The structure of caveolae in situ

Caveolae are endocytic pits of the cell surface that have diverse roles in the cell, from lipid homeostasis to mechanoprotection and signal transduction. We aim to characterise the structure of caveolae at high resolution in the native state and understand how changes in substrate stiffness modulate caveolar organisation and structure. This project is a collaboration between the Parton Group (IMB, UQ) and the Collins Group (IMB, UQ).