I am a basic science researcher trained in molecular and cell biology, with expertise in transdisciplinary research. My primary focus is investigating the circadian aspects of (patho-) physiology, specifically in relation to the liver. I am particularly interested in understanding how circadian, endocrine, and metabolic pathways work together to maintain homeostasis, as well as how disruptions in these pathways can contribute to pathological conditions.

Following the completion of my PhD at Heidelberg University in Germany in 2013, I pursued post-doctoral studies as a Marie-Curie Fellow at Birmingham University (UK) and École Polytechnique Fédérale de Lausanne (Switzerland). During this time, I utilized omics-approaches to elucidate the metabolic changes caused by impaired mitochondrial glucocorticoid biosynthesis and adrenal insufficiency. Additionally, I investigated the relationship between mitochondrial function and stress-induced depression. In order to understand the molecular mechanisms underlying rhythmic expression of metabolic genes, I also developed tools that facilitate the study of how circadian clock components and glucocorticoids cooperatively drive these processes.

In 2019, I have joined the Physiology of Circadian Rhythms laboratory at the Institute of Molecular Bioscience, University of Queensland, to investigate the role of the circadian clock and chronodisruption in metabolism and liver disease.

Critical Care Medicine focuses on supporting patients, often with one or multiple organ failures. Based at the largest Australian cardiac hospital, our research investigates better ways to support patients with heart and/or lung failure. We explore technological, pharmacological and engineering advances that could help our patients to live longer and better. Our group is world-renowned for clinically relevant large animal models, including heart failure, respiratory failure (ARDS), heart transplantation, sepsis, cardiogenic shock, and more. All our studies use hospital-grade equipment and follow the same clinical guideline to maximise translation. We actively take on honours, MPhil and PhD students from multi-disciplinary backgrounds (science, engineering, medicine, allied health), with a successful track record in supporting our students to secure their own grants and funding. Students are expected to contribute to other studies of the group. For more information about the group, please visit ccrg.org.au, and email if you are interested to join us.

Research interests in Artificial Heart and Lung therapies.

Charted Engineering (Biomedical) with Engineers Australia and BPEQ. Industry experience in nonclinical device testing and regulatory submissions of total artificial heart.

Engineering Lead at Innovative Cardiovascular Engineering and Technology Laboratory (ICETLab), Critical Care Research Group, The Prince Charles Hospital