Mr Alun Jones
Mass Spectrometry Facility Manager
Institute for Molecular Bioscience
+61 7 334 62996
Alun has more than 28 years of experience in biological mass spectrometry in both academia and industry in the UK, Canada and USA. During this time, he has developed HPLC-mass spectrometry interfaces, methods of analysis for natural products, drug and pesticide analysis, peptide and protein analysis.
Book Chapters
Colgrave, Michelle L., Allingham, Peter G., Tyrrell, Kerri and Jones, Alun (2019). Multiple reaction monitoring for the accurate quantification of amino acids: using hydroxyproline to estimate collagen content. Amino acid analysis: methods and protocols. (pp. 33-45) New York, NY United States: Humana Press. doi: 10.1007/978-1-4939-9639-1_4
Inserra, Marco, Lavrukhina, Yelena, Jones, Alun, Lewis, Richard J. and Vetter, Irina (2017). Ciguatoxin detection methods and high-throughput assays. Analysis of food toxins and toxicants. (pp. 469-487) edited by Yiu-Chung Wong and Richard J. Lewis. Oxford, United Kingdom: Wiley Blackwell. doi: 10.1002/9781118992685.ch15
Colgrave, Michelle L., Allingham, Peter G., Tyrrell, Kerri and Jones, Alun (2012). Multiple reaction monitoring for the accurate quantification of amino acids: using hydroxyproline to estimate collagen content. Amino acid analysis: methods and protocols. (pp. 291-303) edited by Michail A. Alterman and Peter Hunziker. New York, United States: Humana Press. doi: 10.1007/978-1-61779-445-2_23
Journal Articles
Fernandez-Rojo, Manuel A., Pearen, Michael A., Burgess, Anita G., Ikonomopoulou, Maria P., Hoang-Le, Diem, Genz, Berit, Saggiomo, Silvia L., Nawaratna, Sujeevi S. K., Poli, Maura, Reissmann, Regina, Gobert, Geoffrey N., Deutsch, Urban, Engelhardt, Britta, Brooks, Andrew J., Jones, Alun, Arosio, Paolo and Ramm, Grant A. (2024). The heavy subunit of ferritin stimulates NLRP3 inflammasomes in hepatic stellate cells through ICAM-1 to drive hepatic inflammation. Science Signaling, 17 (830) eade4335, 1-16. doi: 10.1126/scisignal.ade4335
Wu, Zhixuan, Shen, Sophie, Mizikovsky, Dalia, Cao, Yuanzhao, Naval-Sanchez, Marina, Tan, Siew Zhuan, Alvarez, Yanina D., Sun, Yuliangzi, Chen, Xiaoli, Zhao, Qiongyi, Kim, Daniel, Yang, Pengyi, Hill, Timothy A., Jones, Alun, Fairlie, David P., Pébay, Alice, Hewitt, Alex W., Tam, Patrick P.L., White, Melanie D., Nefzger, Christian M. and Palpant, Nathan J. (2024). Wnt dose escalation during the exit from pluripotency identifies tranilast as a regulator of cardiac mesoderm. Developmental Cell, 59 (6), 705-722.e8. doi: 10.1016/j.devcel.2024.01.019
Zhou, Yan, Harvey, Peta J., Koehbach, Johannes, Chan, Lai Yue, Jones, Alun, Andersson, Åsa, Vetter, Irina, Durek, Thomas and Craik, David J. (2023). A chemoenzymatic approach to produce a cyclic analogue of the analgesic drug MVIIA (Ziconotide). Angewandte Chemie, 135 (29) e202302812, 1-5. doi: 10.1002/ange.202302812
Curson, James E. B., Liu, Liping, Luo, Lin, Muusse, Timothy W., Lucas, Richard M., Gunther, Kimberley S., Vajjhala, Parimala R., Abrol, Rishika, Jones, Alun, Kapetanovic, Ronan, Stacey, Katryn J., Stow, Jennifer L. and Sweet, Matthew J. (2023). TLR4 phosphorylation at tyrosine 672 activates the ERK/c‐FOS signaling module for LPS‐induced cytokine responses in macrophages. European Journal of Immunology, 53 (7) e2250056, e2250056. doi: 10.1002/eji.202250056
Zhou, Yan, Harvey, Peta J., Koehbach, Johannes, Chan, Lai Yue, Jones, Alun, Andersson, Åsa, Vetter, Irina, Durek, Thomas and Craik, David J. (2023). A chemo-enzymatic approach to produce a cyclic analogue of the analgesic drug MVIIA (Ziconotide). Angewandte Chemie, 62 (29) e202302812, e202302812. doi: 10.1002/anie.202302812
Kojic, Marija, Abbassi, Nour E. H., Lin, Ting-Yu, Jones, Alun, Wakeling, Emma L., Clement, Emma, Nakou, Vasiliki, Singleton, Matthew, Dobosz, Dominika, Kaliakatsos, Marios, Glatt, Sebastian and Wainwright, Brandon J. (2023). A novel ELP1 mutation impairs the function of the Elongator complex and causes a severe neurodevelopmental phenotype. Journal of Human Genetics, 68 (7), 445-453. doi: 10.1038/s10038-023-01135-3
Kong, Dehui, Saqer, Alaa A., Carpinelli de Jesus, Matheus, Khan, Nemat, Jones, Alun, Blanchfield, Joanne T., Smith, Maree T. and Williams, Craig M. (2022). Design, synthesis and evaluation of alpha lipoic acid derivatives to treat multiple sclerosis-associated central neuropathic pain. Bioorganic and Medicinal Chemistry, 69 116889, 1-10. doi: 10.1016/j.bmc.2022.116889
Gaik, Monika, Kojic, Marija, Stegeman, Megan R., Öncü‐Öner, Tülay, Kościelniak, Anna, Jones, Alun, Mohamed, Ahmed, Chau, Pak Yan Stefanie, Sharmin, Sazia, Chramiec‐Głąbik, Andrzej, Indyka, Paulina, Rawski, Michał, Biela, Anna, Dobosz, Dominika, Millar, Amanda, Chau, Vann, Ünalp, Aycan, Piper, Michael, Bellingham, Mark C., Eichler, Evan E., Nickerson, Deborah A., Güleryüz, Handan, Abbassi, Nour El Hana, Jazgar, Konrad, Davis, Melissa J., Mercimek‐Andrews, Saadet, Cingöz, Sultan, Wainwright, Brandon J. and Glatt, Sebastian (2022). Functional divergence of the two Elongator subcomplexes during neurodevelopment. EMBO Molecular Medicine, 14 (7) e15608, e15608. doi: 10.15252/emmm.202115608
Hering, Anke, Jieu, Beverly, Jones, Alun and Muttenthaler, Markus (2022). Approaches to improve the quantitation of oxytocin in human serum by mass spectrometry. Frontiers in Chemistry, 10 889154, 1-11. doi: 10.3389/fchem.2022.889154
Wu, Yue, Cui, Zhenling, Huang, Yen-Hua, de Veer, Simon J., Aralov, Andrey V., Guo, Zhong, Moradi, Shayli V., Hinton, Alexandra O., Deuis, Jennifer R., Guo, Shaodong, Chen, Kai-En, Collins, Brett M., Vetter, Irina, Herzig, Volker, Jones, Alun, Cooper, Matthew A., King, Glenn F., Craik, David J., Alexandrov, Kirill and Mureev, Sergey (2022). Towards a generic prototyping approach for therapeutically-relevant peptides and proteins in a cell-free translation system. Nature Communications, 13 (1) 260, 260. doi: 10.1038/s41467-021-27854-9
Goodall, Emily C. A., Isom, Georgia L., Rooke, Jessica L., Pullela, Karthik, Icke, Christopher, Yang, Zihao, Boelter, Gabriela, Jones, Alun, Warner, Isabel, Da Costa, Rochelle, Zhang, Bing, Rae, James, Tan, Wee Boon, Winkle, Matthias, Delhaye, Antoine, Heinz, Eva, Collet, Jean-Francois, Cunningham, Adam F., Blaskovich, Mark A., Parton, Robert G., Cole, Jeff A., Banzhaf, Manuel, Chng, Shu-Sin, Vollmer, Waldemar, Bryant, Jack A. and Henderson, Ian R. (2021). Loss of YhcB results in dysregulation of coordinated peptidoglycan, LPS and phospholipid synthesis during Escherichia coli cell growth. PLoS Genetics, 17 (12) e1009586, 1-40. doi: 10.1371/journal.pgen.1009586
Robinson, Samuel D., Kambanis, Lucas, Clayton, Daniel, Hinneburg, Hannes, Corcilius, Leo, Mueller, Alexander, Walker, Andrew A., Keramidas, Angelo, Kulkarni, Sameer S., Jones, Alun, Vetter, Irina, Thaysen-Andersen, Morten, Payne, Richard J., King, Glenn F. and Undheim, Eivind A.B. (2021). A pain-causing and paralytic ant venom glycopeptide. iScience, 24 (10) 103175, 1-21. doi: 10.1016/j.isci.2021.103175
Kojic, Marija, Gawda, Tomasz, Gaik, Monika, Begg, Alexander, Salerno-Kochan, Anna, Kurniawan, Nyoman D., Jones, Alun, Drożdżyk, Katarzyna, Kościelniak, Anna, Chramiec-Głąbik, Andrzej, Hediyeh-Zadeh, Soroor, Kasherman, Maria, Shim, Woo Jun, Sinniah, Enakshi, Genovesi, Laura A., Abrahamsen, Rannvá K., Fenger, Christina D., Madsen, Camilla G., Cohen, Julie S., Fatemi, Ali, Stark, Zornitza, Lunke, Sebastian, Lee, Joy, Hansen, Jonas K., Boxill, Martin F., Keren, Boris, Marey, Isabelle, Saenz, Margarita S., Brown, Kathleen ... Wainwright, Brandon J. (2021). Elp2 mutations perturb the epitranscriptome and lead to a complex neurodevelopmental phenotype. Nature Communications, 12 (1) 2678, 2678. doi: 10.1038/s41467-021-22888-5
Xiong, Zherui, Lo, Harriet P., McMahon, Kerrie-Ann, Martel, Nick, Jones, Alun, Hill, Michelle M., Parton, Robert G. and Hall, Thomas E. (2021). In vivo proteomic mapping through GFP-directed proximity-dependent biotin labelling in zebrafish. eLife, 10 e64631, 1-21. doi: 10.7554/elife.64631
Chislett, Mariella, Guo, Jianhua, Bond, Philip L., Jones, Alun and Yuan, Zhiguo (2020). Structural changes in cell-wall and cell-membrane organic materials following exposure to free nitrous acid. Environmental Science and Technology, 54 (16) acs.est.0c01453, 10301-10312. doi: 10.1021/acs.est.0c01453
Das Gupta, Kaustav, Shakespear, Melanie R., Curson, James E.B., Murthy, Ambika M.V., Iyer, Abishek, Hodson, Mark P., Ramnath, Divya, Tillu, Vikas A., von Pein, Jessica B., Reid, Robert C., Tunny, Kathryn, Hohenhaus, Daniel M., Moradi, Shayli Varasteh, Kelly, Gregory M., Kobayashi, Takumi, Gunter, Jennifer H., Stevenson, Alexander J., Xu, Weijun, Luo, Lin, Jones, Alun, Johnston, Wayne A., Blumenthal, Antje, Alexandrov, Kirill, Collins, Brett M., Stow, Jennifer L., Fairlie, David P. and Sweet, Matthew J. (2020). Class IIa histone deacetylases drive toll-like receptor-inducible glycolysis and macrophage inflammatory responses via pyruvate kinase M2. Cell Reports, 30 (8), 2712-2728.e8. doi: 10.1016/j.celrep.2020.02.007
Ziegman, Rebekah, Undheim, Eivind A.B., Baillie, Gregory, Jones, Alun and Alewood, Paul F. (2019). Investigation of the estuarine stonefish (Synanceia horrida) venom composition. Journal of Proteomics, 201, 12-26. doi: 10.1016/j.jprot.2019.04.002
Jin, Ai-Hua, Dutertre, Sébastien, Dutt, Mriga, Lavergne, Vincent, Jones, Alun, Lewis, Richard and Alewood, Paul (2019). Transcriptomic-proteomic correlation in the predation-evoked venom of the cone snail, Conus imperialis. Marine Drugs, 17 (3) 177, 177. doi: 10.3390/md17030177
Kojic, Marija, Gaik, Monika, Kiska, Bence, Salerno-Kochan, Anna, Hunt, Sarah, Tedoldi, Angelo, Mureev, Sergey, Jones, Alun, Whittle, Belinda, Genovesi, Laura A., Adolphe, Christelle, Brown, Darren L., Stow, Jennifer L., Alexandrov, Kirill, Sah, Pankaj, Glatt, Sebastian and Wainwright, Brandon J. (2018). Elongator mutation in mice induces neurodegeneration and ataxia-like behavior. Nature Communications, 9 (1) 3195, 3195. doi: 10.1038/s41467-018-05765-6
Khoontawad, Jarinya, Intuyod, Kitti, Rucksaken, Rucksak, Hongsrichan, Nuttanan, Pairojkul, Chawalit, Pinlaor, Porntip, Boonmars, Thidarut, Wongkham, Chaisiri, Jones, Alun, Plieskatt, Jordan, Potriquet, Jeremy, Bethony, Jeffrey M., Mulvenna, Jason and Pinlaor, Somchai (2018). Discovering proteins for chemoprevention and chemotherapy by curcumin in liver fluke infection-induced bile duct cancer. PLoS ONE, 13 (11) e0207405, e0207405. doi: 10.1371/journal.pone.0207405
Goldenberg, Jonathan, Cipriani, Vittoria, Jackson, Timothy N. W., Arbuckle, Kevin, Debono, Jordan, Dashevsky, Daniel, Panagides, Nadya, Ikonomopoulou, Maria P., Koludarov, Ivan, Li, Bin, Santana, Renan Castro, Nouwens, Amanda, Jones, Alun, Hay, Chris, Dunstan, Nathan, Allen, Luke, Bush, Brian, Miles, John J, Ge, Lilin, Kwok, Hang Fai and Fry, Bryan G (2018). Proteomic and functional variation within black snake venoms (Elapidae: Pseudechis). Comparative Biochemistry and Physiology Part C: Toxicology and Pharmacology, 205, 53-61. doi: 10.1016/j.cbpc.2018.01.001
Khoontawad, Jarinya, Pairojkul, Chawalit, Rucksaken, Rucksak, Pinlaor, Porntip, Wongkham, Chaisiri, Yongvanit, Puangrat, Pugkhem, Ake, Jones, Alun, Plieskatt, Jordan, Potriquet, Jeremy, Bethony, Jeffery, Pinlaor, Somchai and Mulvenna, Jason (2017). Differential protein expression marks the transition from infection with opisthorchis viverrini to cholangiocarcinoma. Molecular and Cellular Proteomics, 16 (5), 911-923. doi: 10.1074/mcp.M116.064576
Santana, Renan C., Perez, David, Dobson, James, Panagides, Nadya, Raven, Robert J., Nouwens, Amanda, Jones, Alun, King, Glenn F. and Fry, Bryan G. (2017). Venom profiling of a population of the theraphosid spider Phlogius crassipes reveals continuous ontogenetic changes from juveniles through adulthood. Toxins, 9 (4) 116, 116. doi: 10.3390/toxins9040116
Cui, Zhenling, Mureev, Sergey, Polinkovsky, Mark E., Tnimov, Zakir, Guo, Zhong, Durek, Thomas, Jones, Alun and Alexandrov, Kirill (2016). Combining sense and nonsense codon reassignment for site-selective protein modification with unnatural amino acids. ACS Synthetic Biology, 6 (3), 535-544. doi: 10.1021/acssynbio.6b00245
Yu, X., James, A. T., Yang, A., Jones, A., Mendoza-Porras, O., Betrix, C. -A., Ma, H. and Colgrave, M. L. (2016). A comparative proteomic study of drought-tolerant and drought-sensitive soybean seedlings under drought stress. Crop and Pasture Science, 67 (5), 528-540. doi: 10.1071/CP15314
Reeks, Timothy, Lavergne, Vincent, Sunagar, Kartik, Jones, Alun, Undheim, Eivind, Dunstan, Nathan, Fry, Bryan and Alewood, Paul F. (2016). Deep venomics of the Pseudonaja genus reveals inter- and intra-specific variation. Journal of Proteomics, 133, 20-32. doi: 10.1016/j.jprot.2015.11.019
Marta Kubala, Norwood, Suzanne, Gomez, Guillermo, Jones, Alun, Johnston, Wayne A., Yap, Alpha S.K., Mureev, Sergey and Alexandrov, Kirill (2015). Mammalian farnesyltransferase α subunit regulates vacuolar protein sorting-associated protein 4A (Vps4A) – dependent intracellular trafficking through recycling endosomes. Biochemical and Biophysical Research Communications, 468 (4), 580-586. doi: 10.1016/j.bbrc.2015.10.148
Nielsen, Daniel S., Lohman, Rink-Jan, Hoang, Huy Ngoc, Hill, Timothy A., Jones, Alun, Lucke, Andrew J. and Fairlie, David P. (2015). Flexibility versus rigidity for orally bioavailable cyclic hexapeptides. Chembiochem, 16 (16), 2289-2293. doi: 10.1002/cbic.201500441
Lavergne, Vincent, Harliwong, Ivon, Jones, Alun, Miller, David, Taft, Ryan and Alewood, Paul F. (2015). Optimised deep-targeted proteotranscriptomic profiling reveals unexplored conus toxin diversity and novel cysteine frameworks. Proceedings of the National Acadamy of Sciences of the United States of America, 112 (29), E3782-E3791. doi: 10.1073/pnas.1501334112
Nagaraj, Shiv Hiriyur, Waddell, Nicola, Madugundu, Anil K., Wood, Scott, Jones, Alun, Mandyam, Ramya, Nones, Katia, Pearson, John and Grimmond, Sean M. (2015). PGTools: a software suite for proteogenomic data analysis and visualization. Journal of Proteome Research, 14 (5), 2255-2266. doi: 10.1021/acs.jproteome.5b00029
Reeks, Timothy, Jones, Alun, Brust, Andreas, Sridharan, Sindhuja, Corcilius, Leo, Wilkinson, Brendan L., Thaysen-Andersen, Morten, Payne, Richard J., Kini, R. Manjunatha, Daly, Norelle L. and Alewood, Paul F. (2015). A defined α-Helix in the bifunctional O-Glycosylated Natriuretic Peptide TcNPa from the venom of Tropidechis carinatus. Angewandte Chemie: International Edition, 54 (16), 4828-4831. doi: 10.1002/anie.201411914
Korenkova, Vlasta, Jones, Alun , Hoy, Wendy E , Morais, Christudas , Cooper, Matthew A. and Gobe, Glenda C. (2015). Urinary biomarkers for detection of early and advanced chronic kidney disease-A pilot study. Medicinal Chemistry, 5 (2), 96-103. doi: 10.4172/2161-0444.1000249
Ali, Syed A., Jackson, Timothy N., Casewell, Nicholas R., Low, Dolyce H.W., Rossi, Sarah, Baumann, Kate, Fathinia, Behzad, Visser, Jeroen, Nouwens, Amanda, Hendrikx, Iwan, Jones, Alun and Fry, Bryan G. (2015). Extreme venom variation in Middle Eastern vipers: A proteomics comparison of Eristicophis macmahonii, Pseudocerastes fieldi and Pseudocerastes persicus. Journal of Proteomics, 116, 106-113. doi: 10.1016/j.jprot.2014.09.003
Lin, Min-Hsuan, Sivakumaran, Haran, Jones, Alun, Li, Dongsheng, Harper, Callista, Wei, Ting, Jin, Hongping, Rustanti, Lina, Meunier, Frederic A., Spann, Kirsten and Harrich, David (2014). A HIV-1 Tat mutant protein disrupts HIV-1 Rev function by targeting the DEAD-box RNA helicase DDX1. Retrovirology, 11 (1) 9, 121.1-121.16. doi: 10.1186/s12977-014-0121-9
Undheim, Eivind, Jones, Alun, Clauser, Karl R., Holland, John W., Pineda Gonzalez, Sandy, King, Glenn F and Bryan Fry (2014). Clawing through evolution: toxin diversification and convergence in the ancient lineage Chilopoda (Centipedes). Molecular Biology and Evolution, 31 (8), 2124-2148. doi: 10.1093/molbev/msu162
Undheim, Eivind A. B., Sunagar, Kartik, Hamilton, Brett R., Jones, Alun, Venter, Deon J., Fry, Bryan G. and King, Glenn F. (2014). Multifunctional warheads: diversification of the toxin arsenal of centipedes via novel multidomain transcripts. Journal of Proteomics, 102, 1-10. doi: 10.1016/j.jprot.2014.02.024
Jia, Xinying, Schulte, Leigh, Loukas, Alex, Pickering, Darren, Pearson, Mark, Mobli, Mehdi, Jones, Alun, Rosengren, Karl J., Daly, Norelle L., Gobert, Geoffrey N., Jones, Malcolm K., Craik, David J. and Mulvenna, Jason (2014). Solution structure, membrane interactions and protein binding partners of the tetraspanin Sm-TSP-2, a vaccine antigen from the human blood fluke Schistosoma mansoni. Journal of Biological Chemistry, 289 (10), 1-26. doi: 10.1074/jbc.M113.531558
Jesupret, Clémence, Baumann, Kate, Jackson, Timothy N. W., Ali, Syed Abid, Yang, Daryl C., Greisman, Laura, Kern, Larissa, Steuten, Jessica, Jouiaei, Mahdokht, Casewell, Nicholas R., Undheim, Eivind A. B., Koludarov, Ivan, Debono, Jordan, Low, Dolyce H. W., Rossi, Sarah, Panagides, Nadya, Winter, Kelly, Ignjatovic, Vera, Summerhayes, Robyn, Jones, Alun, Nouwens, Amanda, Dunstan, Nathan, Hodgson, Wayne C., Winkel, Kenneth D., Monagle, Paul and Fry, Bryan Grieg (2014). Vintage venoms: proteomic and pharmacological stability of snake venoms stored for up to eight decades. Journal of Proteomics, 105, 285-294. doi: 10.1016/j.jprot.2014.01.004
Luo, Lin, King, Nathan P., Yeo, Jeremy C., Jones, Alun and Stow, Jennifer L. (2013). Single-step protease cleavage elution for identification of protein-protein interactions from GST pull-down and mass spectrometry. Proteomics, Accepted Article (1), 1-15. doi: 10.1002/pmic.201300315
Ali, Syed A., Baumann, Kate, Jackson, Timothy N. W., Wood, Kelly, Mason, Steven, Undheim, Eivind A.B., Nouwens, Amanda, Koludarov, Ivan, Hendrikx, Iwan, Jones, Alun and Fry, Bryan Grieg (2013). Proteomic comparison of Hypnale hypnale (Hump-Nosed Pit-Viper) and Calloselasma rhodostoma (Malayan Pit-Viper) venoms. Journal of Proteomics, 91, 338-343. doi: 10.1016/j.jprot.2013.07.020
Ali, Syed A., Yang, Daryl C., Jackson, Timothy N. W., Undheim, Eivind A. B., Koludarov, Ivan, Wood, Kelly, Jones, Alun, Hodgson, Wayne C., McCarthy, Sean, Ruder, Tim and Fry, Bryan G. (2013). Venom proteomic characterization and relative antivenom neutralization of two medically important Pakistani elapid snakes (Bungarus sindanus and Naja naja). Journal of Proteomics, 89, 15-23. doi: 10.1016/j.jprot.2013.05.015
Low, Dolyce H. W., Sunagar, Kartik, Undheim, Eivind A. B., Ali, Syed A., Alagon, Alejandro C., Ruder, Tim, Jackson, Timothy N. W., Gonzalez, Sandy Pineda, King, Glenn F., Jones, Alun, Antunes, Agostinho and Fry, Bryan G. (2013). Dracula's children: molecular evolution of vampire bat venom. Journal of Proteomics, 89, 95-111. doi: 10.1016/j.jprot.2013.05.034
Fry, Bryan G., Undheim, Eivind A. B., Ali, Syed A., Jackson, Timothy N. W., Debono, Jordan, Scheib, Holger, Ruder, Tim, Morgenstern, David, Cadwallader, Luke, Whitehead, Darryl, Nabuurs, Rob, van der Weerd, Louise, Vidal, Nicolas, Roelants, Kim, Hendrikx, Iwan, Gonzalez, Sandy Pineda, Koludarov, Ivan, Jones, Alun, King, Glenn F., Antunes, Agostinho and Sunagar, Kartik (2013). Squeezers and leaf-cutters: differential diversification and degeneration of the venom system in toxicoferan reptiles. Molecular and Cellular Proteomics, 12 (7), 1881-1899. doi: 10.1074/mcp.M112.023143
Dutertre, Sebastien, Jin, Ai-Hua (Jean), Kaas, Quentin, Jones, Alun, Alewood, Paul F. and Lewis, Richard J. (2013). Deep venomics reveals the mechanism for expanded peptide diversity in cone snail venom. Molecular and Cellular Proteomics, 12 (2), 312-329. doi: 10.1074/mcp.M112.021469
Undheim, Eivind A. B., Sunagar, Kartik, Herzig, Volker, Kely, Laurence, Low, Dolyce H. W., Jackson, Timothy N. W., Jones, Alun, Kurniawan, Nyoman, King, Glenn F., Ali, Syed A., Antunes, Agostino, Ruder, Tim and Fry, Bryan G. (2013). A proteomics and transcriptomics investigation of the venom from the Barychelid spider Trittame loki (brush-foot trapdoor). Toxins, 5 (12), 2488-2503. doi: 10.3390/toxins5122488
Smith, Jennifer J., Jones, Alun and Alewood, Paul F. (2012). Mass landscapes of seven scorpion species: the first analyses of Australian species with 1,5-DAN matrix. Journal of Venom Research, 3, 7-14.
Hu, Shu-Hong, Whitten, Andrew E., King, Gordon J., Jones, Alun, Rowland, Alexander F., James, David E. and Martin, Jennifer L. (2012). The weak complex between RhoGAP protein ARHGAP22 and signal regulatory protein 14-3-3 Has 1:2 stoichiometry and a single peptide binding mode. Plos One, 7 (8) e41731, 41731-1-41731-11. doi: 10.1371/journal.pone.0041731
Xi, Li, Jin, Yaping, Parker, Edward A., Josh, Peter, Jones, Alun, Wijffels, Gene and Colgrave, Michelle L. (2012). Challenges in mass spectrometry-based quantification of bioactive peptides: A case study exploring the neuropeptide Y family. Biopolymers, 98 (4), 357-366. doi: 10.1002/bip.22109
Warren, Kylie, Wei, Ting, Li, Dongsheng, Qin, Fangyun, Warrilow, David, Lin, Min-Hsuan, Sivakumaran, Haran, Apolloni, Ann, Abbott, Catherine M., Jones, Alun, Anderson, Jenny L. and Harrich, David (2012). Eukaryotic elongation factor 1 complex subunits are critical HIV-1 reverse transcription cofactors. Proceedings of the National Academy of Sciences of USA, 109 (24), 9587-9592. doi: 10.1073/pnas.1204673109
Melino, Michelle, Gadd, Victoria L., Walker, Gene V., Skoien, Richard, Barrie, Helen D., Jothimani, Dinesh, Horsfall, Leigh, Jones, Alun, Sweet, Matthew J., Thomas, Gethin P., Clouston, Andrew D., Jonsson, Julie R. and Powell, Elizabeth E. (2012). Macrophage secretory products induce an inflammatory phenotype in hepatocytes. World Journal of Gastroenterology, 18 (15), 1732-1744. doi: 10.3748/wjg.v18.i15.1732
Mylne, Joshua S., Colgrave, Michelle L., Daly, Norelle L., Chanson, Aurelie H., Elliott, Alysha G., McCallum, Emily J., Jones, Alun and Craik, David J. (2011). Albumins and their processing machinery are hijacked for cyclic peptides in sunflower. Nature Chemical Biology, 7 (5), 257-259. doi: 10.1038/nchembio.542
Williamson, Nicholas A., Reilly, Charles, Tan, Chor-Teck, Ramarathinam, Sri-Harsha, Jones, Alun, Hunter, Christie L., Rooney, Francis R. and Purcell, Anthony W. (2011). A novel strategy for the targeted analysis of protein and peptide metabolites. Proteomics, 11 (2), 183-192. doi: 10.1002/pmic.201000474
Loo, Dorothy, Jones, Alun and Hill, Michelle M. (2010). Lectin magnetic bead array for biomarker discovery. Journal of Proteome Research, 9 (10), 5496-5500. doi: 10.1021/pr100472z
Howes, Mark T., Kirkham, Matthew, Riches, James, Cortese, Katia, Walser, Piers J., Simpson, Fiona, Hill, Michelle M., Jones, Alun, Lundmark, Richard, Lindsay, Margaret R., Hernandez-Deviez, Delia J., Hadzic, Gordana, McCluskey, Adam, Bashir, Rumasia, Liu, Libin, Pilch, Paul, McMahon, Harvey, Robinson, Phillip J., Hancock, John F., Mayor, Satyajit and Parton, Robert G. (2010). Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells. Journal of Cell Biology, 190 (4), 675-691. doi: 10.1083/jcb.201002119
Colgrave, Michelle, Gobert, Geoffrey N., Jones, Alun, Jones, Malcolm K., Loukas, Alex, Lovas, Erica M., McManus, Donald P., Moertel, Luke, Mulvenna, Jason and Nawaratna, Sujeevi (2010). Exposed proteins of the Schistosoma japonicum tegument. International Journal For Parasitology, 40 (5), 543-554. doi: 10.1016/j.ijpara.2009.10.002
Mulvenna, Jason, Sripa, Bancho, Brindley, Paul J., Gorman, Jeffrey, Jones, Malcolm K., Colgrave, Michelle L., Jones, Alun, Nawaratna, Sujeevi, Laha, Thewarach, Suttiprapa, Sutas, Smout, Michael J. and Loukas, Alex (2010). The secreted and surface proteomes of the adult stage of the carcinogenic human liver fluke Opisthorchis viverrini. Proteomics, 10 (5), 1063-1078. doi: 10.1002/pmic.200900393
Lewis, Richard J., Yang, Aijun and Jones, Alun (2009). Rapid extraction combined with LC-tandem mass spectrometry (CREM-LC/MS/MS) for the determination of ciguatoxins in ciguateric fish flesh (vol 54, pg 62, 2009). Toxicon, 54 (6), 897-897. doi: 10.1016/j.toxicon.2009.06.025
Inder, K. L., Lau, C, Loo, D, Chaudhary, N, Goodall, A, Martin, S, Jones, A, van der Hoeven, D, Parton, R. G., Hill, M. M. and Hancock, J. F. (2009). Nucleophosmin and nucleolin regulate K-Ras plasma membrane interactions and MAPK signal transduction. Journal of Biological Chemistry, 284 (41), 28410-28419. doi: 10.1074/jbc.M109.001537
Smout, M. J., Laha, T, Mulvenna, J, Sripa, B, Suttiprapa, S, Jones, A, Brindley, PJ and Loukas, A (2009). A Granulin-Like Growth Factor Secreted by the Carcinogenic Liver Fluke, Opisthorchis viverrini, Promotes Proliferation of Host Cells. PLoS Pathogens, 5 (10) e1000611, x-x. doi: 10.1371/journal.ppat.1000611
Davis, J, Jones, Al and Lewis, R. J. (2009). Remarkable inter- and intra-species complexity of conotoxins revealed by LC/MS. Peptides, 30 (7), 1222-1227. doi: 10.1016/j.peptides.2009.03.019
Gentz, M. C., Jones, A, Clement, H and King, G. F. (2009). Comparison of the peptidome and insecticidal activity of venom from a taxonomically diverse group of theraphosid spiders. Toxicon, 53 (5), 496-502. doi: 10.1016/j.toxicon.2009.01.025
Lewis, Richard J., Yang, Aijun and Jones, Alun (2009). Rapid extraction combined with LC-tandem mass spectrometry (CREM-LC/MS/MS) for the determination of ciguatoxins fish flesh. Toxicon, 54 (1), 62-66. doi: 10.1016/j.toxicon.2009.03.013
Eyles, Darryl, Cameron Anderson, Ko, Pauline, Alun Jones, Andrew Thomas, Burne, Thomas H.J., Mortensen, Preban, Bo, Norgaard-Pedersen, Bent, Hougaard, David, Michael and McGrath, John J. (2009). A sensitive LC/MS/MS assay of 25OH vitamin D₃ and 25OH vitamin D₂ in dried blood spots. Clinica Chimica Acta, 403 (1-2), 145-151. doi: 10.1016/j.cca.2009.02.005
Colgrave, Michelle L., Allingham, Peter G. and Jones, Alun (2008). Hydroxyproline quantification for the estimation of collagen in tissue using multiple reaction monitoring mass spectrometry. Journal of Chromatography A, 1212 (1-2), 150-153. doi: 10.1016/j.chroma.2008.10.011
Saska, I., Colgrave, M. L., Jones, A., Anderson, M. A. and Craik, D. J. (2008). Quantitative analysis of backbone-cyclised peptides in plants. Journal of Chromatography B, 872 (1-2), 107-114. doi: 10.1016/j.jchromb.2008.07.023
King, G. J., Jones, A., Kobe, B., Huber, T., Mouradov, D., Hume, D. A. and Ross, I. L. (2008). Identification of Disulfide-containing chemical cross-links in proteins using MALDI-TOF/TOF-MAss spectrometry. Analytical Chemistry, 80 (13), 5036-5043. doi: 10.1021/ac702277q
Riding, George A., Hill, Jonathan R., Jones, Alun, Holland, Michael K., Josh, Peter F. and Lehnert, Sigrid A. (2008). Differential proteomic analysis of bovine conceptus fluid proteins in pregnancies generated by assisted reproductive technologies. Protemics, 8 (14), 2967-2982. doi: 10.1002/pmic.200800008
Kurz, Mareike, Iturbe-Ormaetxe, Inaki, Jarrott, Russell, Cowieson, Nathan, Robin, Gautier, Jones, Alun, King, Gordon J., Frei, Patrick, Glockshuber, Rudi, O'Neill, Scott L., Heras, Begona and Martin, Jennifer L. (2008). Cloning, expression, purification and characterization of a DsbA-like protein from Wolbachia pipientis. Protein Expression and Purification, 59 (2), 266-273. doi: 10.1016/j.pep.2008.02.008
Horton, D. A., Bourne, G. T., Coughlan, J., Kaiser, S. M., Jacobs, C. M., Jones, A., Ruhmann, A., Turner, J. Y. and Smythe, M. L. (2008). Cyclic tetrapeptides via the ring contraction strategy: Chemical techniques useful for their identification. Organic & Biomolecular Chemistry, 6 (8), 1386-1395. doi: 10.1039/b800464a
Riding, George A., Jones, Alun, Holland, Michael K., Hill, Jonathan R. and Lehnert, Sigrid A. (2008). Proteomic analysis of bovine conceptus fluids during early pregnancy. Proteomics, 8 (1), 160-177. doi: 10.1002/pmic.200700465
Gunter, Jennifer H., Thomas, Elaine c., Lengefeld, Nadia, Kruger, Sarah J., Worton, Leah, Gardiner, Edith M., Jones, Alun, Barnett, Nigel L. and Whitehead, Jonathan P. (2008). Characterisation of inosine monophosphate dehydrogenase expression during retinal development: Differences between variants and isoforms. International Journal of Biochemistry & Cell Biology, 40 (9), 1716-1728. doi: 10.1016/j.biocel.2007.12.018
Velkov, Tony, Jones, Alun and Lim, Maria L. R. (2008). Ni2+-based immobilized metal ion affinity chromatography of lactose operon repressor protein from Escherichia Coli. Preparative Biochemistry and Biotechnology, 38 (4), 422-441. doi: 10.1080/10826060802325725
Kiel, Marcus, Josh, Peter, Jones, Alun, Windon, Ross, Hunt, Peter and Kongsuwan, Kritaya (2007). Identification of immuno-reactive proteins from a sheep gastrointestinal nematode, Trichostrongylus colubriformis, using two-dimensional electrophoresis and mass spectrometry. International Journal For Parasitology, 37 (13), 1419-1429. doi: 10.1016/j.ijpara.2007.04.016
Heras, B., Kurz, M., Jarrott, R., Byriel, K. A., Jones, A., Thony-Meyer, L. and Martin, J. L. (2007). Expression and crystallization of DsbA from Staphylococcus aureus. Acta Crystallographica. Section F, Structural Biology and Crystallization communications, F63 (Pt. 11), 953-956. doi: 10.1107/S174430910704821X
McMorran, Brendan J., Patat, Severine A. Ouvry, Carlin, John B., Grimwood, Keith, Jones, Alun, Armstrong, David S., Galati, John C., Cooper, Peter J., Byrnes, Catherine A., Francis, Paul W., Robertson, Colin F., Hume, David A., Borchers, Christoph H., Wainwright, Claire E. and Wainwright, Brandon J. (2007). Novel neutrophil-derived proteins in bronchoalveolar lavage fluid indicate an exaggerated inflammatory response in pediatric cystic fibrosis patients. Clinical Chemistry, 53 (10), 1782-1791. doi: 10.1373/clinchem.2007.087650
Foo, E., Morris, S. E., Parmenter, K., Young, N., Wang, H. T., Jones, A., Rameau, C., Turnbull, C. G. N. and Beveridge, C. A. (2007). Feedback regulation of xylem cytokinin content is conserved in pea and arabidopsis. Plant Physiology, 143 (3), 1418-1428. doi: 10.1104/pp.106.093708
Schnolzer, Martina, Alewood, Paul, Jones, Alun, Alewood, Dianne and Kent, Stephen B. H. (2007). In situ neutralization in boc-chemistry solid phase peptide synthesis: Rapid, high yield assembly of difficult sequences. International Journal of Peptide Research And Therapeutics, 13 (1-2), 31-44. doi: 10.1007/s10989-006-9059-7
Khan, Seema, Hsu, Rachel, Jones, Alun, Ross, Ian L., Hart, Derek N.J. and Kato, Masato (2006). Identification of the dominant translation start site in the attB1 sequence of the pET-DEST42 Gateway vector. Protein Expression And Purification, 49 (1), 102-107. doi: 10.1016/j.pep.2006.05.001
Richards, Ayanthi A., Stephens, Tim, Charlton, Hayley K., Jones, Alun, Macdonald, Graeme A., Prins, Johannes B. and Whitehead, Jonathan P. (2006). Adiponectin multimerization is dependent on conserved lysines in the collagenous domain: Evidence for regulation of multimerization by alterations in posttranslational modifications. Molecular Endocrinology, 20 (7), 1673-1687. doi: 10.1210/me.2005-0390
Kappler, Ulrike, Hanson, Graeme R., Jones, Alun and McEwan, Alastair G. (2005). A recombinant diheme SoxAX cytochrome - Implications for the relationship between EPR signals and modified heme-ligands. Febs Letters, 579 (11), 2491-2498. doi: 10.1016/j.febslet.2005.03.060
Colgrave, M. L., Jones, A. and Craik, D. J. (2005). Peptide quantification by matrix-assisted laser desorption ionisation time-of-flight mass spectrometry: Investigations of the cyclotide kalata B1 in biological fluids. Journal of Chromatography A, 1091 (1-2), 187-193. doi: 10.1016/j.chroma.2005.07.094
van den Brenk, Anna L., Tyndall, Joel D. A., Cusack, Rodney M., Jones, Alun, Fairlie, David P., Gahan, Lawrence R. and Hanson, Graeme R. (2004). Formation of mononuclear and chloro-bridged binuclear copper(II) complexes of patellamide D, a naturally occurring cyclic peptide: influence of anion and solvent. Journal of Inorganic Biochemistry, 98 (11), 1857-1866. doi: 10.1016/j.jinorgbio.2004.08.005
Loughnan, M. L., Nicke, A., Jones, A., Adams, D. J., Alewood, P. F. and Lewis, R. J. (2004). Chemical and functional identification and characterization of novel sulfated alpha-conotoxins from the cone snail Conus anemone. Journal of Medicinal Chemistry, 47 (5), 1234-1241. doi: 10.1021/jm031010o
Blanchfield, J. T., Dutton, J. T., Hogg, R. C., Gallagher, O. P., Craik, D. J., Jones, A., Adams, D. J., Lewis, R. J., Alewood, P. F. and Toth, I. (2003). Synthesis, structure elucidation, in vitro biological activity, toxicity, and Caco-2 cell permeability of lipophilic analogues of α-conotoxin MII. Journal of Medicinal Chemistry, 46 (7), 1266-1272. doi: 10.1021/jm020426j
Wong, AK, Ross, BP, Chan, YN, Artursson, P, Lazorova, L, Jones, A and Toth, I (2002). Determination of transport in the Caco-2 cell assay of compounds varying in lipophilicity using LC-MS: enhanced transport of Leu-enkephalin analogues. European Journal of Pharmaceutical Sciences, 16 (3), 113-118. doi: 10.1016/S0928-0987(02)00078-7
Pottier, Ivannah, Vernoux, Jean-Paul, Jones, Alun and Lewis, Richard J. (2002). Characterisation of multiple Caribbean ciguatoxins and congeners in individual specimens of horse-eye jack (Caranx latus) by high-performance liquid chromatography/mass spectrometry. Toxicon, 40 (7) 1715, 929-939. doi: 10.1016/S0041-0101(02)00088-0
Bourne, Gregory T., Golding, Simon W., McGeary, Ross P., Meutermans, Wim D. F., Jones, Alun, Marshall, Garland R., Alewood, Paul F. and Smythe, Mark L. (2001). The development and application of a novel safety-catch linker for BOC-based assembly of libraries of cyclic peptides. Journal of Organic Chemistry, 66 (23), 7706-7713. doi: 10.1021/jo010580y
Hill, J. M., Atkins, A. R., Loughnan, M. L., Jones, A., Adams, D. A., Martin, R. C., Lewis, R. J., Craik, D. J. and Alewood, P. F. (2000). Conotoxin TVIIA, a novel peptide from the venom of Conus tulipa - 1. Isolation, characterization and chemical synthesis. European Journal of Biochemistry, 267 (15), 4642-4648. doi: 10.1046/j.1432-1327.2000.01508.x
Lewis, Richard J., Nielsen, Katherine J., Craik, David J., Loughnan, Marion L., Adams, Denise A., Sharpe, Iain A., Luchian, Tudor, Adams, David J., Bond, Trudy, Thomas, Linda, Jones, Alun, Matheson, Jodi-Lea, Drinkwater, Roger, Andrews, Peter R. and Alewood, Paul F. (2000). Novel omega-conotoxins from Conus catus discriminate among neuronal calcium channel subtypes. Journal of Biological Chemistry, 275 (45), 35335-35344. doi: 10.1074/jbc.M002252200
Lewis, R., Jones, A. and Vernoux, J. (1999). HPLC/Tandem Electrospray Mass Spectrometry for the Determination of Sub-ppb Levels of Pacific and Caribbean Ciguatoxins in Crude Extracts of Fish. Analytical Chemistry, 71 (1), 247-250. doi: 10.1021/ac980598h
Loughnan, Marion, Bond, Trudy, Atkins, Anne, Cuevas, Javier, Adams, David J., Broxton, Natalie M., Livett, Bruce G., Down, John G., Jones, Alun, Alewood, Paul F. and Lewis, Richard J. (1998). alpha-conotoxin EpI, a novel sulfated peptide from Conus episcopatus that selectively targets neuronal nicotinic acetylcholine receptors. Journal of Biological Chemistry, 273 (25), 15667-15674. doi: 10.1074/jbc.273.25.15667
Taylor, Paul J., Jones, Alun, Balderson, Glenda A., Lynch, Steve V., Norris, Ross L.G. and Pond, Susan M. (1996). Sensitive, specific quantitative analysis of tacrolimus (FK506) in blood by liquid chromatography-electrospray tandem mass spectrometry. Clinical Chemistry, 42 (2), 279-285.
Dancer R.J. and Jones A. (1995). Binding of the immunosuppressant peptide cyclosporine a to calcium, zinc and copper. Is cyclosporine a an ionophore?. Australian Journal of Chemistry, 48 (11), 1835-1841. doi: 10.1071/CH9951835
Holmes M.J., Lewis R.J., Jones A. and Hoy A.W.W. (1995). Cooliatoxin, the first toxin from Coolia monotis (dinophyceae). Natural Toxins, 3 (5), 355-362. doi: 10.1002/nt.2620030506
Gooley, A. A., Packer, N. H., Pisano, A., Redmond, J. W., Williams, K. L., Jones, A., Loughnan, M. and Alewood, P. F. (1995). Characterisation of individual N-and O-linked glycosylation sites using Edman degradation. Techniques in Protein Chemistry, 6 (C), 83-90. doi: 10.1016/S1080-8914(06)80013-X
van den Brenk, Anna L., Byriel, Karl A., Fairlie, David P., Gahan, Lawrence R., Hanson, Graeme R., Hawkins, Clifford J., Jones, Alun, Kennard, Colin H. L., Moubaraki, Boujemaa and Murray, Keith S. (1994). Crystal Structure, Electrospray Ionization Mass Spectrometry, Electron Paramagnetic Resonance and Magnetic Susceptibility Study of [Cu2(ascidH2) (1,2-mCO3)(H2O)2].2H2O, the Biscopper (II) Complex of Ascidiacyclamide (ascidH4), a Cyclic Peptide Isolated fr. Inorganic Chemistry, 33 (16), 3549-3557. doi: 10.1021/ic00094a019
Van den Brenk, Anna L., Fairlie, David P., Hanson, Graeme R., Gahan, Lawrence R., Hawkins, Clifford J. and Jones, Alun (1994). Binding of copper(II) to the cyclic octapeptide patellamide D. Inorganic Chemistry, 33 (10), 2280-2289. doi: 10.1021/ic00088a034
Schnölzer, Martina, Jones, Alun, Alewood, Paul F. and Kent, Stephen B.H. (1992). Ion-spray tandem mass spectrometry in peptide synthesis: Structural characterization of minor by-products in the synthesis of ACP(65-74). Analytical Biochemistry, 204 (2), 335-343. doi: 10.1016/0003-2697(92)90249-7
Alewood P.F., Brinkworth R.I., Dancer R.J., Garnham B., Jones A. and Kent S.B.H. (1992). Solid phase synthesis of hydroxyethylamine peptide bond isosteres: Synthesis of the potent HIV-1 protease inhibitor JG365. Tetrahedron Letters, 33 (7), 977-980. doi: 10.1016/S0040-4039(00)91592-2
Conference Papers
Pineda, Sandy S., Jones, Alun, Nicholson, Graham M., Escoubas, Pierre, Mattick, John S. and King, Glenn F. (2012). Understanding the chemical diversity of spider venoms using a combined genomic, transcriptomic and proteomic approach. 17th World Congress of the International-Society-on-Toxinology (IST)/Venom Week/4th International Scientific Symposium on All Things Venomous, Honolulu, Hawaii, United States, 8-13 July 2012. Kidlington, Oxford, United Kingdom: Pergamon. doi: 10.1016/j.toxicon.2012.04.060
Morgenstern, David, Hamilton, Brett, Sher, Daniel, Jones, Alun, Mattius, Gideon, Zlotkin, Eli, Venter, Deon and King, Glenn F. (2012). The bio-logic of venom complexity. 17th World Congress of the International-Society-on-Toxinology (IST)/Venom Week/4th International Scientific Symposium on All Things Venomous, Honolulu, Hawaii, United States, 8-13 July 2012. Kidlington, Oxford, United Kingdom: Pergamon. doi: 10.1016/j.toxicon.2012.04.285
Undheim, Eivind A. B., Jones, Alun, Holland, John W., Morales, Rodrigo A. V., Winnen, Brit, Fry, Bryan G. and King, Glenn F. (2012). Centipede venoms: Old and unusual. 17th World Congress of the International-Society-on-Toxinology (IST)/Venom Week/4th International Scientific Symposium on All Things Venomous, Honolulu, Hawaii, United States, 8-13 July 2012. Kidlington, Oxford, United Kingdom: Pergamon. doi: 10.1016/j.toxicon.2012.04.065
Broadbent, J., Stansfield, S., Sampson, D., Jones, A., Shooter, G., Walsh, T. and Upton, Z. (2012). Proteomic systems analysis of the proximal fluid from chronic wounds implies perturbation of oxidative systems and persistent neutrophil influx. Conjoint 3rd Australasian Wound & Tissue Repair Society and 9th Australasian Society for Dermatology Research Conference, Sydney, NSW, Australia, 22-24 May 2012. Hoboken, NJ, United States: Wiley-Blackwell. doi: 10.1111/j.1524-475X.2012.00835.x
King, G. F., Jones, A., Cowieson, N. P., Huber, T. L., Kobe, B. and Ross, I. L. (2006). Rapid identification of DTSSP crosslinked peptides using LCMALDI Tof-Tof mass spectrometry. ComBio 2006, Brisbane, Australia, 24-28 Sept, 2006. Kent Town, Australia: Australian Society for Biochemistry and Molecular Biology.