Chemistry and human therapeutics

Studying the molecular mechanisms of life, ageing, disease and death

The Fairlie Group work at the interface of chemistry and biology to better understand the molecular mechanisms of life, ageing, disease and death.

The chemists within the group study medicinal chemistry, organic synthesis, and computer-aided drug design; use nuclear magnetic resonance (NMR) spectroscopy to investigate the structure and dynamics of proteins; and learn how small molecules interact with other small molecules, proteins, RNA and DNA.

They discover new chemical structures, reactions and mechanisms; enzyme inhibitors, agonists and antagonists; and molecules that mimic the structures and functions of bioactive protein surfaces.

The biologists within the group use these novel compounds to explain the functions of human proteins and cells, and apply them to treat animal models of human diseases.

They study mechanisms of protein and cell activation, biological processes, disease development and drug action.

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    Prof David Fairlie

    Professor David Fairlie

    Head, Chemistry and Structural Biology Division

    Investigator, Centre for Inflammation and Disease Research

    Investigator, Centre for Pain Research

      +61 7 3346 2989  
      d.fairlie@imb.uq.edu.au
      IMB Researcher Profile
      Centre for Inflammation and Disease Research


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      Group Leader

    • Professor David Fairlie

      Division Head & Group Leader, Chemistry and Structural Biology Division
      NHMRC Snr Principal Research Fellow
      Institute for Molecular Bioscience

      Researchers

      Students

    • Mr Yuanzhao Cao

      Higher degree by research (PhD) student
      Institute for Molecular Bioscience
    • Mr Darren Do

      Higher degree by research (PhD) student
      Institute for Molecular Bioscience
    • Mr Lilong Dong

      Higher degree by research (PhD) student
      Institute for Molecular Bioscience
    • Ms Yuhong Jiang

      Higher degree by research (PhD) student
      Institute for Molecular Bioscience
    • Miss Geraldine Ler

      Higher degree by research (PhD) student
      Institute for Molecular Bioscience
    • Ms Eunice Poon

      Higher degree by research (PhD) student
      Institute for Molecular Bioscience
    • Ms Jiahui Tng

      Higher degree by research (PhD) student
      Institute for Molecular Bioscience
    • Miss Peiqi Wang

      Higher degree by research (PhD) student
      Institute for Molecular Bioscience
    • Mr Chongyang Wu

      Higher degree by research (PhD) student
      Institute for Molecular Bioscience
    • Mr Justin Mitchell

      Higher degree by research (PhD) student
      Institute for Molecular Bioscience
    • Miss Jessica Rowley

      Higher degree by research (PhD) student
      Institute for Molecular Bioscience
    • Ms Maddison McLaughlin

      Higher degree by research (honours) student
      Institute for Molecular Bioscience

      Support staff