Dr Johannes Zuegg

van Niekerk, Annick, Joseph, M. Cassiem, Kavanagh, Angela, Dinh, Hue, Swarts, Andrew J., Mapolie, Selwyn F., Zuegg, Johannes, Cain, Amy K., Elliott, Alysha G., Blaskovich, Mark A. T. and Frei, Angelo (2023). The antimicrobial properties of PdII‐ and RuII‐pyta complexes. ChemBioChem, 24 (19) e202300247, e202300247. doi: 10.1002/cbic.202300247

Frei, Angelo, Verderosa, Anthony D., Elliott, Alysha G., Zuegg, Johannes and Blaskovich, Mark A. T. (2023). Metals to combat antimicrobial resistance. Nature Reviews Chemistry, 7 (3), 1-23. doi: 10.1038/s41570-023-00463-4

Hart, Christopher J. S., Riches, Andrew G., Tiash, Snigdha, Clapper, Erin, Ramu, Soumya, Zuegg, Johannes, Ryan, John H. and Skinner-Adams, Tina S. (2022). A subset screen of the Compounds Australia Scaffold Library identifies 7-acylaminodibenzoxazepinones as potent and selective hits for anti-Giardia drug discovery. Biomedicines, 10 (12) 3182, 1-14. doi: 10.3390/biomedicines10123182

Blaskovich, Mark A.T., Hansford, Karl A., Butler, Mark S., Ramu, Soumya, Kavanagh, Angela M., Jarrad, Angie M., Prasetyoputri, Anggia, Pitt, Miranda E., Huang, Johnny X., Lindahl, Fredrik, Ziora, Zyta M., Bradford, Tanya, Muldoon, Craig, Rajaratnam, Premraj, Pelingon, Ruby, Edwards, David J., Zhang, Bing, Amado, Maite, Elliott, Alysha G., Zuegg, Johannes, Coin, Lachlan, Woischnig, Anne-Kathrin, Khanna, Nina, Breidenstein, Elena, Stincone, Anna, Mason, Clive, Khan, Nawaz, Cho, Hye-Kyung, Karau, Melissa J. ... Cooper, Matthew A. (2022). A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections. Science Translational Medicine, 14 (662) abj2381. doi: 10.1126/scitranslmed.abj238

Blaskovich, Mark A.T., Hansford, Karl A., Butler, Mark S., Ramu, Soumya, Kavanagh, Angela M., Jarrad, Angie M., Prasetyoputri, Anggia, Pitt, Miranda E., Huang, Johnny X., Lindahl, Fredrik, Ziora, Zyta M., Bradford, Tanya, Muldoon, Craig, Rajaratnam, Premraj, Pelingon, Ruby, Edwards, David J., Zhang, Bing, Amado, Maite, Elliott, Alysha G., Zuegg, Johannes, Coin, Lachlan, Woischnig, Anne-Kathrin, Khanna, Nina, Breidenstein, Elena, Stincone, Anna, Mason, Clive, Khan, Nawaz, Cho, Hye-Kyung, Karau, Melissa J. ... Cooper, Matthew A. (2022). A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections. Science Translational Medicine, 14 (662) abj2381, 1-16. doi: 10.1126/scitranslmed.abj2381

Medina-Franco, José L., López-López, Edgar, Andrade, Emma, Ruiz-Azuara, Lena, Frei, Angelo, Guan, Davy, Zuegg, Johannes and Blaskovich, Mark A.T. (2022). Bridging informatics and medicinal inorganic chemistry: toward a database of metallodrugs and metallodrug candidates. Drug Discovery Today, 27 (5), 1420-1430. doi: 10.1016/j.drudis.2022.02.021

Baker, Jennifer R., Cossar, Peter J., Blaskovich, Mark A. T., Elliott, Alysha G., Zuegg, Johannes, Cooper, Matthew A., Lewis, Peter J. and McCluskey, Adam (2022). Amino alcohols as potential antibiotic and antifungal leads. Molecules, 27 (7) 2050, 2050. doi: 10.3390/molecules27072050

König, Gerhard, Sokkar, Pandian, Pryk, Niclas, Heinrich, Sascha, Möller, David, Cimicata, Giuseppe, Matzov, Donna, Dietze, Pascal, Thiel, Walter, Bashan, Anat, Elisabeth Bandow, Julia, Zuegg, Johannes, Yonath, Ada, Schulz, Frank and Sanchez-Garcia, Elsa (2021). Rational prioritization strategy allows the design of macrolide derivatives that overcome antibiotic resistance. Proceedings of the National Academy of Sciences of the United States of America, 118 (46) e2113632118. doi: 10.1073/pnas.2113632118

Demchenko, Sergii, Lesyk, Roman, Yadlovskyi, Oleh, Zuegg, Johannes, Elliott, Alysha G., Drapak, Iryna, Fedchenkova, Yuliia, Suvorova, Zinaida and Demchenko, Anatolii (2021). Synthesis, antibacterial and antifungal activity of new 3-Aryl-5H-pyrrolo[1,2-a]imidazole and 5H-Imidazo[1,2-a]azepine quaternary salts. Molecules, 26 (14) 4253, 1-13. doi: 10.3390/molecules26144253

Semenov, Victor V., Raihstat, Mikhail M., Konyushkin, Leonid D., Semenov, Roman V., Blaskovich, Mark A. T., Zuegg, Johannes, Elliott, Alysha G., Hansford, Karl A. and Cooper, Matthew A. (2021). Antimicrobial screening of a historical collection of over 140 000 small molecules. Mendeleev Communications, 31 (4), 484-487. doi: 10.1016/j.mencom.2021.07.015

Frei, Angelo, King, A. Paden, Lowe, Gabrielle J., Cain, Amy K., Short, Francesca L., Dinh, Hue, Elliott, Alysha G., Zuegg, Johannes, Wilson, Justin J. and Blaskovich, Mark A. T. (2021). Nontoxic cobalt(III) schiff base complexes with broad‐spectrum antifungal activity. Chemistry – A European Journal, 27 (6), 2021-2029. doi: 10.1002/chem.202003545

Frei, Angelo, King, A. Paden, Lowe, Gabrielle J., Cain, Amy K., Short, Francesca L., Dinh, Hue, Elliott, Alysha G., Zuegg, Johannes, Wilson, Justin J. and Blaskovich, Mark A. T. (2021). Cover feature: nontoxic cobalt(III) schiff base complexes with broad‐spectrum antifungal activity (Chem. Eur. J. 6/2021). Chemistry – A European Journal, 27 (6), 1861-1861. doi: 10.1002/chem.202004912

Blaskovich, Mark A. T., Kavanagh, Angela M., Elliott, Alysha G., Zhang, Bing, Ramu, Soumya, Amado, Maite, Lowe, Gabrielle J., Hinton, Alexandra O., Pham, Do Minh Thu, Zuegg, Johannes, Beare, Neil, Quach, Diana, Sharp, Marc D., Pogliano, Joe, Rogers, Ashleigh P., Lyras, Dena, Tan, Lendl, West, Nicholas P., Crawford, David W., Peterson, Marnie L., Callahan, Matthew and Thurn, Michael (2021). The antimicrobial potential of cannabidiol. Communications Biology, 4 (1) 7, 1-18. doi: 10.1038/s42003-020-01530-y

Frei, Angelo, Ramu, Soumya, Lowe, Gabrielle J., Dinh, Hue, Semenec, Lucie, Elliott, Alysha G., Zuegg, Johannes, Deckers, Anke, Jung, Nicole, Bräse, Stefan, Cain, Amy K. and Blaskovich, Mark A. T. (2021). Platinum cyclooctadiene complexes with activity against gram-positive bacteria. ChemMedChem, 16 (20) cmdc.202100157, 1-8. doi: 10.1002/cmdc.202100157

Fuller, Amelia A., Dounay, Amy B., Schirch, Douglas, Rivera, Daniel G., Hansford, Karl A., Elliott, Alysha G., Zuegg, Johannes, Cooper, Matthew A., Blaskovich, Mark A. T., Hitchens, Jacob R., Burris-Hiday, Sarah, Tenorio, Kristiana, Mendez, Yanira, Samaritoni, J. Geno, O’Donnell, Martin J. and Scott, William L. (2020). Multi-institution research and education collaboration identifies new antimicrobial compounds. ACS Chemical Biology, 15 (12), 3187-3196. doi: 10.1021/acschembio.0c00732

Pamarthi, Rambabu, Kumar, Ram, Sankara, Chennikkayala Siva, Lowe, Gabrielle J., Zuegg, Johannes, Singh, Sudheer Kumar and Ganesh, Madhu (2020). α-Iodonitroalkenes as potential antifungal and antitubercular agents. ChemistrySelect, 5 (39), 12272-12277. doi: 10.1002/slct.202003251

Demchenko, Sergii, Lesyk, Roman, Zuegg, Johannes, Elliott, Alysha G., Fedchenkova, Yuliia, Suvorova, Zinaida and Demchenko, Anatolii (2020). Synthesis, antibacterial and antifungal activity of new 3-biphenyl-3H-Imidazo[1,2-a]azepin-1-ium bromides. European Journal of Medicinal Chemistry, 201 112477, 112477. doi: 10.1016/j.ejmech.2020.112477

Elliott, Alysha G., Huang, Johnny X., Neve, Søren, Zuegg, Johannes, Edwards, Ingrid A., Cain, Amy K., Boinett, Christine J., Barquist, Lars, Lundberg, Carina Vingsbo, Steen, Jason, Butler, Mark S., Mobli, Mehdi, Porter, Kaela M., Blaskovich, Mark A. T., Lociuro, Sergio, Strandh, Magnus and Cooper, Matthew A. (2020). An amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteria. Nature Communications, 11 (1) 3184, 3184. doi: 10.1038/s41467-020-16950-x

Zuegg, Johannes, Hansford, Karl A., Elliott, Alysha G., Cooper, Matthew A. and Blaskovich, Mark A. T. (2020). How to stimulate and facilitate early stage antibiotic discovery. ACS Infectious Diseases, 6 (6), 1302-1304. doi: 10.1021/acsinfecdis.0c00163

Frei, Angelo, Zuegg, Johannes, Elliott, Alysha G., Baker, Murray, Braese, Stefan, Brown, Christopher, Chen, Feng, Dowson, Christopher G., Dujardin, Gilles, Jung, Nicole, King, A. Paden, Mansour, Ahmed M., Massi, Massimiliano, Moat, John, Mohamed, Heba A., Renfrew, Anna K., Rutledge, Peter J., Sadler, Peter J., Todd, Matthew H., Willans, Charlotte E., Wilson, Justin J., Cooper, Matthew A. and Blaskovich, Mark A. T. (2020). Correction: Metal complexes as a promising source for new antibiotics (vol 11, pg 2627, 2020). Chemical Science, 11 (17), 4531-4531. doi: 10.1039/d0sc90075c

Rineh, Ardeshir, Soren, Odel, McEwan, Timothy, Ravikumar, Vikashini, Poh, Wee Han, Azamifar, Fereshteh, Naimi-Jamal, M. Reza, Cheung, Chen-Yi, Elliott, Alysha G., Zuegg, Johannes, Blaskovich, Mark A. T., Cooper, Matthew A., Dolange, Victoria, Christodoulides, Myron, Cook, Gregory M., Rice, Scott A., Faust, Saul N., Webb, Jeremy S. and Kelso, Michael J. (2020). Discovery of cephalosporin-3′-diazeniumdiolates that show dual antibacterial and antibiofilm effects against Pseudomonas aeruginosa clinical cystic fibrosis isolates and efficacy in a murine respiratory infection model. ACS Infectious Diseases, 6 (6) acsinfecdis.0c00070, 1460-1479. doi: 10.1021/acsinfecdis.0c00070

Frei, Angelo, Zuegg, Johannes, Elliott, Alysha G., Baker, Murray V., Braese, Stefan, Brown, Christopher, Chen, Feng, Dowson, Christopher Gerard, Dujardin, Gilles, Jung, Nicole, King, A. Paden, Mansour, Ahmed Moustafa, Massi, Massimiliano, Moat, John, Mohamed, Heba A., Renfrew, Anna, Rutledge, Peter, Sadler, Peter J., Todd, Matthew Houghton, Willans, Charlotte E., Wilson, Justin Jeff, Cooper, Matthew Allister and Blaskovich, Mark (2020). Metal complexes as a promising source for new antibiotics. Chemical Science, 11 (10), 2627-2639. doi: 10.1039/c9sc06460e

Nazir, Yasir, Saeed, Aamer, Rafiq, Muhammad, Afzal, Samina, Ali, Anser, Latif, Muhammad, Zuegg, Johannes, Hussein, Waleed M., Fercher, Christian, Barnard, Ross T., Cooper, Matthew A., Blaskovich, Mark A.T., Ashraf, Zaman and Ziora, Zyta M. (2020). Hydroxyl substituted benzoic acid/cinnamic acid derivatives: tyrosinase inhibitory kinetics, anti-melanogenic activity and molecular docking studies. Bioorganic and Medicinal Chemistry Letters, 30 (1) 126722, 1-5. doi: 10.1016/j.bmcl.2019.126722

Overman, Jeroen, Fontaine, Frank, Wylie-Sears, Jill, Moustaqil, Mehdi, Huang, Lan, Meurer, Marie, Chiang, Ivy Kim, Lesieur, Emmanuelle, Patel, Jatin, Zuegg, Johannes, Pasquier, Eddy, Sierecki, Emma, Gambin, Yann, Hamdan, Mohamed, Khosrotehrani, Kiarash, Andelfinger, Gregor, Bischoff, Joyce and Francois, Mathias (2019). R-propranolol is a small molecule inhibitor of the SOX18 transcription factor in a rare vascular syndrome and hemangioma. eLife, 8 e43026. doi: 10.7554/elife.43026

Rao, Madhuri P., Gunaga, Shubha S., Zuegg, Johannes, Pamarthi, Rambabu and Ganesh, Madhu (2019). Highly regio- and diastereoselective [3 + 2]-cycloadditions involving indolediones and α,β-disubstituted nitroethylenes. Organic and Biomolecular Chemistry, 17 (42), 9390-9402. doi: 10.1039/c9ob01429b

Fontaine, Frank R., Goodall, Stephen, Prokop, Jeremy W., Howard, Christopher B., Moustaqil, Mehdi, Kumble, Sumukh, Rasicci, Daniel T., Osborne, Geoffrey W., Gambin, Yann, Sierecki, Emma, Jones, Martina L., Zuegg, Johannes, Mahler, Stephen and Francois, Mathias (2018). Functional domain analysis of SOX18 transcription factor using a single-chain variable fragment-based approach. mAbs, 10 (4), 1-11. doi: 10.1080/19420862.2018.1451288

Blaskovich, Mark A T, Hansford, Karl A., Gong, Yujing, Butler, Mark S., Muldoon, Craig, Huang, Johnny X., Ramu, Soumya, Silva, Alberto B., Cheng, Mu, Kavanagh, Angela M., Ziora, Zyta, Premraj, Rajaratnam, Lindahl, Fredrik, Bradford, Tanya A., Lee, June C., Karoli, Tomislav, Pelingon, Ruby, Edwards, David J., Amado, Maite, Elliott, Alysha G, Phetsang, Wanida, Daud, Noor Huda, Deecke, Johan E, Sidjabat, Hanna E, Ramaologa, Sefetogi, Zuegg, Johannes, Betley, Jason R, Beevers, Andrew P G, Smith, Richard A G ... Cooper, Matthew A. (2018). Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria. Nature Communications, 9 (1) 02123, 22. doi: 10.1038/s41467-017-02123-w

Scott, Fraser J., Nichol, Ryan J. O., Khalaf, Abedawn I., Giordani, Federica, Gillingwater, Kirsten, Ramu, Soumya, Elliott, Alysha, Zuegg, Johannes, Duffy, Paula, Rosslee, Michael-Jon, Hlaka, Lerato, Kumar, Santosh, Ozturk, Mumin, Brombacher, Frank, Barrett, Michael, Guler, Reto and Suckling, Colin J. (2017). An evaluation of Minor Groove Binders as anti-fungal and anti-mycobacterial therapeutics. European Journal of Medicinal Chemistry, 136, 561-572. doi: 10.1016/j.ejmech.2017.05.039

Desselle, Mathilde R., Neale, Ruth, Hansford, Karl A., Zuegg, Johannes, Elliott, Alysha G., Cooper, Matthew A. and Blaskovich, Mark A. T. (2017). Institutional profile: Community for Open Antimicrobial Drug Discovery - crowdsourcing new antibiotics and antifungals. Future Science OA, 3 (2) FSO171, FSO171. doi: 10.4155/fsoa-2016-0093

Fontaine, Frank, Overman, Jeroen, Moustaqil, Mehdi, Mamidyala, Sreeman, Salim, Angela, Narasimhan, Kamesh, Prokoph, Nina, Robertson, Avril A. B., Lua, Linda, Alexandrov, Kirill, Koopman, Peter, Capon, Robert J., Sierecki, Emma, Gambin, Yann, Jauch, Ralf, Cooper, Matthew A., Zuegg, Johannes and Francois, Mathias (2017). Small-molecule inhibitors of the SOX18 transcription factor. Chemistry Chemical Biology, 24 (3), 346-359. doi: 10.1016/j.chembiol.2017.01.003

Edwards, Ingrid A., Elliott, Alysha G., Kavanagh, Angela M., Zuegg, Johannes, Blaskovich, Mark A. T. and Cooper, Matthew A. (2016). Contribution of amphipathicity and hydrophobicity to the antimicrobial activity and cytotoxicity of β‑hairpin peptides. ACS Infectious Diseases, 2 (6), 442-450. doi: 10.1021/acsinfecdis.6b00045

Mesleh, Michael F., Rajaratnam, Premraj, Conrad, Mary, Chandrasekaran, Vasu, Liu, Christopher M., Pandya, Bhaumik A., Hwang, You Seok, Rye, Peter T., Muldoon, Craig, Becker, Bernd, Zuegg, Johannes, Meutermans, Wim and Moy, Terence I. (2016). Targeting bacterial cell wall peptidoglycan synthesis by inhibition of glycosyltransferase activity. Chemical Biology and Drug Design, 87 (2), 190-199. doi: 10.1111/cbdd.12662

Jarrad, Angie M., Karoli, Tomislav, Anjan, Debnath, Tay, Chin Yen, Huang, Johnny X., Kaeslin, Geraldine, Elliott, Alysha G., Miyamoto, Yukiko, Ramu, Soumya, Kavanagh, Angela M., Zuegg, Johannes, Eckmann, Lars, Blaskovich, Mark A. and Cooper, Matthew A. (2015). Metronidazole-triazole conjugates: activity against Clostridium difficile and parasites. European Journal of Medicinal Chemistry, 101 7946, 96-102. doi: 10.1016/j.ejmech.2015.06.019

Zuegg, Johannes, Muldoon, Craig, Adamson, George, McKeveney, Declan, Le Thanh, Giang, Premraj, Rajaratnam, Becker, Bernd, Cheng, Mu, Elliott, Alysha G., Huang, Johnny X., Butler, Mark S., Bajaj, Megha, Seifert, Joachim, Singh, Latika, Galley, Nicola F., Roper, David I., Lloyd, Adrian J., Dowson, Christopher G., Cheng, Ting-Jen, Cheng, Wei-Chieh, Demon, Dieter, Meyer, Evelyne, Meutermans, Wim and Cooper, Matthew A. (2015). Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity. Nature Communications, 6 (1) 7719, 1-11. doi: 10.1038/ncomms8719

Blaskovich, Mark A. T., Zuegg, Johannes, Elliott, Alysha G. and Cooper, Matthew (2015). Helping chemists discover new antibiotics. ACS Infectious Diseases, 1 (7), 285-287. doi: 10.1021/acsinfecdis.5b00044

Bajaj, Megha, Mamidyala, Sreeman K., Zuegg, Johannes, Begg, Stephanie L., Ween, Miranda P., Luo, Zhenyao, Huang, Johnny Xiao, McEwan, Alastair G., Kobe, Bostjan, Paton, James C., McDevitt, Christopher A. and Cooper, Matthew A. (2015). Discovery of novel pneumococcal surface antigen A (PsaA) inhibitors using a fragment-based drug design approach. ACS Chemical Biology, 10 (6), 1511-1520. doi: 10.1021/cb501032x

Zuegg, Johannes (2015). Neue Strukturen für Antibiotika gesucht. Nachrichten aus der Chemie, 63 (11), 1101-1103. doi: 10.1002/nadc.201590371

Phetsang, Wanida, Blaskovich, Mark A. T., Butler, Mark S., Huang, Johnny Xiao, Zuegg, Johannes, Mamidyala, Sreeman K., Ramu, Soumya, Kavanagh, Angela M. and Cooper, Matthew A. (2014). An azido-oxazolidinone antibiotic for live bacterial cell imaging and generation of antibiotic variants. Bioorganic and Medicinal Chemistry, 22 (16), 4490-4498. doi: 10.1016/j.bmc.2014.05.054

Couñago, Rafael M., Ween, Miranda P., Begg, Stephanie L., Bajaj, Megha, Zuegg, Johannes, O'Mara, Megan L., Cooper, Matthew A., McEwan, Alastair G., Paton, James C., Kobe, Bostjan and McDevitt, Christopher A. (2014). Imperfect coordination chemistry facilitates metal ion release in the Psa permease. Nature Chemical Biology, 10 (1), 35-41. doi: 10.1038/nCHeMBIO.1382

Jia, ZhiGuang, O'Mara, Megan L., Zuegg, Johannes, Cooper, Matthew A. and Mark, Alan E. (2013). Vancomycin: ligand recognition, dimerization and super-complex formation. FEBS Journal, 280 (5), 1294-1307. doi: 10.1111/febs.12121

Jia, Z. G., O'Mara, M. L., Zuegg, J., Matthew Cooper and Mark, Alan (2013). Erratum: The effect of environment on the recognition and binding of vancomycin to native and resistant forms of lipid II (Biophysical Journal (2011) 101 (2684-2692)). Biophysical Journal, 104 (2), 516-516. doi: 10.1016/j.bpj.2012.12.031

Novoa, Alexandre, Van Dorpe, Sylvia, Wynendaele, Evelien, Spetea, Mariana, Bracke, Nathalie, Stalmans, Sofie, Betti, Cecilia, Chung, Nga N., Lemieux, Carole, Zuegg, Johannes, Cooper, Matthew A., Tourwe, Dirk, De Spiegeleer, Bart, Schiller, Peter W. and Ballet, Steven (2012). Variation of the net charge, lipophilicity, and side chain flexibility in Dmt(1)-DALDA: effect on opioid activity and biodistribution. Journal of Medicinal Chemistry, 55 (22), 9549-9561. doi: 10.1021/jm3008079

Karoli, Tomislav, Becker, Bernd, Zuegg, Johannes, Moellmann, Ute, Ramu, Soumya, Huang, Johnny X. and Cooper, Matthew A. (2012). Identification of antitubercular benzothiazinone compounds by ligand-based design. Journal of Medicinal Chemistry, 55 (17), 7940-7944. doi: 10.1021/jm3008882

Zuegg, Johannes and Cooper, Matthew A. (2012). Drug-likeness and increased hydrophobicity of commercially available compound libraries for drug screening. Current Topics in Medicinal Chemistry, 12 (14), 1500-1513. doi: 10.2174/156802612802652466

Karoli, Tomislav, Mamidyala, Sreeman K., Zuegg, Johannes, Fry, Scott R., Tee, Ernest H. L., Bradford, Tanya A., Madala, Praveen K., Huang, Johnny X., Ramu, Soumya, Butler, Mark S. and Cooper, Matthew A. (2012). Structure aided design of chimeric antibiotics. Bioorganic & Medicinal Chemistry Letters, 22 (7), 2428-2433. doi: 10.1016/j.bmcl.2012.02.019

Jia, ZhiGuang, O'Mara, Megan L., Zuegg, Johannes, Cooper, Matthew A. and Mark, Alan E. (2011). The effect of environment on the recognition and binding of vancomycin to native and resistant forms of lipid II. Biophysical Journal, 101 (11), 2684-2692. doi: 10.1016/j.bpj.2011.10.047

Abbenante, Giovanni, Becker, Bernd, Blanc, Sebastien, Clark, Chris, Condie, Glenn, Fraser, Graeme, Grathwohl, Matthias, Halliday, Judy, Henderson, Senka, Lam, Ann, Liu, Ligong, Mann, Maretta, Muldoon, Craig, Pearson, Andrew, Premraj, Rajaratnam, Ramsdale, Tracie, Rossetti, Tony, Schafer, Karl, Le Thanh, Giang, Tometzki, Gerald, Vari, Frank, Verquin, Geraldine, Waanders, Jennifer, West, Michael, Wimmer, Norbert, Yau, Annika, Zuegg, Johannes and Meutermans, Wim (2010). Biological diversity from a structurally diverse library: Systematically scanning conformational space using a pyranose scaffold. Journal of Medicinal Chemistry, 53 (15), 5576-5586. doi: 10.1021/jm1002777

Thanh, Giang Le, Abbenante, Giovanni, Adamson, George, Becker, Bernd, Clark, Chris, Condie, Glenn, Falzun, Tania, Grathwohl, Matthias, Gupta, Praveer, Hanson, Michael, Huynh, Ngoc, Katavic, Peter, Kuipers, Krystle, Lam, Ann, Liu, Ligong, Mann, Maretta, Mason, Jeff, McKeveney, Declan, Muldoon, Craig, Pearson, Andrew, Rajaratnam, Premraj, Ryan, Sarah, Tometzki, Gerry, Verquin, Geraldine, Waanders, Jennifer, West, Michael, Wilcox, Neil, Wimmer, Norbert, Yau, Annika ... Meutermans, Wim (2010). A versatile synthetic approach toward diversity libraries using monosaccharide scaffolds. Journal of Organic Chemistry, 75 (1), 197-203. doi: 10.1021/jo9021919

Zuegg, Johannes and Meutermans, Wim (2007). Crystal structures of the PBP2 glycosyltransferase domain: For antibacterial drug design new opportunities. Chemmedchem, 2 (10), 1403-1404. doi: 10.1002/cmdc.200700114

Pham T.D. and Zuegg J. (2004). A probabilistic measure for alignment-free sequence comparison. Bioinformatics, 20 (18), 3455-3461. doi: 10.1093/bioinformatics/bth426

Zuegg, J, Bliznyuk, AA and Gready, JE (2003). Comparison of electrostatic potential around proteins calculated from Amber and AM1 charges: application to mutants of prion protein. Molecular Physics, 101 (15), 2437-2450. doi: 10.1080/00268970310001592737

Le, GT, Abbenante, G, Becker, B, Grathwohl, M, Halliday, J, Tometzki, G, Zuegg, J and Meutermans, W (2003). Molecular diversity through sugar scaffolds. Drug Discovery Today, 8 (15), 701-709. doi: 10.1016/S1359-6446(03)02751-X

Zuegg, J., Webb, D. C., Foster, P. S. and Casarotto, M. G. (2001). Structural model of human IL-13 defines the spatial interactions with the IL-13Rα/IL-4Rα receptor. Immunology and Cell Biology, 79 (4), 332-339. doi: 10.1046/j.1440-1711.2001.01035.x

Hulett M.D., Hornby J.R., Ohms S.J., Zuegg J., Freeman C., Gready J.E. and Parish C.R. (2000). Identification of active-site residues of the pro-metastatic endoglycosidase heparanase. Biochemistry, 39 (51), 15659-15667. doi: 10.1021/bi002080p

Zuegg, J and Gready, JE (2000). Molecular dynamics simulation of human prion protein including both N-linked oligosaccharides and the GPI anchor. Glycobiology, 10 (10), 959-974. doi: 10.1093/glycob/10.10.959

Zuegg J. and Gready J.E. (1999). Molecular dynamics simulations of human prion protein: Importance of correct treatment of electrostatic interactions. Biochemistry, 38 (42), 13862-13876. doi: 10.1021/bi991469d

Zuegg, J, Gruber, K, Gugganig, M, Wagner, UG and Kratky, C (1999). Three-dimensional structures of enzyme-substrate complexes of the hydroxynitrile lyase from Hevea brasiliensis. Protein Science, 8 (10), 1990-2000. doi: 10.1110/ps.8.10.1990

Zuegg J., Honig H., Schrag J.D. and Cygler M. (1997). Selectivity of lipases: Conformational analysis of suggested intermediates in ester hydrolysis of chiral primary and secondary alcohols. Journal of Molecular Catalysis - B Enzymatic, 3 (1-4), 83-98. doi: 10.1016/S1381-1177(96)00060-4

Weber H.K., Zuegg J., Faber K. and Pleiss J. (1997). Molecular reasons for lipase-sensitivity against acetaldehyde. Journal of Molecular Catalysis - B Enzymatic, 3 (1-4), 131-138. doi: 10.1016/S1381-1177(96)00045-8

Petersen, EI, Zuegg, J, Ribbons, DW and Schwab, H (1996). Molecular cloning and homology modeling of protocatechuate 3,4-dioxygenase from Pseudomonas marginata. Microbiological Research, 151 (4), 359-370. doi: 10.1016/S0944-5013(96)80004-8

Faber, K, Griengl, H, Honig, H and Zuegg, J (1994). On the Prediction of the Enantioselectivity of Candida-Rugosa Lipase by Comparative Molecular-Field Analysis. Biocatalysis, 9 (1-4), 227-239. doi: 10.3109/10242429408992122

Martl, MG, Zuegg, J and Hummel, K (1991). Improved Computer-Simulation of Metathesis Reactions. Journal of Molecular Catalysis, 65 (1-2), 127-138. doi: 10.1016/0304-5102(91)85089-K

Chia, C. S. Brian, Gong, Yujing, Bowie, John H., Zuegg, Johannes and Cooper, Matthew A. (2011). Membrane binding and perturbation studies of the antimicrobial peptides caerin, citropin and maculatin. New York, NY, U.S.A.: John Wiley & Sons. doi: 10.1002/bip.21438

Adamson, G, Schafer, K, Louis, L, Tometzki, G, Le Thanh, G, Schliebs, D, West, M, Zuegg, J, Halliday, J and Meutermans, W (2001). Carbohydrate-based combinatorial libraries for the discovery of new antibacterial agents. CARY: OXFORD UNIV PRESS INC.

Francois, Mathias, Zuegg, Johannes, Overman, Jeroen, Mamidyala, Sreeman Kumar, Salim, Angela Aguslyarti, Fontaine, Frank Roger, Cooper, Matthew Allister, Capon, Robert John and Robertson, Avril Alexis Barbara (2017). Inhibitors of SOX 18 protein activity for treating angiogenesis- and/or lymphangiogenesis. WO2018112545.

Tometzki, Gerald B., Meutermans, Wim, Becker, Bernd, Zuegg, Johannes, Premraj, Rajaratnam, Muldoon, Craig, Mckeveney, Declan and Condie, Glenn (2008). Selective Inhibitors. US 20080009418.

Meutermans, Wim, Mckeveney, Declan, Zuegg, Johannes, Premraj, Rajaratnam, Muldoon, Craig and Le Thanh, Giang (2007). Monosaccharide compounds as antibacterial agents and their preparation and use in the treatment of diseases.

Becker, Bernd, Condie, Glenn, Christopher, McKeveney, Declan, Meutermans, Wim, Muldoon, Craig, Premraj, Rajaratnam and Zuegg, Johannes (2006). Selective inhibitors. WO/2006/037159; PCT/AU2005/001510.

Becker, Bernd, Condie, Glenn, Halliday, Judy, McKeveney, Declan, Meutermans, Wim, Muldoon, Craig, Premraj, Rajaratnam, Ramsdale, Tracie Elizabeth, Tometzki, Gerald and Zuegg, Johannes (2005). Biologically active compounds with with anti-angiogenic properties. WO/2005/097142; PCT/AU2005/000506.

Dr Johannes Zuegg

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