We are studying the structure of the cavin proteins (with Brett Collins, IMB). These elongated molecules form a unique striated coat on the surface of caveolae. By combining structural biology (X-ray crystallography, cryoelectron microscopy) with functional in vivo assays in genome edited zebrafish we are elucidating structure-function relationships of the cavin proteins.

Project members

Key contact

Professor Robert Parton

Division Head & Group Leader, Cell and Developmental Biology
Professorial Research Fellow - GL
Institute for Molecular Bioscience