Researcher biography

I am a Research Fellow at the Institute for Molecular Bioscience at the University of Queensland, specialising in systems immunology, data mining, and artificial intelligence. I have made significant contributions to vaccine and biomarker discovery and to defining the molecular basis of host-pathogen immunity.

My academic background includes a Diploma in Physics from La Sapienza University in Italy (2005) and a Ph.D. in Molecular Pathogenesis and Immunology from the University of Perugia, Italy (2011). I have received training from several leading institutions, including Imperial College, LSHTM, the University of Oxford, the Wellcome Trust Sanger Institute, and QIMR Berghofer, where I developed a solid foundation in the analysis of multi-omics data. My work has led to the identification of several malaria vaccine candidates currently under evaluation in pre-clinical trials in a project funded by the National Foundation for Medical Research and Innovation. I recently received an NIH RO1 grant alongside PI Doolan to develop the first T cell-exclusive malaria vaccine.

My current research interests can be divided into five general themes:

1)System-based genomic approaches to inform the rational design of vaccines against complex human pathogens

2) Defining the molecular basis of immune heterogeneity between individuals using a system-based approach

2)Biomarker discovery for EBV-related cancers

3)Epigenetics and host immunity

4)Application of advanced data mining techniques in medical genomics