Skip to menu Skip to content Skip to footer
  • UQ Home
  • Contacts
  • Study
  • Maps
  • News
  • Events
  • Library
  • Give now
  • my.UQ
The University of Queensland
Institute for Molecular Bioscience Institute for Molecular Bioscience
Site search
Site search
Menu
  • Home
  • About
    • Our people
    • News and Features
      • Latest news
    • Major supporters
    • Governance
    • Diversity and Inclusion
    • Annual reports
    • Careers
  • Research
    • Researcher Leaders
    • Research Groups
    • Research Centres
    • Research Excellence
    • Research Impact
    • Research Community
  • Facilities
    • Microscopy
    • Nuclear Magnetic Resonance (NMR) Spectroscopy
    • Mass Spectrometry
    • IMB Sequencing Facility
    • Queensland Facility for Advanced Genome Editing
    • Queensland Facility for Advanced Bioinformatics (QFAB)
    • Queensland Emory Drug Discovery Initiative
    • Clive & Vera Ramaciotti Facility for Producing Pharmaceuticals in Plants
    • Centre for Solar Biotechnology Facility
  • Partner
  • Students
    • Why IMB
    • PhD
    • Masters by Research (MPhil)
    • Masters by Coursework
    • Honours
    • Undergraduate
    • Scholarships
    • Visiting Research Scholars
  • Get Involved
    • Events
    • Talks & Tours
    • Scientific artwork
    • Director's Circle
    • Citizen Science
    • Ambassadors
    • Newsletters
  • Give now
  • Contact

Dr Jennifer Deuis

NHMRC Early Career Fellow
Institute for Molecular Bioscience
+61 7 334 62366
j.deuis@uq.edu.au
View researcher profile
Dr Jennifer Deuis

Publications

Book Chapters (2)
Journal Articles (36)
Conference Papers (2)
Thesis (1)

Book Chapters

Israel, Mathilde R., Tay, Bryan, Deuis, Jennifer R. and Vetter, Irina (2017). Sodium channels and venom peptide pharmacology. In Advances in pharmacology: ion channels downunder (pp. 67-116) Cambridge, MA, United States: Academic Press. doi:10.1016/bs.apha.2017.01.004
Deuis, Jennifer, Vetter, Irina and Zimmermann, Katharina (2013). Characterizing response properties of cutaneous nociceptors using in vitro skin-nerve preparations. In Hermann Handwerker and Lars Arendt-nielsen (Ed.), Pain models: translational relevance and applications (pp. 33-46) Washington, United States: IASP Press.

Journal Articles

Mueller, Alexander, Starobova, Hana, Morgan, Michael, Dekan, Zoltan, Cheneval, Olivier, Schroeder, Christina I., Alewood, Paul F., Deuis, Jennifer R. and Vetter, Irina (2019) Antiallodynic effects of the selective NaV1.7 inhibitor Pn3a in a mouse model of acute postsurgical pain: evidence for analgesic synergy with opioids and baclofen. Pain, 160 8: 1766-1780. doi:10.1097/j.pain.0000000000001567
Starobova, Hana, Mueller, Alexander, Deuis, Jennifer R., Carter, David A. and Vetter, Irina (2019) Inflammatory and neuropathic gene expression signatures of chemotherapy-induced neuropathy induced by vincristine, cisplatin and oxaliplatin in C57BL/6J mice. The Journal of Pain, . doi:10.1016/j.jpain.2019.06.008
Israel, Mathilde R., Tanaka, Brian S., Castro, Joel, Thongyoo, Panumart, Robinson, Samuel D., Zhao, Peng, Deuis, Jennifer R., Craik, David J., Durek, Thomas, Brierley, Stuart M., Waxman, Stephen G, Dib-Hajj, Sulayman D. and Vetter, Irina (2019) NaV1.6 regulates excitability of mechanosensitive sensory neurons. Journal of Physiology, . doi:10.1113/JP278148
Mueller, Alexander, Starobova, Hana, Morgan, Michael, Dekan, Zoltan, Cheneval, Olivier, Schroeder, Christina I., Alewood, Paul F., Deuis, Jennifer R. and Vetter, Irina (2019) Anti-allodynic effects of the selective NaV1.7 inhibitor Pn3a in a mouse model of acute post-surgical pain: evidence for analgesic synergy with opioids and baclofen. Pain, . doi:10.1097/j.pain.0000000000001567
Tay, Bryan, Stewart, Teneale A., Davis, Felicity M., Deuis, Jennifer R. and Vetter, Irina (2019) Development of a high-throughput fluorescent no-wash sodium influx assay. PLOS One, 14 3: . doi:10.1371/journal.pone.0213751
Dash, Thomas S., Shafee, Thomas, Harvey, Peta J., Zhang, Chuchu, Peigneur, Steve, Deuis, Jennifer R., Vetter, Irina, Tytgat, Jan, Anderson, Marilyn A., Craik, David J., Durek, Thomas and Undheim, Eivind A. B. (2019) A centipede toxin family defines an ancient class of CSαβ defensins. Structure, 27 2: 315-326. doi:10.1016/j.str.2018.10.022
Yapa, Kunsala T. D. S., Deuis, Jennifer, Peters, Amelia A., Kenny, Paraic A., Roberts-Thomson, Sarah J., Vetter, Irina and Monteith, Gregory R. (2018) Assessment of the TRPM8 inhibitor AMTB in breast cancer cells and its identification as an inhibitor of voltage gated sodium channels. Life Sciences, 198 128-135. doi:10.1016/j.lfs.2018.02.030
Israel, Mathilde R., Morgan, Michael, Tay, Bryan and Deuis, Jennifer R. (2018) Toxins as tools: fingerprinting neuronal pharmacology. Neuroscience Letters, 679 4-14. doi:10.1016/j.neulet.2018.02.001
Morgan, Michael, Deuis, Jennifer R., Woodruff, Trent M., Lewis, Richard J. and Vetter, Irina (2018) Role of complement anaphylatoxin receptors in a mouse model of acute burn-induced pain. Molecular Immunology, 94 68-74. doi:10.1016/j.molimm.2017.12.016
Israel, Mathilde R., Thongyoo, Panumart, Deuis, Jennifer R., Craik, David J., Vetter, Irina and Durek, Thomas (2018) The E15R Point Mutation in Scorpion Toxin Cn2 Uncouples Its Depressant and Excitatory Activities on Human NaV1.6. Journal of Medicinal Chemistry, 61 4: 1730-1736. doi:10.1021/acs.jmedchem.7b01609
Muttenthaler, Markus, Andersson, Asa, Vetter, Irina, Menon, Rohit, Busnelli, Marta, Ragnarsson, Lotten, Bergmayr, Christian, Arrowsmith, Sarah, Deuis, Jennifer R., Chiu, Han Sheng, Palpant, Nathan J., O'Brien, Margaret, Smith, Terry J., Wray, Susan, Neumann, Inga D., Gruber, Christian W., Lewis, Richard J. and Alewood, Paul F. (2017) Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species. Science Signaling, 10 508: 1-13. doi:10.1126/scisignal.aan3398
Morgan, Michael, Deuis, Jennifer R., Frøsig-Jørgensen, Majbrit, Lewis, Richard J., Cabot, Peter J., Gray, Paul D. and Vetter, Irina (2017) Burn pain: a systematic and critical review of epidemiology, pathophysiology, and treatment. Pain Medicine, 19 4: 708-734. doi:10.1093/pm/pnx228
Sousa, Silmara R., Wingerd, Joshua S., Brust, Andreas, Bladen, Christopher, Ragnarsson, Lotten, Herzig, Volker, Deuis, Jennifer R., Dutertre, Sebastien, Vetter, Irina, Zamponi, Gerald W., King, Glenn F., Alewood, Paul F. and Lewis, Richard J. (2017) Discovery and mode of action of a novel analgesic β-toxin from the African spider Ceratogyrus darlingi. PLoS One, 12 9: e0182848. doi:10.1371/journal.pone.0182848
Deuis, Jennifer R., Dvorakova, Lucie S. and Vetter, Irina (2017) Methods used to evaluate pain behaviors in rodents. Frontiers in Molecular Neuroscience, 10 . doi:10.3389/fnmol.2017.00284
Dekan, Zoltan, Headey, Stephen J., Scanlon, Martin, Baldo, Brian A., Lee, Tzong-Hsien, Aguilar, Marie-Isabel, Deuis, Jennifer R., Vetter, Irina, Elliott, Alysha G., Amado, Maite, Cooper, Matthew A., Alewood, Dianne and Alewood, Paul F. (2017) Δ-Myrtoxin-Mp1a is a helical heterodimer from the venom of the jack jumper ant that has antimicrobial, membrane-disrupting, and nociceptive activities. Angewandte Chemie, 129 29: 8615-8619. doi:10.1002/ange.201703360
Dekan, Zoltan, Headey, Stephen J. , Scanlon, Martin, Baldo, Brian A. , Lee, Tzong-Hsien, Aguilar, Marie-Isabel, Deuis, Jennifer R. , Vetter, Irina, Elliott, Alysha G. , Amado, Maite, Cooper, Matthew A. , Alewood, Dianne and Alewood, Paul F. (2017) Δ-Myrtoxin-Mp1a is a helical heterodimer from the venom of the jack jumper ant that has antimicrobial, membrane-disrupting, and nociceptive activities. Angewandte Chemie, 56 29: 8495-8499. doi:10.1002/anie.201703360
Deuis, Jennifer R., Dekan, Zoltan, Wingerd, Joshua S., Smith, Jennifer J., Munasinghe, Nehan R., Bhola, Rebecca F., Imlach, Wendy L., Herzig, Volker, Armstrong, David A., Rosengren, K. Johan, Bosmans, Frank, Waxman, Stephen G., Dib-Hajj, Sulayman D., Escoubas, Pierre, Minett, Michael S., Christie, Macdonald J., King, Glenn F., Alewood, Paul F., Lewis, Richard J., Wood, John N. and Vetter, Irina (2017) Corrigendum: Pharmacological characterisation of the highly Na v 1.7 selective spider venom peptide Pn3a (Scientific Reports (2017) 7 (40883). Scientific Reports, 7 . doi:10.1038/srep46816
Cardoso, Fernanda Caldas, Dekan, Zoltan, Smith, Jennifer J., Deuis, Jennifer R., Vetter, Irina, Herzig, Volker, Alewood, Paul F., King, Glenn F and Lewis, Richard J. (2017) Modulatory features of the novel spider toxin μ-TRTX-Df1a isolated from the venom of the spider Davus fasciatus. British Journal of Pharmacology, 174 15: 2528-2544. doi:10.1111/bph.13865
Deuis, Jennifer R., Mueller, Alexander, Israel, Mathilde R. and Vetter, Irina (2017) The pharmacology of voltage-gated sodium channel activators. Neuropharmacology, 127 87-108. doi:10.1016/j.neuropharm.2017.04.014
Israel, Mathilde R., Tay, Bryan, Deuis, Jennifer R. and Vetter, Irina (2017) Sodium Channels and Venom Peptide Pharmacology. Advances in Pharmacology, 79 67-116. doi:10.1016/bs.apha.2017.01.004
Rahnama, Sassan, Deuis, Jennifer R., Cardoso, Fernanda C., Ramanujam, Venkatraman, Lewis, Richard J., Rash, Lachlan D., King, Glenn F., Vetter, Irina and Mobli, Mehdi (2017) The structure, dynamics and selectivity profile of a NaV 1.7 potency-optimised huwentoxin-IV variant. PLoS One, 12 3: e0173551. doi:10.1371/journal.pone.0173551
Inserra, Marco C., Isreal, Mathilde, Caldwell, Ashlee, Castro, Joel, Deuis, Jennifer R., Harrington, Andrea M., Keramidas, Angelo, Garcia-Caraballo, Sonia, Maddern, Jessica, Erickson, Andelain, Grundy, Luke, Rychkov, Grigori Y., Zimmerman, Katharina, Lewis, Richard J., Brierley, Stuart M. and Vetter, Irina (2017) Multiple sodium channel isoforms mediate the pathological effects of Pacific ciguatoxin-1. Scientific Reports, 7 1: 42810. doi:10.1038/srep42810
Deuis, Jennifer R., Dekan, Zoltan, Wingerd, Joshua S., Smith, Jennifer J., Munasinghe, Nehan R., Bhola, Rebecca F., Imlach, Wendy L., Herzig, Volker, Armstrong, David A., Rosengren, K. Johan, Bosmans, Frank, Waxman, Stephen G., Dib-Hajj, Sulayman D., Escoubas, Pierre, Minett, Michael S., Christie, Macdonald J., King, Glenn F., Alewood, Paul F., Lewis, Richard J., Wood, John N. and Vetter, Irina (2017) Pharmacological characterisation of the highly Nav1.7 selective spider venom peptide Pn3a. Scientific Reports, 7 1: 40883. doi:10.1038/srep40883
Deuis, Jennifer R., Yin, Kathleen, Cooper, Matthew A., Schroder, Kate and Vetter, Irina (2016) Role of NLRP3 inflammasome in a model of acute burn-induced pain. Burns, 43 2: 304-309. doi:10.1016/j.burns.2016.09.001
Vetter, Irina, Deuis, Jennifer, Mueller, Alexander, Israel, Mathilde R., Hana Starobova, Zhang, Alan, Rash, Lachlan D. and Mobli, Mehdi (2016) NaV1.7 as a pain target – from gene to pharmacology. Pharmacology and Therapeutics, 172 73-100. doi:10.1016/j.pharmthera.2016.11.015
Yang, Daryl C., Deuis, Jennifer R., Dashevsky, Daniel, Dobson, James, Jackson, Timothy N. W., Brust, Andreas, Xie, Bing, Koludarov, Ivan, Debono, Jordan, Hendrikx, Iwan, Hodgson, Wayne C., Josh, Peter, Nouwens, Amanda, Baillie, Gregory J., Bruxner, Timothy J. C., Alewood, Paul F., Peng Lim, Kelvin Kok, Frank, Nathaniel, Vetter, Irina and Fry, Bryan G. (2016) The snake with the scorpion's sting: novel three-finger toxin sodium channel activators from the venom of the long-glanded blue coral snake (Calliophis bivirgatus). Toxins, 8 10: 303. doi:10.3390/toxins8100303
Yin, Kathleen, Deuis, Jennifer R., Lewis, Richard J. and Vetter, Irina (2016) Transcriptomic and behavioural characterisation of a mouse model of burn pain identify the cholecystokinin 2 receptor as an analgesic target. Molecular Pain, 12 1-13. doi:10.1177/1744806916665366
Deuis, Jennifer R, Dekan, Zoltan, Inserra, Marco C., Lee, Tzong-Hsien, Aguilar, Marie-Isabel, Craik, David J., Lewis, Richard J., Alewood, Paul F., Mobli, Mehdi, Schroeder, Christina I., Henriques, Sónia Troeira and Vetter, Irina (2016) Development of a μO-conotoxin analogue with improved lipid membrane interactions and potency for the analgesic target NaV1.8. Journal of Biological Chemistry, 291 22: 11829-11842. doi:10.1074/jbc.M116.721662
Deuis, Jennifer R., Wingerd, Joshua S., Winter, Zoltan, Durek, Thomas, Dekan, Zoltan, Sousa, Silmara R., Zimmermann, Katharina, Hoffmann, Tali, Weidner, Christian, Nassar, Mohammed A., Alewood, Paul F., Lewis, Richard J. and Vetter, Irina (2016) Analgesic effects of GpTx-1, PF-04856264 and CNV1014802 in a mouse model of NaV1.7-Mediated pain. Toxins, 8 3: 78. doi:10.3390/toxins8030078
Deuis, Jennifer R. and Vetter, Irina (2016) The thermal probe test: a novel behavioral assay to quantify thermal paw withdrawal thresholds in mice. Temperature, 3 2: 199-207. doi:10.1080/23328940.2016.1157668
Deuis, Jennifer, Whately, Ella, Brust, Andreas, Inserra, Marco, Asvadi, Naghmeh Hajarol, Lewis, Richard J., Alewood, Paul F., Cabot, Peter J. and Vetter, Irina (2015) Activation of k opioid receptors in cutaneous nerve endings by conorphin-1, a novel subtype-selective conopeptide, does not mediate peripheral analgesia. ACS Chemical Neuroscience, 6 10: 1751-1758. doi:10.1021/acschemneuro.5b00113
Cardoso, Fernanda C., Deka, Zoltan, Rosengren, K. Johan, Erickson, Andelain, Vetter, Irina, Deuis, Jennifer R., Herzig, Volker, Alewood, Paul F., King, Glenn F. and Lewis, Richard J. (2015) Identification and characterization of ProTx-III [μ-TRTX-Tp1a], a new voltage-gated sodium channel inhibitor from venom of the tarantula Thrixopelma pruriens. Molecular Pharmacology, 88 2: 291-303. doi:10.1124/mol.115.098178
Mueller, Alexander, Starobova, Hana, Inserra, Marco C., Jin, Ai-Hua, Deuis, Jennifer R., Dutertre, Sebastien, Lewis, Richard J., Alewood, Paul F., Daly, Norelle L. and Vetter, Irina (2015) α-conotoxin MrIC is a biased agonist at α7 nicotinic acetylcholine receptors. Biochemical Pharmacology, 94 2: 155-163. doi:10.1016/j.bcp.2015.01.011
Deuis, Jennifer R., Lim, Yu Ling, Rodrigues de Sousa, Silmara, Lewis, Richard J., Alewood, Paul F., Cabot, Peter J. and Vetter, Irina (2014) Analgesic effects of clinically used compounds in novel mouse models of polyneuropathy induced by oxaliplatin and cisplatin. Neuro-Oncology, 16 10: 1324-1332. doi:10.1093/neuonc/nou048
Zimmermann, Katharina, Deuis, Jennifer R., Inserra, Marco C., Collins, Lindon S., Namer, Barbara, Cabot, Peter J., Reeh, Peter W., Lewis, Richard J. and Vetter, Irina (2013) Analgesic treatment of ciguatoxin-induced cold allodynia. Pain, 154 10: 1999-2006. doi:10.1016/j.pain.2013.06.015
Deuis, Jennifer R., Zimmermann, Katharina, Romanovsky, Andrej A., Possani, Lourival D., Cabot, Peter J., Lewis, Richard J. and Vetter, Irina (2013) An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Na(v)1.6 in peripheral pain pathways. Pain, 154 9: 1749-1757. doi:10.1016/j.pain.2013.05.032

Conference Papers

Schroeder, Christina I., Deuis, Jennifer, Henriques, Sonia Troeria, Dekan, Zoltan, Inserra, Marco, Mobli, Mehdi and Vetter, Irina (2016). Rational design and synthesis of a novel membrane binding NaV1.8 selective inhibitor with in vivo activity in pain models. In: 60th Annual Meeting of the Biophysical Society, Los Angeles, CA, United States, (33A-33A). 27 Feb - 2 Mar 2016. doi:10.1016/j.bpj.2015.11.247
Rahnama, S., Lachlan, R., Cardoso, F. C., Smith, J., Deuis, J., Vetter, I., King, G. F. and Mobli, M. (2015). Rational development of novel analgesics for the treatment of chronic pain: Structure-Function studies of an engineered Nav1.7 blocker. In: The 40th Lorne Conference on Protein Structure and Function, Lorne VIC, Australia, (). 8-12 February 2015.

Thesis

Deuis, Jennifer (2016). Using toxins to elucidate the role of voltage-gated sodium channels in pain PhD Thesis, School of Pharmacy, The University of Queensland. doi:10.14264/uql.2016.53
© The University of Queensland
Enquiries: +61 7 3365 1111   |   Contact directory
ABN: 63 942 912 684   |   CRICOS Provider No: 00025B
Emergency
Phone: 3365 3333
Privacy & Terms of use   |   Feedback   |   Updated: 9 Dec 2019
Login