Journal Articles
Sato, Kei, See Hoe, Louise, Chan, Jonathan, Obonyo, Nchafatso G., Wildi, Karin, Heinsar, Silver, Colombo, Sebastiano M., Ainola, Carmen, Abbate, Gabriella, Sato, Noriko, Passmore, Margaret R., Bouquet, Mahe, Wilson, Emily S., Hyslop, Kieran, Livingstone, Samantha, Haymet, Andrew, Jung, Jae‐Seung, Skeggs, Kris, Palmieri, Chiara, White, Nicole, Platts, David, Suen, Jacky Y., McGiffin, David C., Li Bassi, Gianluigi and Fraser, John F. (2024). Echocardiographic surrogate of left ventricular stroke work in a model of brain stem death donors. European Journal of Clinical Investigation, 54 (10) e14259. doi: 10.1111/eci.14259
Nonaka, Hideaki, Liu, Keibun, Milani, Angelo, Fior, Gabriele, Hoshino, Kota, Obonyo, Nchafatso, Portatadino, Sofia, Abbate, Gabriella, Panduru, Rachana, McInerney, Molly-Rose, Passmore, Margaret, Li Bassi, Gianluigi, Suen, Jacky and Fraser, John F (2024). 164: Development of Right Ventricular Dysfunction Induced by Respiratory Failure: Insights from an Ovine Model of Acute Respiratory Distress Syndrome and Veno-Venous Extracorporeal Membrane Oxygenation. ASAIO Journal, 70 (Supplement 4), 55-55. doi: 10.1097/01.mat.0001070112.10477.fa
Sato, Kei, Heinsar, Silver, Chan, Jonathan, Farah, Samia M., Wildi, Karin, Obonyo, Nchafatso G., Liu, Keibun, Ainola, Carmen, Sato, Noriko, Abbate, Gabriella, Wilson, Emily S., Bouquet, Mahé, Hyslop, Kieran, Passmore, Margaret R., Ijuin, Shinichi, Ro, Sun Kyun, Fior, Gabriele, Gandini, Lucia, Lundon, Brooke, Platts, David G., Suen, Jacky Y., Bassi, Gianluigi Li and Fraser, John F. (2024). A novel echocardiographic parameter considering left ventricular afterload during V‐A ECMO support. European Journal of Clinical Investigation, 54 (10) e14263, e14263. doi: 10.1111/eci.14263
Chan, Chris H. H., Passmore, Margaret R., Tronstad, Oystein, Seale, Helen, Bouquet, Mahe, White, Nicole, Teruya, Jun, Hogan, Airlie, Platts, David, Chan, Wandy, Dashwood, Alexander M., McGiffin, David C., Maiorana, Andrew J., Hayward, Christopher S., Simmonds, Michael J., Tansley, Geoff D., Suen, Jacky Y., Fraser, John F., Meyns, Bart, Fresiello, Libera and Jacobs, Steven (2024). The Impact of Acute Exercise on Hemostasis and Angiogenesis Mediators in Patients With Continuous-Flow Left Ventricular Assist Devices: A Prospective Observational Pilot Study. ASAIO Journal. doi: 10.1097/mat.0000000000002246
Heinsar, Silver, Sato, Kei, Obonyo, Nchafatso, Farah, Samia M, Bouquet, Mahe, Passmore, Margaret R, Liu, Keibun, Ijunin, Shinichi, Ainola, Carmen, Li Bassi, Gianluigi, Suen, Jacky Y and Fraser, John F. (2024). Improved microcirculation with pulsatile veno-arterial ECMO: an ovine model of cardiogenic shock. American Journal of Respiratory and Critical Care Medicine, 209 (11), 1396-1399. doi: 10.1164/rccm.202402-0419le
Sato, Kei, Wildi, Karin, Chan, Jonathan, Palmieri, Chiara, Obonyo, Nchafatso G., Heinsar, Silver, Liu, Keibun, Livingstone, Samantha, Sato, Noriko, Ainola, Carmen, Abbate, Gabriella, Bouquet, Mahé, Wilson, Emily, Passmore, Margaret, Hyslop, Kieran, Platts, David G., Suen, Jacky, Bassi, Gianluigi Li and Fraser, John F. (2024). A novel speckle‐tracking echocardiography parameter assessing left ventricular afterload. European Journal of Clinical Investigation, 54 (2) e14106, 1-12. doi: 10.1111/eci.14106
Wildi, Karin, Colombo, Sebastiano Maria, McGuire, Daniel, Ainola, Carmen, Heinsar, Silver, Sato, Noriko, Sato, Kei, Liu, Keibun, Bouquet, Mahé, Wilson, Emily, Passmore, Margaret, Hyslop, Kieran, Livingstone, Samantha, Di Feliciantonio, Marianna, Strugnell, Wendy, Palmieri, Chiara, Suen, Jacky, Li Bassi, Gianluigi and Fraser, John (2024). An appraisal of lung computer tomography in very early anti-inflammatory treatment of two different ovine ARDS phenotypes. Scientific Reports, 14 (1) 2162, 1-11. doi: 10.1038/s41598-024-52698-w
Malfertheiner, Maximilian V., Ashlen, Garrett, Margaret, Passmore, Haymet, Andrew B., Richard, Webb I., von Bahr, Viktor, Millar, Jonathan E., Schneider, Bailey A., Obonyo, Nchafatso G., Debra, Black, Mahe, Bouquet, Nicole, Bartnikowski, Suen, Jacky Y. and Fraser, John F. (2023). The effects of nitric oxide on coagulation and inflammation in ex‐vivo models of extracorporeal membrane oxygenation and cardiopulmonary bypass. Artificial Organs, 47 (10), 1581-1591. doi: 10.1111/aor.14608
Wildi, Karin, Livingstone, Samantha, Ainola, Carmen, Colombo, Sebastiano Maria, Heinsar, Silver, Sato, Noriko, Sato, Kei, Bouquet, Mahé, Wilson, Emily, Abbate, Gabriella, Passmore, Margaret, Hyslop, Kieran, Liu, Keibun, Wang, Xiaomeng, Palmieri, Chiara, See Hoe, Louise E., Jung, Jae-Seung, Ki, Katrina, Mueller, Christian, Laffey, John, Pelosi, Paolo, Li Bassi, Gianluigi, Suen, Jacky and Fraser, John (2023). Application of anti-inflammatory treatment in two different ovine Acute Respiratory Distress Syndrome injury models: a preclinical randomized intervention study. Scientific Reports, 13 (1) 17986, 1-15. doi: 10.1038/s41598-023-45081-8
See Hoe, Louise E., Bassi, Gianluigi Li, Wildi, Karin, Passmore, Margaret R., Bouquet, Mahe, Sato, Kei, Heinsar, Silver, Ainola, Carmen, Bartnikowski, Nicole, Wilson, Emily S., Hyslop, Kieran, Skeggs, Kris, Obonyo, Nchafatso G., Shuker, Tristan, Bradbury, Lucy, Palmieri, Chiara, Pedersen, Sanne-Engkilde, McDonald, Charles, Colombo, Sebastiano M., Wells, Matthew A., Reid, Janice D., O'Neill, Hollier, Livingstone, Samantha, Abbate, Gabriella, Haymet, Andrew, Jung, Jae-Seung, Sato, Noriko, James, Lynnette, He, Ting ... Fraser, John F. (2023). Donor heart ischemic time can be extended to 8 hours using hypothermic machine perfusion in sheep. The Journal of Heart and Lung Transplantation, 42 (8), 1015-1029. doi: 10.1016/j.healun.2023.03.020
Rozencwajg, Sacha, Heinsar, Silver, Wildi, Karin, Jung, Jae‐Seung, Colombo, Sebastiano Maria, Palmieri, Chiara, Sato, Kei, Ainola, Carmen, Wang, Xiaomeng, Abbate, Gabriella, Sato, Noriko, Dyer, Wayne B., Livingstone, Samantha, Helms, Leticia, Bartnikowski, Nicole, Bouquet, Mahe, Passmore, Margaret R., Hyslop, Kieran, Vidal, Bruno, Reid, Janice D., McGuire, Daniel, Wilson, Emily S., Rätsep, Indrek, Lorusso, Roberto, Schmidt, Matthieu, Suen, Jacky Y., Bassi, Gianluigi Li and Fraser, John F. (2023). Effect of flow change on brain injury during an experimental model of differential hypoxaemia in cardiogenic shock supported by extracorporeal membrane oxygenation. Scientific Reports, 13 (1) 4002, 1-11. doi: 10.1038/s41598-023-30226-6
Sato, Kei, Heinsar, Silver, Wildi, Karin Susanne, Obonyo, Nchafatso, LIU, KEIBUN, Farah, Samia, Ainola, Carmen, Sato, Noriko, Fior, Gabriele, Ro, Sun Kyun, Gandini, Lucia, Ijuin, Shinichi, Bouquet, Mahe, Wilson, Emily, Passmore, Margaret, Hyslop, Kieran, Chan, Jonathan H., Platts, David, Suen, Jacky, Bassi, Gianluigi Li and Fraser, John (2023). A novel speckle-tracking echocardiographic parameter considering left ventricular loading condition in cardiogenic shock during VA ECMO. Journal of the American College of Cardiology, 81 (8) 1396, 1-1. doi: 10.1016/s0735-1097(23)01840-5
Doyle, Barry J., Kelsey, Lachlan J., Shelverton, Caroline, Abbate, Gabriella, Ainola, Carmen, Sato, Noriko, Livingstone, Samantha, Bouquet, Mahe, Passmore, Margaret R, Wilson, Emily S., Colombo, Sebastiano, Sato, Kei, Liu, Keibun, Heinsar, Silver, Wildi, Karin, Carr, Peter J., Suen, Jacky, Fraser, John, Li Bassi, Gianluigi and Keogh, Samantha (2022). Design, development and preliminary assessment in a porcine model of a novel peripheral intravenous catheter aimed at reducing early failure rates. The Journal of Vascular Access, 25 (3), 11297298221127760-799. doi: 10.1177/11297298221127760
Wildi, Karin, Bouquet, Mahe, Ainola, Carmen, Livingstone, Samantha, Colombo, Sebastiano Maria, Heinsar, Silver, Sato, Noriko, Sato, Kei, Wilson, Emily, Abbate, Gabriella, Passmore, Margaret R., Hyslop, Kieran, Liu, Keibun, Li Bassi, Gianluigi, Suen, Jacky Y. and Fraser, John F. (2022). Differential protein expression among two different ovine ARDS phenotypes—A preclinical randomized study. Metabolites, 12 (7) 655, 1-17. doi: 10.3390/metabo12070655
Wildi, Karin, Hyslop, Kieran, Millar, Jonathan, Livingstone, Samantha, Passmore, Margaret R., Bouquet, Mahé, Wilson, Emily, LiBassi, Gianluigi, Fraser, John F. and Suen, Jacky Y. (2022). Validation of messenger ribonucleic acid markers differentiating among human acute respiratory distress syndrome subgroups in an ovine model of acute respiratory distress syndrome phenotypes. Frontiers in Medicine, 9 961336, 1-7. doi: 10.3389/fmed.2022.961336
See Hoe, Louise E., Bouquet, Mahe, Hyslop, Kieran, Passmore, Margaret R., Wells, Matthew A., Sato, Kei, Wilson, Emily, Wildi, Karin, Skeggs, Kris, Palmeri, Chiara, Reid, Janice, O'Neill, Hollier, Bartnikowski, Nicole, Jung, Jae-Seung, Ainola, Carmen, Abbate, Gabriella, Colombo, Sebastiano M., Obonyo, Nchafatso G., McDonald, Charles, Shuker, Tristan, Heinsar, Silver, Haymet, Andrew, Pedersen, Sanne, Molenaar, Peter, Li Bassi, Gianluigi, Suen, Jacky Y., McGiffin, David C. and Fraser, John F. (2022). Hypothermic ex vivo perfusion of donor hearts can safely preserve post-transplant cardiac function in sheep for 8 hours. The FASEB Journal, 36 (S1). doi: 10.1096/fasebj.2022.36.S1.R3270
See Hoe, Louise E., Wildi, Karin, Obonyo, Nchafatso G., Bartnikowski, Nicole, McDonald, Charles, Sato, Kei, Heinsar, Silver, Engkilde-Pedersen, Sanne, Diab, Sara, Passmore, Margaret R., Wells, Matthew A., Boon, Ai-Ching, Esguerra, Arlanna, Platts, David G., James, Lynnette, Bouquet, Mahe, Hyslop, Kieran, Shuker, Tristan, Ainola, Carmen, Colombo, Sebastiano M., Wilson, Emily S., Millar, Jonathan E., Malfertheiner, Maximillian V., Reid, Janice D., O’Neill, Hollier, Livingstone, Samantha, Abbate, Gabriella, Sato, Noriko, He, Ting ... Fraser, John F. (2021). A clinically relevant sheep model of orthotopic heart transplantation 24 h after donor brainstem death. Intensive Care Medicine Experimental, 9 (1) 60, 1-24. doi: 10.1186/s40635-021-00425-4
Walweel, K., Boon, A. C., See Hoe, L. E., Obonyo, N. G., Pedersen, S. E., Diab, S. D., Passmore, M. R., Hyslop, K., Colombo, S. M., Bartnikowski, N. J., Bouquet, M., Wells, M. A., Black, D. M., Pimenta, L. P., Stevenson, A. K., Bisht, K., Skeggs, K., Marshall, L., Prabhu, A., James, L. N., Platts, D. G., Macdonald, P. S., McGiffin, D. C., Suen, J. Y. and Fraser, J. F. (2021). Brain stem death induces pro-inflammatory cytokine production and cardiac dysfunction in sheep model. Biomedical Journal, 45 (5), 776-787. doi: 10.1016/j.bj.2021.10.007
Heinsar, Silver, Jung, Jae-Seung, Colombo, Sebastiano Maria, Rozencwajg, Sacha, Wildi, Karin, Sato, Kei, Ainola, Carmen, Wang, Xiaomeng, Abbate, Gabriella, Sato, Noriko, Dyer, Wayne Bruce, Livingstone, Samantha Annie, Pimenta, Leticia Pretti, Bartnikowski, Nicole, Bouquet, Mahe Jeannine Patricia, Passmore, Margaret, Vidal, Bruno, Palmieri, Chiara, Reid, Janice D., Haqqani, Haris M., McGuire, Daniel, Wilson, Emily Susan, Rätsep, Indrek, Lorusso, Roberto, Suen, Jacky Y., Li Bassi, Gianluigi and Fraser, John F. (2021). An innovative ovine model of severe cardiopulmonary failure supported by veno-arterial extracorporeal membrane oxygenation. Scientific Reports, 11 (1) 20458, 1-11. doi: 10.1038/s41598-021-00087-y
Millar, Jonathan E., Wildi, Karin, Bartnikowski, Nicole, Bouquet, Mahe, Hyslop, Kieran, Passmore, Margaret R., Ki, Katrina K., See Hoe, Louise E., Obonyo, Nchafatso G., Neyton, Lucile, Pedersen, Sanne, Rozencwajg, Sacha, Baillie, J. Kenneth, Li Bassi, Gianluigi, Suen, Jacky Y., McAuley, Daniel F. and Fraser, John F. (2021). Characterizing preclinical sub-phenotypic models of acute respiratory distress syndrome: an experimental ovine study. Physiological Reports, 9 (19) e15048, e15048. doi: 10.14814/phy2.15048
Livingstone, Samantha A., Wildi, Karin S., Dalton, Heidi J., Usman, Asad, Ki, Katrina K., Passmore, Margaret R., Li Bassi, Gianluigi, Suen, Jacky Y. and Fraser, John F. (2021). Coagulation dysfunction in acute respiratory distress syndrome and its potential impact in inflammatory subphenotypes. Frontiers in Medicine, 8 723217, 723217. doi: 10.3389/fmed.2021.723217
Wells, Matthew A., See Hoe, Louise E., Molenaar, Peter, Pedersen, Sanne, Obonyo, Nchafatso G., McDonald, Charles I., Mo, Weilan, Bouquet, Mahè, Hyslop, Kieran, Passmore, Margaret R., Bartnikowski, Nicole, Suen, Jacky Y., Peart, Jason N., McGiffin, David C., Fraser, John F. and on behalf of the Dead Heart Project (2021). Compromised right ventricular contractility in an ovine model of heart transplantation following 24 h donor brain stem death. Pharmacological Research, 169 105631, 1-12. doi: 10.1016/j.phrs.2021.105631
Ki, Katrina K., Millar, Jonathan E., Langguth, Daman, Passmore, Margaret R., McDonald, Charles I., Shekar, Kiran, Shankar-Hari, Manu, Cho, Hwa Jin, Suen, Jacky Y. and Fraser, John F. (2021). Current understanding of leukocyte phenotypic and functional modulation during extracorporeal membrane oxygenation: a narrative review. Frontiers in Immunology, 11 600684, 600684. doi: 10.3389/fimmu.2020.600684
Passmore, Margaret R., Ki, Katrina K., Chan, Chris H. H., Lee, Talvin, Bouquet, Mahé, Wood, Emily S., Raman, Sainath, Rozencwajg, Sacha, Burrell, Aidan J. C., McDonald, Charles I., Langguth, Daman, Shekar, Kiran, Malfertheiner, Maximilian V., Fraser, John F. and Suen, Jacky Y. (2020). The effect of hyperoxia on inflammation and platelet responses in an ex vivo extracorporeal membrane oxygenation circuit. Artificial Organs, 44 (12) aor.13771, 1276-1285. doi: 10.1111/aor.13771
Walweel, K., Skeggs, K., Boon, A. C., See Hoe, L. E., Bouquet, M., Obonyo, N. G., Pedersen, S. E., Diab, S. D., Passmore, M. R., Hyslop, K., Wood, E. S., Reid, J., Colombo, S. M., Bartnikowski, N. J., Wells, M. A., Black, D., Pimenta, L. P., Stevenson, A. K., Bisht, K., Marshall, L., Prabhu, D. A., James, L., Platts, D. G., MacDonald, P. S., McGiffin, D. C., Suen, J. Y. and Fraser, J. F. (2020). Endothelin receptor antagonist improves donor lung function in an ex vivo perfusion system. Journal of Biomedical Science, 27 (1) 96, 96. doi: 10.1186/s12929-020-00690-7
Bouquet, Mahé, Passmore, Margaret R., See Hoe, Louise E., Tung, John-Paul, Simonova, Gabriela, Boon, Ai-Ching and Fraser, John F. (2020). Development and validation of ELISAs for the quantitation of interleukin (IL)-1β, IL-6, IL-8 and IL-10 in ovine plasma. Journal of Immunological Methods, 486 112835, 112835. doi: 10.1016/j.jim.2020.112835
Millar, Jonathan E., Bartnikowski, Nicole, Passmore, Margaret R., Obonyo, Nchafatso G, Malfertheiner, Maximillian V., von Bahr, Viktor, Redd, Meredith A., See Hoe, Louise, Ki, Katrina K., Pedersen, Sanne, Boyle, Andrew J., Baillie, J Kenneth, Shekar, Kiran, Palpant, Nathan, Suen, Jacky Y., Matthay, Michael A., McAuley, Daniel F., Fraser, John F. and Combining Extracorporeal Life Support and Cell Therapy in Critical Illness (CELTIC) investigators (2020). Combined mesenchymal stromal cell therapy and ECMO in ARDS: a controlled experimental study in sheep. American Journal of Respiratory and Critical Care Medicine, 202 (3) rccm.201911-2143OC, 383-392. doi: 10.1164/rccm.201911-2143oc
Ki, Katrina K., Passmore, Margaret R., Chan, Chris H. H., Malfertheiner, Maximilian V., Fanning, Jonathon P., Bouquet, Mahé, Millar, Jonathan E., Fraser, John F. and Suen, Jacky Y. (2019). Low flow rate alters haemostatic parameters in an ex-vivo extracorporeal membrane oxygenation circuit. Intensive Care Medicine Experimental, 7 (1) 51, 51. doi: 10.1186/s40635-019-0264-z
Passmore, Margaret R., Obonyo, Nchafatso G., Byrne, Liam, Boon, Ai-Ching, Diab, Sara D., Dunster, Kimble R., Fung, Yoke L., Spanevello, Michelle M., Fauzi, Mohd H., Pedersen, Sanne E., Simonova, Gabriela, Anstey, Chris M., Shekar, Kiran, Tung, John-Paul, Maitland, Kathryn and Fraser, John F. (2019). Fluid resuscitation with 0.9% saline alters haemostasis in an ovine model of endotoxemic shock. Thrombosis Research, 176, 39-45. doi: 10.1016/j.thromres.2019.02.015
von Bahr, Viktor, Millar, Jonathan E., Malfertheiner, Maximillian V., Ki, Katrina K., Passmore, Margaret R., Bartnikowski, Nicole, Redd, Meredith A., Cavaye, Michael, Suen, Jacky Y., McAuley, Danny F. and Fraser, John F. (2019). Mesenchymal stem cells may ameliorate inflammation in an ex vivo model of extracorporeal membrane oxygenation. Perfusion, 34 (1_suppl), 15-21. doi: 10.1177/0267659119830857
Ki, Katrina K., Passmore, Margaret R., Chan, Chris Hoi Houng, Malfertheiner, Maximillian V, Bouquet, Mahe, Cho, Hwa Jin, Suen, Jacky Y. and Fraser, John F. (2019). Effect of ex vivo extracorporeal membrane oxygenation flow dynamics on immune response. Perfusion, 34 (1_suppl), 5-14. doi: 10.1177/0267659119830012
Fanning, Jonathon P., Hoe, Louise E. See, Passmore, Margaret R., Barnett, Adrian G., Obonyo, Nchafatso G., Millar, Jonathan E., Wesley, Allan J., Suen, Jacky Y. and Fraser, John F. (2019). Neuron specific enolase and matrix metalloproteinase 9 signal perioperative silent brain infarction during or after transcatheter aortic valve implantation. The American Journal of Cardiology, 123 (3), 434-439. doi: 10.1016/j.amjcard.2018.10.022
Obonyo, Nchafatso G., Byrne, Liam, Tung, John-Paul, Simonova, Gabriela, Diab, Sara D., Dunster, Kimble R., Passmore, Margaret R., Boon, Ai-Ching, See Hoe, Louise, Engkilde-Pedersen, Sanne, Esguerra-Lallen, Arlanna, Fauzi, Mohd H., Pimenta, Leticia P., Millar, Jonathan E., Fanning, Jonathon P., Van Haren, Frank, Anstey, Chris M., Cullen, Louise, Suen, Jacky, Shekar, Kiran, Maitland, Kathryn and Fraser, John F. (2019). Pre-clinical study protocol: Blood transfusion in endotoxaemic shock. MethodsX, 6, 1124-1132. doi: 10.1016/j.mex.2019.05.005
Passmore, Margaret R., Byrne, Liam, Obonyo, Nchafatso G., See Hoe, Louise E., Boon, Ai-Ching, Diab, Sara D., Dunster, Kimble R., Bisht, Kavita, Tung, John-Paul, Fauzi, Mohd H., Narula, Monica, Pedersen, Sanne E., Esguerra-Lallen, Arlanna, Simonova, Gabriela, Sultana, Annette, Anstey, Chris M., Shekar, Kiran, Maitland, Kathryn, Suen, Jacky Y. and Fraser, John F. (2018). Inflammation and lung injury in an ovine model of fluid resuscitated endotoxemic shock. Respiratory Research, 19 (1) 231, 231. doi: 10.1186/s12931-018-0935-4
Byrne, Liam, Obonyo, Nchafatso G., Diab, Sara D., Dunster, Kimble R., Passmore, Margaret R., Boon, Ai-Ching, See Hoe, Louise, Pedersen, Sanne, Hashairi Fauzi, Mohd, Pretti Pimenta, Leticia, Van Haren, Frank, Anstey, Christopher M., Cullen, Louise, Tung, John-Paul, Shekar, Kiran, Maitland, Kathryn and Fraser, John F. (2018). Unintended consequences: fluid resuscitation worsens shock in an ovine model of endotoxemia. American Journal of Respiratory and Critical Care Medicine, 198 (8), 1043-1054. doi: 10.1164/rccm.201801-0064OC
Fanning, Jonathon P., See Hoe, Louise E., Passmore, Margaret R., Barnett, Adrian G., Rolfe, Barbara E., Millar, Jonathan E., Wesley, Allan J., Suen, Jacky and Fraser, John F. (2018). Differential immunological profiles herald magnetic resonance imaging-defined perioperative cerebral infarction. Therapeutic Advances in Neurological Disorders, 11, 1756286418759493. doi: 10.1177/1756286418759493
Byrne, Liam, Obonyo, Nchafatso G., Diab, Sara, Dunster, Kimble, Passmore, Margaret, Boon, Ai Ching, Hoe, Louise See, Hay, Karen, Van Haren, Frank, Tung, John-Paul, Cullen, Louise, Shekar, Kiran, Maitland, Kathryn and Fraser, John F. (2018). An ovine model of hyperdynamic endotoxemia and vital organ metabolism. Shock, 49 (1), 99-107. doi: 10.1097/SHK.0000000000000904
Passmore, Margaret R., Fung, Yoke L., Simonova, Gabriela, Foley, Samuel R., Diab, Sara D., Dunster, Kimble R., Spanevello, Michelle M., McDonald, Charles I., Tung, John-Paul, Pecheniuk, Natalie M., Hay, Karen, Shekar, Kiran and Fraser, John F. (2017). Evidence of altered haemostasis in an ovine model of venovenous extracorporeal membrane oxygenation support. Critical Care, 21 (1) 191, 1-9. doi: 10.1186/s13054-017-1788-9
Passmore, Margaret R., Fung, Yoke L., Simonova, Gabriela, Foley, Samuel R., Dunster, Kimble R., Diab, Sara D., Tung, John-Paul, Minchinton, Robyn M., McDonald, Charles I., Anstey, Chris M., Shekar, Kiran and Fraser, John F. (2016). Inflammation and lung injury in an ovine model of extracorporeal membrane oxygenation support. AJP - Lung Cellular and Molecular Physiology, 311 (6), L1202-L1212. doi: 10.1152/ajplung.00296.2016
McDonald, Charles I, Fung, Yoke Lin, Shekar, Kiran, Diab, Sara D, Dunster, Kimble R, Passmore, Margaret R, Foley, Samuel R, Simonova, Gabriela, Platts, David and Fraser, John F (2015). The impact of acute lung injury, ECMO and transfusion on oxidative stress and plasma selenium levels in an ovine model. Journal of Trace Elements in Medicine and Biology, 30, 4-10. doi: 10.1016/j.jtemb.2015.01.004
Passmore, Margaret, Nataatmadja, Maria, Fung, Yoke L., Pearse, Bronwyn, Gabriel, Sarah, Tesar, Peter and Fraser, John F. (2015). Osteopontin alters endothelial and valvular interstitial cell behaviour in calcific aortic valve stenosis through HMGB1 regulation. European Journal of Cardio-thoracic Surgery, 48 (3), e20-e29. doi: 10.1093/ejcts/ezv244
Nataatmadja, Maria, Passmore, Margaret, Russell, Fraser D., Prabowo, Sulistiana, Corley, Amanda and Fraser, John F. (2014). Angiotensin receptors as sensitive markers of acute bronchiole injury after lung transplantation. Lung, 192 (4), 563-569. doi: 10.1007/s00408-014-9588-3
Passmore, Margaret R., Nataatmadja, Maria and Fraser, John F. (2012). Assessment of control tissue for gene and protein expression studies: A Comparison of three alternative lung sources. Scientific World Journal, 2012 523840, 523840.1-523840.8. doi: 10.1100/2012/523840
Ogilvie, Varrie, Passmore, Margaret, Hyndman, Laura, Jones, Lisa, Stevenson, Barbara, Wilson, Abigail, Davidson, Heather, Kitchen, Robert R., Gray, Robert D., Shah, Pallav, Alton, Eric W., Davies, Jane C., Porteous, David J. and Boyd, A. Christopher (2011). Differential global gene expression in cystic fibrosis nasal and bronchial epithelium. Genomics, 98 (5), 327-336. doi: 10.1016/j.ygeno.2011.06.008
Passmore, Margaret, Nataatmadja, Maria I. and Fraser, John (2009). Selection of reference genes for normalisation of real-time RT-PCR in brain-stem death injury in Ovis aries. BMC Molecular Biology, 10 (72) 72, x-x. doi: 10.1186/1471-2199-10-72
Brown, Lindsay, Passmore, Margaret, Duce, Brett and Sernia, Conrad (1997). Angiotensin receptors in cardiac and renal hypertrophy in rats. Journal of Molecular and Cellular Cardiology, 29 (11), 2925-2929. doi: 10.1006/jmcc.1997.0527
Conference Papers
Sato, K., Heinsar, S., Obonyo, N., Wildi, K., Liu, K., Farah, S., Ainola, C., Sato, N., Ijuin, S., Ro, S. Kyun, Fior, G., Gandini, L., Bouquet, M., Wilson, E., Passmore, M., Hyslop, K., Chan, J., Platts, D., Scalia, G., Suen, J., Bassi, G. Li and Fraser, J. (2023). A novel speckle-tracking echocardiographic parameter assessing left ventricular loading during VA ECMO in a pre-clinical model of cardiogenic shock. 71st Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, Adelaide, SA Australia, 3-6 August 2023. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2023.06.562
Palmieri, C., See Hoe, L., Dyer, W., Heinsar, S., Rozencwaig, S., Tung, J.P., Bartnikowski, N., Passmore, M., Bouquet, M., Hislop, K., Wilson, E., Li Bassi, g., Mcgiffin, D., Suen, J. and Fraser, J. (2023). Proposal of a reliable scoring system for the histological assessment of multiorgan injury in large animal models of ischaemia and shock. 2022 Annual Congress of the European Society of Veterinary Pathology and European College of Veterinary Pathologists, Athens, Greece, 7 - 10 September 2022. London, United Kingdom: Elsevier. doi: 10.1016/j.jcpa.2023.03.059
Sato, Kei, Heinsar, Silver, Wildi, Karin Susanne, Obonyo, Nchafatso, Liu, Keibun, Farah, Samia, Ainola, Carmen, Sato, Noriko, Fior, Gabriele, Ro, Sun Kyun, Gandini, Lucia, Ijuin, Shinichi, Bouquet, Mahe, Wilson, Emily, Passmore, Margaret, Hyslop, Kieran, Chan, Jonathan H., Platts, David, Suen, Jacky, Li Bassi, Gianluigi and Fraser, John (2023). A novel speckle-tracking echocardiographic parameter considering left ventricular loading condition in cardiogenic shock during VA ECMO. 72nd Annual Scientific Session (ACC), New Orleans, LA, United States, 4-6 March 2023. San Diego, CA, United States: Elsevier.
Wildi, K., Livingstone, S., Ainola, C., Colombo, S. M., Heinsar, S., Sato, N., Sato, K., Bouqet, M., Wilson, E., Abbate, G., Passmore, M., Hyslop, K., Liu, K., Palmieri, C., Ki, K., LiBassi, G., Suen, J. and Fraser, J. (2022). Early clinical improvement in ARDS results from selecting the right subphenotype for anti-inflammatory treatment - a preclinical randomized blinded ovine study. American Thoracic Society 2022 International Conference, San Francisco, United States, 13-18 May 2022. New York, United States: American Thoracic Society. doi: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a3430
See Hoe, L., Bouquet, M., Hyslop, K., Passmore, M., Wells, M., Sato, K., Wilson, E., Wildi, K., Skeggs, K., Palmeri, C., Reid, J., O'Neill, H., Bartnikowski, N., Jung, J., Ainola, C., Abbate, G., Colombo, S., Obonyo, N., McDonald, C., Shuker, T., Heinsar, S., Haymet, A., Engkilde-Pedersen, S., Peart, J., Molenaar, P., Li Bassi, G., Suen, J., McGiffin, D. and Fraser, J. (2022). Post-transplant cardiac contractility and mitochondrial function is preserved following 8 hours hypothermic ex vivo perfusion in sheep. 70th Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, Gold Coast, QLD, Australia, 11-14 August 2022. Chatswood, NSW, Australia: Elsevier. doi: 10.1016/j.hlc.2022.06.547
Wildi, K., Hyslop, K., Livingstone, S., Ainola, C., Heinsar, S., Sato, K., Sato, N., Abbate, G., Bouquet, M., Passmore, M., Wilson, E., LiBassi, G., Suen, J. and Fraser, J. (2021). Validation of an ovine model of biological ARDS subphenotypes by reproducing mRNA expression profiles. American Thoracic Society 2021 International Conference, Virtual, 14-19 May 2021. New York, United States: American Thoracic Society. doi: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2698
Hoe, L. E. See, Wildi, K., Skeggs, K., Bouquet, M., Sato, K., Jung, J., Ainola, C., Hyslop, K., Heinsar, S., Abbate, G., Colombo, S. M., Passmore, M., Wood, E. S., Wells, M., Bartnikowski, N., O'Neill, H., Reid, J., Shuker, T., Haymet, A., Livingstone, S., Sato, N., Obonyo, N., James, L., He, T., McDonald, C., Mullins, D., Engkilde-Pedersen, S., Diab, S., Millar, J. E. ... Fraser, J. F. (2021). Donor heart preservation by hypothermic ex vivo perfusion - improved recipient survival and successful prolongation of ischemic time. ISHLT 41st Annual Meeting, Virtual, 24-28 April 2021. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.healun.2021.01.1864
Hoe, L.E. See, Wildi, K., Skeggs, K., Bouquet, M., Sato, K., Jung, J., Ainola, C., Hyslop, K., Heinsar, S., Abbate, G., Colombo, S.M., Passmore, M., Wood, E.S., Wells, M., Bartnikowski, N., O'Neill, H., Reid, J., Shuker, T., Haymet, A., Livingstone, S., Sato, N., Obonyo, N., James, L., He, T., McDonald, C., Mullins, D., Engkilde-Pedersen, S., Diab, S., Millar, J.E. ... Fraser, J.F. (2021). Donor heart preservation by hypothermic ex vivo perfusion - improved recipient survival and successful prolongation of ischemic time. ISHLT 41th Annual Meeting, Online, 24-28 April 2021. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.healun.2021.01.1864
Sato, K., See Hoe, L., Obonyo, N., Wildi, K., Colombo, S., Bouquet, M., Passmore, M., Bartnikowski, N., Wells, M., Skeggs, K., McDonald, C., Hyslop, K., Wood, E., Heinser, S., Ainola, C., Jung, J., James, L., Abbate, G., Haymet, A., Engkilde-Pedersen, S., Reid, J., O'Neill, H., Shuker, T., He, P., Sato, N., Diab, S., Mullins, D., Livingstone, S., Wang, X. ... Fraser, J. (2020). Hypothermic ex vivo perfusion preserves post-transplant donor cardiac function. 8th Cardiac Society of Australia and New Zealand Annual Scientific Meeting, the International Society for Heart Research Australasian Section Annual Scientific Meeting and the 14th Annual Australia and New Zealand Endovascular Therapies Meeting, Virtual, 11-13 December 2020. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2020.09.128
Hoe, L. E. See, Wells, M. A., Bouquet, M., Hyslop, K., Passmore, M. R., Bartnikowski, N., Obonyo, N. G., Reid, J., O'Neill, H., Shuker, T., McDonald, C., Engkilde-Pedersen, S., Wildi, K., Ainola, C., Skeggs, K., Jung, J., Colombo, S., Sato, K., James, L., He, P., Wood, E. S., Heinser, S., Wang, X., Abbate, G., Livingstone, S., Haymet, A., Walweel, K., Mullins, D., Marasco, S. ... Fraser, J. F. (2020). Metabolic and mitochondrial alterations following brain death and heart transplantation. 40th Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation (ISHLT), Montreal, Canada, 22-25 April 2020. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.healun.2020.01.419
See Hoe, L., McGiffin, D., Wildi, K., Obonyo, N., Bouquet, M., Wells, M., Skeggs, K., McDonald, C., Engkilde-Pedersen, S., Bartnikowski, N., Colombo, S., Ainola, C., Passmore, M., Hyslop, K., Wood, E., Shuker, T., Sato, K., Jung, J., Heinser, S., James, L., Reid, J., O'Neill, H., Livingstone, S., Abbate, G., He, P., Sato, N., Boon, C., Black, D., Haymet, A. ... Fraser, J. (2020). Hypothermic ex vivo perfusion of brain dead donor hearts improves survival, systemic inflammation and cardiac function following heart transplantation. 8th Cardiac Society of Australia and New Zealand Annual Scientific Meeting, the International Society for Heart Research Australasian Section Annual Scientific Meeting and the 14th Annual Australia and New Zealand Endovascular Therapies Meeting, Online, 11-13 December 2020. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2020.09.127
Li Bassi, G. , Colombo, S., Heinsar, S., Wildi, K., Ainola, C., Jung, J., Abbate, G., Hoe, L. See, Sato, K., Wang, X., Skeggs, K., Livingstone, S., Boquet, M., Passmore, M., Sato, N., Reid, J., James, L., Wilson, E., McGiffin, D., Suen, J. and Fraser, J. (2020). The Effects of Different Ventilatory Strategies on Pulmonary Mechanics and Gas Exchange During Heart Transplant: An Experimental Study. International Conference of the American Thoracic Society, Online, 2020. New York, NY United States: American Thoracic Society.
Wells, Matthew, Molenaar, Peter, Hoe, Louise See, Obonyo, Nchafatso, James, Lynette, Bouquet, Mahe, Bartnikowski, Nicole, Passmore, Margaret, Boone, Connie, Wilde, Karin, Weilan, Mo, Hyslop, Kieran, McDonald, Charles, Pedersen, Sanne, Suen, Jacky, Peart, Jason, McGiffin, David and Fraser, John (2020). (-)-Noradrenaline sensitivity, contractility and mitochondrial function in an ovine model of brain stem death and transplantation. 2019 ISHR World Congress, Beijing, China, 3-6 June 2019. London, United Kingdom: Academic Press. doi: 10.1016/j.yjmcc.2019.11.114
Hoe, L. See, Shuker, T., Bartnikowski, N., Passmore, M., Bouquet, M., Obonyo, N., Engkilde-Pedersen, S., McDonald, C., Wells, M., Boon, A., Hyslop, K., James, L., Wildi, K., Cullen, L., Bassi, G. Li, Suen, J., McGiffin, D. and Fraser, J. (2019). Characterisation of cardiac neurohormonal and inflammatory changes induced by brain death in a novel ovine heart transplant model. 67th Cardiac Society of Australia and New Zealand Annual Scientific Meeting, the International Society for Heart Research Australasian Section Annual Scientific Meeting and the 13th Annual Australia and New Zealand Endovascular Therapies Meeting, Adelaide, Australia, 8-11 August 2019. chatswood, NSW, Australia: Elsevier. doi: 10.1016/j.hlc.2019.06.074
Fanning, Jonathon P., Obonyo, Nchafatso G., Tung, John-Paul, Byrne, Liam, Simonova, Gabriela, Diab, Sara, Dunster, Kimble, Passmore, Margaret, Boon, Ai-Ching, See Hoe, Louise, Engkilde-Pedersen, Sanne, Esguerra-Lallen, Arlanna, Hashairi Fauzi, Mohd, Pretti Pimenta, Leticia, Millar, Jonathan, Anstey, Christopher, van Haren, Frank, Cullen, Louise, Suen, Jacky, Shekar, Kiran, Maitland, Kathryn and Fraser, John (2018). Packed Red Cell Age Associated With Adverse Cardiovascular Changes in an Ovine Model of Septic Shock Resuscitation. American Heart Association's 2018 Scientific Sessions, Chicago, IL United States, 10-12 November 2018. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1161/circ.138.suppl_1.17116
Obonyo, N., Byrne, L., Shiino, K., Diab, S., Dunster, K., Passmore, M., Boon, A.C., See Hoe, L., Pedersen, S., Fauzi, M., Pimenta, L., Van Haren, F., Shekar, K., Anstey, C., Tung, J.P., Cullen, L., Platts, D., Chan, J., Maitland, K. and Fraser, J. (2018). Fluid resuscitation with 0.9% saline impairs myocardial contractility in an ovine model of endotoxemic shock. 9th Congress of the World Federation of Pediatric Intensive & Critical Care Societies (WFPICCS 2018), Singapore, 9-13 June 2018. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.pcc.0000538016.15507.8c
See Hoe, L., Engkilde-Pedersen, S., Obonyo, N., Wells, M., Boon, C., Bartnikowski, N., Passmore, M., McDonald, C., Black, D., Molenaar, P., Diab, S., Suen, J., Marasco, S., McGiffin, D. and Fraser, J. (2018). Development of an ovine model of heart transplantation following 24-hour brain stem death. 66th Cardiac Society of Australia and New Zealand Annual Scientific Meeting, the International Society for Heart Research Australasian Section Annual Scientific Meeting and the 12th Annual Australia and New Zealand Endovascular Therapies Meeting, Brisbane, Australia, 2-5 August 2018. Chatswood, NSW, Australia: Elsevier . doi: 10.1016/j.hlc.2018.06.111
Tsui, Michelle, Obonyo, Nchafatso G., Boon, Ai Ching, Hoe, Louise See, Bartnikowski, Nicole J., Passmore, Margaret R., Pedersen, Sanne Engkilde S. P., Diab, Sara D., McGiffin, David C. and Fraser, John F. (2018). Pre-transplant microcirculatory profile in an ovine model of brain stem death. Owen Wangensteen Scientific Forum / Annual Clinical Congress of the American-College-of-Surgeons (ACS), Boston, MA, United States, 21-25 October 2018. New York, United States: Elsevier. doi: 10.1016/j.jamcollsurg.2018.08.608
Fanning, Jonathon P., Hoe, See Louise E., Passmore, Margaret R., Barnett, Adrian G., Obonyo, Nchafatso G., Millar, Jonathan E., Suen, Jacky Y. and Fraser, John F. (2018). Neuron specific enolase and matrix metaloproteinase 9 signal silent brain infarction associated with TAVI. Philadelphia, PA, United States: Lippincott Williams & Wilkins.
Fanning, Jonathon P., Obonyo, Nchafatso G., Tung, John-Paul, Byrne, Liam, Simonova, Gabriela, Diab, Sara, Dunster, Kimble, Passmore, Margaret, Boon, Ai-Ching, Hoe, See Louise, Engkilde-Pedersen, Sanne, Esguerra-Lallen, Arlanna, Fauzi, Hashairi Mohd, Pretti, Pimenta Leticia, Millar, Jonathan, Anstey, Christopher, van Haren, Frank, Cullen, Louise, Suen, Jacky, Shekar, Kiran, Maitland, Kathryn and Fraser, John (2018). Packed red cell age associated with adverse cardiovascular changes in an ovine model of septic shock resuscitation. -, -, 2018. Philadelphia, PA United States: Lippincott Williams & Wilkins.
Boon, A. C., Hoe, L. E. See, Pederson, S. E., Obonyo, N. G., Wells, M. A., Bartnikowski, N. J., Passmore, M. R., Marshall, L., James, L., Tung, J., Suen, J. Y., Macdonald, P. S., McGiffin, D. C. and Fraser, J. F. (2018). Inflammatory cytokine profiles in 24-hour brain stem death model. 38th Annual Meeting and Scientific Sessions of the International-Society-for-Heart-and-Lung-Transplantation (ISHLT), Nice, France, 11-14 April 2018. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.healun.2018.01.506
See Hoe, L., Obonyo, N., Byrne, L., Shiino, K., Diab, S., Dunster, K., Passmore, M., Boon, C., Engkilde-Pedersen, S., Esguerra, A., Fauzi, M., Pretti Pimenta, L., Simonova, G., Van Haren, F., Shekar, K., Anstey, C., Tung, J., Cullen, L., Platts, D., Chan, J., Maitland, K. and Fraser, J. (2018). Fluid resuscitation with 0.9% saline impairs myocardial contractility in an ovine model of endotoxaemic shock. 66th Cardiac Society of Australia and New Zealand Annual Scientific Meeting, the International Society for Heart Research Australasian Section Annual Scientific Meeting and the 12th Annual Australia and New Zealand Endovascular Therapies Meeting, Brisbane, Australia, 2-5 August 2018. Chatswood, NSW, Australia: Elsevier. doi: 10.1016/j.hlc.2018.06.129
Roche, Elise, Passmore, Margaret, Simonova, Gabriela, Diab, Sara, Dunster, Kimble, Bierman, Wesley, Fraser, John and Tung, John-Paul (2016). A Histologic Approach to Qualify Lung Tissue Damage in a Sheep Model of Transfusion-Related Lung Injury: Role of Red Blood Cell Storage Duration and Heat Treatment. 2016 American Society of Clincial Pathology (ASCP) Annual Meeting, Las Vegas, NV United States, 14 -16 September 2016. Cary, NC United States: Oxford University Press.
Fung, Y.L., Diab, S., Dunster, K., Foley, S.R., McDonald, C.I., Passmore, M., Platts, D., Simonova, G., Shekar, K., Stewart, D. and Fraser, J.F. (2012). Extracorporeal lessons from sheep. 32nd International Congress of the International Society of Blood Transfusion in joint cooperation with the 10th Congress of AMMTAC, Cancun, Mexico, 7-12 July 2012. Oxford, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/j.1423-0410.2012.01615_1.x
Nataatmadja, M., Passmore, M., Russell, F., Corley, A., Hopkins, P., Chambers, D., Kermeen, F. and Fraser, J. F. (2010). Systemic and local upregulation of the angiotensin II system is associated with lung transplant injury. American Thoracic Society 2010 International Conference, New Orleans, LA United States, 14-19 May 2010. New York, NY United States: American Thoracic Society. doi: 10.1164/ajrccm-conference.2010.181.1_MeetingAbstracts.A2565
Fraser, J., Nataatmadja, M., Passmore, M., Dunster, K. and Kermeen, F. (2009). Brain Stem Death Induced Pulmonary Hypertension and Bronchiole Damage in an Ovine Model. 29th Annual Meeting and Scientific Session of the International-Society-for-Heart-and-Lung-Transplantation, Paris, France, 22-25 April 2009. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.healun.2008.11.459
Passmore, M., Nataatmadja, M., Russell, F., Corley, A., Venz, E., Hopkins, P., Kermeen, F. and Fraser, J. (2009). The Role of Brain Stem Death and Ischemia Reperfusion Injury in the Alteration of the Endothelin and RAS Pathways Pre and Post Lung Transplantation. 29th Annual Meeting and Scientific Session of the International-Society-for-Heart-and-Lung-Transplantation, Paris, France, 22-25 April 2009. New York, NY United States: Elsevier. doi: 10.1016/j.healun.2008.11.360
Nataatmadja, M., Passmore, M., Corley, A., Venz, F., Hopkins, P., Kemeen, F. and Fraser, J. (2009). Early epithelial remodelling and bronchiolitis obliterans post lung transplantation. 29th Annual Meeting and Scientific Session of the International Society for Heart and Lung Transplantation, Paris, France, 22-25 April 2009. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.healun.2008.11.792
Fraser, J. J., Nataatmadja, M., Passmore, M., Corley, A., Dunster, K., Dunning, J. and Kermeen, F. (2008). Brain stem death induced pulmonary hypertension - More pronounced and prolonged than left ventricular changes in an ovine model. 28th Annual Meeting of the International Society for Heart and Lung Transplantation, Boston, MA United States, 9-12 April 2008. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.healun.2007.11.123
Preprint
Millar, Jonathan E., Wildi, Karin, Bartnikowski, Nicole, Bouquet, Mahe, Hyslop, Kieran, Passmore, Margaret R., Ki, Katrina K., See Hoe, Louise E., Obonyo, Nchafatso G., Neyton, Lucile, Pedersen, Sanne, Rozencwajg, Sacha, Baillie, J. Kenneth, Li Bassi, Gianluigi, Suen, Jacky Y, McAuley, Daniel F. and Fraser, John F. (2020). Characterising pre-clinical sub-phenotypic models of Acute Respiratory Distress Syndrome: an experimental ovine study.