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- Sepsis occurs when the body’s immune response to infection damages its own tissues. In severe cases, multiple organ failure can occur. If not treated promptly, the patient will die. Yet, we currently don't have reliable treatments for it. Our solution is to target the immune system itself. My PhD focuses on a machine in our cells that is important for recognising bacterial infection and recruiting immune responders. My goal is to discover how we can switch this machine on and off.
- Internal Communications and Senior Executive AssistantInstitute for Molecular Bioscience
- Human Resources AdvisorInstitute for Molecular Bioscience
- Higher degree by research (PhD) studentInstitute for Molecular Bioscience
- Masters StudentInstitute for Molecular Bioscience
- Chief Operating OfficerARC Centre of Excellence for Innovations in Peptide and Protein ScienceDeputy DirectorInstitute for Molecular Bioscience
Nefzger group
Group Leader
Dr Christian Nefzger
Senior Research Fellow - GLInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Researcher biography:Kindly visit my laboratory's webpage for more information
Research Members
Dr Xiaoli Chen
Supervisor, Laboratory/ies & Research AssistantInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:Dr Marina Naval Sanchez
NHMRC Emerging Leadership FellowInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Researcher biography:Dr. Marina Naval-Sanchez is a NHMRC Research Fellow at the Institute for Molecular Bioscience at The University of Queensland (Australia). She pursued postdoctoral studies in 2019-2024 in the Institute for Molecular Bioscience, The University of Queensland (Australia) and as an Office Chief Executive (OCE) Fellow in 2015-2019 at the Commonwealth Scientific and Industrial Research Organisation (CSIRO) (Australia). She received her PhD in Molecular Biosciences in 2014 from KULeuven (Belgium). She received her MSc in Applied Bioinformatics in 2009 from Cranfield University (UK) and MSc in Agriculture Engineering in 2008 from the Universitat de Lleida (Spain).
Marina's research program applies state-of-the-art bioinformatic, machine learning, and genetic and genomic tools to unearth the master regulators and enhancer grammar governing development and ageing across species (mouse and human) and to decipher the genomic (regulatory) impact of evolution, domestication and human selection in farm species (sheep, cattle, salmon). Her research outcomes have been published in high-impact journals such as Cell Metabolism, Nature Communications, Genome Biology, Nucleic Acids Research, Genome Research and Molecular Biology and Evolution.
Her research efforts have been supported by domestic and international fellowships and grants, including the Australian National Health and Medical Research Council (NHMRC, EL1 2024 Recipient), Advance Queensland, UQ Innovation Connections, CSIRO Scientific Investment Projects, CSIRO OCE Fellowships, and Flanders Wetesnchappelijk Onderzoek (FWO) PhD Fellowship.
Ying Yang
PhD StudentInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Jingyu Zhang
Masters StudentInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Monisha Ganesan
Masters StudentInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Sharda Kolekar
Research AssistantInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Yifei Huang
Masters StudentInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Dr Ralph Patrick
Postdoctoral Research FellowInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Researcher biography:Ralph Patrick is a researcher focussed on understanding the molecular drivers of ageing and age-associated diseases and developing new therapeutic approaches to help alleviate diseases of ageing. He is trained as a computational biologist, with a BSc (Hons) and PhD from the University of Queensland (UQ). After completion of his PhD in 2016, he worked as a postdoctoral scientist at the Victor Chang Cardiac Research Institute (VCCRI) in Sydney for nearly six years. At the VCCRI, a major focus of his research was mapping out how the individual cells of the heart respond to a heart attack at the gene expression level and how these compare to other forms of chronic heart disease. Following the VCCRI, he joined the Ageing and Cellular Reprogramming lab at the IMB in 2022 as a postdoctoral fellow. His work at the IMB focusses on understanding the epigenetic and transcription factor drivers of the ageing process and leveraging this knowledge to develop new strategies for restoring youthful cell states. Any potential collaborators or students interested in this research area are welcome to contact him.
Mr Mohammadhosein Esmaeili
Researcher profile is public:0Supervisor:
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The Edge: Genetics
People have known for thousands of years that parents pass traits to their children, but it is only relatively recently that our technology has caught up to our curiosity, enabling us to delve into the mystery of how this inheritance occurs, and the implications for predicting, preventing and treating disease.
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