Dr Nicole Warrington
Senior Research Fellow
Institute for Molecular Bioscience
+61 7 344 37347
Researcher biography
Dr Nicole Warrington is a NHMRC Emerging Leadership Fellow at the University of Queensland Institute for Molecular Bioscience. She has a strong background in statistical genetics and has been actively working towards understanding the genetic determinants of early life growth. Dr Warrington studied a Bachelor of Science at Victoria University in Wellington, New Zealand, majoring in Mathematical Statistics and Psychology. She then completed an honours degree at The University of Western Australia, where she developed a keen interest for genetics, and was subsequently awarded an Australian Postgraduate Award to complete her PhD in statistical genetics and life-course epidemiology. During her PhD she spent time at the University of Toronto to gain experience in statistical modelling methods for longitudinal growth trajectories and conducted the first genome-wide association study of longitudinal growth trajectories over childhood. After completing her PhD, Dr Warrington started at the University of Queensland and focused on using genetics to inform about the relationship between birth weight and cardio-metabolic diseases in later life. She pioneered a new statistical method to partition genetic effects on birth weight into maternal and fetal components, and combined this method with a causal modelling approach, Mendelian randomization. This method was instrumental in demonstrating the relationship between birth weight and adult hypertension is driven by genetic effects, over-turning 30 years of research into the effects of intrauterine programming. More recently, her research focus has broadened to determine whether rapid weight growth across early life, including fetal development, childhood and adolescence, causally increases risk of cardio-metabolic disease and in doing so, hopes to identify optimal times across the life-course where interventions could reduce the incidence of cardio-metabolic diseases.
Book Chapter
Hwang, Liang-Dar, Davies, Neil M., Warrington, Nicole M. and Evans, David M. (2022). Integrating family-based and Mendelian randomization designs. Combining human genetics and causal inference to understand human disease and development. (pp. 137-150) edited by George Davey Smith, Rebecca Richmond and Jean-Baptiste Pingault. Cold Spring Harbor, NY, United States: Cold Spring Harbor Laboratory Press.
Journal Articles
Hwang, Liang-Dar, Cuellar-Partida, Gabriel, Yengo, Loic, Zeng, Jian, Toivonen, Jarkko, Arvas, Mikko, Beaumont, Robin N., Freathy, Rachel M., Moen, Gunn-Helen, Warrington, Nicole M. and Evans, David M. (2024). DINGO: increasing the power of locus discovery in maternal and fetal genome-wide association studies of perinatal traits. Nature Communications, 15 (1) 9255, 9255. doi: 10.1038/s41467-024-53495-9
Warrington, Nicole M, Wang, Geng and Bond, Tom A (2024). Is lower birthweight truly causal for increased cardiovascular risk?. European Heart Journal. doi: 10.1093/eurheartj/ehae509
Lloyd, Rachel, Pirikahu, Sarah, Walter, Jane, Cadby, Gemma, Warrington, Nicole, Perera, Dilukshi, Hickey, Martha, Saunders, Christobel, Hackmann, Michael, Sampson, David D., Shepherd, John, Lilge, Lothar and Stone, Jennifer (2024). The Prospective Association between Early Life Growth and Breast Density in Young Adult Women. Cancers, 16 (13) 2418, 2418. doi: 10.3390/cancers16132418
Moksnes, Marta R., Hansen, Ailin F., Wolford, Brooke N., Thomas, Laurent F., Rasheed, Humaira, Simić, Anica, Bhatta, Laxmi, Brantsæter, Anne Lise, Surakka, Ida, Zhou, Wei, Magnus, Per, Njølstad, Pål R., Andreassen, Ole A., Syversen, Tore, Zheng, Jie, Fritsche, Lars G., Evans, David M., Warrington, Nicole M., Nøst, Therese H., Åsvold, Bjørn Olav, Flaten, Trond Peder, Willer, Cristen J., Hveem, Kristian and Brumpton, Ben M. (2024). A genome-wide association study provides insights into the genetic etiology of 57 essential and non-essential trace elements in humans. Communications Biology, 7 (1) 432, 432. doi: 10.1038/s42003-024-06101-z
Pagoni, Panagiota, Higgins, Julian P. T., Lawlor, Deborah A., Stergiakouli, Evie, Warrington, Nicole M., Morris, Tim T. and Tilling, Kate (2024). Meta-regression of genome-wide association studies to estimate age-varying genetic effects. European Journal of Epidemiology, 39 (3), 257-270. doi: 10.1007/s10654-023-01086-1
Thompson, W. D., Reynolds, R. M., Beaumont, R. N., Warrington, N. M., Tyrrell, J., Wood, A. R., Evans, D. M., McDonald, T. J., Hattersley, A. H., Freathy, R. M., Lawlor, D. A. and Borges, M. C. (2024). Maternal plasma cortisol’s effect on offspring birth weight: a Mendelian Randomisation study. BMC Pregnancy and Childbirth, 24 (1) 65, 1-11. doi: 10.1186/s12884-024-06250-3
Power, Grace M., Sanderson, Eleanor, Pagoni, Panagiota, Fraser, Abigail, Morris, Tim, Prince, Claire, Frayling, Timothy M., Heron, Jon, Richardson, Tom G., Richmond, Rebecca, Tyrrell, Jessica, Warrington, Nicole, Davey Smith, George, Howe, Laura D. and Tilling, Kate M. (2024). Methodological approaches, challenges, and opportunities in the application of Mendelian randomisation to lifecourse epidemiology: A systematic literature review. European Journal of Epidemiology, 39 (5), 501-520. doi: 10.1007/s10654-023-01032-1
Wang, Geng, Warrington, Nicole M. and Evans, David M. (2023). Partitioning genetic effects on birthweight at classical human leukocyte antigen loci into maternal and fetal components, using structural equation modelling. International Journal of Epidemiology, 53 (1) dyad142, 1-9. doi: 10.1093/ije/dyad142
Zhao, Jian, Stewart, Isobel D., Baird, Denis, Mason, Dan, Wright, John, Zheng, Jie, Gaunt, Tom R., Evans, David M., Freathy, Rachel M., Langenberg, Claudia, Warrington, Nicole M., Lawlor, Deborah A. and Borges, Maria Carolina (2023). Causal effects of maternal circulating amino acids on offspring birthweight: a Mendelian randomisation study. eBioMedicine, 88 104441, 1-14. doi: 10.1016/j.ebiom.2023.104441
Decina, Caitlin S., Hopkins, Rhian, Bowden, Jack, Shields, Beverly M., Lawlor, Deborah A., Warrington, Nicole M., Evans, David M., Freathy, Rachel M. and Beaumont, Robin N. (2023). Investigating a possible causal relationship between maternal serum urate concentrations and offspring birthweight: a Mendelian randomization study. International Journal of Epidemiology, 52 (1), 178-189. doi: 10.1093/ije/dyac186
Moen, Gunn-Helen, Nivard, Michel, Bhatta, Laxmi, Warrington, Nicole M., Willer, Cristen, Åsvold, Bjørn Olav, Brumpton, Ben and Evans, David M. (2022). Using genomic structural equation modeling to partition the genetic covariance between birthweight and cardiometabolic risk factors into maternal and offspring components in the Norwegian HUNT study. Behavior Genetics, 53 (1), 1-13. doi: 10.1007/s10519-022-10116-9
D’Urso, Shannon, Arumugam, Pooja, Weider, Therese, Hwang, Liang-Dar, Bond, Tom A., Kemp, John P., Warrington, Nicole M., Evans, David M., O’Mara, Tracy A. and Moen, Gunn-Helen (2022). Mendelian randomization analysis of factors related to ovulation and reproductive function and endometrial cancer risk. BMC Medicine, 20 (1) 419, 1-17. doi: 10.1186/s12916-022-02585-w
Wang, Geng, Bond, Tom A., Warrington, Nicole M. and Evans, David M. (2022). Birth weight and cardiometabolic risk factors: a discordant twin study in the UK Biobank. Journal of Developmental Origins of Health and Disease, 14 (2) PII S2040174422000538, 1-7. doi: 10.1017/s2040174422000538
Brito Nunes, Caroline, Huang, Peiyuan, Wang, Geng, Lundberg, Mischa, D’Urso, Shannon, Wootton, Robyn E., Borges, Maria Carolina, Lawlor, Deborah A., Warrington, Nicole M., Evans, David M., Hwang, Liang-Dar and Moen, Gunn-Helen (2022). Mendelian randomization study of maternal coffee consumption and its influence on birthweight, stillbirth, miscarriage, gestational age and pre-term birth. International Journal of Epidemiology, 52 (1), 1-13. doi: 10.1093/ije/dyac121
Wang, Geng, Bhatta, Laxmi, Moen, Gunn-Helen, Hwang, Liang-Dar, Kemp, John P., Bond, Tom A., Åsvold, Bjørn Olav, Brumpton, Ben, Evans, David M. and Warrington, Nicole M. (2022). Investigating a potential causal relationship between maternal blood pressure during pregnancy and future offspring cardiometabolic health. Hypertension, 79 (1), 170-177. doi: 10.1161/hypertensionaha.121.17701
Thompson, William D., Beaumont, Robin N., Kuang, Alan, Warrington, Nicole M., Ji, Yingjie, Tyrrell, Jess, Wood, Andrew R., Scholtens, Denise, Knight, Bridget A., Evans, David M., Lowe, Bill L., Santorelli, Gillian, Azad, Raq, Mason, Dan, Hattersley, Andrew T., Frayling, Timothy M., Yaghootkar, Hanieh, Borges, Maria-Carolina, Lawlor, Deborah A. and Freathy, Rachel M. (2021). Fetal alleles predisposing to metabolically favourable adiposity are associated with higher birth weight. Human Molecular Genetics, 31 (11), 1762-1775. doi: 10.1093/hmg/ddab356
Thompson, William D., Beaumont, Robin N., Kuang, Alan, Warrington, Nicole M., Ji, Yingjie, Tyrrell, Jessica, Wood, Andrew R., Scholtens, Denise M., Knight, Bridget A., Evans, David M., Lowe, William L., Santorelli, Gillian, Azad, Rafaq, Mason, Dan, Hattersley, Andrew T., Frayling, Timothy M., Yaghootkar, Hanieh, Borges, Maria Carolina, Lawlor, Deborah A. and Freathy, Rachel M. (2021). Higher maternal adiposity reduces offspring birthweight if associated with a metabolically favourable profile. Diabetologia, 64 (12), 2790-2802. doi: 10.1007/s00125-021-05570-9
Warrington, Nicole M., Hwang, Liang-Dar, Nivard, Michel G. and Evans, David M. (2021). Estimating direct and indirect genetic effects on offspring phenotypes using genome-wide summary results data. Nature Communications, 12 (1) 5420, 1-12. doi: 10.1038/s41467-021-25723-z
Moen, Gunn-Helen, Beaumont, Robin N., Grarup, Niels, Sommer, Christine, Shields, Beverley M., Lawlor, Deborah A., Freathy, Rachel M., Evans, David M. and Warrington, Nicole M. (2020). Investigating the causal effect of maternal vitamin B12 and folate levels on offspring birthweight. International Journal of Epidemiology, 50 (1), 179-189. doi: 10.1093/ije/dyaa256
D'Urso, Shannon, Wang, Geng, Hwang, Liang-Dar, Moen, Gunn-Helen, Warrington, Nicole M. and Evans, David M. (2020). A cautionary note on using Mendelian randomization to examine the Barker hypothesis and Developmental Origins of Health and Disease (DOHaD). Journal of Developmental Origins of Health and Disease, 12 (5) PII S2040174420001105, 1-6. doi: 10.1017/S2040174420001105
Hwang, Liang-Dar, Tubbs, Justin D., Luong, Justin, Lundberg, Mischa, Moen, Gunn-Helen, Wang, Geng, Warrington, Nicole M., Sham, Pak C., Cuellar-Partida, Gabriel and Evans, David M. (2020). Estimating indirect parental genetic effects on offspring phenotypes using virtual parental genotypes derived from sibling and half sibling pairs. PLoS Genetics, 16 (10) e1009154, e1009154. doi: 10.1371/journal.pgen.1009154
Moen, Gunn-Helen, Brumpton, Ben, Willer, Cristen, Åsvold, Bjørn Olav, Birkeland, Kåre I., Wang, Geng, Neale, Michael C., Freathy, Rachel M., Smith, George Davey, Lawlor, Deborah A., Kirkpatrick, Robert M., Warrington, Nicole M. and Evans, David M. (2020). Mendelian randomization study of maternal influences on birthweight and future cardiometabolic risk in the HUNT cohort. Nature Communications, 11 (1) 5404, 5404. doi: 10.1038/s41467-020-19257-z
Cuellar-Partida, Gabriel, Tung, Joyce Y., Eriksson, Nicholas, Albrecht, Eva, Aliev, Fazil, Andreassen, Ole A., Barroso, Inês, Beckmann, Jacques S., Boks, Marco P., Boomsma, Dorret I., Boyd, Heather A., Breteler, Monique M. B., Campbell, Harry, Chasman, Daniel I., Cherkas, Lynn F., Davies, Gail, de Geus, Eco J. C., Deary, Ian J., Deloukas, Panos, Dick, Danielle M., Duffy, David L., Eriksson, Johan G., Esko, Tõnu, Feenstra, Bjarke, Geller, Frank, Gieger, Christian, Giegling, Ina, Gordon, Scott D., Han, Jiali ... Medland, Sarah E. (2020). Genome-wide association study identifies 48 common genetic variants associated with handedness. Nature Human Behaviour, 5 (1), 59-70. doi: 10.1038/s41562-020-00956-y
Zheng, Jie, Brion, Marie-Jo, Kemp, John P., Warrington, Nicole M., Borges, Maria-Carolina, Hemani, Gibran, Richardson, Tom G., Rasheed, Humaira, Qiao, Zhen, Haycock, Philip, Ala-Korpela, Mika, Davey Smith, George, Tobias, Jon H. and Evans, David M. (2020). The effect of plasma lipids and lipid-lowering interventions on bone mineral density: a Mendelian randomization study. Journal of Bone and Mineral Research, 35 (7) jbmr.3989, 1224-1235. doi: 10.1002/jbmr.3989
Hwang, Liang-Dar, Davies, Neil M., Warrington, Nicole M. and Evans, David M. (2020). Integrating family-based and Mendelian randomization designs. Cold Spring Harbor Perspectives in Medicine, 11 (3) a039503, 1-15. doi: 10.1101/cshperspect.a039503
Qiao, Zhen, Zheng, Jie, Helgeland, Øyvind, Vaudel, Marc, Johansson, Stefan, Njølstad, Pål R., Smith, George Davey, Warrington, Nicole M. and Evans, David M. (2019). Introducing M-GCTA a software package to estimate maternal (or paternal) genetic effects on offspring phenotypes. Behavior Genetics, 50 (1), 51-66. doi: 10.1007/s10519-019-09969-4
Couto Alves, Alexessander, De Silva, N. Maneka G., Karhunen, Ville, Sovio, Ulla, Das, Shikta, Taal, H. Rob, Warrington, Nicole M., Lewin, Alexandra M., Kaakinen, Marika, Cousminer, Diana L., Thiering, Elisabeth, Timpson, Nicholas J., Bond, Tom A., Lowry, Estelle, Brown, Christopher D., Estivill, Xavier, Lindi, Virpi, Bradfield, Jonathan P., Geller, Frank, Speed, Doug, Coin, Lachlan J. M., Loh, Marie, Barton, Sheila J., Beilin, Lawrence J., Bisgaard, Hans, Bønnelykke, Klaus, Alili, Rohia, Hatoum, Ida J., Schramm, Katharina ... Early Growth Genetics (EGG) Consortium (2019). GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI. Science Advances, 5 (9) eaaw3095, eaaw3095. doi: 10.1126/sciadv.aaw3095
Hwang, Liang-Dar, Lawlor, Deborah A., Freathy, Rachel M., Evans, David M. and Warrington, Nicole M. (2019). Using a two-sample Mendelian randomization design to investigate a possible causal effect of maternal lipid concentrations on offspring birth weight. International Journal of Epidemiology, 48 (5), 1457-1467. doi: 10.1093/ije/dyz160
Warrington, Nicole M., Beaumont, Robin N., Horikoshi, Momoko, Day, Felix R., Helgeland, Øyvind, Laurin, Charles, Bacelis, Jonas, Peng, Shouneng, Hao, Ke, Feenstra, Bjarke, Wood, Andrew R., Mahajan, Anubha, Tyrrell, Jessica, Robertson, Neil R., Rayner, N. William, Qiao, Zhen, Moen, Gunn-Helen, Vaudel, Marc, Marsit, Carmen J., Chen, Jia, Nodzenski, Michael, Schnurr, Theresia M., Zafarmand, Mohammad H., Bradfield, Jonathan P., Grarup, Niels, Kooijman, Marjolein N., Li-Gao, Ruifang, Geller, Frank, Paternoster, Lavinia ... Freathy, Rachel M. (2019). Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors. Nature Genetics, 51 (5), 804-814. doi: 10.1038/s41588-019-0403-1
Evans, David M., Moen, Gunn-Helen, Hwang, Liang-Dar, Lawlor, Debbie A. and Warrington, Nicole M. (2019). Elucidating the role of maternal environmental exposures on offspring health and disease using two-sample Mendelian randomization. International Journal of Epidemiology, 48 (3), 861-875. doi: 10.1093/ije/dyz019
Hartwig, Fernando Pires, Davies, Neil Martin, Horta, Bernardo Lessa, Ahluwalia, Tarunveer S., Bisgaard, Hans, Bønnelykke, Klaus, Caspi, Avshalom, Moffitt, Terrie E., Poulton, Richie, Sajjad, Ayesha, Tiemeier, Henning W., Dalmau-Bueno, Albert, Guxens, Mònica, Bustamante, Mariona, Santa-Marina, Loreto, Parker, Nadine, Paus, Tomáš, Pausova, Zdenka, Lauritzen, Lotte, Schnurr, Theresia M., Michaelsen, Kim F., Hansen, Torben, Oddy, Wendy, Pennell, Craig E., Warrington, Nicole M., Davey Smith, George and Victora, Cesar Gomes (2019). Effect modification of FADS2 polymorphisms on the association between breastfeeding and intelligence: results from a collaborative meta-analysis. International Journal of Epidemiology, 48 (1), 45-57. doi: 10.1093/ije/dyy273
Moen, Gunn-Helen, Hemani, Gibran, Warrington, Nicole M. and Evans, David M. (2019). Calculating Power to Detect Maternal and Offspring Genetic Effects in Genetic Association Studies. Behavior Genetics, 49 (3), 327-339. doi: 10.1007/s10519-018-9944-9
Hayward, Tanisha A., Zhu, Gu, Warrington, Nicole M., Wong, Yide, Ryan, Rachael Y.M., Murray, Abella M., Haigh, Oscar, Martin, Nicholas G., Miles, John J. and Evans, David M. (2018). Antibody response to common human viruses is shaped by genetic factors. Journal of Allergy and Clinical Immunology, 143 (4), 1640-1643. doi: 10.1016/j.jaci.2018.11.039
Warrington, Nicole M., Shevroja, Enisa, Hemani, Gibran, Hysi, Pirro G., Jiang, Yunxuan, Auton, Adam, Boer, Cindy G., Mangino, Massimo, Wang, Carol A., Kemp, John P., McMahon, George, Medina-Gomez, Carolina, Hickey, Martha, Trajanoska, Katerina, Wolke, Dieter, Ikram, Arfan M., 23 and Me Research Team, Montgomery, Grant W., Felix, Janine F., Wright, Margaret J., Mackey, David A., Jaddoe, Vincent W., Martin, Nicholas G., Tung, Joyce Y., Davey Smith, George, Pennell, Craig E., Spector, Tim D., van Meurs, Joyce, Rivadeneira, Fernando ... Evans, David M. (2018). Genome-wide association study identifies nine novel loci for 2D:4D finger ratio, a putative retrospective biomarker of testosterone exposure in utero. Human Molecular Genetics, 27 (11), 2025-2038. doi: 10.1093/hmg/ddy121
Beaumont, Robin N., Warrington, Nicole M., Cavadino, Alana, Tyrrell, Jessica, Nodzenski, Michael, Horikoshi, Momoko, Geller, Frank, Myhre, Ronny, Richmond, Rebecca C., Paternoster, Lavinia, Bradfield, Jonathan P., Kreiner-Møller, Eskil, Huikari, Ville, Metrustry, Sarah, Lunetta, Kathryn L., Painter, Jodie N., Hottenga, Jouke-Jan, Allard, Catherine, Barton, Sheila J., Espinosa, Ana, Marsh, Julie A., Potter, Catherine, Zhang, Ge, Ang, Wei, Berry, Diane J., Bouchard, Luigi, Das, Shikta, Early Growth Genetics (EGG) Consortium, Hakonarson, Hakon ... Freathy, Rachel M. (2018). Genome-wide association study of offspring birth weight in 86,577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics. Human Molecular Genetics, 27 (4) ddx429, 742-756. doi: 10.1093/hmg/ddx429
Warrington, Nicole M., Freathy, Rachel M., Neale, Michael C. and Evans, David M. (2018). Using structural equation modelling to jointly estimate maternal and fetal effects on birthweight in the UK Biobank. International Journal of Epidemiology, 47 (4), 1229-1241. doi: 10.1093/ije/dyy015
Warrington, N. M., Richmond, R., Fenstra, B., Myhre, R., Gaillard, R., Paternoster, L., Wang, C. A., Beaumont, R. N., Das, S., Murcia, M., Barton, S. J., Espinosa, A., Thiering, E., Atalay, M., Pitkänen, N., Ntalla, I., Jonsson, A. E., Freathy, R., Karhunen, V., Tiesler, C. M. T., Allard, C., Crawford, A., Ring, S. M., Melbye, M., Magnus, P., Rivadeneira, F., Skotte, L., Hansen, T., Marsh, J. ... Lawlor, D. A. (2017). Maternal and fetal genetic contribution to gestational weight gain. International Journal of Obesity (2005), 42 (4), 775-784. doi: 10.1038/ijo.2017.248
Kemp, John P., Morris, John A., Medina-Gomez, Carolina, Forgetta, Vincenzo, Warrington, Nicole M., Youlten, Scott E., Zheng, Jie, Gregson, Celia L., Grundberg, Elin, Trajanoska, Katerina, Logan, John G., Pollard, Andrea S., Sparkes, Penny C., Ghirardello, Elena J., Allen, Rebecca, Leitch, Victoria D., Butterfield, Natalie C., Komla-Ebri, Davide, Adoum, Anne-Tounsia, Curry, Katharine F., White, Jacqueline K., Kussy, Fiona, Greenlaw, Keelin M., Xu, Changjiang, Harvey, Nicholas C., Cooper, Cyrus, Adams, David J., Greenwood, Celia M. T., Maurano, Matthew T. ... Evans, David M. (2017). Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis. Nature Genetics, 49 (10), 1468-1475. doi: 10.1038/ng.3949
Willems, Sara M., Wright, Daniel J., Day, Felix R., Trajanoska, Katerina, Joshi, Peter K., Morris, John A., Matteini, Amy M., Garton, Fleur C., Grarup, Niels, Oskolkov, Nikolay, Thalamuthu, Anbupalam, Mangino, Massimo, Liu, Jun, Demirkan, Ayse, Lek, Monkol, Xu, Liwen, Wang, Guan, Oldmeadow, Christopher, Gaulton, Kyle J., Lotta, Luca A., Miyamoto-Mikami, Eri, Rivas, Manuel A., White, Tom, Loh, Po-Ru, Aadahl, Mette, Amin, Najaf, Attia, John R., Austin, Krista, Benyamin, Beben ... Ohlsson, Claes (2017). Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness. Nature Communications, 8 (1) 16015, 16015. doi: 10.1038/ncomms16015
Lawlor, Deborah, Richmond, Rebecca, Warrington, Nicole , McMahon, George, Davery Smith, George, Bowden, Jack and Evans, David M. (2017). Using Mendelian randomization to determine causal effects of maternal pregnancy (intrauterine) exposures on offspring outcomes: Sources of bias and methods for assessing them. Wellcome Open Research, 2 (11) 11, 11. doi: 10.12688/wellcomeopenres.10567.1
Kreiner, Eskil, Waage, Johannes, Standl, Marie, Brix, Susanne, Pers, Tune H., Couto Alves, Alexessander, Warrington, Nicole M., Tiesler, Carla M. T., Fuertes, Elaine, Franke, Lude, Hirschhorn, Joel N., James, Alan, Simpson, Angela, Tung, Joyce Y., Koppelman, Gerard H., Postma, Dirkje S., Pennell, Craig E., Jarvelin, Marjo-Riitta, Custovic, Adnan, Timpson, Nicholas, Ferreira, Manuel A., Strachan, David P., Henderson, John, Hinds, David, Bisgaard, Hans and Bønnelykke, Klaus (2017). Shared genetic variants suggest common pathways in allergy and autoimmune diseases. Allergy: European Journal of Allergy and Clinical Immunology, 140 (3), 771-781. doi: 10.1016/j.jaci.2016.10.055
Zheng, Jie, Erzurumluoglu, A. Mesut, Elsworth, Benjamin L., Kemp, John P., Howe, Laurence, Haycock, Philip C., Hemani, Gibran, Tansey, Katherine, Laurin, Charles, St Pourcain, Beate, Warrington, Nicole M., Finucane, Hilary K., Price, Alkes L., Bulik-Sullivan, Brendan K., Anttila, Verneri, Paternoster, Lavinia, Gaunt, Tom R., Evans, David M. and Neale, Benjamin M. (2017). LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis. Bioinformatics, 33 (2), 272-279. doi: 10.1093/bioinformatics/btw613
Horikoshi, Momoko, Beaumont, Robin N., Day, Felix R., Warrington, Nicole M., Kooijman, Marjolein N., Fernandez-Tajes, Juan, Feenstra, Bjarke, van Zuydam, Natalie R., Gaulton, Kyle J., Grarup, Niels, Bradfield, Jonathan P., Strachan, David P., Li-Gao, Ruifang, Ahluwalia, Tarunveer S., Kreiner, Eskil, Rueedi, Rico, Lyytikainen, Leo-Pekka, Cousminer, Diana L., Wu, Ying, Thiering, Elisabeth, Wang, Carol A., Have, Christian T., Hottenga, Jouke-Jan, Vilor-Tejedor, Natalia, Joshi, Peter K., Boh, Eileen Tai Hui, Ntalla, Ioanna, Pitkanen, Niina, Mahajan, Anubha ... Freathy, Rachel M. (2016). Genome-wide associations for birth weight and correlations with adult disease. Nature, 538 (7624), 248-252. doi: 10.1038/nature19806
Warrington, Nicole M., Kemp, John P., Tilling, Kate, Tobias, Jonathan H. and Evans, David M. (2015). Genetic variants in adult bone mineral density and fracture risk genes are associated with the rate of bone mineral density acquisition in adolescence. Human Molecular Genetics, 24 (14) ddv143, 4158-4166. doi: 10.1093/hmg/ddv143
Warrington, Nicole M., Howe, Laura D., Paternoster, Lavinia, Kaakinen, Marika, Herrala, Sauli, Huikari, Ville, Wu, Yan Yan, Kemp, John P., Timpson, Nicholas J., Pourcain, Beate St, Smith, George Davey, Tilling, Kate, Jarvelin, Marjo-Riitta, Pennell, Craig E., Evans, David M., Lawlor, Debbie A., Briollais, Laurent and Palmer, Lyle J. (2015). A genome-wide association study of body mass index across early life and childhood. International Journal of Epidemiology, 44 (2) dyv077, 700-712. doi: 10.1093/ije/dyv077
Warrington, Nicole M., Zhu, Gu, Dy, Veronica, Heath, Andrew C., Madden, Pamela A. F., Hemani, Gibran, Kemp, John P., Mcmahon, George, St Pourcain, Beate, Timpson, Nicholas J., Taylor, Caroline M., Golding, Jean, Lawlor, Debbie A., Steer, Colin, Montgomery, Grant W., Martin, Nicholas G., Smith, George Davey, Evans, David M. and Whitfield, John B. (2015). Genome-wide association study of blood lead shows multiple associations near ALAD. Human Molecular Genetics, 24 (13) ddv112, 3871-3879. doi: 10.1093/hmg/ddv112
Costello, Mary-Ellen, Ciccia, Francesco, Willner, Dana, Warrington, Nicole, Robinson, Philip C., Gardiner, Brooke, Marshall, Mhairi, Kenna, Tony J., Triolo. Giovanni and Brown, Matthew A. (2015). Brief report: intestinal dysbiosis in ankylosing spondylitis. Arthritis and Rheumatology, 67 (3), 686-691. doi: 10.1002/art.38967
van der Valk, Ralf J. P., Kreiner-Moller, Eskil, Kooijman, Marjolein N., Guxens, Monica, Stergiakouli, Evangelia, Saaf, Annika, Bradfield, Jonathan P., Geller, Frank, Hayes, M. Geoffrey, Cousminer, Diana L., Koerner, Antje, Thiering, Elisabeth, Curtin, John A., Myhre, Ronny, Huikari, Ville, Joro, Raimo, Kerkhof, Marjan, Warrington, Nicole M., Pitkanen, Niina, Ntalla, Ioanna, Horikoshi, Momoko, Veijola, Riitta, Freathy, Rachel M., Teo, Yik-Ying, Barton, Sheila J., Evans, David M., Kemp, John P., St Pourcain, Beate, Ring, Susan M. ... for the Early Growth Genetics (EGG) Consortium (2015). A novel common variant in DCST2 is associated with length in early life and height in adulthood. Human Molecular Genetics, 24 (4) ddu510, 1155-1168. doi: 10.1093/hmg/ddu510
Warrington, Nicole M., Tilling, Kate, Howe, Laura D., Paternoster, Lavinia, Pennell, Craig E., Wu, Yan Yan and Briollais, Laurent (2014). Robustness of the linear mixed effects model to error distribution assumptions and the consequences for genome-wide association studies. Statistical Applications in Genetics and Molecular Biology, 13 (5), 567-587. doi: 10.1515/sagmb-2013-0066
St Pourcain, Beate, Cents, Rolieke A. M., Whitehouse, Andrew J. O., Haworth, Claire M. A., Davis, Oliver S. P., O'Reilly, Paul F., Roulstone, Susan, Wren, Yvonne, Ang, Qi W., Velders, Fleur P., Evans, David M., Kemp, John P., Warrington, Nicole M., Miller, Laura, Timpson, Nicholas J., Ring, Susan M., Verhulst, Frank C., Hofman, Albert, Rivadeneira, Fernando, Meaburn, Emma L., Price, Thomas S., Dale, Philip S., Pillas, Demetris, Yliherva, Anneli, Rodriguez, Alina, Golding, Jean, Jaddoe, Vincent W. V., Jarvelin, Marjo-Riitta, Plomin, Robert ... Smith, George Davey (2014). Common variation near ROBO2 is associated with expressive vocabulary in infancy. Nature Communications, 5 (1) A4831, 1-9. doi: 10.1038/ncomms5831
Cousminer, Diana L., Stergiakouli, Evangelia, Berry, Diane J., Ang, Wei, Groen-Blokhuis, Maria M., Koerner, Antje, Siitonen, Niina, Ntalla, Ioanna, Marinelli, Marcella, Perry, John R. B., Kettunen, Johannes, Jansen, Rick, Surakka, Ida, Timpson, Nicholas J., Ring, Susan, Mcmahon, George, Power, Chris, Wang, Carol, Kahonen, Mika, Viikari, Jorma, Lehtimaki, Terho, Middeldorp, Christel M., Pol, Hilleke E. Hulshoff, Neef, Madlen, Weise, Sebastian, Pahkala, Katja, Niinikoski, Harri, Zeggini, Eleftheria, Panoutsopoulou, Kalliope ... Warrington, Nicole M. (2014). Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty. Human Molecular Genetics, 23 (16) ddu150, 4452-4464. doi: 10.1093/hmg/ddu150
Kemp, John P., Medina-Gomez, Carolina, Estrada, Karol, St Pourcain, Beate, Heppe, Denise H. M., Warrington, Nicole M., Oei, Ling, Ring, Susan M., Kruithof, Claudia J., Timpson, Nicholas J., Wolber, Lisa E., Reppe, Sjur, Gautvik, Kaare, Grundberg, Elin, Ge, Bing, van der Eerden, Bram, van de Peppel, Jeroen, Hibbs, Matthew A., Ackert-Bicknell, Cheryl L., Choi, Kwangbom, Koller, Daniel L., Econs, Michael J., Williams, Frances M. K., Foroud, Tatiana, Carola Zillikens, M., Ohlsson, Claes, Hofman, Albert, Uitterlinden, Andre G., Davey Smith, George ... Evans, David M. (2014). Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment. PLoS Genetics, 10 (6) e1004423, 1-18. doi: 10.1371/journal.pgen.1004423
Warrington, Nicole M., Howe, Laura D., Wu, Yan Yan, Timpson, Nicholas J., Tilling, Kate, Pennell, Craig E., Newnham, John, Davey-Smith, George, Palmer, Lyle J., Beilin, Lawrence J., Lye, Stephen J., Lawlor, Debbie A. and Briollais, L. (2013). Association of a body mass index genetic risk score with growth throughout childhood and adolescence. PLoS One, 8 (11) e79547, e79547. doi: 10.1371/journal.pone.0079547
Fernández-Rhodes, Lindsay, Demerath, Ellen W., Cousminer, Diana L., Tao, Ran, Dreyfus, Jill G., Esko, Tõnu, Smith, Albert V., Gudnason, Vilmundur, Harris, Tamara B., Launer, Lenore, McArdle, Patrick F., Yerges-Armstrong, Laura M., Elks, Cathy E., Strachan, David P., Kutalik, Zoltán, Vollenweider, Peter, Feenstra, Bjarke, Boyd, Heather A., Metspalu, Andres, Mihailov, Evelin, Broer, Linda, Zillikens, M. Carola, Oostra, Ben, van Duijn, Cornelia M., Lunetta, Kathryn L., Perry, John R. B., Murray, Anna, Koller, Daniel L., Lai, Dongbing ... Franceschini, Nora (2013). Association of adiposity genetic variants with menarche timing in 92,105 women of European descent. American Journal of Epidemiology, 178 (3), 451-460. doi: 10.1093/aje/kws473
Bønnelykke, Klaus, Matheson, Melanie C., Pers, Tune H., Granell, Raquel, Strachan, David P., Alves, Alexessander Couto, Linneberg, Allan, Curtin, John A., Warrington, Nicole M., Standl, Marie, Kerkhof, Marjan, Jonsdottir, Ingileif, Bukvic, Blazenka K., Kaakinen, Marika, Sleimann, Patrick, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Schramm, Katharina, Baltic, Svetlana, Kreiner-Møller, Eskil, Simpson, Angela, St Pourcain, Beate, Coin, Lachlan, Hui, Jennie, Walters, Eugene H., Tiesler, Carla M. T., Duffy, David L., Jones, Graham, Ring, Susan M. ... Brown, Matthew A. (2013). Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization. Nature Genetics, 45 (8), 902-906. doi: 10.1038/ng.2694
Cousminer D.L., Berry D.J., Timpson N.J., Ang W., Thiering E., Byrne E.M., Rob Taal H., Huikari V., Bradfield J.P., Kerkhof M., Groen-Blokhuis M.M., Kreiner-Moller E., Marinelli M., Holst C., Leinonen J.T., Perry J.R.B., Surakka I., Pietilainen O., Kettunen J., Anttila V., Kaakinen M., Sovio U., Pouta A., Das S., Lagou V., Power C., Prokopenko I., Evans D.M., Kemp J.P. ... Middeldorp, Christel (2013). Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity. Human Molecular Genetics, 22 (13), 2735-2747. doi: 10.1093/hmg/ddt104
Taal, H. Rob, St Pourcain, Beate, Thiering, Elisabeth, Das, Shikta, Mook-Kanamori, Dennis O., Warrington, Nicole M., Kaakinen, Marika, Kreiner-Moller, Eskil, Bradfield, Jonathan P., Freathy, Rachel M., Geller, Frank, Guxens, Monica, Cousminer, Diana L., Kerkhof, Marjan, Timpson, Nicholas J., Ikram, M. Arfan, Beilin, Lawrence J., Bonnelykke, Klaus, Buxton, Jessica L., Charoen, Pimphen, Chawes, Bo Lund Krogsgaard, Eriksson, Johan, Evans, David M., Hofman, Albert, Kemp, John P., EKim, Cecilia, Klopp, Norman, Lahti, Jari, Lye, Stephen J. ... Jaddoe, Vincent W. V. (2013). Corrigendum: Common variants at 12q15 and 12q24 are associated with infant head circumference (vol 44, pg 532, 2012). Nature Genetics, 45 (6), 713-713. doi: 10.1038/ng0613-713a
Peters, Kirsten E., Beilby, John, Cadby, Gemma, Warrington, Nicolen M., Bruce, David G., Davis, Wendy A., Davis, Timothy M. E., Wiltshire, Steven, Knuiman, Matthew, McQuillan, Brendan M., Palmer, Lyle J., Thompson, Peter L. and Hung, Joseph (2013). A comprehensive investigation of variants in genes encoding adiponectin (ADIPOQ) and its receptors (ADIPOR1/R2), and their association with serum adiponectin, type 2 diabetes, insulin resistance and the metabolic syndrome. BMC Medical Genetics, 14 (1) 15. doi: 10.1186/1471-2350-14-15
Warrington, Nicole M., Wu, Yan Yan, Pennell, Craig E., Marsh, Julie A., Beilin, Lawrence J., Palmer, Lyle J., Lye, Stephen J. and Briollais, Laurent (2013). Modelling BMI trajectories in children for genetic association studies. PLoS One, 8 (1) e53897, e53897. doi: 10.1371/journal.pone.0053897
St Pourcain, Beate, Whitehouse, Andrew J. O., Ang, Wei Q., Warrington, Nicole M., Glessner, Joseph T., Wang, Kai, Timpson, Nicholas J., Evans, David M., Kemp, John P., Ring,Susan M., McArdle, Wendy L., Golding, Jean, Hakonarson, Hakon, Pennell, Craig E. and Smith, George Davey (2013). Common variation contributes to the genetic architecture of social communication traits. Molecular Autism, 4 (1) 34, 34.1-34.12. doi: 10.1186/2040-2392-4-34
Howe, Laura D., Parmar, Priyakumari G., Paternoster, Lavinia, Warrington, Nicole M., Kemp, John P., Briollais, Laurent, Newnham, John P., Timpson, Nicholas J., Smith, George D., Ring, Susan M., Evans, David M., Tilling, Kate, Pennell, Craig E., Beilin, Lawrie J., Palmer, Lyle J. and Lawlor, Debbie A. (2013). Genetic influences on trajectories of systolic blood pressure across childhood and adolescence. Circulation: Cardiovascular Genetics, 6 (6), 608-614. doi: 10.1161/CIRCGENETICS.113.000197
Horikoshi M., Yaghootkar H., Mook-Kanamori D.O., Sovio U., Taal H.R., Hennig B.J., Bradfield J.P., St Pourcain B., Evans D.M., Charoen P., Kaakinen M., Cousminer D.L., Lehtimaki T., Kreiner-Moller E., Warrington N.M., Bustamante M., Feenstra B., Berry D.J., Thiering E., Pfab T., Barton S.J., Shields B.M., Kerkhof M., Van Leeuwen E.M., Fulford A.J., Kutalik Z., Zhao J.H., Den Hoed M., Mahajan A. ... Freathy R.M. (2013). New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism. Nature Genetics, 45 (1), 76-82. doi: 10.1038/ng.2477
Boraska, Vesna, Jeroncic, Ana, Colonna, Vincenza, Southam, Lorraine, Nyholt, Dale R., Rayner, Nigel William, Perry, John R. B., Toniolo, Daniela, Albrecht, Eva, Ang, Wei, Bandinelli, Stefania, Barbalic, Maja, Barroso, Ines, Beckmann, Jacques S., Biffar, Reiner, Boomsma, Dorret, Campbell, Harry, Corre, Tanguy, Erdmann, Jeanette, Esko, Tonu, Fischer, Krista, Franceschini, Nora, Frayling, Timothy M., Girotto, Giorgia, Gonzalez, Juan R., Harris, Tamara B., Heath, Andrew C., Heid, Iris M., Hoffmann, Wolfgang ... Zeggini, Eleftheria (2012). Genome-wide meta-analysis of common variant differences between men and women. Human Molecular Genetics, 21 (21) dds304, 4805-4815. doi: 10.1093/hmg/dds304
Rye, Marie S., Warrington, Nicole M., Scaman, Elizabeth S. H., Vijayasekaran, Shyan, Coates, Harvey L., Anderson, Denise, Pennell, Craig E., Blackwell, Jenefer M. and Jamieson, Sarra E. (2012). Genome-Wide Association Study to Identify the Genetic Determinants of Otitis Media Susceptibility in Childhood. PLoS One, 7 (10) e48215, e48215.1-e48215.12. doi: 10.1371/journal.pone.0048215
Louise, Sandra, Warrington, Nicole M., McCaskie, Pamela A., Oddy, Wendy H., Zubrick, Stephen R., Hands, Beth, Mori, Trevor A., Briollais, Laurent, Silburn, Sven, Palmer, Lyle J., Mattes, Eugen and Beilin, Lawrence J. (2012). Associations between anxious-depressed symptoms and cardiovascular risk factors in a longitudinal childhood study. Preventive Medicine, 54 (5), 345-350. doi: 10.1016/j.ypmed.2012.03.004
Bradfield, Jonathan P., Taal, H. Rob, Timpson, Nicholas J., Scherag, André, Lecoeur, Cecile, Warrington, Nicole M., Hypponen, Elina, Holst, Claus, Valcarcel, Beatriz, Thiering, Elisabeth, Salem, Rany M., Schumacher, Fredrick R., Cousminer, Diana L., Sleiman, Patrick M. A., Zhao, Jianhua, Berkowitz, Robert I., Vimaleswaran, Karani S., Jarick, Ivonne, Pennell, Craig E., Evans, David M., St Pourcain, Beate, Berry, Diane J., Mook-Kanamori, Dennis O., Hofman, Albert, Rivadeneira, Fernando, Uitterlinden, André G., van Duijn, Cornelia M., van der Valk, Ralf J. P., de Jongste, Johan C. ... Grant, Struan F. A. (2012). A genome-wide association meta-analysis identifies new childhood obesity loci. Nature Genetics, 44 (5), 526-531. doi: 10.1038/ng.2247
Taal, H. Rob, St Pourcain, Beate, Thiering, Elisabeth, Das, Shikta, Mook-Kanamori, Dennis O., Warrington, Nicole M., Kaakinen, Marika, Kreiner-Møller, Eskil, Bradfield, Jonathan P., Freathy, Rachel M., Geller, Frank, Guxens, Mònica, Cousminer, Diana L., Kerkhof, Marjan, Timpson, Nicholas J., Ikram, M. Arfan, Beilin, Lawrence J., Bønnelykke, Klaus, Buxton, Jessica L., Charoen, Pimphen, Chawes, Bo Lund Krogsgaard, Eriksson, Johan, Evans, David M., Hofman, Albert, Kemp, John P., Kim, Cecilia E., Klopp, Norman, Lahti, Jari, Lye, Stephen J. ... Middeldorp, Christel (2012). Common variants at 12q15 and 12q24 are associated with infant head circumference. Nature Genetics, 44 (5), 532-538. doi: 10.1038/ng.2238
Boraska, Vesna, Day-Williams, Aaron, Franklin, Christopher S., Elliott, Katherine S., Panoutsopoulou, Kalliope, Tachmazidou, Ioanna, Albrecht, Eva, Bandinelli, Stefania, Beilin, Lawrence J., Bochud, Murielle, Cadby, Gemma, Ernst, Florian, Evans, David M., Hayward, Caroline, Hicks, Andrew A., Huffman, Jennifer, Huth, Cornelia, James, Alan L., Klopp, Norman, Kolcic, Ivana, Kutalik, Zoltan, Lawlor, Debbie A., Musk, Arthur W., Pehlic, Marina, Pennell, Craig E., Perry, John R. B., Peters, Annette, Polasek, Ozren, St Pourcain, Beate ... Zeggini, Eleftheria (2012). Genome-wide association study to identify common variants associated with brachial circumference: A meta-analysis of 14 cohorts. Plos One, 7 (3) e31369, e31369.1-e31369.10. doi: 10.1371/journal.pone.0031369
Paternoster, Lavinia, Standl, Marie, Chen, Chi-Mei, Ramasamy, Adaikalavan, Bonnelykke, Klaus, Duijts, Liesbeth, Ferreira, Manuel A., Alves, Alexessander C., Thyssen, Jacob P., Albrecht, Eva, Baurecht, Hansjorg, Feenstra, Bjarke, Sleiman, Patrick M. A., Hysi, Piro, Warrington, Nicole M., Curjuric, Ivan, Myhre, Ronny, Curtin, John A., Groen-Blokhuis, Maria M., Kerkhof, Marjan, Saaf, Annika, Franke, Andre, Ellinghaus, David, Folster-Holst, Regina, Dermitzakis, Emmanouil, Montgomery, Stephen B., Prokisch, Holger, Heim, Katharina, Hartikainen, Anna-Lisa ... EArly Genetics Lifecourse Epidemiology (EAGLE) Consortium (2012). Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis. Nature Genetics, 44 (2), 187-192. doi: 10.1038/ng.1017
Middelberg, Rita P., Benyamin, Beben, de Moor, Marleen H. M., Warrington, Nicole M., Gordon, Scott, Henders, Anjali K., Medland, Sarah E., Nyholt, Dale R., de Geus, Eco J. C., Hottenga, Jouke J., Willemsen, Gonneke, Beilin, Lawrence J., Mori, Trevor A., Wright, Margaret J., Heath, Andrew C., Madden, Pamela A. F., Boomsma, Dorret I., Pennell, Craig E., Montgomery, Grant W., Martin, Nicholas G. and Whitfield, John B. (2012). Loci affecting gamma-glutamyl transferase in adults and adolescents show age x SNP interaction and cardiometabolic disease associations. Human Molecular Genetics, 21 (2) ddr478, 446-455. doi: 10.1093/hmg/ddr478
Marsh, J. A., Pennell, C. E., Warrington, N. M., Mook-Kanamori, D., Briollais, L., Lye, S. J., Beilin, L. J., Steegers, E., Hofman, A., Jaddoe, V. W. V., Newnham, J.P. and Palmer, L. J. (2012). Fat mass and obesity-associated obesity-risk genotype is associated with lower foetal growth: An effect that is reversed in the offspring of smoking mothers. Journal of Developmental Origins of Health and Disease, 3 (1), 10-20. doi: 10.1017/S2040174411000638
MacKey, David A., Warrington, Nicole M., Hewitt, Alex W., Oates, Sandra K., Yazar, Seyhan, Soloshenko, Alla, Crawford, Geoffrey J., Mountain, Jenny A. and Pennell, Craig E. (2012). Role of the TCF4 gene intronic variant in normal variation of corneal endothelium. Cornea, 31 (2), 162-166. doi: 10.1097/ICO.0b013e318226155f
Abarin, Taraneh, wu, Yan Yan, Warrington, Nicole, Lye, Stephen, Pennell, Craig and Briollais, Laurent (2012). The impact of breastfeeding on FTO-related BMI growth trajectories: An application to the Raine pregnancy cohort study. International Journal of Epidemiology, 41 (6) dys171, 1650-1660. doi: 10.1093/ije/dys171
Skouen, J. S., Smith, A. J., Warrington, N. M., O'Sullivan, P. B., McKenzie, L., Pennell, C. E. and Straker, L. M. (2012). Genetic variation in the beta-2 adrenergic receptor is associated with chronic musculoskeletal complaints in adolescents. European Journal of Pain (United Kingdom), 16 (9), 1232-1242. doi: 10.1002/j.1532-2149.2012.00131.x
Louise, S., Warrington, N. M., McCaskie, P. A., Oddy, W. H., Zubrick, S. R., Hands, B., Mori, T. A., Briollais, L., Silburn, S., Palmer, L. J., Mattes, E. and Beilin, L. J. (2012). Associations between aggressive behaviour scores and cardiovascular risk factors in childhood. Pediatric Obesity, 7 (4), 319-328. doi: 10.1111/j.2047-6310.2012.00047.x
Webster,Rebecca J., Carter, Kim W., Warrington, Nicole M., Loh, Angeline M., Zaloumis, Sophie, Kuijpers, Taco W., Palmer, Lyle J. and Burgner, David P. (2011). Hospitalisation with infection, asthma and allergy in kawasaki disease patients and their families: Genealogical analysis using linked population data. PLoS One, 6 (11) e28004, e28004.1-e28004.11. doi: 10.1371/journal.pone.0028004
Artigas, M.S., Loth, D.W., Wain, L.V., Gharib, S.A., Obeidat, M., Tang, W.B., Zhai, G.J., Zhao, J.H., Smith, A.V., Huffman, J.E., Albrecht, E., Jackson, C.M., Evans, D.M., Cadby, G., Fornage, M., Manichaikul, A., Lopez, L.M., Johnson, T., Aldrich, M.C., Aspelund, T., Barroso, I., Campbell, H., Cassano, P.A., Couper, D.J., Eiriksdottir, G., Franceschini, N., Garcia, M., Gieger, C., Gislason, G.K. ... GIANT Consortium (2011). Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nature Genetics, 43 (11), 1082-1090. doi: 10.1038/ng.941
Kilpelainen T.O., Den Hoed M., Ong K.K., Grontved A., Brage S., Jameson K., Cooper C., Khaw K.-T., Ekelund U., Wareham N.J., Loos R.J.F., Freathy R.M., Mook-Kanamori D.O., Sovio U., Prokopenko I., Timpson N.J., Berry D.J., Warrington N.M., Widen E., Hottenga J.J., Kaakinen M., Lange L.A., Bradfield J.P., Kerkhof M., Marsh J.A., Magi R., Chen C.-M., Lyon H.N., Kirin M. ... McCarthy M.I. (2011). Obesity-susceptibility loci have a limited influence on birth weight: A meta-analysis of up to 28,219 individuals. American Journal of Clinical Nutrition, 93 (4), 851-860. doi: 10.3945/ajcn.110.000828
Barker, Adam, Sharp, Stephen J., Timpson, Nicholas J., Bouatia-Naji, Nabila, Warrington, Nicole M., Kanoni, Stavroula, Beilin, Lawrence J., Brage, Soren, Deloukas, Panos, Evans, David M., Grontved, Anders, Hassanali, Neelam, Lawlor, Deborah A., Lecoeur, Cecile, Loos, Ruth J.F., Lye, Stephen J., McCarthy, Mark I., Mori, Trevor A., Ndiaye, Ndeye Coumba, Newnham, John P., Ntalla, Ioanna, Pennell, Craig E., St Pourcain, Beate, Prokopenko, Inga, Ring, Susan M., Sattar, Naveed, Visvikis-Siest, Sophie, Dedoussis, George V., Palmer, Lyle J. ... Langenberg, Claudia (2011). Association of genetic loci with glucose levels in childhood and adolescence: A meta-analysis of over 6,000 children. Diabetes, 60 (6), 1805-1812. doi: 10.2337/db10-1575
C Reactive Protein Coronary Heart Disease Genetics Collaboration (CCGC) and Warrington, N. (2011). Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data. BMJ, 342 (7794) d548, d548.1-d548.8. doi: 10.1136/bmj.d548
Sovio, Ulla, Mook-Kanamori, Dennis O., Warrington, Nicole M., Lawrence, Robert, Briollais, Laurent, Palmer, Colin N. A., Cecil, Joanne, Sandling, Johanna K., Syvanen, Ann-Christin, Kaakinen, Marika, Beilin, Lawrie J., Millwood, Iona Y., Bennett, Amanda J., Laitinen, Jaana, Pouta, Anneli, Molitor, John, Smith, George Davey, Ben-Shlomo, Yoav, Jaddoe, Vincent W. V., Palmer, Lyle J., Pennell, Craig E., Cole, Tim J., McCarthy, Mark I., Jarvelin, Marjo-Riitta and Timpson, Nicholas J. (2011). Association between common variation at the FTO locus and changes in body mass index from infancy to late childhood: The complex nature of genetic association through growth and development. PLoS Genetics, 7 (2) e1001307, e1001307.1-e1001307.13. doi: 10.1371/journal.pgen.1001307
Golledge, Jonathan, Biros,Erik, Warrington, Nicole, Jones, Gregory T., Cooper, Matthew, Van Rij, Andre M., Palmer, Lyle J. and Norman, Paul E. (2011). A population-based study of polymorphisms in genes related to sex hormones and abdominal aortic aneurysm. European Journal of Human Genetics, 19 (3), 363-366. doi: 10.1038/ejhg.2010.182
Jamrozik, Euzebiusz F., Warrington, Nicole, McClenaghan, Jane, Hui, Jennie, Musk, Arthur W., James, Alan, Beilby, John P., Hansen, Janice, De Klerk, Nicholas H. and Palmer, Lyle J. (2011). Functional haplotypes in the PTGDR gene fail to associate with asthma in two Australian populations. Respirology, 16 (2), 359-366. doi: 10.1111/j.1440-1843.2010.01917.x
Mook-Kanamori, Dennis O., Marsh, Julie A., Warrington, Nicole M., Taal, H. Rob, Newnham, John P., Beilin, Lawrie J., Lye, Stephen J., Palmer, Lyle J., Hofman, Albert, Steegers, Eric A. P., Pennell, Craig E. and Jaddoe, Vincent W. V. (2011). Variants near CCNL1/LEKR1 and in ADCY5 and fetal growth characteristics in different trimesters. Journal of Clinical Endocrinology and Metabolism, 96 (5), E810-E815. doi: 10.1210/jc.2010-2316
Elks, C. E., Perry, J. R. B., Sulem, P., Chasman, D. I., Franceschini, N., He, C. Y., Lunetta, K. L., Visser, J. A., Byrne, E. M., Cousminer, D. L., Gudbjartsson, D. F., Esko, T., Feenstra, B., Hottenga, J. J., Koller, D. L., Kutalik, Z., Lin, P., Mangino, M., Marongiu, M., McArdle, P. F., Smith, A. V., Stolk, L., Van Wingerden, S. H., Zhao, J. H., Albrecht, E., Corre, T., Ingelsson, E., Hayward, C., Magnusson, P. K. E. ... GIANT Consortium (2010). Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nature Genetics, 42 (12), 1077-1085. doi: 10.1038/ng.714
Webster, Rebecca J., Warrington, Nicole M., Beilby, John P., Frayling, Timothy M. and Palmer, Lyle J. (2010). The longitudinal association of common susceptibility variants for type 2 diabetes and obesity with fasting glucose level and BMI. BMC Medical Genetics, 11 (1) 140. doi: 10.1186/1471-2350-11-140
Warrington, Nicole M., Gianino, Scott M., Jackson, Erin, Goldhoff, Patricia, Garbow, Joel R., Piwnica-Worms, David, Gutmann, David H. and Rubin, Joshua B. (2010). Cyclic AMP suppression is sufficient to induce gliomagenesis in a mouse model of neurofibromatosis-1. Cancer Research, 70 (14), 5717-5727. doi: 10.1158/0008-5472.CAN-09-3769
Burgess, S., Thompson, S. G., Andrews, G., Samani, N. J., Hall, A., Whincup, P., Morris, R., Lawlor, D. A., Davey Smith, G., Timpson, N., Ebrahim, S., Ben-Shlomo, Y., Brown, M., Ricketts, S., Sandhu, M., Reiner, A., Psaty, B., Lange, L., Cushman, M., Hung, J., Thompson, P., Beilby, J., Warrington, N., Palmer, L. J., Nordestgaard, B. G., Tybjaerg-Hansen, A., Zacho, J., Wu, C., Lowe, G. ... Whittaker, J. (2010). Bayesian methods for meta-analysis of causal relationships estimated using genetic instrumental variables. Statistics in Medicine, 29 (12), 1298-1311. doi: 10.1002/sim.3843
Golledge, Jonathan, Biros, Erik, Cooper, Matthew, Warrington, Nicole, Palmer, Lyle J. and Norman, Paul E. (2010). Apolipoprotein E genotype is associated with serum C-reactive protein but not abdominal aortic aneurysm. Atherosclerosis, 209 (2), 487-491. doi: 10.1016/j.atherosclerosis.2009.09.027
Tan, Joo-Huang, Price, Patricia, Gut, Ivo, Stacey, Michael C., Warrington, Nicole M. and Wallace, Hilary J. (2010). Characterization of tumor necrosis factor-α block haplotypes associated with susceptibility to chronic venous leg ulcers in Caucasian patients. Human Immunology, 71 (12), 1214-1219. doi: 10.1016/j.humimm.2010.09.001
Freathy, Rachel M., Mook-Kanamor, Dennis O., Sovio, Ulla, Prokopenko, Inga, Timpson, Nicholas J., Berry, Diane J., Warrington, Nicole M., Widen, Elisabeth, Hottenga, Jouke Jan, Kaakinen, Marika, Lange, Leslie A., Bradfield, Jonathan P., Kerkhof, Marjan, Marsh, Julie A., Magi, Reedik, Chen, Chih-Mei, Lyon, Helen N., Kirin, Mirna, Adair, Linda S., Aulchenko, Yurii S., Bennett, Amanda J., Borja, Judith B., Bouatia-Naji, Nabila, Charoen, Pimphen, Coin, Lachlan ..J. M., Cousminer, Diana L., De Geus, Eco J. C., Deloukas, Panos, Elliott, Paul ... McCarthy, Mark I. (2010). Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight. Nature Genetics, 42 (5), 430-435. doi: 10.1038/ng.567
Ferreira, MAR, Hottenga, JJ, Warrington, NM, Medland, SE, Willemsen, G, Lawrence, RW, Gordon, S, de Geus, EJC, Henders, AK, Smit, JH, Campbell, MJ, Wallace, L, Evans, DM, Wright, MJ, Nyholt, DR, James, AL, Beilby, JP, Penninx, BW, Palmer, LJ, Frazer, IH, Montgomery, GW, Martin, NG and Boomsma, DI (2009). Sequence Variants in Three Loci Influence Monocyte Counts and Erythrocyte Volume. AMERICAN JOURNAL OF HUMAN GENETICS, 85 (5), 745-749. doi: 10.1016/j.ajhg.2009.10.005
Webster, R. J., Warrington, N. M., Weedon, M. N., Hattersley, A. T., McCaskie, P. A., Beilby, J. P., Palmer, L. J. and Frayling, T. M. (2009). The association of common genetic variants in the APOA5, LPL and GCK genes with longitudinal changes in metabolic and cardiovascular traits. Diabetologia, 52 (1), 106-114. doi: 10.1007/s00125-008-1175-9
Daley, Denise, Lemire, Mathieu, Akhabir, Loubna, Chan-Yeung, Moira, He, Jian Qing, McDonald, Treena, Sandford, Andrew, Stefanowicz, Dorota, Tripp, Ben, Zamar, David, Bosse, Yohan, Ferretti, Vincent, Montpetit, Alexandre, Tessier, Marie-Catherine, Becker, Allan, Kozyrskyj, Anita L., Beilby, John, McCaskie, Pamela A., Musk, Bill, Warrington, Nicole, James, Alan, Laprise, Catherine, Palmer, Lyle J., Pare, Peter D. and Hudson, Thomas J. (2009). Analyses of associations with asthma in four asthma population samples from Canada and Australia. Human Genetics, 125 (4), 445-459. doi: 10.1007/s00439-009-0643-8
Gudbjartsson, Daniel F., Bjornsdottir, Unnur S., Halapi, Eve, Helgadottir, Anna, Sulem, Patrick, Jonsdottir, Gudrun M., Thorleifsson, Gudmar, Helgadottir, Hafdis, Steinthorsdottir, Valgerdur, Stefansson, Hreinn, Williams, Carolyn, Hui, Jennie, Beilby, John, Warrington, Nicole M., James, Alan, Palmer, Lyle J., Koppelman, Gerard H., Heinzmann, Andrea, Krueger, Marcus, Boezen, H. Marike, Wheatley, Amanda, Altmuller, Janine, Shin, Hyoung Doo, Uh, Soo-Taek, Cheong, Hyun Sub, Jonsdottir, Brynja, Gislason, David, Park, Choon-Sik, Rasmussen, Linda M. ... Stefansson, Kari (2009). Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction. Nature Genetics, 41 (3), 342-347. doi: 10.1038/ng.323
McClenaghan, J., Warrington, N. M., Jamrozik, E. F., Hui, J., Beilby, J. P., Hansen, J., De Klerk, N. H., James, A. L., Musk, A. W. and Palmer, L. J. (2009). The PHF11 gene is not associated with asthma or asthma phenotypes in two independent populations. Thorax, 64 (7), 620-625. doi: 10.1136/thx.2008.108985
Smallwood, L., Warrington, N., Allcock, R., van Bockxmeer, F., Palmer, L. J., Iacopetta, B., Golledge, J. and Norman, P. E. (2009). Matrix Metalloproteinase-2 Gene Variants and Abdominal Aortic Aneurysm. European Journal of Vascular and Endovascular Surgery, 38 (2), 169-171. doi: 10.1016/j.ejvs.2009.04.019
Lawlor, Debbie A., Harbord, Roger M., Timpson, Nic J., Lowe, Gordon D. O., Rumley, Ann, Gaunt, Tom R., Baker, Ian, Yarnell, John W. G., Kivimäki, Mika, Kumari, Meena, Norman, Paul E., Jamrozik, Konrad, Hankey, Graeme J., Almeida, Osvaldo P., Flicker, Leon, Warrington, Nicole, Marmot, Michael G., Ben-Shlomo, Yoav, Palmer, Lyle J., Day, Ian N. M., Ebrahim, Shah and Smith, George Davey (2008). The association of C-reactive protein and CRP genotype with coronary heart disease: findings from five studies with 4,610 cases amongst 18,637 participants. PLoS One, 3 (8) e3011, e3011.1-e3011.14. doi: 10.1371/journal.pone.0003011
Smallwood, L., Allcock, R., van Bockxmeer, F., Warrington, N., Palmer, L. J., Iacopetta, B. and Norman, P. E. (2008). Polymorphisms of the Interleukin-6 Gene Promoter and Abdominal Aortic Aneurysm. European Journal of Vascular and Endovascular Surgery, 35 (1), 31-36. doi: 10.1016/j.ejvs.2007.08.021
Smallwood, L., Allcock, R., Van Bockxmeer, F., Warrington, N., Palmer, L. J., Iacopetta, B., Golledge, J. and Norman, P. E. (2008). Polymorphisms of the matrix metalloproteinase 9 gene and abdominal aortic aneurysm. British Journal of Surgery, 95 (10), 1239-1244. doi: 10.1002/bjs.6345
Warrington, Nicole M., Woerner, B. Mark, Daginakatte, Girish C., Dasgupta, Biplab, Perry, Arie, Gutmann, David H. and Rubin, Joshua B. (2007). Spatiotemporal differences in CXCL12 expression and cyclic AMP underlie the unique pattern of optic glioma growth in neurofibromatosis type 1. Cancer Research, 67 (18), 8588-8595. doi: 10.1158/0008-5472.CAN-06-2220
Conference Papers
Decina, Caitlin, Warrington, Nicole, Beaumont, Robin, Freathy, Rachel and Evans, David (2024). Examining the association between fetal HLA-C and maternal KIR haplotypes and birthweight in the UK biobank. 56th Annual Conference of the European Society of Human Genetics (ESHG), Glasgow, Scotland, 10-13 June 2023. London, United Kingdom: Nature Publishing Group.
Wang, Geng, Bhatta, Laxmi, Moen, Gunn-Helen, Hwang, Liang-Dar, Kemp, John P., Bond, Tom A., Asvold, Bjorn Olav, Brumpton, Ben, Evans, David M. and Warrington, Nicole M. (2021). Investigating a potential causal relationship between maternal blood pressure during pregnancy and future offspring cardiometabolic health. Behavior Genetics Association 51st Annual Meeting, Online (Zoom), 29 June 2021. New York, United States: Springer.
Moen, Gunn-Helen, Brumpton, Ben, Willer, Cristen, Asvold, Bjorn Olav, Birkeland, Kare, Neale, Michael C., Freathy, Rachel M., Smith, George Davey, Lawlor, Deborah A., Kirkpatrick, Robert M., Warrington, Nicole M. and Evans, David M. (2020). Do maternal intrauterine environmental influences that lower offspring birthweight causally increase offspring cardiometabolic risk factors in later life? A Mendelian randomization study of 45,849 genotyped parent offspring pairs in the HUNT study using the OpenMx software. 50th Annual Meeting of the Behavior-Genetics-Association (BGA), Electr Network, Jun 26, 2020. NEW YORK: SPRINGER.
Evans, David, Warrington, Nicole, Partida, Gabriel Cuellar and Hwang, Daniel (2019). Using Mendelian randomization to estimate the causal effect of maternal (intrauterine) exposures on late onset offspring outcomes. 49th Annual Meeting of the Behavior Genetics Association (BGA), Stockholm, Sweden, 26-29 June, 2019. New York, NY, United States: Springer New York LLC. doi: 10.1007/s10519-019-09973-8
Beaumont, Robin N., Warrington, Nicole M., Horikoshi, Momoko, Day, Felix R., Ong, Ken K., McCarthy, Mark I., Perry, John R. B., Freathy, Rachel M. and Evans, David M. (2018). Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic disease. 27th Annual Meeting of the International-Genetic-Epidemiology-Society (IGES), San Diego, Ca, United States, 14-16 October 2018. Hoboken, NJ, United States: John Wiley & Sons.
Evans, David and Warrington, Nicole (2017). Performing Mendelian randomization using structural equation models. 47th Annual Meeting of the Behavior-Genetics-Association (BGA), Oslo Norway, 28 June - 1 July 2017. New York NY United States: Springer.
Warrington, Nicole M. and Evans, David M. (2016). Locus Discovery in Genome-wide Association Studies using Bivariate Analysis. Annual Meeting of the International-Genetic-Epidemiology-Society, Toronto Canada, Oct 24-26, 2016. HOBOKEN: WILEY-BLACKWELL.
Warrington, Nicole, Hemani, Gibran, Hysi, Pirro, Mangino, Massimo, McMahon, George, Hickey, Martha, Wolke, Dieter, Montgomery, Grant, Pennell, Craig, Spector, Tim, Martin, Nicholas, Medland, Sarah and Evans, David (2016). Genome-wide association study of 6,939 individuals identifies five novel loci and suggests that prenatal exposure to testosterone is not a major determinant of individual differences in 2D:4D finger ratio. 46th Annual Meeting of the Behavior-Genetics-Association, Brisbane Australia, Jun 20-23, 2016. NEW YORK: SPRINGER.
Zheng, Jie, Haycock, Philip, Hemani, Gibran, Elsworth, Benjamin, Shihab, Hashem, Laurin, Charles, Erzurumluoglu, Mesut, Howe, Laurence, Wade, Kaitlin, Warrington, Nicole, Finucane, Hilary, Price, Alkes, Anttila, Verneri, Paternoster, Lavinia, Martin, Richard, Relton, Caroline, Gaunt, Tom, Smith, George Davey, Neale, Benjamin and Evans, David (2016). LD hub and MR-base: online platforms for preforming LD score regression and Mendelian randomization analysis using GWAS summary data. 46th Annual Meeting of the Behavior-Genetics-Association, Brisbane Australia, Jun 20-23, 2016. NEW YORK: SPRINGER.
Waage, J. E., Kreiner-Moller, E., Standl, M., Brix, S., Pers, T. H., Alves, A. C., Warrington, N. M., Tiesler, C. M., Fuertes, E., Franke, L., Hirschhorn, J. N., James, A., Simpson, A., Tung, J. Y., Koppelman, G. H., Postma, D. S., Pennel, C. E., Jarvelin, M-R, Custovic, A., Timpson, N., Ferreira, M. A., Strachan, D. P., Hinds, D., Bisgaard, H. and Bonnelykke, K. (2015). Shared genetic origins of allergy and autoimmune diseases. Congress of the European-Academy-of-Allergy-and-Clinical-Immunology, Barcelona Spain, Jun 06-10, 2015. HOBOKEN: WILEY-BLACKWELL.
Horikoahi, Momoko, Day, Felix R., Perry, John R. B., Hottenga, Jouke-Jan, Li-Gao, Ruifang, Beaumont, Robin, Warrington, Nicole M. and Timpson, Nicholas J. (2015). Large scale genome-wide association study for birth weight identifies 13 novel loci and reveals genetic links with a variety of adult metabolic and anthropometric traits. Annual Meeting of the International-Genetic-Epidemiology-Society (IGES), Baltimore, Md, United States, Oct 04-06 2015. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/gepi.21916
Kemp, John P., Medina-Gomez, Carolina, Warrington, Nicole M., Heppe, Denise H. M., Timpson, Nicholas J., Oei, Ling, St Pourcain, Beate, Kruithof, Claudia J., Zillikens, M. Carola, Hofman, Albert, Uitterlinden, Andre G., Smith, George Davey, Jaddoe, Vincent W. V., Tobias, Jonathan H., Rivadeneira, Fernando and Evans, David M. (2014). Bivariate genetic association analysis of pediatric total-body DXA parameters identifies two novel genetic variants that jointly influence bone mineral content and bone area. Annual Meeting of the American Society for Bone and Mineral Research, Houston, Texas, United States, 12-15 September 2014. Hoboken, NJ, United States: Wiley-Blackwell Publishing.