuttling. FEBS Letters, 554 (1-2), 143-148. doi: 10.1016/S0014-5793(03)01144-X

Piper, Michael and Little, Melissa (2003). Movement through slits: Cellular migration via the Slit family. BioEssays, 25 (1), 32-38. doi: 10.1002/bies.10199

Gross, I., Morrison, D. J., Hyink, D. P., Georgas, K., English, M. A., Mericskay, M., Hosono, S., Sasson, D., Wilson, P. D., Little, M. and Licht, J. D. (2003). The receptor tyrosine kinase regulator sprouty1 is a target of the tumor suppressor WT1 and important for kidney development. Journal of Biological Chemistry, 278 (42), 41420-41430. doi: 10.1074/jbc.M306425200

Piper, Michael, Nurcombe, Victor, Reid, Kate, Bartlett, Perry and Little, Melissa (2002). N-terminal Slit2 promotes survival and neurite extension in cultured peripheral neurons. Neuroreport, 13 (17), 2375-2378. doi: 10.1097/01.wnr.0000049602.07559.20

Smith, E., Hargrave, M., Yamada, T., Begley, C. G. and Little, M. H. (2002). Coexpression of SCL and GATA3 in the V2 Interneurons of the developing mouse spinal cord. Developmental Dynamics, 224 (2), 231-237. doi: 10.1002/dvdy.10093

Sim, E. U. H., Smith, A. G., Szilagi, E., Rae, F., Ioannou, P., Lindsay, M. H. and Little, M. H. (2002). Wnt-4 regulation by the Wilms' tumour suppressor gene, WT1. Oncogene, 21 (19), 2948-2960. doi: 10.1038/sj/onc/1205373

Piper, Michael, Nurcombe, Victor, Wilkinson, Lorine and Little, Melissa (2002). Exogenous Slit2 does not affect ureteric branching or nephron formation during kidney development. International Journal of Developmental Biology, 46 (4), 545-550.

Piper, Michael and Little, Melissa (2002). Movement through slits: cellular migration via the Slit family. BioEssays, 25 (1), 32-38. doi: 10.1002/bies.10199

Little, Melissa, Rumballe, Bree, Georgas, Kylie, Yamada, Toshiya and Teasdale, Rohan D. (2002). Conserved modularity and potential for alternate splicing in mouse and human Slit genes. International Journal of Developmental Biology, 46 (4), 385-391.

Little, Melissa H. (2002). Book Review: Molecular Genetics of Cancer 2nd Edition. Cancer Forum, 26 (1), 56-57.

Little, Melissa H., Wilkinson, Lorine, Brown, Darren L., Piper, Michael, Yamada, Toshiya and Stow, Jennifer L. (2001). Dual trafficking of Slit3 to mitochondria and cell surface demonstrates novel localization for Slit protein. American Journal of Physiology-cell Physiology, 281 (2), C486-C495. doi: 10.1152/ajpcell.2001.281.2.c486

Yeo, S. Y., Little, M. H., Yamada, T., Miyashita, T., Halloran, M. C., Kuwada, J. Y., Huh, T. L. and Okamoto, H. (2001). Overexpression of a Slit homologue impairs convergent extension of the mesoderm and causes cyclopia in embryonic zebrafish. Developmental Biology, 230 (1), 1-17. doi: 10.1006/dbio.2000.0105

Georgas, Kylie, Bowles, Josephine, Yamada, Toshiya, Koopman, Peter and Little, Melissa H. (2000). Characterisation of Crim1 expression in the developing mouse urogenital tract reveals a sexually dimorphic gonadal expression pattern. Developmental Dynamics, 219 (4), 582-587. doi: 10.1002/1097-0177(2000)9999:9999<::AID-DVDY1072>3.0.CO;2-I

Piper, M, Georgas, K, Yamada, T and Little, M (2000). Expression of the vertebrate Slit gene family and their putative receptors, the Robo genes, in the developing murine kidney. Mechanism of Development, 94 (1-2), 213-217. doi: 10.1016/S0925-4773(00)00313-0

Little, Melissa H., Carman, Gregory and Donaldson, Eric (2000). Novel WT1 exon 9 mutation (D396Y) in a patient with early onset Denys Drash syndrome. Human Mutation, 15 (4), 389-389. doi: 10.1002/(SICI)1098-1004(200004)15:4<389::AID-HUMU29>3.0.CO;2-E

Hargrave, M, James, K, Nield, K, Toomes, C, Georgas, K, Sullivan, T, Verzijl, HTFM, Oley, CA, Little, M, De Jonghe, P, Kwon, JM, Kremer, H, Dixon, MJ, Timmerman, V, Yamada, T and Koopman, P (2000). Fine mapping of the neurally expressed gene SOX14 to human 3q23, relative to three congenital diseases. Human Genetics, 106 (4), 432-439. doi: 10.1007/s004390000266

Bellomo, D., Headrick, J. P., Silins, G. U., Paterson, C. A., Thomas, P. S., Gartside, M., Mould, A., Cahill, M. M., Tonks, I. D., Grimmond, S. M., Wells, C. A., Little, M. H., Cummings, M. C., Hayward, N. K. and Kay, G. F. (2000). Mice lacking the vascular endothelial growth factor-B gene (Vegfb) have smaller hearts, dysfunctional coronary vasculature, and impaired recovery from cardiac ischemia. Circulation Research, 86 (2), E29-E35.

Kolle, G., Georgas, K., Holmes, G. P., Little, Melissa H. and Yamada, T. (2000). CRIM1, a novel gene encoding a cysteine-rich repeat protein, is developmentally regulated and implicated in vertebrate CNS development and organogenesis. Mechanisms of Development, 90 (2), 181-193. doi: 10.1016/S0925-4773(99)00248-8

Lovicu, F. J., Kolle, G., Yamada, T., Little, M. H. and McAvoy, J. W. (2000). Expression of Crim1 during murine ocular development. Mechanisms of Development, 94 (1-2), 261-265. doi: 10.1016/S0925-4773(00)00292-6

Passey, Robert J., Williams, Elizabeth, Lichanska, Agnieszka M., Wells, Christine, Hu, Shengping, Geczy, Carolyn L., Little, Melissa H. and Hume, David A. (1999). A null mutation in the inflammation-associated S100 protein S100A8 causes early resorption of the mouse embryo. Journal of Immunology, 163 (4), 2209-2216.

Little, Melissa, Holmes, Greg and Walsh, Patrick (1999). WT1: what has the last decade told us?. BioEssays, 21 (3), 191-202. doi: 10.1002/(SICI)1521-1878(199903)21:3<191::AID-BIES3>3.0.CO;2-8

Patek, C. E., Little, M. H., Fleming, S., Miles, C., Charlieu, J. P., Clarke, A. R., Miyagawa, K., Christie, S., Doig, J., Harrison, D. J., Porteous, D. J., Brookes, A. J., Hooper, M. L. and Hastie, N. D. (1999). A zinc finger truncation of murine WT1 results in the characteristic urogenital abnormalities of denys-drash syndrome. Proceedings of the National Acadamy of Sciences of the United State of America, 96 (6), 2931-2936. doi: 10.1073/pnas.96.6.2931

Georgas, K. M., Burridge, Linda M., Smith, K., Holmes, Greg P., Chenevix-Trench, G., Ioannou, P. A. and Little, M. H. (1999). Assignment of the human slit homologue SLIT2 to human chromosome band 4p15.2. Cytogenetics and Cell Genetics, 86 (3-4), 246-247. doi: 10.1159/000015351

Holmes, GP, Negus, K, Burridge, L, Raman, S, Algar, E, Yamada, T and Little, MH (1998). Distinct but overlapping expression patterns of two vertebrate slit homologs implies functional roles in CNS development and organogenesis. Mechanisms of Development, 79 (1-2), 57-72. doi: 10.1016/S0925-4773(98)00174-9

Miyagawa, K, Kent, J, Moore, A, Charlieu, JP, Little, MH, Williamson, KA, Kelsey, A, Brown, KW, Hassam, S, Briner, J, Hayashi, Y, Hirai, H, Yazaki, Y, van Heyningen, V and Hastie, ND (1998). Loss of WT1 function leads to ectopic myogenesis in Wilms' tumour. Nature Genetics, 18 (1), 15-17. doi: 10.1038/ng0198-15

Law, MH, Algar, E and Little, M (1997). Allelic imbalance at chromosome 1q21 in Wilms tumor. Cancer Genetics and Cytogenetics, 97 (1), 54-59. doi: 10.1016/S0165-4608(96)00342-1

Holmes, G, Boterashvili, S, English, M, Wainwright, B, Licht, J and Little, M (1997). Two N-terminal self-association domains are required for the dominant negative transcriptional activity of WT1 Denys-Drash mutant proteins. Biochemical and Biophysical Research Communications, 233 (3), 723-728. doi: 10.1006/bbrc.1997.6545

Little, M. and Wells, C. (1997). A clinical overview of WT1 gene mutations. Human Mutation, 9 (3), 209-225. doi: 10.1002/(SICI)1098-1004(1997)9:3<209::AID-HUMU2>3.0.CO;2-2

Little, MH, Holmes, G, Pell, L, Caricasole, A, Duarte, A, Law, M, Ward, A and Wainwright, B (1996). A novel target for the Wilms' tumour suppressor protein (WT1) is bound by a unique combination of zinc fingers. Oncogene, 13 (7), 1461-1469.

Caricasole, A, Duarte, A, Larsson, SH, Hastie, ND, Little, M, Holmes, G, Todorov, I and Ward, A (1996). RNA binding by the Wilms tumor suppressor zinc finger proteins. Proceedings of the National Academy of Sciences of the United States of America, 93 (15), 7562-7566. doi: 10.1073/pnas.93.15.7562

Kennedy, D, Ramsdale, T, Mattick, J and Little, M (1996). An RNA recognition motif in Wilms' tumour protein (WT1) revealed by structural modelling. Nature Genetics, 12 (3), 329-332. doi: 10.1038/ng0396-329

Negus, K, Holmes, GH, Wicking, C, Wainwright, BJ and Little, MH (1996). +P5(D1S3309E), a novel target binding site for the Wilms' tumour suppressor 1 (WT1) gene, maps to human chromosome 1q21->q22. Cytogenetics and Cell Genetics, 72 (4), 306-309. doi: 10.1159/000134210

Little, M and Wainwright, B (1995). Methylation and P16 - Suppressing the Suppressor. Nature Medicine, 1 (7), 633-634. doi: 10.1038/nm0795-633

Little, M, Holmes, G, Bickmore, W, Vanheyningen, V, Hastie, N and Wainwright, B (1995). Dna-Binding Capacity of the Wt1 Protein Is Abolished by Denys-Drash Syndrome Wt1 Point Mutations. Human Molecular Genetics, 4 (3), 351-358. doi: 10.1093/hmg/4.3.351

Byrne, JA, Simms, LA, Little, MH, Algar, EM and Smith, PJ (1993). 3 Nonoverlapping Regions of Chromosome Arm 11p Allele Loss Identified in Infantile Tumors of Adrenal and Liver. Genes Chromosomes & Cancer, 8 (2), 104-111. doi: 10.1002/gcc.2870080207

Little, MH, Williamson, KA, Mannens, M, Kelsey, A, Gosden, C, Hastie, ND and Vanheyningen, V (1993). Evidence That Wt1 Mutations in Denys - Drash Syndrome Patients May Act in a Dominant-Negative Fashion. Human Molecular Genetics, 2 (3), 259-264. doi: 10.1093/hmg/2.3.259

Bickmore, WA, Oghene, K, Little, MH, Seawright, A, Vanheyningen, V and Hastie, ND (1992). Modulation of Dna-Binding Specificity by Alternative Splicing of the Wilms-Tumor Wt1 Gene Transcript. Science, 257 (5067), 235-237. doi: 10.1126/science.1321494

Little, MH, Prosser, J, Condie, A, Smith, PJ, Vanheyningen, V and Hastie, ND (1992). Zinc Finger Point Mutations Within the Wt1 Gene in Wilms-Tumor Patients. Proceedings of the National Academy of Sciences of the United States of America, 89 (11), 4791-4795. doi: 10.1073/pnas.89.11.4791

Byrne, JA, Little, MH and Smith, PJ (1992). The M1-Subunit of Ribonucleotide Reductase Refines Mapping of Genetic Rearrangements At Chromosome-11p15. Cancer Genetics and Cytogenetics, 59 (2), 206-209. doi: 10.1016/0165-4608(92)90216-U

Little, MH, Dunn, R, Byrne, JA, Seawright, A, Smith, PJ, Pritchardjones, K, Vanheyningen, V and Hastie, ND (1992). Equivalent Expression of Paternally and Maternally Inherited Wt1 Alleles in Normal Fetal Tissue and Wilms-Tumors. Oncogene, 7 (4), 635-641.

Little, MH, Clarke, J, Byrne, J, Dunn, R and Smith, PJ (1992). Allelic Loss On Chromosome 11p Is a Less Frequent Event in Bilateral Than in Unilateral Wilms-Tumors. European Journal of Cancer, 28A (11), 1876-1880. doi: 10.1016/0959-8049(92)90027-Y

Little, M, Vanheyningen, V and Hastie, N (1991). Genetic Imprinting - Dads and Disomy and Disease. Nature, 351 (6328), 609-610. doi: 10.1038/351609a0

Kozman, HM, Clarke, JM, Little, MH and Smith, PJ (1989). Molecular Genetic-Evidence for Common Pathogenesis of Childhood and Adult Wilms Tumor. Cancer Genetics and Cytogenetics, 38 (1), 121-125. doi: 10.1016/0165-4608(89)90172-6

Little, MH, Thomson, DB, Hayward, NK and Smith, PJ (1988). Loss of Alleles On the Short Arm of Chromosome-11 in a Hepatoblastoma From a Child with Beckwith-Wiedemann Syndrome. Human Genetics, 79 (2), 186-189. doi: 10.1007/BF00280564

Hayward, NK, Keegan, R, Nancarrow, DJ, Little, MH, Smith, PJ, Gardiner, RA, Seymour, GJ, Kidson, C and Lavin, MF (1988). C-Ha-Ras-1 Alleles in Bladder-Cancer, Wilms Tumor and Malignant-Melanoma. Human Genetics, 78 (2), 115-120. doi: 10.1007/BF00278178

Hayward, NK, Little, MH, Mortimer, RH, Clouston, WM and Smith, PJ (1988). Generation of Homozygosity At the C-Ha-Ras-1 Locus On Chromosome-11p in An Adrenal Adenoma From An Adult with Wiedemann-Beckwith Syndrome. Cancer Genetics and Cytogenetics, 30 (1), 127-132. doi: 10.1016/0165-4608(88)90100-8

Little, MH, Ablett, G and Smith, PJ (1987). Enhanced Expression of Insulin-Like Growth Factor-Ii Is Not a Necessary Event in Wilms-Tumor Progression. Carcinogenesis, 8 (6), 865-868. doi: 10.1093/carcin/8.6.865

Little, MH and Sernia, C (1987). Production and Metabolic-Clearance of Angiotensinogen in Conscious Rats as Measured by Steady-State Isotope-Dilution. Journal of Endocrinology, 112 (3), 391-397. doi: 10.1677/joe.0.1120391

Djenoune, Lydia, Schenk, Heiko J., Hegermann, Jan, Little, Melissa H. and Drummond, Iain A. (2021). Autonomous Calcium Signaling in Human and Zebrafish Podocytes Controls Kidney Filtration Barrier Morphogenesis. Kidney Week, Philadelphia, PA United States, 1-5 November 2023. Washington, DC United States: American Society of Nephrology. doi: 10.1681/asn.20213210s1230a

Chesor, Musleeha, Tuffin, Jack P., May, Carl J., Ghobrial, Irene, Little, Melissa H., Saleem, Moin and Welsh, Gavin I. (2021). Recurrent Nephrotic Plasma Activates Pro-Fibrotic Signalling Pathways Downstream of Protease-Activated Receptor 1. Kidney Week, Philadelphia, PA United States, 1-5 November 2023. Washington, DC United States: American Society of Nephrology. doi: 10.1681/asn.20213210s1519c

Vanslambrouck, Jessica M., Tan, Ker sin, Wilson, Sean, Groenewegen, Ella, Neil, Jessica A., Rudraraju, Rajeev, Scurr, Michelle, Howden, Sara E., Subbarao, Kanta and Little, Melissa H. (2021). Maturation-Enhanced Proximal Tubules Enable Functionality, Toxicity Screening, and Infectious Disease Modeling in Kidney Organoids. Kidney Week, Philadelphia, PA United States, 1-5 November 2023. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1681/asn.20213210s1235c

Little, Melissa H., Er, Pei X., Phipson, Belinda, Vanslambrouck, Jessica, Howden, Sara, Hale, Lorna, Takasato, Minoru and Oshlack, A. (2018). Optimisation of Kidney Organoids as a Reproducible and Developmentally Accurate Model of Human Kidney Development and Disease. Joint 10th Annual Scientific Meeting of the Australian-Gene-and-Cell-Therapy-Society (AGCTS) and Australasian-Society-for-Stem-Cell-Research (ASSCR), Sydney Australia, May 24-26, 2017. WILEY.

Little, Melissa H. (2017). Directing stem cells to kidney: From development to regeneration. 18th International Congress of Developmental Biology, Singapore, Jun 18-22, 2017. AMSTERDAM: ELSEVIER SCIENCE BV. doi: 10.1016/j.mod.2017.04.557

Lawlor, Kynan, Combes, Alexander and Little, Melissa H. (2017). Motile nephron progenitors can exit and re-enter the niche over time. 18th International Congress of Developmental Biology, Singapore, Jun 18-22, 2017. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.mod.2017.04.163

Walton, S. L., Singh, R. R., Bielefeldt-Ohmann, H., Li, J., Paravicini, T. M., Little, M. H. and Moritz, K. M. (2017). Prenatal Hypoxia and a Postnatal High Salt Diet Predisposes Mouse Offspring to Cardiovascular and Renal Impairments in Adulthood. 38th Annual Scientific Meeting of the High Blood Pressure Research Council of Australia, Hobart, Australia, 7-10 December 2016. Philadelphia, PA, United States: Lippincott Williams & Wilkins.

Combes, Alexander, Lefevre, James, Short, Kieran, Ju, Adler, Georgas, Kylie, Lamberton, Timothy, Cairncross, Oliver, Rumballe, Bree, McMahon, Andrew, Little, Melissa, Hamilton, Nicholas and Smyth, Ian (2017). An integrated cell, tissue and whole organ profile of kidney morphogenesis. 18th International Congress of Developmental Biology, Singapore, 18-22 June 2017. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.mod.2017.04.432

Little, M. H. (2016). Generating a kidney from human pluripotent stem cells: where to from here?. Conference on Changing the Face of Modern Medicine - Stem Cells and Gene Therapy, Florence, Italy, Oct 18-21, 2016. New Rochelle, United States: Mary Ann Liebert. doi: 10.1089/hum.2016.29035.abstracts

Mallett, A., Patel, C., Crawford, J., Alexander, S., Bennetts, B., Mccarthy, H., Quinlan, C., Maier, B., Er, P., Takasato, M., Healy, H., Smyth, I, Little, M. and Simons, C. (2016). Massively Parallel Sequencing (Mps) and Functional Genomics Can Achieve Genetic Diagnosis in Unresolved Cases of Genetic Renal Disease (Grd). The 15th Asian Pacific Congress of Nephrology (APCN) and 52nd ANZSN ASM, Perth, Western Australia, 17–21 September 2016. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia.

Li, Joan, Guo, Jinjin, McMahon, Jill A., McMahon, Andrew P. and Little, Melissa (2015). Preferential proliferation in response to injury by an interstitial-derived collecting duct subpopulation. American Society of Nephrology Annual Conference, San Diego, CA, United States, 3 - 8 November 2015.

Titmarsh, D., Glass, N., Hudson, J., Hidalgo, A., Porrello, E., Little, M., Wolvetang, E. and Cooper-White, J. (2015). Multiplexed Microbioreactor Arrays for Rapid Optimisation of Pluripotent Stem Cell Maintenance and Differentiation. 4th TERMIS World Congress, Boston Ma, Sep 08-11, 2015. NEW ROCHELLE: MARY ANN LIEBERT, INC.

Vanslambrouck, J. M., Woodard, L. E., Suhaimi, N., Wilson, M. H. and Little, M. H. (2015). The generation of a transposon-mediated system for direct transcriptional reprogramming to nephron progenitors. Ninth Australasian Gene and Cell Therapy Society Meeting, Parkville, Australia, April 29 – May 1 2015. Hoboken, United States: John Wiley & Sons. doi: 10.1002/jgm.2834

Little, M. H., Vanslambrouck, J. M., Takasato, M., Li, J., Suhaimi, N., Er, P. X. and Chiu, H. (2015). Transcriptional reprogramming and directed diffenrentiation of pluripotent stem cells: Alternative options for regenerating kidney. Ninth Australasian Gene and Cell Therapy Society Meeting, Parkville, Victoria, Australia, April 29 – May 1 2015. Hoboken, United States: John Wiley & Sons. doi: 10.1002/jgm.2834

Mallett, A., Hoer, S., John, G., Burke, J., Patel, C., Crawford, J., Hyland, V., Healy, H., Little, M., Simons, C., Connor, T. and Maxwell, P. (2015). The T616C Trna(Phe) mutation causes mitochondrially inherited tubulointerstitial kidney disease. 51st Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Canberra, Australia, 7-9 September 2015. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12543

Walton, S., Singh, R., Little, M. and Moritz, K. (2014). URINE-CONCENTRATING DEFECT ASSOCIATED WITH REDUCED NEPHRON NUMBER AND PROXIMAL AND DISTAL TUBULE ELONGATION IN MALE but not female OFFSPRING EXPOSED TO LATE-GESTATIONAL HYPOXIA. HOBOKEN: WILEY-BLACKWELL.

Walton, S. L., Singh, R. R., Paravicini, T. M., Wilkinson, L., Little, M. H. and Moritz, K. M. (2014). Chronic Mid-Late Gestational Hypoxia Leads to Hypertension in Male and Female Mouse Offspring. 35th Annual Scientific Meeting of the High Blood Pressure Research Council of Australia (HBPRCA) / 39th Annual Scientific Meeting of the Australian-Atherosclerosis-Society (AAS), Melbourne Australia, 05 - 07 December 2013. Philadelphia, PA United States: Lippincott Williams and Wilkins. doi: 10.1161/HYP.0000000000000010

Little, M. H., Takasato, M., Er, P., Becroft, M., Vanslambrouck, J., Stanley, E. and Elefanty, A. (2014). Directed Differentiation of Pluripotent Stem Cells to Form a Self-Organising Kidney. 14th Asian Pacific Congress of Nephrology, Tokyo, Japan, 14 - 17 May 2014. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12235

Mallett, A., Ho, G., Mccarthy, H., Fletcher, J., Mallawaarachchi, A., Little, M., Jueppner, H., Sawyer, A., Bennetts, B. and Alexander, S. (2014). Exomic Approaches to Diagnosis Amongst Australians with Genetic Renal Diseases. 50th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Melbourne, VIC Australia, 25-27 August 2014. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12302

Takasato, Minoru, Maier, Barbara and Little, Melissa H. (2013). Recreating kidney progenitors from pluripotent cells. Heidelberg, Germany: Springer. doi: 10.1007/s00467-013-2592-7

Phua, Y. L., Martel, N., Gilbert, T., Wilkinson, L. and Little, M. (2013). Loss of crim1 results in renal papillary hypoplasia via perturbations to Wnt/beta-catenin signalling. 49th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Brisbane, QLD Australia, 9-11 September 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12121

Wilkinson, L., Neal, C., Ju, A., Singh, R., Rumballe, B., Li, J., Moritz, K. and Little, M. (2013). Intrauterine Hypoxia Impairs Kidney Development Via Disruption to B-Catenin Activity. 49th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Brisbane, QLD Australia, 9-11 September 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12121

Takasato, M., Becroft, M., Er, P., Vanslambrouck, J., Stanley, E., Elefanty, A. and Little, M. (2013). Directing the Differentiation of Human Es Cells Towards a Renal Fate. 49th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Brisbane, QLD Australia, 9-11 September 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12121

Combes, A., Short, K., Lefevre, J., Ju, A., Georgas, K., Rumballe, B., Mcmahon, A., Hamilton, N., Smyth, I. and Little, M. (2013). An Integrated Cell, Tissue and Whole Organ Profile of Kidney Morphogenesis. 49th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Brisbane Australia, 9-11 September 2013. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12121

Li, J., Ariunbold, U., Mohammed-Suhaimi, N., Sunn, N. and Little, M. (2013). Selective Epithelial Potential of a Renal Mesenchymal Stem Cell-Like Population Derived From Mature Collecting Duct Epithelium. 49th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Brisbane, QLD Australia, 9-11 September 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12121

Wilkinson, L. J., Neal, C., Aroney, S., Pennisi, D. J. and Little, M. H. (2012). Podocyte Specific Deletion of Crim1 Leads to Glomerular Filtration Barrier Defects. 48th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Auckland, New Zealand, 27-29 August 2012. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1797.2012.01631.x

Wilkinson, L. J., Chiu, H., Ju, A., Rumballe, B., Georgas, K., Moritz, K. M. and Little, M. H. (2011). Hypoxic conditions during kidney development disrupt nephron formation. ANZSN 2011: 47th Annual Scientific Meeting Australian and New Zealand Society of Nephrology, Adelaide, SA, Australia, 17-21 September 2011. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1797.2011.01491.x

Kurniawan, Nyoman D., Wilkinson, Lorine J. and Little, Melissa H. (2010). In vivo MRI studies of Crim1 mutant mice: a model of abnormal renal vascular disease. World Molecular Imaging Conference, Kyoto , Japan, 8-11 September 2010.

Pennisi, David J., Chiu, Han S., Vinay, K. S., Wilkinson, Lorine, Zhang, Pumin and Little, Melissa H. (2010). Mice null for Crim1 display altered BMP/TGF beta signaling, defects in multiple organ systems and die in utero with severe cardiovascular defects. 69th Annual Meeting of the Society-for-Developmental-Biology/Japanese-Society-of-Developmental-Biologists, Albuquerque NM, AUG 05-09, 2010. SAN DIEGO: ACADEMIC PRESS INC ELSEVIER SCIENCE. doi: 10.1016/j.ydbio.2010.05.270

Jones, C. V., Little, M. H., Hume, D. A. and Ricardo, Sharon D. (2008). Colony Stimulating Factor (Csf)-1 in Postnatal Nephrogenesis and Organ Growth. HOBOKEN: WILEY-BLACKWELL.

Ricardo, S., Cochrane, A., Wang, L, Verghese, E, Kett, M., Little, M. and Deane, J. (2007). Endogenous renal repair following reversal of ureteral obstruction (Conference Abstract). 14th Congress of the International Pediatric Nephrology Association (IPNA), Budapest, Hungary, 31 August - 4 September 2007. New York, USA: Springer. doi: 10.1007/s00467-007-0558-3

Jones, C. V., Little, M. H., Hume, D. A. and Ricardo, S. D. (2007). Colony Stimulating Factor (Csf)-1 Promotes Nephrogenesis and Postnatal Growth in Newborn Mice. HOBOKEN: WILEY-BLACKWELL.

Ricardo, S. D., Alikhan, M. A., Campanale, N. V., Hume, D. A. and Little, M. H. (2007). Colony Stimulating Factor Reverses Established Renal Injury in An Acute Ischemic Mouse Model. HOBOKEN: WILEY-BLACKWELL.

Armstrong, S. R., Campbell, G. R., Campbell, J. H. and Little, M. H. (2006). Establishment of metanephros transplantation in mice highlights contributions by both nephrectomy and pregnancy to developmental progression. 7th Samuel A Latt Conference on Stem Cells in the Age of Fluorescence Technology, Gold Coast, Queensland, 6-9 November 2005. Hoboken, NJ., U.S.A.: Wiley-Liss. doi: 10.1002/cyto.a.20264

Challen, G. A., Bertoncello, I., Ricardo, S. D. and Little, M. H. (2006). Investigating the potential of murine kidney side population cells to act as functional renal stem cells (Conference Abstract). 7th Samuel A Latt Conference on Stem Cells in the Age of Fluorescence Technology, Gold Coast, Queensland, Australia, 6-9 Nov, 2005. Hoboken: Wiley-Liss. doi: 10.1002/cyto.a.20264

Pennisi, D., Wilkinson, L., Kolle, G., Gillinder, K. and Little, M. (2005). A hypomorphic mutant of Crim1 reveals a requirement on Crim1 for proper development. AMSTERDAM: ELSEVIER SCIENCE BV.

Patek, Charles E., Little, Melissa H., Fleming, Stewart, Miles, Colin, Charlieu, Jean-Paul, Clarke, Alan R., Miyagawa, Kiyoshi, Christie, Sheila, Doig, Jennifer, Harrison, David J., Porteous, David J., Brookes, Anthony J., Hooper, Martin L. and Hastie, Nicholas D. (1999). A zinc finger truncation of murine WT1 results in the characteristic urogenital abnormalities of Denys-Drash syndrome. doi: 10.1073/pnas.96.6.2931

Honorary Professor Melissa Little

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Book Chapters

Journal Articles

Conference Papers