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- Adjunct Associate ProfessorInstitute for Molecular Bioscience
- PhD studentInstitute for Molecular Bioscience
- PhD student & Casual Senior Research Assistant (Biologist)Institute for Molecular Bioscience
- Senior Research FellowInstitute for Molecular Bioscience
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Vetter Group
Group Leader
Professor Irina Vetter
NHMRC Leadership Fellow - Group LeaderInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Researcher biography:I am an NHMRC Leadership Fellow with joint apointments at the Institute for Molecular Bioscience (IMB) and School of Pharmacy, UQ. My research interests lie in the fields of peripheral pain mechanisms, target identification and analgesic drug discovery. I investigate the contribution of ion channels to sensory neuronal physiology using highly subtype-selective toxins isolated from venomous animals with the aim to develop novel analgesics with improved efficacy and tolerability.
Body:Highlights
Associate Professor Irina Vetter has a strong background in neuropharmacology, pain models, toxinology and high-throughput screening. Currently her primary research interests lie in the fields of peripheral pain mechanisms, target identification, biodiscovery of venom peptide ion channel modulators and analgesic drug discovery.
Associate Professor Vetter has always been fascinated by how we perceive the world around us, in particular, the role of sensory neurons in the body. Sensory neurons are an intricate network of nerve cells that convert external stimuli from the environment into messages within the body, like pain. Her research is demystifying the different pathways that contribute to pain in various disease states. She is using biomedical research and pharmacology to develop pain treatments from venoms and toxins.
Associate Professor Vetter is an ARC Future Fellow and Deputy Director of the Centre for Pain Research at The University of Queensland. She is a registered pharmacist and has worked in hospital as well as community pharmacy. She obtained her PhD in 2007 from the School of Pharmacy, and conducted postdoctoral studies as an NHMRC postdoctoral fellow under Prof Geoffrey Goodhill at the Queensland Brain Institute and under Prof Richard J Lewis at the Institute for Molecular Bioscience in the areas of axon guidance and venom peptide pharmacology
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Researchers
Dr Jennifer Deuis
ARC DECRAInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Researcher biography:My main research focus has been applying venom peptide pharmacology to pain pathway characterisation. This approach has led to the identification of novel pain mechanisms underlying the development of chemotherapy-induced pain, ciguatera, and burn-induced pain. In an addition, I have identified and characterised over 20 novel bioactive peptides, which includes a novel class of Nav1.7 inhibitors that is currently undergoing pre-clinical development as analgesics, and a novel class of stinging nettle toxins that act on a previously unidentified Nav1.7 interacting protein named TMEM233.
Dr Angelo Keramidas
Senior Research FellowInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Researcher biography:I am interested in ion channels in health and disease. Improved technologies for genetic screening is revealing an expanding catalogue of genetic variants to ion channels that give rise neurological disorders, such as epilespy syndromes, autism spectrum disorder and other neurodevelopmental disorders. My main research focus is on neurotransmitter-activated receptor ion channels that are found at neuronal synapses. These include GABA-A, glycine and glutamate (NMDA) receptors. I also work on other ion channesl such as voltage-gated sodium channels and synaptic receptors expressed in invertebrate nervous systems.
I am an expert at recording single ion channel, synaptic and conventional whole-cell currents for functional and pharmacological analyisis.
I collaborate with biophysicists, molecular biologists, geneticists, electrophysiologists and clinicians that specialise in genetic neurological disorders. I have active projects in collaboration with research groups in Australia, USA and Europe.
Ms Asa Andersson
Research AssistantInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:Dr Hana Starobova
Higher degree by research (PhD) student & NHMRC Emerging Leadership FellowInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Researcher biography:Dr Hana Starobova is a pharmacist and NHMRC research fellow at the Sensory Neuropharmacology Group at the University of Queensland (UQ). She works under the mentorship of Prof. Vetter, and as an early career researcher, she is working toward an independent research career as a group leader. She obtained her PhD in 2020 from the Institute for Molecular Bioscience, UQ, and continued here to conduct studies as a Children Hospital Foundation Fellow (2021-2023) in the areas of cancer therapy-induced adverse and late effects with the main focus on neuropathies. Over the past four years, she has developed a research program focusing on the understanding of cancer therapy-induced adverse and late effects with a special interest in children, and established innovative transcriptomic and microscopy pipelines, in vitro assays, adult and juvenile models of adverse and late effects following mono- and combination chemotherapy and radiotherapy, assays for the assessment of adverse effects including cognition and neuropathies, as well as cancer models. Knowledge impact arising from her research program has been disseminated in 18 peer-reviewed publications, having together attracted >1,100 citations (h-index 15, i10-index 18, Google Scholar, May 2024).
Mr Theo Crawford
Visiting ResearcherInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:Dr Vanessa Schendel
Postdoctoral Research FellowInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Mr Ben Cristofori-Armstrong
Higher degree by research (PhD) studentResearcher profile is public:0Supervisor:Ms Thi Ngoc Hue Tran
Researcher profile is public:1Supervisor:Students
Ms Wanlin Chen
Researcher profile is public:0Supervisor:Ms Naiqi Shi
Researcher profile is public:0Supervisor:Mr Ammar Alshammari
PhD studentInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Miss Priyaa Purushotham Vasan
Researcher profile is public:1Supervisor:Ms Svetlana Shatunova
PhD studentInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Miss Nicolette Tay
PhD studentInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Ms Ashvriya Thapa
PhD studentInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Ms Lucinda Walker
Global Challenges ScholarInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:- PhD studentInstitute for Molecular Bioscience
- Our research aims to understand the molecular mechanisms behind pain
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