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Risk of depression and heart disease linked in women
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- Research VisitorInstitute for Molecular Bioscience
- Medical Student
Smith Group
Group Leader
Dr Kelly Smith
Group Leader, Genomics of Development and Disease DivisionCo-DirectorCentre for Cardiac and Vascular BiologyResearcher profile is public:0Supervisor:Body:Highlights
Dr Kelly Smith is a developmental biologist. She studies how the heart forms in embryo from a few cells of undetermined identity to a 3-dimensional beating organ. During her PhD, she was in the place where surgeons performed Australia’s first split liver transplant, trying to get more out of the organs that they had, and she thought ‘we should be making these.' Given the vital role the heart plays in supporting life, she has focussed her research to try and understand this particular organ.
Dr Smith was involved in the largest forward genetic screen in Australia. Using Zebrafish, the study screened over 400 families of fish and found 30 different genes, nine of which were new. Through this study, she identified a gene responsible for heart arrhythmia and a protein called Tmem2 that degrades the extracellular matrix. Dr Smith had discovered the gene in her post-doctoral research, but the large-scale forward screen helped to describe its role in our body.
During her post-doctoral research, Dr Smith also found a mutation responsible for a congenital condition called ‘atrial septal defect’ where blood flows between the chambers.
Dr Smith conducts her research using Zebrafish. She creates a fish version of a patient (an avatar) with a particular gene mutation and monitors what is happening within the embryo.
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Mr Sam Capon
Higher degree by research (PhD) studentInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:Miss Jessica De Angelis
Higher degree by research (PhD) studentInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:Miss Vanessa Raileanu
Higher degree by research (PhD) studentInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:Miss Daniela Grassini
Higher degree by research (PhD) studentInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:Wang Group Team
Group Leader
Dr Conan Wang
ARC Future Fellow and Group LeaderInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Researcher biography:I lead the Technology-Driven Drug Discovery (Tech3D) Group at the Institute for Molecular Bioscience, UQ. We believe that the key to solving some of our world's biggest challenges, whether that be in medicine or agriculture, relies on the ability to precision engineer molecules at will. My group harnesses three technological pillars to engineer peptides and proteins, which are computational biology, molecular libraries, and nanotechnology. We aspire to design better drugs, creating next generation biotechnological agents that have real impact. These could be new cancer drugs that harness the body's immune system or new insecticides that are environmentally friendly. In these pursuits, we value advancement, fun, balance, respect, fairness, and integrity.
I have been involved in peptide and protein research for over two decades, and am highly experienced in bioinformatics, chemistry, structural characterization, biophysics, and biochemistry. I trained with experts in peptide and protein characterization: an Honours project with Professor Garry King at the University of New South Wales, Sydney, Australia (2004), an APA scholarship with Professor David Craik at the University of Queensland Institute for Molecular Bioscience, Brisbane, Australia (2005-2009) and a NHMRC fellowship with Professor Mingjie Zhang at the Hong Kong University of Science and Technology, Hong Kong, China (2009-2011) and A/Professor Andreas Hofmann at Griffith University Eskitis Institute, Brisbane, Australia (2011-2012). I returned to the University of Queensland in 2012 to join an industry partnership funded by an ARC linkage grant. I currently hold an ARC Future Fellowship and am responsible for a team of research officers, assistants and postgraduate students.
My research output has been recognised by >30 prizes and awards for leadership, research translation and fundamental research excellence, as well as numerous invitations to speak at academic and pharmaceutical conferences. I have over 100 publications and have been cited by researchers from across the world.
Body:Researchers
Ms Jing Xie
Postdoctoral Research FellowInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Mr Biswajit Biswas
Researcher profile is public:0Supervisor:Mr Hiron Saraj Devnath
Researcher profile is public:0Supervisor:Mr Gene Jiang
Research StaffInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Students
Lavina Hanna
Researcher profile is public:1Supervisor:Zhengyu Yuan
Researcher profile is public:1Supervisor:Kevin Zhang
Researcher profile is public:1Supervisor:- Honorary FellowInstitute for Molecular Bioscience
- Visiting AcademicInstitute for Molecular Bioscience
- PhD studentInstitute for Molecular Bioscience
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The Edge: Genetics
People have known for thousands of years that parents pass traits to their children, but it is only relatively recently that our technology has caught up to our curiosity, enabling us to delve into the mystery of how this inheritance occurs, and the implications for predicting, preventing and treating disease.
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