IMB's latest news, explainers and more

 


Electric caterpillar sparks new venom discoveries

Read more

Get the latest research to your inbox

Subscribe
 

  • What food can you eat to increase good bacteria in the gut?
  • 7 Aug 2022
    We are delighted to invite you to a very special event at IMB on the St Lucia campus. We are throwing our doors open for the day on Sunday 7 August so you can come and learn about science and IMB. The UQ campus will be buzzing because it’s Open Day so why not come and see what’s on offer at IMB?


  • Our vision is to transform global industries with solar-driven biotechnologies that secure planetary sustainability and resilience.
  • Higher degree by research (PhD) student
    Institute for Molecular Bioscience
  • Adjunct and Honorary

    Ms Kylie Ahern

    Industry Fellow
    Researcher profile is public: 
    0
    Supervisor: 

    Mr Robert Christiansen

    Adjunct Professor
    Institute for Molecular Bioscience
    Researcher profile is public: 
    1
    Supervisor: 

    Adjunct Professor Michael Holmes

    Adjunct Professor
    Institute for Molecular Bioscience
    Researcher profile is public: 
    0
    Supervisor: 

    Adjunct Professor Norelle Daly

    Adjunct Professor
    Institute for Molecular Bioscience
    Researcher profile is public: 
    0
    Supervisor: 

    Honorary Professor Michael Goddard

    Honorary Professor
    Institute for Molecular Bioscience
    Researcher profile is public: 
    0
    Supervisor: 

    Professor Wanjin Hong

    Honorary Professor
    Institute for Molecular Bioscience
    Researcher profile is public: 
    0
    Supervisor: 

    Honorary Professor Melissa Little

    Honorary Professor
    Institute for Molecular Bioscience
    Researcher profile is public: 
    0
    Supervisor: 

    Emeritus Professor Jenny Martin

    Emeritus Professor
    Institute for Molecular Bioscience
    Researcher profile is public: 
    0
    Supervisor: 

    Honorary Professor John Mattick

    Honorary Professor
    Institute for Molecular Bioscience
    Researcher profile is public: 
    0
    Supervisor: 

    Honorary Professor Luke O'Neill

    Honorary Professor
    Institute for Molecular Bioscience
    Researcher profile is public: 
    0
    Supervisor: 

    Honorary Professor Vicki Sara

    Institute for Molecular Bioscience
    Researcher profile is public: 
    0
    Supervisor: 
    Body: 

    Professor Vicki Sara was elected Chancellor of the University of Technology Sydney in 2004. Professor Sara is a Fellow of the Australian Academy of Science and the Australian Academy of Technological Sciences and Engineering.

    Professor Sara’s previous appointments include Chief Executive Officer of the Australian Research Council from 2001-2004 and Chair of the Council and a member of the Prime Minister’s Science Engineering and Innovation Council (PMSEIC), and the CSIRO Board  from 1997-2001.  Professor Sara was also a member of the Advisory Board of the Rio Tinto Foundation for a Sustainable Minerals Industry from 2002-2007, Consul General for Sweden in Sydney from 2006-2007, andwas appointed Vice-Chair of the OECD’s Global Science Forum in 1999 and member of the Advisory Board of the APEC R&D Leaders’ Forum in 2002.  She was Director of the Australian Centre for Plant Functional Genomics from 2004-2009, the Australian Institute  of Commercialisation  2007- 2010, Chair of the Board of the Australian Stem Cell Centre from 2005-2008, Chair of the Advisory Board of the Centre for Quantum Computation and Communication Technology 2011-2012, and Chair NSW Panel Sir John Monash Scholarship 2011-2013.  Professor Sara was elected Convenor of the University Chancellors Council 2006-2008 and 2011-2012.

    Professor Sara returned to Australia in 1993 following a research career at the Karolinska Institute in Stockholm.

    She was awarded the Rolf Luft medal in 1993 for excellence in endocrine research by the Karolinska Institute, and also received the Sir John Eccles Award from the NH&MRC in 1994.  She was appointed as foreign Professor of Karolinska Institute in 1995.  She was awarded the Centenary Medal in 2003, and was awarded an Honorary Doctor of Science by the University of Southern Queensland in 2004, the Victoria University in 2005, the University of Technology Sydney in 2009, and the University of Sydney in 2016. She was awarded an Honorary Doctor of the University, Queensland University of Technology in 2006.

    Professor Sara was appointed an Officer of the Order of Australia (AO) for distinguished service to science and higher education in 2010

    Honorary Professor Ben Hogan

    Honorary Professor
    Institute for Molecular Bioscience
    Researcher profile is public: 
    0
    Supervisor: 
  • Research Officer
    Institute for Molecular Bioscience
  • Coin Group

      Group Leader

    Dr Lachlan Coin

    Honorary Associate Professor
    Institute for Molecular Bioscience
    Researcher profile is public: 
    0
    Supervisor: 
    Body: 

    Highlights

    Professor Lachlan Coin is a mathematician with a research focus on developing genomics and bioinformatics tools in infectious disease and cancer. He was originally drawn by the rigour and intellectual challenge of pure mathematics but now uses his maths background as a toolkit for solving complex problems in analysing high throughput biological data.

    Professor Coin is best known for using approaches borrowed from machine learning, statistics and probability theory to interrogate genomic data.

    In particular, Professor Coin has focussed on using these approaches to uncover genomic deletions and amplifications and has identified changes that are associated with increased risk of obesity and diabetes.

    He has also developed approaches for finding minimal biomarker signatures associated with disease, and has applied these approaches to find biomarkers that distinguish bacterial from viral infection, and for the presence of active tuberculosis infection. He is also applying his methodology to develop a diagnostic tool for cancer from cell free DNA

    Ultimately, Professor Coin is motivated by making discoveries that are routinely used in clinical practice and to inform public policy to improve health outcomes.

    Professor Coin holds an Honorary Professor appointment with UQ, and is a Professor at the Doherty Institute at the University of Melbourne.

    Connect

    ResearcherIDScopusOrcid

     

      Researchers

    Mrs Tania Da Silva Duarte

    Postdoctoral Research Fellow
    Institute for Molecular Bioscience
    Researcher profile is public: 
    1
    Supervisor: 

    Dr Quan Nguyen

    Senior Research Fellow
    Institute for Molecular Bioscience
    Researcher profile is public: 
    1
    Supervisor: 
    Researcher biography: 

    Dr Quan Nguyen is a Group Leader at the Institute for Molecular Bioscience (IMB), The University of Queensland. He is leading the Genomics and Machine Learning (GML) lab to study neuroinflammation and cancer-immune cells at single-cell resolution and within spatial morphological tissue context. His research interest is about revealing gene and cell regulators that determine the states of the complex cancer and neuronal ecosystems. Particularly, he is interested in quantifying cellular diversity and the dynamics of cell-cell interactions within the tissues to find ways to improve cancer diagnosis or cell-type specific treatments or the immunoinflammation responses that cause neuronal disease.

    Using machine learning and genomic approaches, his group are integrating single-cell spatiotemporal sequencing data with tissue imaging data to find causal links between cellular genotypes, tissue microenvironment, and disease phenotypes. GML lab is also developing experimental technologies that enable large-scale profiling of spatial gene and protein expression (spatial omics) in a range of cancer tissues (focusing on brain and skin cancer) and in mouse brain and spinal cord.

    Dr Quan Nguyen completed a PhD in Bioengineering at the University of Queensland in 2013, postdoctoral training in Bioinformatics at RIKEN institute in Japan in 2015, a CSIRO Office of Chief Executive (OCE) Research Fellowship in 2016, an IMB Fellow in 2018, an Australian Research Council DECRA fellowship (2019-2021), and is currently a National Health and Medical Research Council leadership fellow (EL2). He has published in top-tier journals, including Cell, Cell Stem Cell, Nature Methods, Nature Protocols, Nature Communications, Genome Research, Genome Biology and a prize-winning paper in GigaScience. In the past three years, he has contributed to the development of x8 open-source software, x2 web applications, and x4 databases for analysis of single-cell data and spatial transcriptomics. He is looking for enthusiastic research students and research staff to join his group.

      Students

    Dr Son Nguyen

    Higher degree by research (PhD) student
    Institute for Molecular Bioscience
    Researcher profile is public: 
    0
    Supervisor: 

    Ms Miranda Pitt

    Higher degree by research (PhD) student
    Institute for Molecular Bioscience
    Researcher profile is public: 
    0
    Supervisor: 

    Mr Haojing Shao

    Higher degree by research (PhD) student
    Institute for Molecular Bioscience
    Researcher profile is public: 
    1
    Supervisor: 

    Mr Chenxi Zhou

    Higher degree by research (PhD) student
    Institute for Molecular Bioscience
    Researcher profile is public: 
    1
    Supervisor: 

    Mr Hyun Jae Lee

    Higher degree by research (PhD) student
    Institute for Molecular Bioscience
    Researcher profile is public: 
    1
    Supervisor: 

    Ms Janice Reid

    Honours student
    Institute for Molecular Bioscience
    Researcher profile is public: 
    1
    Supervisor: 

    Ms Dilys Li

    Honours student
    Institute for Molecular Bioscience
    Researcher profile is public: 
    1
    Supervisor: 

      Support staff

Pages

Strawberry DNA extraction activity

Extract and view DNA from a strawberry using common household ingredients.

Get started

 

The Edge: Infection

The latest research and discovery

We are tackling the problem of drug-resistant bacteria through developing new diagnostics and treatments, and by empowering the community with knowledge on how to fight back against the threat of superbugs.

 View the latest issue
 Download magazine

Subscribe to our newsletter

Get the latest research straight to your inbox. 
Stay up-to-date as we answer questions about hot topics, and share the latest news at IMB, Australia’s #1 research institute.

Subscribe

General enquiries

  +61 7 3346 2222
  imb@imb.uq.edu.au

Media enquiries

IMB fully supports UQ's Reconciliation Action Plan and is implementing actions within our institute.

Support us

Donate to research
100% of donations go to the cause