Dr Angelo Keramidas
Researcher biography
I am interested in ion channels in health and disease. Improved technologies for genetic screening is revealing an expanding catalogue of genetic variants to ion channels that give rise neurological disorders, such as epilespy syndromes, autism spectrum disorder and other neurodevelopmental disorders. My main research focus is on neurotransmitter-activated receptor ion channels that are found at neuronal synapses. These include GABA-A, glycine and glutamate (NMDA) receptors. I also work on other ion channesl such as voltage-gated sodium channels and synaptic receptors expressed in invertebrate nervous systems.
I am an expert at recording single ion channel, synaptic and conventional whole-cell currents for functional and pharmacological analyisis.
I collaborate with biophysicists, molecular biologists, geneticists, electrophysiologists and clinicians that specialise in genetic neurological disorders. I have active projects in collaboration with research groups in Australia, USA and Europe.