Dr Kathrin Eschke
Postdoctoral Research Fellow
Institute for Molecular Bioscience
+61 7 344 36176
Journal Articles
Emanuel, Jackson, Papies, Jan, Galander, Celine, Adler, Julia M, Heinemann, Nicolas, Eschke, Kathrin, Merz, Sophie, Pischon, Hannah, Rose, Ruben, Krumbholz, Andi, Kulić, Žarko, Lehner, Martin D, Trimpert, Jakob and Müller, Marcel A (2023). In vitro and in vivo effects of Pelargonium sidoides DC. root extract EPs® 7630 and selected constituents against SARS-CoV-2 B.1, Delta AY.4/AY.117 and Omicron BA.2. Frontiers in Pharmacology, 14 1214351, 1-17. doi: 10.3389/fphar.2023.1214351
Labzin, Larisa I., Chew, Keng Yih, Eschke, Kathrin, Wang, Xiaohui, Esposito, Tyron, Stocks, Claudia J., Rae, James, Patrick, Ralph, Mostafavi, Helen, Hill, Brittany, Yordanov, Teodor E., Holley, Caroline L., Emming, Stefan, Fritzlar, Svenja, Mordant, Francesca L., Steinfort, Daniel P., Subbarao, Kanta, Nefzger, Christian M., Lagendijk, Anne K., Gordon, Emma J., Parton, Robert G., Short, Kirsty R., Londrigan, Sarah L. and Schroder, Kate (2023). Macrophage ACE2 is necessary for SARS-CoV-2 replication and subsequent cytokine responses that restrict continued virion release. Science Signaling, 16 (782) eabq1366, eabq1366. doi: 10.1126/scisignal.abq1366
Kreye, Jakob, Reincke, S. Momsen, Edelburg, Stefan, Jeworowski, Lara M., Kornau, Hans-Christian, Trimpert, Jakob, Hombach, Peter, Halbe, Sophia, Noelle, Volker, Meyer, Martin, Kattenbach, Stefanie, Sanchez-Sendin, Elisa, Schmidt, Marie L., Schwarz, Tatjana, Rose, Ruben, Krumbholz, Andi, Merz, Sophie, Adler, Julia M., Eschke, Kathrin, Abdelgawad, Azza, Schmitz, Dietmar, Sander, Leif E., Janssen, Uwe, Corman, Victor M. and Pruess, Harald (2023). Preclinical safety and efficacy of a therapeutic antibody that targets SARS-CoV-2 at the sotrovimab face but is escaped by Omicron. iScience, 26 (4) 106323, 1-22. doi: 10.1016/j.isci.2023.106323
Rothenberger, Sylvia, Hurdiss, Daniel L., Walser, Marcel, Malvezzi, Francesca, Mayor, Jennifer, Ryter, Sarah, Moreno, Hector, Liechti, Nicole, Bosshart, Andreas, Iss, Chloe, Calabro, Valerie, Cornelius, Andreas, Hospodarsch, Tanja, Neculcea, Alexandra, Looser, Thamar, Schlegel, Anja, Fontaine, Simon, Villemagne, Denis, Paladino, Maria, Schiegg, Dieter, Mangold, Susanne, Reichen, Christian, Radom, Filip, Kaufmann, Yvonne, Schaible, Doris, Schlegel, Iris, Zitt, Christof, Sigrist, Gabriel, Straumann, Marcel ... Trimpert, Jakob (2022). The trispecific DARPin ensovibep inhibits diverse SARS-CoV-2 variants. Nature Biotechnology, 40 (12), 1845-1854 . doi: 10.1038/s41587-022-01382-3
Los, Bruna, Preussner, Marco, Eschke, Kathrin, Vidal, Ricardo Martin, Abdelgawad, Azza, Olofsson, Didrik, Keiper, Sandra, Paulo-Pedro, Margarida, Grindel, Alica, Meinke, Stefan, Trimpert, Jakob and Heyd, Florian (2022). Body temperature variation controls pre-mRNA processing and transcription of antiviral genes and SARS-CoV-2 replication. Nucleic Acids Research, 50 (12), 6769-6785. doi: 10.1093/nar/gkac513
Wyler, Emanuel, Adler, Julia M., Eschke, Kathrin, Teixeira Alves, G., Peidli, Stefan, Pott, Fabian, Kazmierski, Julia, Michalick, Laura, Kershaw, Olivia, Bushe, Judith, Andreotti, Sandro, Pennitz, Peter, Abdelgawad, Azza, Postmus, Dylan, Goffinet, Christine, Kreye, Jakob, Reincke, S. Momsen, Prüss, Harald, Blüthgen, Nils, Gruber, Achim D., Kuebler, Wolfgang M., Witzenrath, Martin, Landthaler, Markus, Nouailles, Geraldine and Trimpert, Jakob (2022). Key benefits of dexamethasone and antibody treatment in COVID-19 hamster models revealed by single-cell transcriptomics. Molecular Therapy, 30 (5), 1952-1965. doi: 10.1016/j.ymthe.2022.03.014
Chaudhry, M. Zeeshan, Eschke, Kathrin, Hoffmann, Markus, Grashoff, Martina, Abassi, Leila, Kim, Yeonsu, Brunotte, Linda, Ludwig, Stephan, Kröger, Andrea, Klawonn, Frank, Pöhlmann, Stefan H. and Cicin-Sain, Luka (2022). Rapid SARS-CoV-2 adaptation to available cellular proteases. Journal of Virology, 96 (5) e0218621, 1-17. doi: 10.1128/jvi.02186-21
Kim, Yeonsu, Zheng, Xiaoyan, Eschke, Kathrin, Chaudhry, M. Zeeshan, Bertoglio, Federico, Tomić, Adriana, Krmpotić, Astrid, Hoffmann, Markus, Bar-On, Yotam, Boehme, Julia, Bruder, Dunja, Ebensen, Thomas, Brunotte, Linda, Ludwig, Stephan, Messerle, Martin, Guzman, Carlos, Mandelboim, Ofer, Hust, Michael, Pöhlmann, Stefan, Jonjić, Stipan and Čičin-Šain, Luka (2022). MCMV-based vaccine vectors expressing full-length viral proteins provide long-term humoral immune protection upon a single-shot vaccination. Cellular and Molecular Immunology, 19 (2), 234-244. doi: 10.1038/s41423-021-00814-5
Trimpert, Jakob, Adler, Julia M, Eschke, Kathrin, Abdelgawad, Azza, Firsching, Theresa C, Ebert, Nadine, Thao, Tran Thi Nhu, Gruber, Achim D, Thiel, Volker, Osterrieder, Nikolaus and Kunec, Dusan (2021). Live attenuated virus vaccine protects against SARS-CoV-2 variants of concern B.1.1.7 (Alpha) and B.1.351 (Beta). Science Advances, 7 (49) eabk0172, eabk0172. doi: 10.1126/sciadv.abk0172
Pommerenke, Claudia, Rand, Ulfert, Uphoff, Cord C., Nagel, Stefan, Zaborski, Margarete, Hauer, Vivien, Kaufmann, Maren, Meyer, Corinna, Denkmann, Sabine A., Riese, Peggy, Eschke, Kathrin, Kim, Yeonsu, Safranko, Zeljka Macak, Kurolt, Ivan-Christian, Markotic, Alemka, Cicin-Sain, Luka and Steenpass, Laura (2021). Identification of cell lines CL-14, CL-40 and CAL-51 as suitable models for SARS-CoV-2 infection studies. PloS one, 16 (8) e0255622, e0255622. doi: 10.1371/journal.pone.0255622
Bertoglio, Federico, Fühner, Viola, Ruschig, Maximilian, Heine, Philip Alexander, Abassi, Leila, Klünemann, Thomas, Rand, Ulfert, Meier, Doris, Langreder, Nora, Steinke, Stephan, Ballmann, Rico, Schneider, Kai-Thomas, Roth, Kristian Daniel Ralph, Kuhn, Philipp, Riese, Peggy, Schäckermann, Dorina, Korn, Janin, Koch, Allan, Chaudhry, M Zeeshan, Eschke, Kathrin, Kim, Yeonsu, Zock-Emmenthal, Susanne, Becker, Marlies, Scholz, Margitta, Moreira, Gustavo Marçal Schmidt Garcia, Wenzel, Esther Veronika, Russo, Giulio, Garritsen, Hendrikus S P, Casu, Sebastian ... Hust, Michael (2021). A SARS-CoV-2 neutralizing antibody selected from COVID-19 patients binds to the ACE2-RBD interface and is tolerant to most known RBD mutations. Cell Reports, 36 (4) 109433, 1-23. doi: 10.1016/j.celrep.2021.109433
Pavulraj, Selvaraj, Eschke, Kathrin, Theisen, Jana, Westhoff, Stephanie, Reimers, Gitta, Andreotti, Sandro, Osterrieder, Nikolaus and Azab, Walid (2021). Equine herpesvirus type 4 (EHV-4) outbreak in Germany: virological, serological, and molecular investigations. Pathogens, 10 (7), 810. doi: 10.3390/pathogens10070810
Bertoglio, Federico, Meier, Doris, Langreder, Nora, Steinke, Stephan, Rand, Ulfert, Simonelli, Luca, Heine, Philip Alexander, Ballmann, Rico, Schneider, Kai-Thomas, Roth, Kristian Daniel Ralph, Ruschig, Maximilian, Riese, Peggy, Eschke, Kathrin, Kim, Yeonsu, Schäckermann, Dorina, Pedotti, Mattia, Kuhn, Philipp, Zock-Emmenthal, Susanne, Wöhrle, Johannes, Kilb, Normann, Herz, Tobias, Becker, Marlies, Grasshoff, Martina, Wenzel, Esther Veronika, Russo, Giulio, Kröger, Andrea, Brunotte, Linda, Ludwig, Stephan, Fühner, Viola ... Hust, Michael (2021). SARS-CoV-2 neutralizing human recombinant antibodies selected from pre-pandemic healthy donors binding at RBD-ACE2 interface. Nature Communications, 12 (1) 1577. doi: 10.1038/s41467-021-21609-2
Soilemetzidou, Eirini S., de Bruin, Erwin, Eschke, Kathrin, Azab, Walid, Osterrieder, Nikolaus, Czirjak, Gabor A., Buuveibaatar, Bayarbaatar, Kaczensky, Petra, Koopmans, Marion, Walzer, Chris and Greenwood, Alex D. (2020). Bearing the brunt: Mongolian khulan (Equus hemionus hemionus) are exposed to multiple influenza A strains. Veterinary Microbiology, 242 108605. doi: 10.1016/j.vetmic.2020.108605
Trimpert, Jakob, Groenke, Nicole, Kunec, Dusan, Eschke, Kathrin, He, Shulin, McMahon, Dino P. and Osterrieder, Nikolaus (2019). A proofreading-impaired herpesvirus generates populations with quasispecies-like structure. Nature Microbiology, 4 (12), 2175-2183. doi: 10.1038/s41564-019-0547-x
Trimpert, Jakob, Groenke, Nicole, Kunec, Dusan, Eschke, Kathrin, He, Shulin, McMahon, Dino P. and Osterrieder, Nikolaus (2019). A proofreading-impaired herpesvirus generates populations with quasispecies-like structure (vol 4, pg 2025, 2019). Nature Microbiology, 4 (11), 2025-2025. doi: 10.1038/s41564-019-0598-z
Pavulraj, Selvaraj, Eschke, Kathrin, Prahl, Adriane, Flügger, Michael, Trimpert, Jakob, van den Doel, Petra B., Andreotti, Sandro, Kaessmeyer, Sabine, Osterrieder, Nikolaus and Azab, Walid (2019). Fatal elephant endotheliotropic herpesvirus infection of two young Asian elephants. Microorganisms, 7 (10), 396. doi: 10.3390/microorganisms7100396
Azab, Walid, Bedair, Sameh, Abdelgawad, Azza, Eschke, Kathrin, Farag, Gemelat K., Abdel-Raheim, Ali, Greenwood, Alex D., Osterrieder, Nikolaus and Ali, Ahmed A. H. (2019). Detection of equid herpesviruses among different Arabian horse populations in Egypt. Veterinary Medicine and Science, 5 (3), 361-371. doi: 10.1002/vms3.176
Eschke, Kathrin, Trimpert, Jakob, Osterrieder, Nikolaus and Kunec, Dusan (2018). Attenuation of a very virulent Marek's disease herpesvirus (MDV) by codon pair bias deoptimization. PLoS Pathogens, 14 (1), e1006857. doi: 10.1371/journal.ppat.1006857
Gelhaus, Sandra, Thaa, Bastian, Eschke, Kathrin, Veit, Michael and Schwegmann-Weßels, Christel (2014). Palmitoylation of the Alphacoronavirus TGEV spike protein S is essential for incorporation into virus-like particles but dispensable for S-M interaction. Virology, 464-465, 397-405. doi: 10.1016/j.virol.2014.07.035
Conference Paper
Akison, Mia C., Eschke, Kathrin, Monteith, Gregory, Roberts-Thomson, Sarah, Labzin, Larisa and Robitaille, Mélanie (2023). Gene expression of calcium signalling modulators in SARS-CoV-2 infection. ASCEPT Annual Scientific, Sydney, NSW, Australia, 20-23 November 2023.