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Yap Group
Group Leader
Professor Alpha Yap
Professor and ARC Laureate FellowInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Researcher biography:My group studies the role of cadherin cell adhesion molecules in morphogenesis and tumor development. E-cadherin is a key mediator of cell-cell recognition. It participates in tissue patterning and its dysfunction contributes to tumor progression and invasion.
Associate Professor Yap is the group leader for Cadherin cell adhesion molecules, Epithelial morphogenesis & Cell locomotion research at the IMB.
Body:Highlights
Professor Alpha Yap is a cell biologist. After training in Internal Medicine, Endocrinology and Cell Physiology, he undertook postdoctoral research with Barry Gumbiner at Memorial Sloan-Kettering Cancer Center (New York) before returning to Australia to establish his independent research group.
His research is at the leading edge of a rapidly developing field of science called mechanobiology. Mechanobiology explores how mechanical forces influence biology. Professor Yap is particularly interested in understanding how cells communicate by exerting force upon one another.
Collaborating across disciplines with colleagues from physics, developmental biology and mathematics, his research group has been instrumental in discovering how mechanical forces are generated, and sensed, to coordinate cell behaviour in tissues. Focusing on the epithelial tissues that are the major barriers of the body, Professor Yap believes that their cells monitor force to detect changes in the health of the tissue. This has important implications for understanding diseases such as cancer and inflammation.
Professor Yap currently serves on the editorial boards of several major international journals, amongst them Developmental Cell, Current Biology and Molecular Biology of the Cell.
He was the recipient of the 2013 President’s Medal of the Australia and New Zealand Society for Cell and Developmental Biology and is a Principal Research Fellow of the National Health and Medical Research Council of Australia.
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Researchers
Dr Ellen Potoczky
Postdoctoral Research FellowInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Dr Julia Eckert
Visiting AcademicInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:Dr Sarah Sale
Postdoctoral Research FellowInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Dr Fabienne Haslam
Postdoctoral Research FellowInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Students
Miss Denni Currin-Ross
PhD student & Research OfficerInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Ms Zoya Mann
PhD student & Research OfficerInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Ms Le Thanh Huyen Nguyen
PhD StudentInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Ms Angela Khin Oo Lwin
PhD StudentInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Mr Akshar Rao
PhD StudentInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Walker Group
Group Leader
Professor Mark Walker
Professorial Research Fellow & Group LeaderInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Body:Lab Manager
Dr Amanda Walker
Senior Research AssistantInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:Project Manager
Mr Miguel Aguirre
Project ManagerInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:Postdoctoral Researchers
Dr Stephan Brouwer
Research FellowInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Researcher biography:Stephan Brouwer (ORCiD: 0000-0002-9777-2992) is a postdoctoral research fellow at the University of Queensland. With expertise in bacterial pathogenesis, encompassing both Gram-negative and Gram-positive human pathogens, his research explores the interaction between infectious disease agents and the human host. Much of his work focuses on understanding and preventing disease caused by the human pathogen Group A Streptococcus (GAS; Streptococcus pyogenes). He is at the forefront of the global effort to characterise a scarlet fever outbreak which began in North Asia in 2011, and his current research themes centre around the emergence of new hypervirulent GAS lineages that pose a major public health threat. Stephan utilises modern molecular technologies to study host-pathogen interactions and identify the genetic requirements for GAS to cause disease, with the aim to pursue the development of life-saving therapeutic and preventative advances. He has published his findings in Top Tier journals and helped to establish a sentinel hospital surveillance system in Australia to monitor the importation of GAS isolates causing epidemic scarlet fever.
Stephan completed his PhD in 2015 at one of Germany's most respected research institutes, Helmholtz Centre for Infection Research (HZI), where he conducted research on post-transcriptional regulatory mechanisms in the human pathogen Pseudomonas aeruginosa. He then moved to Australia to join the group of Prof. Mark Walker at the Institute for Molecular Bioscience, University of Queensland, where he is working eversince.
Dr Nichaela Harbison-Price
Postdoctoral Research Fellow & Postdoctoral Research FellowInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Dr David De Oliveira
Research FellowInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Dr Johanna Richter
Postdoctoral Research Fellow/Research OfficerInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Dr Steven Hancock
Postdoctoral Research FellowInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Dr Katelyn Richards
Postdoctoral Research FellowInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Dr Rochelle Da Costa
Postdoctoral Research FellowInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Dr Jack Na
Researcher profile is public:1Supervisor:Research Assistants
Ms Laura Davis
Senior Research AssistantInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:Mr Hayden Whyte
Senior Research AssistantInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:Dr Gayathiri Elangovan
Research/Laboratory AssistantInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Dr Cindy Tay
Research AssistantInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:Mr Jack O'Donohue
Research AssistantInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:PhD Students
Ms Ruby Heaton
PhD studentInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Ms Olivia Bertolla
PhD StudentInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:Ms Phoebe Shaw
PhD StudentInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:Mr Brody Pullinger
PhD StudentInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:Miss Jasmine Wells
PhD StudentInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:- Higher degree by research (PhD) studentInstitute for Molecular Bioscience
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The Edge: Genetics
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