Dr Vikas Tillu
Research Officer
Institute for Molecular Bioscience
+61 7 334 62335
Journal Articles
Das Gupta, Kaustav, Shakespear, Melanie R., Curson, James E.B., Murthy, Ambika M.V., Iyer, Abishek, Hodson, Mark P., Ramnath, Divya, Tillu, Vikas A., von Pein, Jessica B., Reid, Robert C., Tunny, Kathryn, Hohenhaus, Daniel M., Moradi, Shayli Varasteh, Kelly, Gregory M., Kobayashi, Takumi, Gunter, Jennifer H., Stevenson, Alexander J., Xu, Weijun, Luo, Lin, Jones, Alun, Johnston, Wayne A., Blumenthal, Antje, Alexandrov, Kirill, Collins, Brett M., Stow, Jennifer L., Fairlie, David P. and Sweet, Matthew J. (2020). Class IIa histone deacetylases drive toll-like receptor-inducible glycolysis and macrophage inflammatory responses via pyruvate kinase M2. Cell Reports, 30 (8) 2712-2728.e8. doi:10.1016/j.celrep.2020.02.007
McMahon, Kerrie-Ann, Wu, Yeping, Gambin, Yann, Sierecki, Emma, Tillu, Vikas A., Hall, Thomas, Martel, Nick, Okano, Satomi, Moradi, Shayli Varasteh, Ruelcke, Jayde E., Ferguson, Charles, Yap, Alpha S., Alexandrov, Kirill, Hill, Michelle M. and Parton, Robert G. (2019). Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis. Nature Communications, 10 (1) 3279, doi:10.1038/s41467-019-11111-1
Chen, Kai-En, Tillu, Vikas A., Chandra, Mintu and Collins, Brett M. (2018). Molecular basis for membrane recruitment by the PX and C2 domains of Class II Phosphoinositide 3-Kinase-C2α. Structure, 26 (12) 1612-1625.e4. doi:10.1016/j.str.2018.08.010
Healy, Michael D., Hospenthal, Manuela K., Hall, Ryan J., Chandra, Mintu, Chilton, Molly, Tillu, Vikas, Chen, Kai-En, Celligoi, Dion J., McDonald, Fiona J., Cullen, Peter J., Lott, J. Shaun, Collins, Brett M. and Ghai, Rajesh (2018). Structural insights into the architecture and membrane interactions of the conserved COMMD proteins. eLife, 7e35898, doi:10.7554/elife.35898
Tillu, Vikas A, Lim, Ye-Wheen, Kovtun, Oleksiy, Mureev, Sergey, Ferguson, Charles, Bastiani, Michele, McMahon, Kerrie-Ann, Lo, Harriet P, Hall, Thomas E, Alexandrov, Kirill, Collins, Brett M and Parton, Robert G (2018). A variable undecad repeat domain in cavin1 regulates caveola formation and stability. EMBO Reports, 19 (9) e45775, doi:10.15252/embr.201845775
Parton, Robert G, Tillu, Vikas A and Collins, Brett M (2018). Caveolae. Current Biology, 28 (8) R402-R405. doi:10.1016/j.cub.2017.11.075
Tillu, Vikas A., Kovtun, Oleksiy, McMahon, Kerrie-Ann, Collins, Brett M. and Parton, Robert G. (2015). A phosphoinositide-binding cluster in cavin1 acts as a molecular sensor for cavin1 degradation. Molecular Biology of the Cell, 26 (20) 3561-3569. doi:10.1091/mbc.E15-06-0359
Kovtun, Oleksiy, Tillu, Vikas A., Ariotti, Nicholas, Parton, Robert G. and Collins, Brett M. (2015). Cavin family proteins and the assembly of caveolae. Journal of Cell Science, 128 (7) 1269-1278. doi:10.1242/jcs.167866
Kovtun, Oleksiy, Tilu, Vikas A., Jung, WooRam, Leneva, Natalya, Ariotti, Nicholas, Chaudhary, Natasha, Mandyam, Ramya A., Ferguson, Charles, Morgan, Garry P., Johnston, Wayne A., Harrop, Stephen J., Alexandrov, Kirill, Parton, Robert G. and Collins, Brett M. (2014). Structural insights into the organization of the cavin membrane coat complex. Developmental Cell, 31 (4) 405-419. doi:10.1016/j.devcel.2014.10.002
Sheokand, Navdeep, Malhotra, Himanshu, Kumar, Santosh, Tillu, Vikas A., Chauhan, Anoop S., Raje, Chaaya I. and Raje, Manoj (2014). Moonlighting cell-surface GAPDH recruits apotransferrin to effect iron egress from mammalian cells. Journal of Cell Science, 127 (19) 4279-4291. doi:10.1242/jcs.154005
Boradia, Vishant Mahendra, Malhotra, Himanshu, Thakkar, Janak Shrikant, Tillu, Vikas Ajit, Vuppala, Bhavana, Patil, Pravinkumar, Sheokand, Nadeep, Sharma, Prerna, Chauhan, Anoop Singh, Raje, Manoj and Raje, Chaaya Iyengar (2014). Mycobacterium tuberculosis acquires iron by cell-surface sequestration and internalization of human holo-transferrin. Nature Communications, 5 (4730) 4730, 1-13. doi:10.1038/ncomms5730
Sheokand, Navdeep, Kumar, Santosh, Malhotra, Himanshu, Tillu, Vikas, Raje, Chaaya Iyengar and Raje, Manoj (2013). Secreted glyceraldehye-3-phosphate dehydrogenase is a multifunctional autocrine transferrin receptor for cellular iron acquisition. BBA - General Subjects , 1830 (6) 3816-3827. doi:10.1016/j.bbagen.2013.03.019
Pande, Abhay H. and Tillu, Vikas A. (2011). Membrane lipid composition differentially modulates the function of human plasma platelet activating factor-acetylhydrolase. Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids, 1811 (1) 46-56. doi:10.1016/j.bbalip.2010.09.002
Kar, Subhabrata, Tillu, Vikas A., Meena, Shiv Charan and Pande, Abhay H. (2011). Closely related oxidized phospholipids differentially modulate the physicochemical properties of lipid particles. Chemistry and Physics of Lipids, 164 (1) 54-61. doi:10.1016/j.chemphyslip.2010.10.006
Conference Papers
Kovtun, O., Tillu, V., Jung, W., Leneva, N., Ariotti, N., Alexandrov, K., Parton, R. and Collins, B. (2014).Structural dissection of architecture of caveolar protein coat. FEBS EMBO 2014 Conference, Paris France, Aug 30-Sep 04, 2014. HOBOKEN :WILEY-BLACKWELL.
Collins, B., Kovtun, O., Tillu, V. and Parton, R. (2014).Molecular organization and membrane interactions of the cavin coat complex. FEBS EMBO 2014 Conference, Paris France, Aug 30-Sep 04, 2014. HOBOKEN :WILEY-BLACKWELL.
Sheokand, N., Malhotra, H., Tillu, V., Kumar, S. and Raje, M. (2012).Cell surface GAPDH recruits Apo Tf to facilitate iron export in iron overloaded cells.. AMER SOC CELL BIOLOGY.
Thesis
Tillu, Vikas Ajit (2016). Structural and functional characterisation of the cavin membrane coat complex. PhD Thesis, Institute for Molecular Bioscience, The University of Queensland. doi:10.14264/uql.2016.815