Dr Geng Wang

Postdoctoral Research Fellow

Institute for Molecular Bioscience

Postdoctoral Research Fellow

Institute for Molecular Bioscience

geng.wang@uq.edu.au

Researcher biography

Dr. Geng Wang is a postdoctoral research fellow specializing in statistical genetics and genetic epidemiology at the Institute for Molecular Bioscience, University of Queensland. His research focuses on the developmental origins of health and diseases, Mendelian randomization, the genetic susceptibility of complex traits and diseases, and the advancement of statistical genetics methodologies. Proficient in bioinformatics, statistical genetics, and clinical research, he has a background in clinical medicine and the biotechnology industry.

Dr. Wang obtained his bachelor's degree in clinical medicine and master's degree in internal medicine from Second Military Medical University (Shanghai, China) in 2012 and 2016, respectively. He served as a resident physician at Changzheng Hospital, affiliated with Second Military Medical University, from 2016 to 2017, specialising in rheumatology, before being promoted to an attending doctor. During his time in Shanghai, he was invited to visit the Translational Research Institute (Australia) twice in 2016 and 2017 for bioinformatics training and collaborative research.

Driven by his growing interest in human genetics, Dr. Wang pursued a Ph.D. in statistical genetics with Professor David Evans at the University of Queensland, which he successfully completed in 2023. Since then, he has continued his research in the aforementioned areas, contributing to the field with his diverse background and expertise.

Publications

Journal Articles (17)

Conference Papers (2)

Thesis (1)

Journal Articles

Wang, Geng, Warrington, Nicole M. and Evans, David M. (2023). Partitioning genetic effects on birthweight at classical human leukocyte antigen loci into maternal and fetal components, using structural equation modelling. International Journal of Epidemiology, 53 (1) dyad142, 1-9. doi: 10.1093/ije/dyad142

Li, Zhixiu, McRae, Allan F., Wang, Geng, Ellis, Jonathan J., Whyte, Jessica, Kenna, Tony J., Brown, Matthew A. and Evans, David M. (2023). Genotype by sex interactions in ankylosing spondylitis. Nature Genetics, 55 (1), 14-16. doi: 10.1038/s41588-022-01250-5

Wang, Geng, Bond, Tom A., Warrington, Nicole M. and Evans, David M. (2022). Birth weight and cardiometabolic risk factors: a discordant twin study in the UK Biobank. Journal of Developmental Origins of Health and Disease, 14 (2) PII S2040174422000538, 1-7. doi: 10.1017/s2040174422000538

Brito Nunes, Caroline, Huang, Peiyuan, Wang, Geng, Lundberg, Mischa, D’Urso, Shannon, Wootton, Robyn E., Borges, Maria Carolina, Lawlor, Deborah A., Warrington, Nicole M., Evans, David M., Hwang, Liang-Dar and Moen, Gunn-Helen (2022). Mendelian randomization study of maternal coffee consumption and its influence on birthweight, stillbirth, miscarriage, gestational age and pre-term birth. International Journal of Epidemiology, 52 (1), 1-13. doi: 10.1093/ije/dyac121

Wang, Geng, Bhatta, Laxmi, Moen, Gunn-Helen, Hwang, Liang-Dar, Kemp, John P., Bond, Tom A., Åsvold, Bjørn Olav, Brumpton, Ben, Evans, David M. and Warrington, Nicole M. (2022). Investigating a potential causal relationship between maternal blood pressure during pregnancy and future offspring cardiometabolic health. Hypertension, 79 (1), 170-177. doi: 10.1161/hypertensionaha.121.17701

Song, Shuang, Shan, Nayang, Wang, Geng, Yan, Xiting, Liu, Jun S and Hou, Lin (2021). Openness weighted association studies: leveraging personal genome information to prioritize noncoding variants. Bioinformatics, 37 (24), 4737-4743. doi: 10.1093/bioinformatics/btab514

Wu, Xin, Zhong, Jia-Yun, Wang, Geng and Xu, Hu-ji (2021). Factors relating to bone mineral density in young and middle-aged patients with ankylosing spondylitis. Chinese Medical Journal, 134 (21), 2556-2563. doi: 10.1097/cm9.0000000000001787

Li, Zhixiu, Wu, Xin, Leo, Paul J., De Guzman, Erika, Akkoc, Nurullah, Breban, Maxime, Macfarlane, Gary J., Mahmoudi, Mahdi, Marzo-Ortega, Helena, Anderson, Lisa K., Wheeler, Lawrie, Chou, Chung-Tei, Harrison, Andrew A., Stebbings, Simon, Jones, Gareth T., Bang, So-Young, Wang, Geng, Jamshidi, Ahmadreza, Farhadi, Elham, Song, Jing, Lin, Li, Li, Mengmeng, Wei, James Cheng-Chung, Martin, Nicholas G., Wright, Margaret J., Lee, MinJae, Wang, Yuqin, Zhan, Jian, Zhang, Jin-San ... Brown, Matthew A. (2021). Correction: Polygenic Risk Scores have high diagnostic capacity in ankylosing spondylitis. Annals of the Rheumatic Diseases, 80 (11), E187-E187. doi: 10.1136/annrheumdis-2020-219446corr1

Wu, Xin, Wang, Geng, Zhang, Luding and Xu, Huji (2021). Genetics of Ankylosing Spondylitis—focusing on the ethnic difference between East Asia and Europe. Frontiers in Genetics, 12 671682, 671682. doi: 10.3389/fgene.2021.671682

Li, Zhixiu, Wu, Xin, Leo, Paul J., De Guzman, Erika, Akkoc, Nurullah, Breban, Maxime, MacFarlane, Gary J., Mahmoudi, Mahdi, Marzo-Ortega, Helena, Anderson, Lisa K., Wheeler, Lawrie, Chou, Chung-Tei, Harrison, Andrew A., Stebbings, Simon, Jones, Gareth T., Bang, So-Young, Wang, Geng, Jamshidi, Ahmadreza, Farhadi, Elham, Song, Jing, Lin, Li, Li, Mengmeng, Wei, James Cheng-Chung, Martin, Nicholas G., Wright, Margaret J., Lee, MinJae, Wang, Yuqin, Zhan, Jian, Zhang, Jin-San ... Brown, Matthew A (2021). Polygenic Risk Scores have high diagnostic capacity in ankylosing spondylitis. Annals of the Rheumatic Diseases, 80 (9) annrheumdis-2020- 219446, annrheumdis-2020. doi: 10.1136/annrheumdis-2020-219446

D'Urso, Shannon, Wang, Geng, Hwang, Liang-Dar, Moen, Gunn-Helen, Warrington, Nicole M. and Evans, David M. (2020). A cautionary note on using Mendelian randomization to examine the Barker hypothesis and Developmental Origins of Health and Disease (DOHaD). Journal of Developmental Origins of Health and Disease, 12 (5), 1-6. doi: 10.1017/S2040174420001105

Hwang, Liang-Dar, Tubbs, Justin D., Luong, Justin, Lundberg, Mischa, Moen, Gunn-Helen, Wang, Geng, Warrington, Nicole M., Sham, Pak C., Cuellar-Partida, Gabriel and Evans, David M. (2020). Estimating indirect parental genetic effects on offspring phenotypes using virtual parental genotypes derived from sibling and half sibling pairs. PLoS Genetics, 16 (10) e1009154, e1009154. doi: 10.1371/journal.pgen.1009154

Moen, Gunn-Helen, Brumpton, Ben, Willer, Cristen, Åsvold, Bjørn Olav, Birkeland, Kåre I., Wang, Geng, Neale, Michael C., Freathy, Rachel M., Smith, George Davey, Lawlor, Deborah A., Kirkpatrick, Robert M., Warrington, Nicole M. and Evans, David M. (2020). Mendelian randomization study of maternal influences on birthweight and future cardiometabolic risk in the HUNT cohort. Nature Communications, 11 (1) 5404, 5404. doi: 10.1038/s41467-020-19257-z

Shi, Xiu-Yu, Wang, Geng, Li, Ting, Li, Zhixiu, Leo, Paul, Liu, Zhisheng, Wu, Gefei, Zhu, Hongmin, Zhang, Yuqin, Li, Dong, Gao, Li, Yang, Liu, Wang, Wei, Liao, Jianxiang, Wang, Jiwen, Zhou, Shuizhen, Wang, Hua, Li, Xiaojing, Gao, Jingyun, Zhang, Li, Shu, Xiaomei, Li, Dan, Li, Yan, Chen, Chunhong, Zhang, Xiuju, Partida, Gabriel Cuellar, Lundberg, Mischa, Reutens, David, Bartlett, Perry ... Xu, Huji (2020). Identification of susceptibility variants to benign childhood epilepsy with centro-temporal spikes (BECTS) in Chinese Han population. EBioMedicine, 57 102840, 102840. doi: 10.1016/j.ebiom.2020.102840

Wang, Geng, Kim, Tae-Hwan, Li, Zhixiu, Cortes, Adrian, Kim, Kwangwoo, Bang, So-Young, Leo, Paul, Brown, Matthew A. and Xu, Huji (2020). MHC associations of ankylosing spondylitis in East Asians are complex and involve non-HLA-B27 HLA contributions. Arthritis Research and Therapy, 22 (1) 74, 1-8. doi: 10.1186/s13075-020-02148-5

Zhou, Ling, Wang, Geng, Liu, Xin, Song, Jing, Chen, Ling and Xu, Huji (2017). Matrix metalloproteinase-3 and the 7-joint ultrasound score in the assessment of disease activity and therapeutic efficacy in patients with moderate to severe rheumatoid arthritis. Arthritis Research & Therapy, 19 (1), 250. doi: 10.1186/s13075-017-1449-z

Wang, Geng, Mu, Rong and Xu, Huji (2015). Management of rheumatoid arthritis in People's Republic of China - focus on tocilizumab and patient considerations. International journal of general medicine, 8, 187-194. doi: 10.2147/IJGM.S81633

Conference Papers

Wang, Geng, Bhatta, Laxmi, Moen, Gunn-Helen, Hwang, Liang-Dar, Kemp, John P., Bond, Tom A., Asvold, Bjorn Olav, Brumpton, Ben, Evans, David M. and Warrington, Nicole M. (2021). Investigating a potential causal relationship between maternal blood pressure during pregnancy and future offspring cardiometabolic health. Behavior Genetics Association 51st Annual Meeting, Online (Zoom), 29 June 2021. New York, United States: Springer.

Lundberg, Mischa, Campos, Adrian I., Farrell, Scott F., Wang, Geng, Sterling, Michele M., Rentería, Miguel E., Ngo, Trung Thanh and Cuéllar-Partida, Gabriel (2020). Genetic, lifestyle and environmental risk factors for chronic pain revealed through GWAS. 50th Annual Meeting of the Behavior Genetics Association, Online, 26 June 2020. NEW YORK: SPRINGER.

Thesis

Wang, Geng (2023). Using Genetics to Understand the Relationship Between the Intrauterine Environment and Future Offspring Cardiometabolic Risk. PhD Thesis, Frazer Institute, The University of Queensland. doi: 10.14264/8edb67a