Dr Huanwei Wang
Postdoctoral Research Fellow
Institute for Molecular Bioscience
Researcher biography
I joined the Institute for Molecular Bioscience (IMB) at the University of Queensland (UQ) in April/2017 as a Ph.D. student with Prof. Jian Yang and Dr. Allan McRa. In 2021, I continue to work at IMB/UQ as a Postdoctoral Research Fellow supervised with Dr. Loic Yengo and Prof. Peter Visscher. My current research project is to quantify the contribution of ultrarare genetic variants to human complex traits.
Journal Articles
Campos, Adrian I., Namba, Shinichi, Lin, Shu-Chin, Nam, Kisung, Sidorenko, Julia, Wang, Huanwei, Kamatani, Yoichiro, Wang, Ling-Hua, Lee, Seunggeun, Lin, Yen-Feng, Feng, Yen-Chen Anne, Okada, Yukinori, Visscher, Peter M., Yengo, Loic and The Biobank Japan Project (2023). Boosting the power of genome-wide association studies within and across ancestries by using polygenic scores. Nature Genetics, 55 (10), 1769-1776. doi: 10.1038/s41588-023-01500-0
Hemani, Gibran, Powell, Joseph E., Wang, Huanwei, Shakhbazov, Konstantin, Westra, Harm-Jan, Esko, Tonu, Henders, Anjali K., McRae, Allan F., Martin, Nicholas G., Metspalu, Andres, Franke, Lude, Montgomery, Grant W., Goddard, Michael E., Gibson, Greg, Yang, Jian and Visscher, Peter M. (2021). Phantom epistasis between unlinked loci. Nature, 596 (7871), E1-E3. doi: 10.1038/s41586-021-03765-z
Zeng, Jian, Xue, Angli, Jiang, Longda, Lloyd-Jones, Luke R., Wu, Yang, Wang, Huanwei, Zheng, Zhili, Yengo, Loic, Kemper, Kathryn E., Goddard, Michael E., Wray, Naomi R., Visscher, Peter M. and Yang, Jian (2021). Widespread signatures of natural selection across human complex traits and functional genomic categories. Nature Communications, 12 (1) 1164, 1-12. doi: 10.1038/s41467-021-21446-3
Wu, Yang, Qi, Ting, Wang, Huanwei, Zhang, Futao, Zheng, Zhili, Phillips-Cremins, Jennifer E., Deary, Ian J., McRae, Allan F., Wray, Naomi R., Zeng, Jian and Yang, Jian (2020). Promoter-anchored chromatin interactions predicted from genetic analysis of epigenomic data. Nature Communications, 11 (1) 2061, 1-12. doi: 10.1038/s41467-020-15587-0
Revez, Joana A., Lin, Tian, Qiao, Zhen, Xue, Angli, Holtz, Yan, Zhu, Zhihong, Zeng, Jian, Wang, Huanwei, Sidorenko, Julia, Kemper, Kathryn E., Vinkhuyzen, Anna A. E., Frater, Julanne, Eyles, Darryl, Burne, Thomas H. J., Mitchell, Brittany, Martin, Nicholas G., Zhu, Gu, Visscher, Peter M., Yang, Jian, Wray, Naomi R. and McGrath, John J. (2020). Genome-wide association study identifies 143 loci associated with 25 hydroxyvitamin D concentration. Nature Communications, 11 (1) 1647, 1-12. doi: 10.1038/s41467-020-15421-7
Lloyd-Jones, Luke R., Zeng, Jian, Sidorenko, Julia, Yengo, Loïc, Moser, Gerhard, Kemper, Kathryn E., Wang, Huanwei, Zheng, Zhili, Magi, Reedik, Esko, Tõnu, Metspalu, Andres, Wray, Naomi R., Goddard, Michael E., Yang, Jian and Visscher, Peter M. (2019). Improved polygenic prediction by Bayesian multiple regression on summary statistics. Nature Communications, 10 (1) 5086, 1-10. doi: 10.1038/s41467-019-12653-0
Wang, Huanwei, Zhang, Futao, Zeng, Jian, Wu, Yang, Kemper, Kathryn E., Xue, Angli, Zhang, Min, Powell, Joseph E., Goddard, Michael E., Wray, Naomi R., Visscher, Peter M., McRae, Allan F. and Yang, Jian (2019). Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. Science Advances, 5 (8) eaaw3538, 1-12. doi: 10.1126/sciadv.aaw3538
Li, Yizhen, Wang, Huanwei, Wang, Xiaoling, Jin, Wen, Tan, Yun, Fang, Hai, Chen, Saijuan, Chen, Zhu and Wang, Kankan (2016). Genome-wide studies identify a novel interplay between AML1 and AML1/ETO in t(8;21) acute myeloid leukemia. Blood, 127 (2), 233-242. doi: 10.1182/blood-2015-03-626671
Zhang, Hui, Mi, Jian-Qing, Fang, Hai, Wang, Zhao, Wang, Chun, Wu, Lin, Zhang, Bin, Minden, Mark, Yang, Wen-Tao, Wang, Huan-Wei, Li, Jun-Min, Xi, Xiao-Dong, Chen, Sai-Juan, Zhang, Ji, Chen, Zhu and Wang, Kan-Kan (2013). Preferential eradication of acute myelogenous leukemia stem cells by fenretinide. Proceedings of the National Academy of Sciences, 110 (14), 5606-5611. doi: 10.1073/pnas.1302352110
Thesis
Wang, Huanwei (2021). Understanding the genetic and environmental variations in human complex traits. PhD Thesis, Institute for Molecular Bioscience, The University of Queensland. doi: 10.14264/a4f8ceb