Protein structure in drug and insecticide design

Creating the perfect drug

Plants and animals make mini-proteins called peptides. They are very potent and very specific in what they do, which makes them ideal candidates for drug development. They would be very effective and have minimal side effects, but for one problem – the body thinks they are food.

Peptides produced within our bodies are finely regulated, but those taken by mouth are ripe for destruction, since that is the normal job of our digestive system.

“Our bodies can’t tell the difference between the peptides in say a steak and an insulin tablet, if such a thing existed. Our bodies have evolved to break peptides down quickly to form amino acids ,” said Group Leader Professor David Craik.

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Prof David Craik

Professor David Craik

Group Leader, Chemistry and Structural Biology Division

Director, Clive and Vera Ramaciotti Facility for Producing Pharmaceuticals in Plants

Investigator, Centre for Pain Research

  +61 7 3346 2019  
  d.craik@imb.uq.edu.au
  IMB Researcher Profile
  Centre for Pain Research
  Clive and Vera Ramaciotti Facility for Producing Pharmaceuticals in Plants


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  Group Leader

  • Professor David Craik

    Group Leader, Chemistry and Structural Biology Division
    ARC Laureate Fellow
    Institute for Molecular Bioscience

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