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  • Research Visitor
    Institute for Molecular Bioscience
  • Medical Student
  • Smith Group

      Group Leader

    Dr Kelly Smith

    Group Leader, Genomics of Development and Disease Division
    Co-Director
    Centre for Cardiac and Vascular Biology
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    Highlights

    Dr Kelly Smith is a developmental biologist. She studies how the heart forms in embryo from a few cells of undetermined identity to a 3-dimensional beating organ. During her PhD, she was in the place where surgeons performed Australia’s first split liver transplant, trying to get more out of the organs that they had, and she thought ‘we should be making these.' Given the vital role the heart plays in supporting life, she has focussed her research to try and understand this particular organ.

    Dr Smith was involved in the largest forward genetic screen in Australia. Using Zebrafish, the study screened over 400 families of fish and found 30 different genes, nine of which were new. Through this study, she identified a gene responsible for heart arrhythmia and a protein called Tmem2 that degrades the extracellular matrix. Dr Smith had discovered the gene in her post-doctoral research, but the large-scale forward screen helped to describe its role in our body.

    During her post-doctoral research, Dr Smith also found a mutation responsible for a congenital condition called ‘atrial septal defect’ where blood flows between the chambers.

    Dr Smith conducts her research using Zebrafish. She creates a fish version of a patient (an avatar) with a particular gene mutation and monitors what is happening within the embryo.

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      Researchers

      Students

    Mr Sam Capon

    Higher degree by research (PhD) student
    Institute for Molecular Bioscience
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    Miss Jessica De Angelis

    Higher degree by research (PhD) student
    Institute for Molecular Bioscience
    Researcher profile is public: 
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    Miss Vanessa Raileanu

    Higher degree by research (PhD) student
    Institute for Molecular Bioscience
    Researcher profile is public: 
    0
    Supervisor: 

    Miss Daniela Grassini

    Higher degree by research (PhD) student
    Institute for Molecular Bioscience
    Researcher profile is public: 
    0
    Supervisor: 
  • Wang Group Team

    Group Leader

    Dr Conan Wang

    ARC Future Fellow and Group Leader
    Institute for Molecular Bioscience
    Researcher profile is public: 
    1
    Supervisor: 
    Researcher biography: 

    I lead the Technology-Driven Drug Discovery (Tech3D) Group at the Institute for Molecular Bioscience, UQ. We believe that the key to solving some of our world's biggest challenges, whether that be in medicine or agriculture, relies on the ability to precision engineer molecules at will. My group harnesses three technological pillars to engineer peptides and proteins, which are computational biology, molecular libraries, and nanotechnology. We aspire to design better drugs, creating next generation biotechnological agents that have real impact. These could be new cancer drugs that harness the body's immune system or new insecticides that are environmentally friendly. In these pursuits, we value advancement, fun, balance, respect, fairness, and integrity.

    I have been involved in peptide and protein research for over two decades, and am highly experienced in bioinformatics, chemistry, structural characterization, biophysics, and biochemistry. I trained with experts in peptide and protein characterization: an Honours project with Professor Garry King at the University of New South Wales, Sydney, Australia (2004), an APA scholarship with Professor David Craik at the University of Queensland Institute for Molecular Bioscience, Brisbane, Australia (2005-2009) and a NHMRC fellowship with Professor Mingjie Zhang at the Hong Kong University of Science and Technology, Hong Kong, China (2009-2011) and A/Professor Andreas Hofmann at Griffith University Eskitis Institute, Brisbane, Australia (2011-2012). I returned to the University of Queensland in 2012 to join an industry partnership funded by an ARC linkage grant. I currently hold an ARC Future Fellowship and am responsible for a team of research officers, assistants and postgraduate students.

    My research output has been recognised by >30 prizes and awards for leadership, research translation and fundamental research excellence, as well as numerous invitations to speak at academic and pharmaceutical conferences. I have over 100 publications and have been cited by researchers from across the world.

    Researchers

    Ms Jing Xie

    Postdoctoral Research Fellow
    Institute for Molecular Bioscience
    Researcher profile is public: 
    1
    Supervisor: 

    Mr Biswajit Biswas

    Researcher profile is public: 
    0
    Supervisor: 

    Mr Hiron Saraj Devnath

    Researcher profile is public: 
    0
    Supervisor: 

    Mr Gene Jiang

    Research Staff
    Institute for Molecular Bioscience
    Researcher profile is public: 
    1
    Supervisor: 

    Students

    Lavina Hanna

    Researcher profile is public: 
    1
    Supervisor: 

    Zhengyu Yuan

    Researcher profile is public: 
    1
    Supervisor: 

    Kevin Zhang

    Researcher profile is public: 
    1
    Supervisor: 
  • Honorary Fellow
    Institute for Molecular Bioscience
  • Visiting Academic
    Institute for Molecular Bioscience
  • PhD student
    Institute for Molecular Bioscience

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The Edge: Genetics

People have known for thousands of years that parents pass traits to their children, but it is only relatively recently that our technology has caught up to our curiosity, enabling us to delve into the mystery of how this inheritance occurs, and the implications for predicting, preventing and treating disease.

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