Nuclear Magnetic Resonance (NMR) Spectroscopy Facility
600 MHz and 500MHz spectrometers
Our 600MHz is equipped with a cryoprobe, which allows the electronics of the system to be cooled to very low temperatures (less than -250 °C) to reduce electronic noise that may otherwise limit the detection of smaller signals.
Samples can either be run more quickly, which benefits researchers who generate large volumes of samples, or smaller sample quantities can be studied, which otherwise might be ‘invisible’. Both the 600 and 500 MHz spectrometers are equipped with automatic sample changers.
This robotic equipment enables a variety of biodiscovery and screening applications that may require higher capacity, faster output and time efficiency.
| Item | Bruker Avance HDX III 600 MHz | Bruker Avance III HD 500 MHz |
|---|---|---|
| Probe | 5mm TCI (H(F)CN) with z-gradient | 5mm TXI (HCN) with z-gradient |
| Software | Windows 7 Topspin 3.5 | Windows 7 Topspin 3.5 |
| Sample Changer | SampleCase-60 | BACS-60 |
900 MHz spectrometer
Belonging to the Queensland NMR Network (managed and maintained by UQ’s Centre for Advanced Imaging), the 900 MHz spectrometer is equipped with a cryoprobe and sample changer, making it the most powerful state-of-the-art NMR spectrometer in Australia.
It boasts a magnetic field in excess of 600,000 times that of the Earth’s magnetic field. An analysis that might take days on a smaller NMR takes just a single day, speeding up the rate of discovery. Such high field superconducting magnets also have greatly improved sensitivity and resolution and thus enable researchers to explore the structure and dynamics of much larger proteins.
The NMR facility is available to internal and external researchers on a user-pays basis. With training you may conduct your own experiments, or we can process samples for you. Additionally, our highly-trained staff can assist with interpretation and analysis of results.