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  • PhD student & Research Officer
    Institute for Molecular Bioscience
  • PhD Student
    Institute for Molecular Bioscience
  • Research Visitor
    Institute for Molecular Bioscience
  • PhD student
    Institute for Molecular Bioscience
  • SAGHA team

    Associate Professor Sonia Shah

    National Heart Foundation Future Leader Fellow
    National Heart Foundation Future Leader Fellow, Senior Principal Research Fellow –Group Leader
    Institute for Molecular Bioscience
    Researcher profile is public: 
    1
    Supervisor: 
    Researcher biography: 

    My group's research uses large-scale genomic data to address knowledge gaps in disease, with a particular focus on cardiovascular disease.

    Research programme

    1. Cardiovascular disease research using big-data and genomics: with the goal of improving prevention and treatment of cardiovascular disease. By focusing on underrepresented groups, including women, my research aims to also address inequity in cardiovascular outcomes. I am the lead of the South Asian Genes and Health in Australia (SAGHA) study, which aims to increase representation of Australian South Asians in cardiovascular and genomics research. See saghaus.org for further details.

    2. Drug genomics: I'm interested in using genomic approaches to predict drug effects, including identification of drug repurposing opportunities as well as identifying unknown adverse effects of medication.

    3. Liver transplant research: In this collaboration with the QLD Liver Transplant Unit, we are using genomics to understand the effect of normo-thermic perfusion (a new organ storage method) on liver function, with the long-term goal of improving our ability to predict transplant outcomes.

    Career summary: I was awarded my PhD from University College London (UK) in cardiovascular genetics. I began my post-doctoral fellowship under the mentorship of Prof Peter Visscher at the Queensland Brain Institute in 2013. Between 2016-2018, I was the lead analyst for the International Heart Failure Genetics Consortium (HERMES). In 2018, I was awarded an NHMRC Early Career Researcher Fellowship to investigate the relationship between cardiovascular and brain-related disorders using large-scale genetic and genomic data, under the mentorship of Prof Naomi Wray. I currently hold a National Heart Foundation Future Leader Fellowship.

    Recognition:

    2024 Australian Academy of Science Ruth Stephens Gani Medal for outstanding contribution to genetics research

    2023 1 of 5 global finalists for the Nature Inspiring Women in Science (Scientific Achievement Award)

    2023 Lifesciences QLD Rose-Anne Kelso Award

    2023: Named in Australia's Top 25 Women in Science by Newscorp

    2022 Queensland Young Tall Poppy Award

    2022 UQ Foundation Research Excellence Award

    2021/2022 Australian Superstar of STEM,

    2020 Genetic Society of Australasia Early Career Award

    2020 Women in Technology Rising Star Science Award

  • Sequencing facility

    Ms Angelika Christ

    UQ Sequencing Facility Manager
    Researcher profile is public: 
    0
    Supervisor: 
    Body: 

    Angelika Christ is Facility Manager of the IMB Sequencing Facility, where she leads a team of sequencing and bioinformatition specialists, producing high-quality sequencing libraries and next-generation sequencing data.

    Angelika and her team help find researchers the best approach to their sequencing projects — ranging from agriculture, to drug development and medical research — and ensure the best outcomes.

    Angelika has 13 years of commercial and research laboratory experience. She has worked in the field of next-generation sequencing since 2010 on various technology platforms and applications.

    Angelika holds a Dipl.-Ing (FH) (equivalent to masters degree) in Biochemistry from the Mannheim University of Applied Sciences in Germany and a brings experience in organic chemistry and peptide chemistry as well as cell culture and assay development to her work at the IMB Sequencing Facility.

    View Angelika's publications via PubMed

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The Edge: Genetics

People have known for thousands of years that parents pass traits to their children, but it is only relatively recently that our technology has caught up to our curiosity, enabling us to delve into the mystery of how this inheritance occurs, and the implications for predicting, preventing and treating disease.

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