Dr Zyta M Ziora
Senior Research Officer
Institute for Molecular Bioscience
+61 7 334 62202
Researcher biography
Dr Zyta Ziora received PhD (Wroclaw University of Science & Technology, Poland) in chemistry and has wide range of experience in development of antimalarial therapeutics (the University of Montpellier, France), antibacterial agents, enzyme inhibitors and drug candidates against Alzheimer disease (Kyoto Pharmaceutical University, Japan). Her research time is currently dedicated mainly to projects devoted to the modification of existing antibiotics, and complexing them with additional antimicrobial agents, like metal ions, to produce more potent alternatives and by this to overcome the drug resistance of superbugs. She is also working on alternative to antibiotics nature-derived compounds with antimicrobial and anticancer potency, such poliphenolic derivatives to control tyrosinase function.
Book Chapters
Jain, Marut, Noor, Aisha, Sahoo, Abhisek, Pant, Kamal K., Ziora, Zyta M. and Blaskovich, Mark A. T. (2024). Biodegradation of petrochemical refinery wastewater. Biodegradation of toxic and hazardous chemicals. (pp. 1-13) edited by Kashyap K. Dubey, Kamal K. Pant, Ashok Pandey and Maria Ángeles Sanromán. Boca Raton, FL, United States: CRC Press. doi: 10.1201/9781003391487-1
Hansford, Karl A., Ziora, Zyta M., Cooper, Matthew A. and Blaskovich, Mark A. T. (2020). Solid-phase synthesis of octapeptin lipopeptides. Peptide synthesis: methods and protocols. (pp. 199-213) edited by Waleed M. Hussein, Mariusz Skwarczynski and Istvan Toth. New York, NY United States: Humana Press. doi: 10.1007/978-1-0716-0227-0_13
Hamada, Yoshio and Ziora, Zyta M. (2020). Peptidomimetic synthesis: drug discovery for Alzheimer's disease. Peptide synthesis: methods and protocols. (pp. 215-223) edited by Waleed M. Hussein, Mariusz Skwarczynski and Istvan Toth. New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-0227-0_14
Mital, Mariusz, Sęk, Jakub P. and Ziora, Zyta M. (2020). Metal-peptide complexes to study neurodegenerative diseases. Peptide synthesis: methods and protocols. (pp. 323-336) edited by Waleed M. Hussein, Mariusz Skwarczynski and Istvan Toth. New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-0227-0_22
Ziora, Zyta, Skwarczynski, Mariusz and Kiso, Yoshiaki (2011). Medicinal chemistry of a-hydroxy-b-amino acids. Amino Acids, Peptides and Proteins in Organic Chemistry: Volume 4 - Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis. (pp. 189-234) edited by Andrew B. Hughes. Weinheim, Germany: Wiley-VCH. doi: 10.1002/9783527631827.ch6
Journal Articles
Bojarska, Joanna, Breza, Martin, Borowiecki, Pawel, Madura, Izabela D., Kaczmarek, Krzysztof, Ziora, Zyta M. and Wolf, Wojciech M. (2024). An experimental and computational investigation of the cyclopentene-containing peptide-derived compounds: focus on pseudo-cyclic motifs via intramolecular interactions. Royal Society Open Science, 11 (10) ARTN 40962. doi: 10.1098/rsos.240962
Yuan, Ye, Li, Muzi, Apostolopoulos, Vasso, Matsoukas, John, Wolf, Wojciech M., Blaskovich, Mark A.T., Bojarska, Joanna and Ziora, Zyta M. (2024). Tetrazoles: A multi-potent motif in drug design. European Journal of Medicinal Chemistry, 279 116870, 116870. doi: 10.1016/j.ejmech.2024.116870
Li, Hongze, Yang, Zhihe, Khan, Sadaf Aiman, Walsh, Laurence J., Seneviratne, Chaminda Jayampath and Ziora, Zyta M. (2024). Characteristics of metallic nanoparticles (especially silver nanoparticles) as anti-biofilm agents. Antibiotics, 13 (9) 819. doi: 10.3390/antibiotics13090819
Noor, Aisha, Moyle, Peter M., Malik, Anushree, Ziora, Zyta M and Pant, K.K. (2024). Transformative upcycling of fruit-vegetable waste for nutraceutical and pharmaceutical breakthroughs and circular economy evolution. Process Safety and Environmental Protection, 187, 1022-1036. doi: 10.1016/j.psep.2024.05.002
Jain, Marut, Sahoo, Abhisek, Mishra, Deepti, Aiman Khan, Sadaf, Kishore Pant, Kamal, Ziora, Zyta M. and Blaskovich, Mark A.T. (2024). Modelling and statistical interpretation of phenol adsorption behaviour of 3-Dimensional hybrid aerogel of waste-derived carbon nanotubes and graphene oxide. Chemical Engineering Journal, 490 151351, 1-17. doi: 10.1016/j.cej.2024.151351
Khan, Sadaf Aiman, Zeng, Junya, Jain, Marut, Pant, Kamal Kishore, Ziora, Zyta Maria, Blaskovich, Mark A.T. and Seneviratne, Chaminda Jayampath (2024). Facile one-pot fabrication of multifunctional silver nanoparticles utilizing biowaste for efficient pollutant degradation, heavy metal sensing, and bactericidal activity. Materials Chemistry and Physics, 322 129606, 129606. doi: 10.1016/j.matchemphys.2024.129606
El-Meligy, Mahmoud A., Abd El-Monaem, Eman M., Eltaweil, Abdelazeem S., Mohy-Eldin, Mohamed S., Ziora, Zyta M., Heydari, Abolfazl and Omer, Ahmed M. (2024). Recent advancements in metallic Au- and Ag-based chitosan nanocomposite derivatives for enhanced anticancer drug delivery. Molecules, 29 (10) 2393. doi: 10.3390/molecules29102393
Zhao, Ziyao, Bashiri, Sahra, Ziora, Zyta M., Toth, Istvan and Skwarczynski, Mariusz (2024). COVID-19 variants and vaccine development. Viruses, 16 (5) 757, 757. doi: 10.3390/v16050757
Khan, Sadaf Aiman, Jain, Marut, Pant, Kamal Kishore, Ziora, Zyta Maria and Blaskovich, Mark A.T. (2024). Photocatalytic degradation of parabens: A comprehensive meta-analysis investigating the environmental remediation potential of emerging pollutant. Science of The Total Environment, 920 171020, 171020. doi: 10.1016/j.scitotenv.2024.171020
Yusufoğlu, Büşra, Kezer, Gizem, Wang, Yifan, Ziora, Zyta M and Esatbeyoglu, Tuba (2024). Bio-recycling of spent coffee grounds: Recent advances and potential applications. Current Opinion in Food Science, 55 101111, 101111. doi: 10.1016/j.cofs.2023.101111
Jin, Wanli, Stehbens, Samantha J., Barnard, Ross T., Blaskovich, Mark A. T. and Ziora, Zyta M. (2024). Dysregulation of tyrosinase activity: a potential link between skin disorders and neurodegeneration. Journal of Pharmacy and Pharmacology, 76 (1), 13-22. doi: 10.1093/jpp/rgad107
Ali, Ali M., Hamed, Abdelrahman M., Taher, Mahmoud A., Abdallah, Mohamed H., Abdel-Motaleb, Mohamed, Ziora, Zyta M. and Omer, Ahmed M. (2023). Fabrication of antibacterial and antioxidant ZnO-impregnated amine-functionalized chitosan bio-nanocomposite membrane for advanced biomedical applications. Molecules, 28 (20) 7034, 1-18. doi: 10.3390/molecules28207034
Bojarska, Joanna, Breza, Martin, Remko, Milan, Yuan, Ye, Ziora, Zyta M., Chai, Tsun-Thai, Madura, Izabela D., Kaczmarek, Krzysztof, Blaskovich, Mark A.T. and Wolf, Wojciech M. (2023). A supramolecular self-assembly of peptide-derived compounds via 1,5-disubstituted tetrazole-based supramolecular synthons: An experimental and computational study. Journal of Molecular Structure, 1288 135732, 135732. doi: 10.1016/j.molstruc.2023.135732
Alharthi, Sitah, Ziora, Zyta Maria, Mustafa, Gulam, Chaubey, Pramila, El Kirdasy, Ahmed Farag and Alotaibi, Ghallab (2023). β-caryophyllene-loaded microemulsion-based topical hydrogel: a promising carrier to enhance the analgesic and anti-inflammatory outcomes. Gels, 9 (8) 634, 1-16. doi: 10.3390/gels9080634
Khan, Sadaf Aiman, Jain, Marut, Pant, Kamal Kishore, Ziora, Zyta Maria and Blaskovich, Mark A. T. (2023). Photocatalytic degradation of methylparaben using green nanosilver supported on reduced graphene oxide. Industrial and Engineering Chemistry Research, 62 (17), 6646-6659. doi: 10.1021/acs.iecr.3c00146
Alharthi, Sitah, Popat, Amirali, Ziora, Zyta Maria and Moyle, Peter Michael (2023). Sortase A Inhibitor Protein Nanoparticle Formulations Demonstrate Antibacterial Synergy When Combined with Antimicrobial Peptides. Molecules, 28 (5) 2114, 1-17. doi: 10.3390/molecules28052114
Quah, Yixian, Tong, Shi-Ruo, Bojarska, Joanna, Giller, Katrin, Tan, Sheri-Ann, Ziora, Zyta Maria, Esatbeyoglu, Tuba and Chai, Tsun-Thai (2023). Bioactive peptide discovery from edible insects for potential applications in human health and agriculture. Molecules, 28 (3) 1233, 1-23. doi: 10.3390/molecules28031233
Nguyen, Chau Ngoc Minh, Nirmal, Nilesh Prakash, Sultanbawa, Yasmina and Ziora, Zyta M. (2023). Antioxidant and antibacterial activity of four tannins isolated from different sources and their effect on the shelf-life extension of vacuum-packed minced meat. Foods, 12 (2) 354, 1-16. doi: 10.3390/foods12020354
Khan, Sadaf Aiman, Jain, Marut, Pandey, Ashish, Pant, Kamal Kishore, Ziora, Zyta Maria, Blaskovich, Mark A. T., Shetti, Nagaraj P. and Aminabhavi, Tejraj M. (2022). Leveraging the potential of silver nanoparticles-based materials towards sustainable water treatment. Journal of Environmental Management, 319 115675, 115675. doi: 10.1016/j.jenvman.2022.115675
Wahid, Muqeet, Saqib, Fatima, Qamar, Muhammad and Ziora, Zyta M. (2022). Antispasmodic activity of the ethanol extract of Citrullus lanatus seeds: justifying ethnomedicinal use in Pakistan to treat asthma and diarrhea. Journal of Ethnopharmacology, 295 115314, 115314. doi: 10.1016/j.jep.2022.115314
Blaskovich, Mark A.T., Hansford, Karl A., Butler, Mark S., Ramu, Soumya, Kavanagh, Angela M., Jarrad, Angie M., Prasetyoputri, Anggia, Pitt, Miranda E., Huang, Johnny X., Lindahl, Fredrik, Ziora, Zyta M., Bradford, Tanya, Muldoon, Craig, Rajaratnam, Premraj, Pelingon, Ruby, Edwards, David J., Zhang, Bing, Amado, Maite, Elliott, Alysha G., Zuegg, Johannes, Coin, Lachlan, Woischnig, Anne-Kathrin, Khanna, Nina, Breidenstein, Elena, Stincone, Anna, Mason, Clive, Khan, Nawaz, Cho, Hye-Kyung, Karau, Melissa J. ... Cooper, Matthew A. (2022). A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections. Science Translational Medicine, 14 (662) abj2381. doi: 10.1126/scitranslmed.abj238
Blaskovich, Mark A.T., Hansford, Karl A., Butler, Mark S., Ramu, Soumya, Kavanagh, Angela M., Jarrad, Angie M., Prasetyoputri, Anggia, Pitt, Miranda E., Huang, Johnny X., Lindahl, Fredrik, Ziora, Zyta M., Bradford, Tanya, Muldoon, Craig, Rajaratnam, Premraj, Pelingon, Ruby, Edwards, David J., Zhang, Bing, Amado, Maite, Elliott, Alysha G., Zuegg, Johannes, Coin, Lachlan, Woischnig, Anne-Kathrin, Khanna, Nina, Breidenstein, Elena, Stincone, Anna, Mason, Clive, Khan, Nawaz, Cho, Hye-Kyung, Karau, Melissa J. ... Cooper, Matthew A. (2022). A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections. Science Translational Medicine, 14 (662) abj2381, 1-16. doi: 10.1126/scitranslmed.abj2381
Apostolopoulos, Vasso, Bojarska, Joanna, Chai, Tsun-Thai, Feehan, Jack, Kaczmarek, Krzysztof, Matsoukas, John M., Paredes Lopez, Octavio, Saviano, Michele, Skwarczynski, Mariusz, Smith-Carpenter, Jillian, Venanzi, Mariano, Wolf, Wojciech M., Zielenkiewicz, Piotr and Ziora, Zyta M. (2022). New Advances in Short Peptides: Looking Forward. Molecules, 27 (11) 3635, 3635. doi: 10.3390/molecules27113635
Somashekar, M. N., Chetana, P. R., Chethan, B. S., Rajegowda, H. R., Cooper, M. A., Ziora, Z. M., Lokanath, N. K., Ganapathy, P.S. Sujan and Srinatha, B. S. (2022). Synthesis and characterization of Zinc(II) complex with ONO donor type new phenylpropanehydrazide based ligand: crystal structure, Hirshfeld surface analysis, DFT, energy frameworks and molecular docking. Journal of Molecular Structure, 1255 132429, 132429. doi: 10.1016/j.molstruc.2022.132429
Alharthi, Sitah, Ziora, Zyta M., Janjua, Taskeen, Popat, Amirali and Moyle, Peter M. (2022). Formulation and biological evaluation of mesoporous silica nanoparticles loaded with combinations of sortase A inhibitors and antimicrobial peptides. Pharmaceutics, 14 (5) 986, 986. doi: 10.3390/pharmaceutics14050986
Jain, Marut, Khan, Sadaf Aiman, Sahoo, Abhisek, Dubey, Prashant, Pant, Kamal Kishore, Ziora, Zyta Maria and Blaskovich, Mark A.T. (2022). Statistical evaluation of cow-dung derived activated biochar for phenol adsorption: adsorption isotherms, kinetics, and thermodynamic studies. Bioresource Technology, 352 127030, 127030. doi: 10.1016/j.biortech.2022.127030
Qamar, Muhammad, Akhtar, Saeed, Ismail, Tariq, Wahid, Muqeet, Ali, Sajed, Nazir, Yasir, Murtaza, Shahid, Abbas, Malik Waseem and Ziora, Zyta M. (2022). Syzygium cumini (L.) Skeels extracts; in vivo anti-nociceptive, anti-inflammatory, acute and subacute toxicity assessment. Journal of Ethnopharmacology, 287 114919, 114919. doi: 10.1016/j.jep.2021.114919
Qamar, Muhammad, Akhtar, Saeed, Barnard, Ross T., Sestili, Piero, Ziora, Zyta M., Lazarte, Claudia E. and Ismail, Tariq (2022). Antiinflammatory and anticancer properties of Grewia asiatica crude extracts and fractions: a bioassay-guided approach. BioMed Research International, 2022 2277417, 1-14. doi: 10.1155/2022/2277417
Skwarczynski, Mariusz, Bashiri, Sahra, Yuan, Ye, Ziora, Zyta M., Nabil, Osama, Masuda, Keita, Khongkow, Mattaka, Rimsueb, Natchanon, Cabral, Horacio, Ruktanonchai, Uracha, Blaskovich, Mark A. T. and Toth, Istvan (2022). Antimicrobial activity enhancers: towards smart delivery of antimicrobial agents. Antibiotics, 11 (3) 412, 412. doi: 10.3390/antibiotics11030412
Omer, Ahmed M., Dey, Rana, Eltaweil, Abdelazeem S., Abd El-Monaem, Eman M. and Ziora, Zyta M. (2022). Insights into recent advances of chitosan-based adsorbents for sustainable removal of heavy metals and anions. Arabian Journal of Chemistry, 15 (2) 103543, 103543. doi: 10.1016/j.arabjc.2021.103543
Qamar, Muhammad, Akhtar, Saeed, Ismail, Tariq, Wahid, Muqeet, Abbas, Malik Waseem, Mubarak, Mohammad S., Yuan, Ye, Barnard, Ross T., Ziora, Zyta M. and Esatbeyoglu, Tuba (2022). Phytochemical profile, biological properties, and food applications of the medicinal plant Syzygium cumini. Foods, 11 (3) 378, 378. doi: 10.3390/foods11030378
Qamar, Muhammad, Akhtar, Saeed, Ismail, Tariq, Wahid, Muqeet, Barnard, Ross T., Esatbeyoglu, Tuba and Ziora, Zyta M. (2021). The chemical composition and health-promoting effects of the Grewia species—a systematic review and meta-analysis. Nutrients, 13 (12) 4565, 4565. doi: 10.3390/nu13124565
Alharthi, Sitah, Ziora, Zyta Maria and Moyle, Peter Michael (2021). Optimized protocols for assessing libraries of poorly soluble sortase A inhibitors for antibacterial activity against medically-relevant bacteria, toxicity and enzyme inhibition. Bioorganic and Medicinal Chemistry, 52 116527, 116527. doi: 10.1016/j.bmc.2021.116527
Jain, Marut, Khan, Sadaf Aiman, Pandey, Ashish, Pant, Kamal Kishore, Ziora, Zyta Maria and Blaskovich, Mark A.T. (2021). Instructive analysis of engineered carbon materials for potential application in water and wastewater treatment. Science of The Total Environment, 793 148583, 1-19. doi: 10.1016/j.scitotenv.2021.148583
Bojarska, Joanna, Mieczkowski, Adam, Ziora, Zyta, Skwarczynski, Mariusz, Toth, Istvan, Shalash, Ahmed O., Parang, Keykavous, El-Mowafi, Shaima A., Mohammed, Eman H. M., Elnagdy, Sherif, AlKhazindar, Maha and Wolf, Wojciech M. (2021). Cyclic dipeptides: the biological and structural landscape with special focus on the anti-cancer proline-based scaffold. Biomolecules, 11 (10) 1515, 1515. doi: 10.3390/biom11101515
Alharthi, Sitah, Ebrahim Alavi, Seyed, Michael Moyle, Peter and Maria Ziora, Zyta (2021). Sortase A (SrtA) inhibitors as an alternative treatment for superbug infections. Drug Discovery Today, 26 (9), 2164-2172. doi: 10.1016/j.drudis.2021.03.019
Omer, Ahmed M., Tamer, Tamer M., Khalifa, Randa E., Eltaweil, Abdelazeem S., Agwa, Mona M., Sabra, Sally, Abd-Elmonem, Mahmoud S., Mohy-Eldin, Mohamed S. and Ziora, Zyta M. (2021). Formulation and antibacterial activity evaluation of quaternized aminochitosan membrane for wound dressing applications. Polymers, 13 (15) 2428, 1-20. doi: 10.3390/polym13152428
Naseri, Mahdi, Ziora, Zyta M., Simon, George P. and Batchelor, Warren (2021). ASSURED‐compliant point‐of‐care diagnostics for the detection of human viral infections. Reviews in Medical Virology, 32 (2) e2263, 1-17. doi: 10.1002/rmv.2263
Ul Bari, Wasim, Ur Rehman, Najeeb, Khan, Ajmal, Ahsan Halim, Sobia, Yuan, Ye, Blaskovich, Mark A.T., Ziora, Zyta M., Zahoor, Muhammad, Naz, Sumaira, Ullah, Riaz, Alotaibi, Amal and Al-Harrasi, Ahmed (2021). Bio-potency and molecular docking studies of isolated compounds from Grewia optiva J.R. Drumm. ex Burret. Molecules, 26 (7) 2019, 2019. doi: 10.3390/molecules26072019
Omer, Ahmed M., Ziora, Zyta M., Tamer, Tamer M., Khalifa, Randa E., Hassan, Mohamed A., Mohy-Eldin, Mohamed S. and Blaskovich, Mark A. T. (2021). Formulation of quaternized aminated chitosan nanoparticles for efficient encapsulation and slow eelease of curcumin. Molecules, 26 (2) 449, 1-14. doi: 10.3390/molecules26020449
Jain, Marut, Khan, Sadaf Aiman, Sharma, Komal, Jadhao, Prashant Ram, Pant, Kamal Kishore, Ziora, Zyta Maria and Blaskovich, Mark A.T. (2021). Current perspective of innovative strategies for bioremediation of organic pollutants from wastewater. Bioresource Technology, 344 (Pt B) 126305, 126305. doi: 10.1016/j.biortech.2021.126305
Qamar, Muhammad, Akhtar, Saeed, Ismail, Tariq, Yuan, Ye, Ahmad, Naveed, Tawab, Abdul, Ismail, Amir, Barnard, Ross T., Cooper, Matthew A., Blaskovich, Mark.A.T. and Ziora, Zyta M. (2021). Syzygium cumini(L.),Skeels fruit extracts: in vitro and in vivo anti-inflammatory properties. Journal of Ethnopharmacology, 271 113805, 1-12. doi: 10.1016/j.jep.2021.113805
Nazir, Yasir, Saeed, Aamer, Rafiq, Muhammad, Afzal, Samina, Ali, Anser, Latif, Muhammad, Zuegg, Johannes, Hussein, Waleed M., Fercher, Christian, Barnard, Ross T., Cooper, Matthew A., Blaskovich, Mark A.T., Ashraf, Zaman and Ziora, Zyta M. (2020). Hydroxyl substituted benzoic acid/cinnamic acid derivatives: tyrosinase inhibitory kinetics, anti-melanogenic activity and molecular docking studies. Bioorganic and Medicinal Chemistry Letters, 30 (1) 126722, 1-5. doi: 10.1016/j.bmcl.2019.126722
Cao, Yuxue, Naseri, Mahdi, He, Yan, Xu, Chun, Walsh, Laurence J. and Ziora, Zyta M. (2019). Non-antibiotic antimicrobial agents to combat biofilm-forming bacteria. Journal of Global Antimicrobial Resistance, 21, 445-451. doi: 10.1016/j.jgar.2019.11.012
Yuan, Ye, Jin, Wanli, Nazir, Yasir, Fercher, Christian, Thomas Blaskovich, Mark A., Cooper, Matthew A., Barnard, Ross T. and Ziora, Zyta M. (2019). Tyrosinase inhibitors as potential antibacterial agents. European Journal of Medicinal Chemistry, 187 111892, 111892. doi: 10.1016/j.ejmech.2019.111892
Pham, Thu D. M., Ziora, Zyta M. and Blaskovich, Mark A. T. (2019). Quinolone antibiotics. MedChemComm, 10 (10), 1719-1739. doi: 10.1039/c9md00120d
Sim, Wilson, Barnard, Ross, Blaskovich, M.A.T. and Ziora, Zyta (2018). Antimicrobial silver in medicinal and consumer applications: a patent review of the past decade (2007–2017). Antibiotics, 7 (4) 93, 93. doi: 10.3390/antibiotics7040093
Möhler, Jasper S., Sim, Wilson, Blaskovich, Mark A. T., Cooper, Matthew A. and Ziora, Zyta M. (2018). Silver bullets: a new lustre on an old antimicrobial agent. Biotechnology Advances, 36 (5), 1391-1411. doi: 10.1016/j.biotechadv.2018.05.004
Naseri-Nosar, Mahdi and Ziora, Zyta Maria (2018). Wound dressings from naturally-occurring polymers: A review on homopolysaccharide-based composites. Carbohydrate Polymers, 189, 379-398. doi: 10.1016/j.carbpol.2018.02.003
Mital, Mariusz and Ziora, Zyta (2018). Biological applications of Ru(II) polypyridyl complexes. Coordination Chemistry Reviews, 375, 434-458. doi: 10.1016/j.ccr.2018.02.013
Blaskovich, Mark A T, Hansford, Karl A., Gong, Yujing, Butler, Mark S., Muldoon, Craig, Huang, Johnny X., Ramu, Soumya, Silva, Alberto B., Cheng, Mu, Kavanagh, Angela M., Ziora, Zyta, Premraj, Rajaratnam, Lindahl, Fredrik, Bradford, Tanya A., Lee, June C., Karoli, Tomislav, Pelingon, Ruby, Edwards, David J., Amado, Maite, Elliott, Alysha G, Phetsang, Wanida, Daud, Noor Huda, Deecke, Johan E, Sidjabat, Hanna E, Ramaologa, Sefetogi, Zuegg, Johannes, Betley, Jason R, Beevers, Andrew P G, Smith, Richard A G ... Cooper, Matthew A. (2018). Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria. Nature Communications, 9 (1) 02123, 22. doi: 10.1038/s41467-017-02123-w
Möhler, Jasper S., Kolmar, Theresa, Synnatschke, Kevin, Hergert, Marcel, Wilson, Liam A., Ramu, Soumya, Elliott, Alysha G., Blaskovich, Mark A.T., Sidjabat, Hanna E., Paterson, David L., Schenk, Gerhard, Cooper, Matthew A. and Ziora, Zyta M. (2017). Enhancement of antibiotic-activity through complexation with metal ions - Combined ITC, NMR, enzymatic and biological studies. Journal of Inorganic Biochemistry, 167, 134-141. doi: 10.1016/j.jinorgbio.2016.11.028
Azmi, Fazren, Elliott, Alysha G., Marasini, Nirmal, Ramu, Soumya, Ziora, Zyta, Kavanagh, Angela M., Blaskovich, Mark A. T., Cooper, Matthew A., Skwarczynski, Mariusz and Toth, Istvan (2016). Short cationic lipopeptides as effective antibacterial agents: design, physicochemical properties and biological evaluation. Bioorganic and Medicinal Chemistry, 24 (10), 2235-2241. doi: 10.1016/j.bmc.2016.03.053
Hang, Zhou, Cooper, Matthew A. and Ziora, Zyta M. (2016). Platinum-based anticancer drugs encapsulated liposome and polymeric micelle formulation in clinical trials. Biochemical Compounds, 4. doi: 10.7243/2052-9341-4-2
McRae, Jacqui M., Ziora, Zyta M., Kassara, Stella, Cooper, Matthew A. and Smith, Paul A. (2015). Ethanol concentration influences the mechanisms of wine tannin interactions with poly(l -proline) in model wine. Journal of Agricultural and Food Chemistry, 63 (17), 4345-4352. doi: 10.1021/acs.jafc.5b00758
Cheng, Mu, Ziora, Zyta M., Hansford, Karl A., Blaskovich, Mark A., Butler, Mark S. and Cooper, Matthew A. (2014). Anti-cooperative ligand binding and dimerisation in the glycopeptide antibiotic dalbavancin. Organic and Biomolecular Chemistry, 12 (16), 2568-2575. doi: 10.1039/c3ob42428f
Simerska, Pavla, Suksamran, Tittaya, Ziora, Zyta Maria, Rivera, Fabian de Labastida, Engwerda, Christian and Toth, Istvan (2014). Ovalbumin lipid core peptide vaccines and their CD4+ and CD8+ T cell responses. Vaccine, 32 (37), 4743-4750. doi: 10.1016/j.vaccine.2014.06.049
Ahmad Fuaad, Abdullah A. H., Jia, Zhongfan, Hartas, Jon, Ziora, Zyta M., Lin, I-Chun, Moyle, Peter M., Batzloff, Michael R., Good, Michael F., Monteiro, Michael J., Skwarczynski, Mariusz and Toth, Istvan (2014). Polymer–peptide hybrids as a highly immunogenic single-dose nanovaccine. Nanomedicine, 9 (1), 35-43. doi: 10.2217/NNM.13.7
Ziora, Zyta M., Blaskovich, Mark A., Toth, Istvan and Cooper, Matthew A. (2013). ChemInform abstract: lipoamino acids as major components of absorption promoters in drug delivery. ChemInform, 44 (43), no-no. doi: 10.1002/chin.201343267
Simerska, Pavla, Ziora, Zyta Maria, Fagan, Vincent, Goodwin, Daryn, Edrous, Farrah and Toth, Istvan (2013). Design, synthesis and characterisation of mannosylated ovalbumin lipid core peptide self-adjuvanting vaccine delivery system. Drug Delivery and Translational Research, Online First (3), 1-10. doi: 10.1007/s13346-013-0173-8
Liu, Tzu-Yu, Hussein, Waleed M., Jia, Zhongfan, Ziora, Zyta M., McMillan, Nigel A. J., Monteiro, Michael J., Toth, Istvan and Skwarczynski, Mariusz (2013). Self-adjuvanting polymer-peptide conjugates as therapeutic vaccine candidates against cervical cancer. Biomacromolecules, 14 (8), 2798-2806. doi: 10.1021/bm400626w
Skwarczynski, Mariusz, Kowapradit, Jariya, Ziora, Zyta Maria and Toth, Istvan (2013). pH-Triggered peptide self-assembly into fibrils: a potential peptide-based subunit vaccine delivery platform. Biochemical Compounds, 1. doi: 10.7243/2052-9341-1-2
Zaman, Mehfuz, Abdel-Aal, Abu-Baker M., Fujita, Yoshio, Ziora, Zyta M., Batzloff, Michael R., Good, Michael F. and Toth, Istvan (2012). Structure-activity relationship for the development of a self-adjuvanting mucosally active lipopeptide vaccine against Streptococcus pyogenes. Journal of Medicinal Chemistry, 55 (19), 8515-8523. doi: 10.1021/jm301074n
Ziora, Zyta M., Blaskovich, Mark A., Toth, Istvan and Cooper, Matthew A. (2012). Lipoamino acids as major components of absorption promoters in drug delivery. Current Topics in Medicinal Chemistry, 12 (14), 1562-1580. doi: 10.2174/156802612802652448
Ziora, Zyta, Skwarczynski, Mariusz and Kiso, Yoshiaki (2012). ChemInform Abstract: Medicinal Chemistry of α-Hydroxy-β-amino Acids. ChemInform, 43 (25), no-no. doi: 10.1002/chin.201225259
Ziora, Zyta M., Wimmer, Norbert, New, Roger, Skwarczynski, Mariusz and Toth, Istvan (2012). Lipopeptides for the fragment-based pharmaceutics design. International Journal of Organic Chemistry, 2 (01), 75-81. doi: 10.4236/ijoc.2012.21013
Ziora, Zyta M., Wimmer, Norbert, New, Roger, Skwarczynski, Mariusz and Toth, Istvan (2011). Synthesis of glycolipopeptidic building blocks for carbohydrate receptor discovery. Carbohydrate Research, 346 (12), 1439-1444. doi: 10.1016/j.carres.2011.03.019
Lin, I-Chun, Liang, Mingtao, Liu, Tzu-Yu, Ziora, Zyta M., Monteiro, Michael J. and Toth, Istvan (2011). Interaction of densely polymer-coated gold nanoparticles with epithelial Caco-2 monolayers. Biomacromolecules, 12 (4), 1339-1348. doi: 10.1021/bm200116z
Skwarczynski, Mariusz, Ahmad Fuaad, Abdullah A. H., Rustanti, Lina, Ziora, Zyta M., Aqil, Mohammed, Batzloff, Michael R., Good, Michael F. and Toth, Istvan (2011). Group A streptococcal vaccine candidates based on the conserved conformational epitope from M protein. Drug Delivery Letters, 1 (1), 2-8. doi: 10.2174/2210304X11101010002
Ziora, Zyta, Maly, Alina, Lejczak, Barbara, Kafarski, Pawel, Holband, Jolanta and Wojcik, Grazyna (2010). ChemInform Abstract: Reactions of N-Phthalylamino Acid Chlorides with Trialkyl Phosphites. ChemInform, 31 (28), 1-1. doi: 10.1002/chin.200028203
Kakizawa, Taeko, Hidaka, Koushi, Hamada, Daisuke, Yamaguchi, Ryoji, Uemura, Tsuyoshi, Kitamura, Hitomi, Tagad, Harichandra D., Hamada, Takashi, Ziora, Zyta, Hamada, Yoshio, Kimura, Tooru and Kiso, Yoshiaki (2010). Tetrapeptides, as small-sized peptidic inhibitors; Synthesis and their inhibitory activity against BACE1. Journal of Peptide Science, 16 (6), 257-262. doi: 10.1002/psc.1238
Bergeon, Julie A., Ziora, Zyta M., Abdelrahim, Adel S., Pernevi, Niklas, Moss, Anne R. and Toth, Istvan (2010). In vitro and in vivo evaluation of positively charged liposaccharide derivatives as oral absorption enhancers for the delivery of anionic drugs. Journal of Pharmaceutical Sciences, 99 (5), 2333-2342. doi: 10.1002/jps.21999
Skwarczynski, Mariusz, Ziora, Zyta M., Coles, Daniel J., Lin, I-Chun and Toth, Istvan (2010). Thymine, adenine and lipoamino acid based gene delivery systems. Chemical Communications, 46 (18), 3140-3142. doi: 10.1039/b924371b
Abdelrahim, Adel. S., Ziora, Zyta M., Bergeon, Julie A., Moss, Anne R. and Toth, Istvan (2009). Design and synthesis of a series of novel, cationic liposaccharide derivatives as potential penetration enhancers for oral drug delivery. Tetrahedron, 65 (45), 9436-9442. doi: 10.1016/j.tet.2009.08.072
Ziora, Zyta and Kafarski, Pawel (2009). Amidoalkylation of Phosphorus Trichloride with Acetamide and Alkyl Oxocycloalkanecarboxylates. Phosphorus, Sulfur, and Silicon and the Related Elements, 184 (4), 1047-1053. doi: 10.1080/10426500902737356
Calas, Michele, Outtara, Mahama, Piquet, Giles, Ziora, Zyta, Bordat, Y., Ancelin, Marie L., Escale, Roger and Vial, Henri (2007). Potent antimalarial activity of 2-aminopyridinium salts, amidines, and guanidines. Journal of Medicinal Chemistry, 50 (25), 6307-6315. doi: 10.1021/jm0704752
Nagahama, Masahiro, Otsuka, Akiko, Oda, Masataka, Singh, Rajesh K., Ziora, Zyta M., Imagawa, Hiroshi, Nishizawa, Mugio and Sakurai, Jun (2007). Effect of unsaturated bonds in the sn-2 acyl chain of phosphatidylcholine on the membrane-damaging action of Clostridium perfringens alpha-toxin toward liposomes. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1768 (11), 2940-2945. doi: 10.1016/j.bbamem.2007.08.016
Ziora, Zyta, Kasai, Soko, Hidaka, Koushi, Nagamine, Ayaka, Kimura, Tooru, Hayashi, Yoshio and Kiso, Yoshiaki (2007). Design and synthesis of BACE1 inhibitors containing a novel norstatine derivative (2R,3R)-3-amino-2-hydroxy-4(phenylthio)butyric acid. Bioorganic and Medicinal Chemistry Letters, 17 (6), 1629-1633. doi: 10.1016/j.bmcl.2006.12.097
Hamada, Yoshio, Igawa, Naoto, Ikari, Hayato, Ziora, Zyta, Nguyen, Jeffrey-Tri, Yamani, Abdellah, Hidaka, Koushi, Kimura, Tooru, Saito, Kazuki, Hayashi, Yoshio, Ebina, Maiko, Ishiura, Shoichi and Kiso, Yoshiaki (2006). beta-Secretase inhibitors: Modification at the P-4 position and improvement of inhibitory activity in cultured cells. Bioorganic and Medicinal Chemistry Letters, 16 (16), 4354-4359. doi: 10.1016/j.bmcl.2006.05.046
Ziora Zyta, Kasai Soko, Hidaka Koushi, Nagamine Ayaka, Kimura Tooru, Saito K., Hayashi Yoshio and Kiso Yoshiaki (2006). Phenylthionorstatine as a transition-state mimic in BACE1 inhibitors. Peptide Science, 2006, 237-238.
Zyta, Ziora, Tooru, KImura and Yoshiaki, Kiso (2006). Small-sized BACE1 inhibitors. Drugs of the Future, 31 (1), 53-63. doi: 10.1358/dof.2006.031.01.957326
Ziora, Zyta, Kafarski, Pawel, Holband, Jolanta and Wojcik, Grazyna (2001). Synthesis and spectroscopic characterization of protected N-phosphonomethylglycine dipeptides. Journal of Peptide Science, 7 (9), 466-473. doi: 10.1002/psc.340
Holband, J, Wojcik, G, Ziora, Z and Kafarski, P (2001). Conformational polymorphism of diethyl 1-(phthalylglycyloxy)-2-phthalylaminoethenephosphonate. Journal of Molecular Structure, 595 (1-3), 167-174. doi: 10.1016/S0022-2860(01)00521-X
Jedrzejczyk, D, Ziora, Z and Kafarski, P (2000). H-1 NMR studies of rotational isomerism in phosphonic analogues of aspartic acid. Magnetic Resonance in Chemistry, 38 (5), 370-374. doi: 10.1002/1097-458x(200005)38:5<370::aid-mrc651>3.0.co;2-m
Ziora, Zyta, Maly, Alina, Lejczak, Barbara, Kafarski, Pawel, Holband, Jolanta and W�jcik, Gra?yna (2000). Reactions of N-phthalylamino acid chlorides with trialkyl phosphites. Heteroatom Chemistry, 11 (3), 232-239. doi: 10.1002/(sici)1098-1071(2000)11:3<232::aid-hc12>3.0.co;2-u
Ziora, Z, Cierpicki, T, Grembecka, J and Kafarski, P (1999). Synthesis of triethyl N-formyl-N-phosphonomethylglycinate and diethyl N-formyl-N- phosphonomethylglycine and studies of their rotational conformers by dynamic NMR. Journal of Chemical Research (2), 68-69A. doi: 10.1039/a806474a
Ziora, Zyta, Maly, Alina, Lejczak, Barbara and Kafarski, Paweł (1999). Reaction of N-Phtalylamino Acid Chlorides with Trialkyl Phosphites. Phosphorus, Sulfur, and Silicon and the Related Elements, 147 (1), 145-145. doi: 10.1080/10426509908053553
Conference Papers
Skwarczynski, Mariusz, Liu, Tzu-Yu, Hussein, Waleed M., Jia, Zhongfan, Ziora, Zyta M., McMillan, Nigel A. J., Monteiro, Michael J. and Toth, Istvan (2014). Synthesis of therapeutic vaccine against cervical cancer. 4th Asia-Pacific International Peptide Symposium in conjunction with 50th Japanese Peptide Symposium, Osaka, Japan, 6-8 November 2013. Osaka, Japan: Japanese Peptide Society.
Gong, Y., Muldoon, C. A., Premraj, R., Ziora, Z. M., Bradford, T. A., Cheng, M., Ramu, S., Huang, J. X., Kavanagh, A., Pelingon, R., Lee, J. C., Wong, K., Butler, M. S., Blaskovich, M. A. and Cooper, M. A. (2012). New glycopeptidic antibiotics to combat multidrug resistant pathogens. 32nd European Peptide Symposium, Athens, Greece, 2-7 September 2012. Chichester, West Sussex, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.2449
Skwarczynski, M., Fuaad, A. A. H. A., Zaman, M., Jia, Z., Kowapradit, J., Rustanti, L., Ziora, Z. M., Monteiro, M. L. J., Batzloff, M. R., Goodc, M. F. and Toth, I. (2012). Nanoparticles-based peptide subunit vaccines against group A Streptococcus. 32nd European Peptide Symposium, Athens, Greece, 2-7 September 2012. Chichester, West Sussex, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.2448
Ziora, Zyta, Shuto, Daisuke, Kasai, Soko, Liu, Ping, Hidaka, Koushi, Igawa, Nagai, Nagamine, Ayaka, Stochaj, Monika, Hamada, Takashi, Kimura, Tooru, Hayashi, Yoshio and Kiso, Yoshiaki (2006). Modification of P4 position in beta-Secretase (BACE1) inhibitors containing phenylnorstatine. 42nd Japanese Peptide Symposium, Osaka, Japan, 27-29 October 2005. Osaka, Japan: Japanese Peptide Society.
Sohma, Youhei, Sasaki, Masato, Ziora, Zyta, Takahashi, N., Kimura, Tooru, Hayashi, Yoshio and Kiso, Yoshiaki (2004). A novel approach for the hydrophobic peptides synthesis and purification through O-N intramolecular acyl migration reaction. 18th American Peptide Symposium, Boston, MA, U.S.A., 19-23 July 2003. San Diego, CA, U.S.A.: American Peptide Society.