Researcher biography

Dr Weijun Xu is a computational chemist and biochemist. He completed Bachelor of Science (Hons in Biochemistry and Molecular Biology) from the University of Queensland. His research involved virtual screening against different proteases including SARS 3CLpro, viral serine proteases (West nile virus and Dengue NS2B-NS3 proteases), a human cysteine protease: caspase-1, and a human kinase BRAF(V600E) to discover non-peptidic organic compounds as putative inhibitors. He was a lecturer from the school of Chemical and Life Sciences in Singapore Polytechnic from 2006 to 2013.

Weijun Xu studied his Ph.D (Computational Chemistry) under the supervision of Professor David Fairlie in IMB. Weijun Xu published in multi-disciplinary journals incudling molecular modeling, medicinal chemistry, pharmacology, and immunology. His Ph.D research focuses on computer modeling of protein-ligand and protein-protein interactions on cell surfaces. These targets include GPCRs such as PAR2, C3aR, C5aR, and GLP1R. He also focused on a new immune cell named mucosal associated invariant T (MAIT) cell. The work targeting MAIT cell culminated in the first discovery of approved drugs and drug-like compounds can modulate MAIT cell functions.