Mass Spectrometry Facility

IMB’s Mass Spectrometry Facility is home to a suite of state-of-the-art mass spectrometry, high-performance liquid chromatography, and robotic instrumentation, that has been refined and optimised to investigate biological systems in a high-throughput qualitative and quantitative manner.

The facility enables researchers at IMB to investigate a broad range of mass spectrometric applications, including molecular discovery, identification, characterisation and quantification. They are gaining insights into protein interactions and structures, amino acid sequence, post-translational modifications, compound stability, and bioavailability of potential therapeutics in a range of biological systems.

Some of the recent discoveries made using the facility include the identification and characterisation of potential therapeutic molecules from natural product extracts using de-novo peptide sequencing, and revealing the quantitative bioavailability characteristics of new molecules in the discovery and development of potential therapeutic molecules for a number of diseases including chronic pain, breast and ovarian cancer, and chronic kidney disease.

Equipment available

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