The human genome contains 3 billion DNA base pairs that provide the blueprint of life. Diseases can be caused by changes to just one of these base pairs, or by complex interactions across the genome. IMB researchers are decoding the critical base changes that influence disease progress and cause variation in individuals, with the ultimate aim of making significant advances in understanding the genetics of disease and using this information to develop new diagnostics and treatment targets for a range of disease.
IMB resesearchers are investigating:
- endometriosis
- bacterial infection
- disorders of sex development
- postnatal depression
- motor neurone disease
- psychiatric disorders
- neurological disorder
- schizophrenia
- obesity