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- PhD StudentInstitute for Molecular Bioscience
Lagendijk team
Group leader
Associate Professor Anne Lagendijk
Senior Principal Research Fellow - GLInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Body:Highlights
Dr Anne Lagendijk's research focusses on the development and maintenance of a functional blood vessel network. These cells that make up the vessels continuously adapt their size, adhesiveness and compliance order to ensure the right balance between vessel integrity and permeability in a context dependent manner. Mechanical cues play a major role in the functional adaptation of blood vessels. Despite ongoing research unraveling the structural components of mechanical hubs in the cells, it is essential to assess the magnitude of forces that are transduced at these sites and the biological consequences for vessel function. She has previously developed a VE-cadherin tension biosensor line in zebrafish. This line provides the first vertebrate model that reports intra-molecular tension. Dr Lagendijk utilised this tool to identify changes in junctional organisation and VE-cadherin tension that occur as arteries mature and revealed molecular pathways that allow for this maturation to happen.
In addition, she has developed new disease models that are allowing her to probe the initiating mechanisms of vascular malformations that lead to neurological deficits and stroke with unprecedented cellular and subcellular resolution. Dr Lagendijk is currently continuing on from her previous work by investigating how forces and mechanically induced pathways at distinct mechanically active sites in the cell contribute to building and maintaining a healthy vasculature.
Researchers
Mr Ryan Brown
Research OfficerInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Miss Taniya Dewathapedige
Research AssistantInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:Mr Alexander Yu
Casual Senior Research OfficerInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:Students
Miss Mikaela Keyser
PhD studentInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:Miss Kahli Jones
PhD studentInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:Ms Amber Driessen
PhD StudentInstitute for Molecular BioscienceResearcher profile is public:0Supervisor:Ms Patricia Essebier
PhD StudentInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Ms Hana Gomibuchi
StudentInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:Ms Joey Tay
StudentInstitute for Molecular BioscienceResearcher profile is public:1Supervisor:- Higher degree by research (PhD) studentInstitute for Molecular Bioscience
- 20 Mar 2025Professor Glenn did his PhD at the University of Sydney before postdoctoral studies at the University of Oxford. After academic stints at the University of Sydney and the University of Connecticut Health Center, he joined the Institute for Molecular Bioscience in 2007. Glenn is a leader in the field of venoms-based drug and insecticide discovery. Glenn’s laboratory maintains one of the largest venom collections in the world, sourced from more than 500 species of venomous invertebrates. In 2023 Glenn received the Prime Minister’s Prize for Innovation for his translational work, and he was elected a Fellow of the Australian Academy of Science in 2024.
- Visiting ResearcherInstitute for Molecular Bioscience
- Postdoctoral Research FellowInstitute for Molecular Bioscience
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