Book Chapters
Lucke, Andrew, Stirling, Charles J. M. and BÖhmer, Volker (2002). Mono- and multi-layers. Calixarenes 2001. (pp. 612-626) edited by Zouhair Asfari, Volker Böhmer, Jack Harrowfield and Jacques Vicens. Dordrecht, Netherlands : Kluwer Academic Publishers. doi: 10.1007/0-306-47522-7_33
Lucke, Andrew J. and Stirling, Charles J. M. (2000). Calixarenes in thin film supramolecular materials. Calixarenes in Action. (pp. 172-202) edited by Luigi Mandolini and Rocco Ungaro. London, United Kingdom: Imperial College Press. doi: 10.1142/9781848160354_0008
Journal Articles
Sinniah, Enakshi, Wu, Zhixuan, Shen, Sophie, Naval-Sanchez, Marina, Chen, Xiaoli, Lim, Junxian, Helfer, Abbigail, Iyer, Abishek, Tng, Jiahui, Lucke, Andrew J., Reid, Robert C., Redd, Meredith A., Nefzger, Christian M., Fairlie, David P. and Palpant, Nathan J. (2022). Temporal perturbation of histone deacetylase activity reveals a requirement for HDAC1–3 in mesendoderm cell differentiation. Cell Reports, 39 (7) 110818, 1-21. doi: 10.1016/j.celrep.2022.110818
Chua, Ming Jang, Tng, Jiahui, Hesping, Eva, Fisher, Gillian M., Goodman, Christopher D., Skinner-Adams, Tina, Do, Darren, Lucke, Andrew J., Reid, Robert C., Fairlie, David P. and Andrews, Katherine T. (2021). Histone deacetylase inhibitor AR-42 and achiral analogues kill malaria parasites in vitro and in mice. International Journal for Parasitology: Drugs and Drug Resistance, 17, 118-127. doi: 10.1016/j.ijpddr.2021.08.006
Mak, Jeffrey Y. W., Wu, Kai-Chen, Gupta, Praveer K., Barbero, Sheila, McLaughlin, Maddison G., Lucke, Andrew J., Tng, Jiahui, Lim, Junxian, Loh, Zhixuan, Sweet, Matthew J, Reid, Robert C., Liu, Ligong and Fairlie, David P. (2021). HDAC7 inhibition by phenacetyl and phenylbenzoyl hydroxamates. Journal of Medicinal Chemistry, 64 (4), 2186-2204. doi: 10.1021/acs.jmedchem.0c01967
Sheng, Yong Hua, Giri, Rabina, Davies, Julie, Schreiber, Veronika, Alabbas, Saleh, Movva, Ramya, He, Yaowu, Wu, Andy, Hooper, John, McWhinney, Brett, Oancea, Iulia, Kijanka, Gregor, Hasnain, Sumaira, Lucke, Andrew J., Fairlie, David P., McGuckin, Michael A., Florin, Timothy H. and Begun, Jakob (2021). A nucleotide analog prevents colitis associated cancer via Β-catenin independently of inflammation and autophagy. Cellular and Molecular Gastroenterology and Hepatology, 11 (1), 33-53. doi: 10.1016/j.jcmgh.2020.05.012
Tng, Jiahui, Lim, Junxian, Wu, Kai-Chen, Lucke, Andrew J., Xu, Weijun, Reid, Robert C. and Fairlie, David P. (2020). Achiral derivatives of hydroxamate AR-42 potently inhibit class I HDAC enzymes and cancer cell proliferation. Journal of Medicinal Chemistry, 63 (11) acs.jmedchem.0c00230, 5956-5971. doi: 10.1021/acs.jmedchem.0c00230
Kim, Soo-Hyun, Redvers, Richard P., Chi, Lap Hing, Ling, Xiawei, Lucke, Andrew J., Reid, Robert C., Fairlie, David P., Baptista Moreno Martin, Ana Carolina, Anderson, Robin L., Denoyer, Delphine and Pouliot, Normand (2018). Identification of brain metastasis genes and therapeutic evaluation of histone deacetylase inhibitors in a clinically relevant model of breast cancer brain metastasis. Disease Models and Mechanisms, 11 (7) Y, DMM034850. doi: 10.1242/dmm.034850
Nielsen, Daniel S., Shepherd, Nicholas E., Xu, Weijun, Lucke, Andrew J., Stoermer, Martin J. and Fairlie, David P. (2017). Orally absorbed cyclic peptides. Chemical Reviews, 117 (12), 8094-8128. doi: 10.1021/acs.chemrev.6b00838
Bagnall, Neil H., Hines, Barney M., Lucke, Andrew J., Gupta, Praveer K., Reid, Robert C., Fairlie, David P. and Kotze, Andrew C. (2017). Insecticidal activities of histone deacetylase inhibitors against a dipteran parasite of sheep, Lucilia cuprina. International Journal for Parasitology: Drugs and Drug Resistance, 7 (1), 51-60. doi: 10.1016/j.ijpddr.2017.01.001
Harjani, Jitendra R., Yap, Beow Keat, Leung, Eleanor W. W., Lucke, Andrew, Nicholson, Sandra E., Scanlon, Martin J., Chalmers, David K., Thompson, Philip E., Norton, Raymond S. and Baell, Jonathan B. (2016). Design, Synthesis, and Characterization of Cyclic Peptidomimetics of the Inducible Nitric Oxide Synthase Binding Epitope That Disrupt the Protein–Protein Interaction Involving SPRY Domain-Containing Suppressor of Cytokine Signaling Box Protein (SPSB) 2 and Inducible Nitric Oxide Synthase. Journal of Medicinal Chemistry, 59 (12), 5799-5809. doi: 10.1021/acs.jmedchem.6b00386
Nielsen, Daniel S., Lohman, Rink-Jan, Hoang, Huy Ngoc, Hill, Timothy A., Jones, Alun, Lucke, Andrew J. and Fairlie, David P. (2015). Flexibility versus rigidity for orally bioavailable cyclic hexapeptides. Chembiochem, 16 (16), 2289-2293. doi: 10.1002/cbic.201500441
Perry, Samuel R., Xu, Weijun, Wirija, Anna, Lim, Junxian, Yau, Mei-Kwan, Stoermer, Martin J., Lucke, Andrew J. and Fairlie, David P. (2015). Three homology models for PAR2 derived from different templates: Application to antagonist discovery. Journal of Chemical Information And Modeling, 55 (6), 1181-1191. doi: 10.1021/acs.jcim.5b00087
Xu, Weijun, Lucke, Andrew J. and Fairlie, David P. (2015). Comparing sixteen scoring functions for predicting biological activities of ligands for protein targets. Journal of Molecular Graphics and Modelling, 57, 76-88. doi: 10.1016/j.jmgm.2015.01.009
Nielsen, Daniel S., Hoang, Huy N., Lohman, Rink-Jan, Hill, Timothy A., Lucke, Andrew J., Craik, David J., Edmonds, David J., Griffith, David A., Rotter, Charles J., Ruggeri, Roger B., Price, David A., Liras, Spiros and Fairlie, David P. (2014). Improving on nature: making a cyclic heptapeptide orally bioavailable. Angewandte Chemie - International Edition, 53 (45), 12059-12063. doi: 10.1002/anie.201405364
Hill, Timothy A., Lohman, Rink-Jan, Hoang, Huy N., Nielsen, Daniel S., Scully, Conor C. G., Kok, W. Mei, Liu, Ligong, Lucke, Andrew J., Stoermer, Martin J., Schroeder, Christina I., Chaousis, Stephanie, Colless, Barbara, Bernhardt, Paul V., Edmonds, David J., Griffith, David A., Rotter, Charles J., Ruggeri, Roger B., Price, David A., Liras, Spiros, Craik, David J. and Fairlie, David P. (2014). Cyclic penta- and hexaleucine peptides without N-methylation are orally absorbed. ACS Medicinal Chemistry Letters, 5 (10), 1148-1151. doi: 10.1021/ml5002823
Sumanadasa, Subathdrage D. M., Goodman, Christopher D., Lucke, Andrew J., Skinner-Adams, Tina, Sahama, Ishani, Haque, Ashraful, Do, Tram Anh, McFadden, Geoffrey I., Fairlie, David P. and Andrews, Katherine T. (2012). Antimalarial activity of the anticancer histone deacetylase inhibitor SB939. Antimicrobial Agents and Chemotherapy, 56 (7), 3849-3856. doi: 10.1128/AAC.00030-12
Cantley, M. D., Fairlie, D. P., Bartold, P. M., Rainsford, K. D., Le, G. T., Lucke, A. J., Holding, C. A. and Haynes, D. R. (2011). Inhibitors of histone deacetylases in class I and class II suppress human osteoclasts in vitro. Journal of Cellular Physiology, 226 (12), 3233-3241. doi: 10.1002/jcp.22684
Cantley, M. D., Bartold, P. M., Marino, V., Fairlie, D. P., Le, G. T., Lucke, A. J. and Haynes, D. R. (2011). Histone deacetylase inhibitors and periodontal bone loss. Journal of Periodontal Research, 46 (6), 697-703. doi: 10.1111/j.1600-0765.2011.01392.x
Singh, Yogendra, Sharpe, Philip C., Hoang, Huy N., Lucke, Andrew J., McDowall, Alasdair W., Bottomley, Stephen P. and Fairlie, David P. (2011). Amyloid formation from an α-helical peptide bundle is seeded by 310-helix aggregates. Chemistry: A European Journal, 17 (1), 151-160. doi: 10.1002/chem.201002500
Gupta, Praveer K., Reid, Robert C., Liu, Ligong, Lucke, Andrew J., Broomfield, Steve A., Andrews, Melanie R., Sweet, Matthew J. and Fairlie, David P. (2010). Inhibitors selective for HDAC6 in enzymes and cells. Bioorganic & Medicinal Chemistry Letters, 20 (23), 7067-7070. doi: 10.1016/j.bmcl.2010.09.100
Wheatley, Nicole C., Andrews, Katherine T., Tran, Truc L., Lucke, Andrew J., Reid, Robert C. and Fairlie, David P. (2010). Antimalarial histone deacetylase inhibitors containing cinnamate or NSAID components. Bioorganic & Medicinal Chemistry Letters, 20 (23), 7080-7084. doi: 10.1016/j.bmcl.2010.09.096
Andrews, K. T., Tran, T. N., Lucke, A. J., Kahnberg, P., Le, G. T., Boyle, G. M., Gardiner, D. L., Skinner-Adams, T. S. and Fairlie, D. P. (2008). Potent antimalarial activity of histone deacetylase inhibitor analogues. Antimicrobial agents and chemotherapy, 52 (4), 1454-1461. doi: 10.1128/AAC.00757-07
Lucke, A., Boyle, G. M., Parsons, P. G. and Fairlie, D. (2006). New Cysteine Derivatives with Antiproliferative Activity on Melanoma Cells. Medicinal Chemistry, 2 (2), 123-132. doi: 10.2174/157340606776056124
Kahnberg, P. C., Lucke, A., Glenn, M. P., Boyle, G. M., Tyndall, J. D., Parsons, P. G. and Fairlie, D. P. (2006). Design, Synthesis, Potency and Cytoselectivity of Anticancer Agents Derived by Parallel Synthesis from alpha-Aminosuberic Acid. Journal of Medicinal Chemistry, 49 (26), 7611-7622. doi: 10.1021/jm050214x
Lucke, Andrew J. and Young, David J. (2005). Electrophilic cleavage of cyclopropylmethystannanes: An experimental comparison of σ−σ and σ−π conjugation. Journal of Organic Chemistry, 70 (9), 3579-3583. doi: 10.1021/jo047822p
Singh, Y, Stoermer, MJ, Lucke, AJ, Guthrie, T and Fairlie, DP (2005). Structural mimicry of two cytochrome b(562) interhelical loops using macrocycles constrained by oxazoles and thiazoles. Journal of The American Chemical Society, 127 (18), 6563-6572. doi: 10.1021/ja0455300
Collyer, Stuart, Davis, Frank, Lucke, Andrew, Stirling, Charles J. M. and Higson, Séamus P. J. (2004). An investigation into outer-surface biofouling and electrode passivation effects on gold electrodes modified with Calix[4]resorcinarenetetrathiol and a PEG derivative on exposure to whole human blood. Electroanalysis, 16 (4), 275-281. doi: 10.1002/elan.200402829
Collyer, Stuart D., Davis, Frank, Lucke, Andrew, Stirling, Charles J.M. and Higson, Séamus P.J. (2003). The electrochemistry of the ferri/ferrocyanide couple at a calix[4]resorcinarenetetrathiol-modified gold electrode as a study of novel electrode modifying coatings for use within electro-analytical sensors. Journal of Electroanalytical Chemistry, 549 (SUPPL.), 119-127. doi: 10.1016/S0022-0728(03)00270-5
Lucke, AJ, Tyndall, JDA, Singh, Y and Fairlie, DP (2003). Designing supramolecular structures from models of cyclic peptide scaffolds with heterocyclic constraints. Journal of Molecular Graphics & Modelling, 21 (5), 341-355. doi: 10.1016/S1093-3263(02)00181-X
Singh, Y, Stoermer, MJ, Lucke, AJ, Glenn, MP and Fairlie, DP (2002). Regioselective synthesis of antiparallel loops on a macrocyclic scaffold constrained by oxazoles and thiazoles. Organic Letters, 4 (20), 3367-3370. doi: 10.1021/ol026463m
Davis, F, Lucke, AJ, Smith, KA and Stirling, CJM (1998). Order and structure in Langmuir-Blodgett mono- and multilayers of resorcarenes. Langmuir, 14 (15), 4180-4185. doi: 10.1021/la980078h
Lucke, Andrew J. and Young, David J. (1994). The regiochemistry of cyclopropylcarbinylstannane ring fission. Tetrahedron Letters, 35 (10), 1609-1612. doi: 10.1016/s0040-4039(00)76771-2
Lucke, Andrew J and Young, David J (1991). The electrophilic cleavage of cyclopropylcarbinylstannanes. Confirmation of traylor's prediction. Tetrahedron Letters, 32 (6), 807-810. doi: 10.1016/s0040-4039(00)74893-3
Conference Papers
Plisson, Fabien , Lucke, Andrew, Nielsen, Daniel , Stoermer, Martin J. and Fairlie, David (2014). Mining physicochemical features that contribute to oral bioavailability in peptide middle space. European QSAR Symposium, St Petersburg, Russia, September 2014.
Fairlie, David P., Stoermer, Martin, Lucke, Andrew, Lohman, Rink-Jan, Liu, Ligong and Ruiz-Gomez, Gloria (2011). Towards orally bioavailable peptides and peptidomimetics. 241st National Meeting and Exposition of the American-Chemical-Society (ACS), Anaheim, CA, United States, 27-31 March 2011. Washington, DC, United States: American Chemical Society.
Andrews, Kathy T., Tran, Thanh N., Lucke, Andrew, Kahnberg, Pia, Lee, G. T., Skinner-Adams, Tina, Gardiner, Donald L. and Fairlie, David P. (2007). Plasmodium falciparum histone deacetylases: Enzymes involved in gene regulation as new antimalarial drug targets. 56th Annual Meeting of the American-Society-of-Tropical-Medicine-and-Hygiene, Philadelphia, PA United States, 04-08 November 2007. Deerfield, IL United States: American Society of Tropical Medicine and Hygiene.
Data Collection
Nielsen, Daniel S., Shepherd, Nicholas E., Xu, Weijun, Lucke, Andrew J., Stoermer, Martin J. and Fairlie, David P. (2019). Supplementary Data tables for: Orally absorbed cyclic peptides. The University of Queensland. (Dataset) doi: 10.14264/uql.2019.213