Dr Andrew White
Higher degree by research (PhD) student
Institute for Molecular Bioscience
+61 7 334 62023
Journal Articles
Koehbach, Johannes, Muratspahić, Edin, Ahmed, Zakaria M, White, Andrew M, Tomašević, Nataša, Durek, Thomas, Clark, Richard J, Gruber, Christian W and Craik, David J (2024). Chemical synthesis of grafted cyclotides using a “plug and play” approach. RSC Chemical Biology, 5 (6), 567-571. doi: 10.1039/d4cb00008k
Muratspahić, Edin, Aslanoglou, Despoina, White, Andrew M., Draxler, Claudia, Kozisek, Xaver, Farooq, Zara, Craik, David J., McCormick, Peter J., Durek, Thomas and Gruber, Christian W. (2023). Development of melanocortin 4 receptor agonists by exploiting animal-derived macrocyclic, disulfide-rich peptide scaffolds. ACS Pharmacology and Translational Science, 6 (10), 1373-1381. doi: 10.1021/acsptsci.3c00090
Muratspahić, Edin, White, Andrew M., Ciotu, Cosmin I., Hochrainer, Nadine, Tomašević, Nataša, Koehbach, Johannes, Lewis, Richard J., Spetea, Mariana, Fischer, Michael J. M., Craik, David J. and Gruber, Christian W. (2023). Development of a selective peptide κ-opioid receptor antagonist by late-stage functionalization with cysteine staples. Journal of Medicinal Chemistry, 66 (17), 11843-11854. doi: 10.1021/acs.jmedchem.3c00426
Palombi, Isabella R., Lawrence, Nicole, White, Andrew M., Gare, Caitlin L., Craik, David J., McMorran, Brendan J. and Malins, Lara R. (2023). Development of antiplasmodial peptide–drug conjugates using a human protein-derived cell-penetrating peptide with selectivity for infected cells. Bioconjugate Chemistry, 34 (6), 1105-1113. doi: 10.1021/acs.bioconjchem.3c00147
White, Andrew M., Dellsén, Anita, Larsson, Niklas, Kaas, Quentin, Jansen, Frank, Plowright, Alleyn T., Knerr, Laurent, Durek, Thomas and Craik, David J. (2022). Late-stage functionalization with cysteine staples generates potent and selective melanocortin receptor-1 agonists. Journal of Medicinal Chemistry, 65 (19), 12956-12969. doi: 10.1021/acs.jmedchem.2c00793
Winters, Anne E., Chan, Weili, White, Andrew M., van den Berg, Cedric P., Garson, Mary J. and Cheney, Karen L. (2022). Weapons or deterrents? Nudibranch molluscs use distinct ecological modes of chemical defence against predators. Journal of Animal Ecology, 91 (4), 831-844. doi: 10.1111/1365-2656.13643
Jakob, Valentin, Zoller, Ben G. E., Rinkes, Julia, Wu, Yingwen, Kiefer, Alexander F., Hust, Michael, Polten, Saskia, White, Andrew M., Harvey, Peta J., Durek, Thomas, Craik, David J., Siebert, Andreas, Kazmaier, Uli and Empting, Martin (2022). Phage display-based discovery of cyclic peptides against the broad spectrum bacterial anti-virulence target CsrA. European Journal of Medicinal Chemistry, 231 114148, 114148. doi: 10.1016/j.ejmech.2022.114148
Durek, Thomas, Kaas, Quentin, White, Andrew M., Weidmann, Joachim, Fuaad, Abdullah Ahmad, Cheneval, Olivier, Schroeder, Christina I., de Veer, Simon J., Dellsén, Anita, Österlund, Torben, Larsson, Niklas, Knerr, Laurent, Bauer, Udo, Plowright, Alleyn T. and Craik, David J. (2021). Melanocortin 1 receptor agonists based on a bivalent, bicyclic peptide framework. Journal of Medicinal Chemistry, 64 (14) acs.jmedchem.1c00095, 9906-9915. doi: 10.1021/acs.jmedchem.1c00095
Veer, Simon J., White, Andrew M. and Craik, David J. (2020). Der Sonnenblumen‐Trypsin‐Inhibitor 1 (SFTI‐1) in der Chemie und Biologie. Angewandte Chemie, 133 (15), 8128-8151. doi: 10.1002/ange.202006919
de Veer, Simon J., White, Andrew M. and Craik, David (2020). Sunflower trypsin inhibitor-1 (SFTI-1): sowing seeds in the fields of chemistry and biology. Angewandte Chemie (International Edition), 59 (15), 2-24. doi: 10.1002/anie.202006919
White, Andrew M., Veer, Simon J., Wu, Guojie, Harvey, Peta J., Yap, Kuok, King, Gordon J., Swedberg, Joakim E., Wang, Conan K., Law, Ruby H. P., Durek, Thomas and Craik, David J. (2020). Innentitelbild: Application and Structural Analysis of Triazole‐Bridged Disulfide Mimetics in Cyclic Peptides (Angew. Chem. 28/2020). Angewandte Chemie, 132 (28), 11258-11258. doi: 10.1002/ange.202006713
White, Andrew M., Veer, Simon J., Wu, Guojie, Harvey, Peta J., Yap, Kuok, King, Gordon J., Swedberg, Joakim E., Wang, Conan K., Law, Ruby H. P., Durek, Thomas and Craik, David J. (2020). Inside Cover: Application and Structural Analysis of Triazole‐Bridged Disulfide Mimetics in Cyclic Peptides (Angew. Chem. Int. Ed. 28/2020). Angewandte Chemie International Edition, 59 (28), 11162-11162. doi: 10.1002/anie.202006713
White, Andrew M., Veer, Simon J., Wu, Guojie, Harvey, Peta J., Yap, Kuok, King, Gordon J., Swedberg, Joakim E., Wang, Conan K., Law, Ruby H. P., Durek, Thomas and Craik, David J. (2020). Application and structural analysis of triazole‐bridged disulfide mimetics in cyclic peptides. Angewandte Chemie International Edition, 132 (28) anie.202003435, 11369-11373. doi: 10.1002/anie.202003435
Li, Choi Yi, de Veer, Simon J., White, Andrew M., Chen, Xingchen, Harris, Jonathan M., Swedberg, Joakim E. and Craik, David J. (2019). Amino acid scanning at P5′ within the Bowman–Birk inhibitory loop reveals specificity trends for diverse serine proteases. Journal of Medicinal Chemistry, 62 (7), 3696-3706. doi: 10.1021/acs.jmedchem.9b00211
Winters, Anne E., White, Andrew M., Cheney, Karen L. and Garson, Mary J. (2019). Geographic variation in diterpene-based secondary metabolites and level of defence in an aposematic nudibranch, Goniobranchus splendidus. Journal of Molluscan Studies, 85 (1), 41-47. doi: 10.1093/mollus/eyy057
White, A. M., Dao, K., Vrubliauskas, D., Konst, Z. A., Pierens, G. K., Mándi, A., Andrews, K. T., Skinner-Adams, T. S., Clarke, M. E., Narbutas, P. T., Sim, D. C.-M., Cheney, K. L., Kurtán, T., Garson, M. J. and Vanderwal, C. D. (2018). Correction to catalyst-controlled stereoselective synthesis secures the structure of the antimalarial isocyanoterpene pustulosaisonitrile-1. The Journal of Organic Chemistry, 83 (16), 9571-9572. doi: 10.1021/acs.joc.8b01819
Winters, Anne E., Wilson, Nerida G., van den Berg, Cedric P., How, Martin J., Endler, John A., Marshall, N. Justin, White, Andrew M., Garson, Mary J. and Cheney, Karen L. (2018). Toxicity and taste: unequal chemical defences in a mimicry ring. Proceedings of the Royal Society B: Biological Sciences, 285 (1880) 20180457, 20180457. doi: 10.1098/rspb.2018.0457
Durek, Thomas, Cromm, Philipp M., White, Andrew M., Schroeder, Christina I., Kaas, Quentin, Weidmann, Joachim, Ahmad Fuaad, Abdullah, Cheneval, Olivier, Harvey, Peta J., Daly, Norelle L., Zhou, Yang, Dellsén, Anita, Österlund, Torben, Larsson, Niklas, Knerr, Laurent, Bauer, Udo, Kessler, Horst, Cai, Minying, Hruby, Victor J., Plowright, Alleyn T. and Craik, David J. (2018). Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1. Journal of Medicinal Chemistry, 61 (8), 3674-3684. doi: 10.1021/acs.jmedchem.8b00170
Winters, Anne E., White, Andrew M., Dewi, Ariyanti S., Mudianta, I. Wayan, Wilson, Nerida G., Forster, Louise C., Garson, Mary J. and Cheney, Karen L. (2018). Distribution of defensive metabolites in nudibranch molluscs. Journal of Chemical Ecology, 44 (4), 384-396. doi: 10.1007/s10886-018-0941-5
Forster, Louise C., White, Andrew M., Cheney, Karen L. and Garson, Mary J. (2018). Oxygenated Terpenes from the Indo-Pacific Nudibranchs Goniobranchus splendidus and Goniobranchus collingwoodi. Natural Product Communications, 13 (3), 299-302. doi: 10.1177/1934578x1801300309
White, Andrew M., Dao, Kathy, Vrubliauskas, Darius, Könst, Zef A., Pierens, Gregory K., Mándi, Attila, Andrews, Katherine T., Skinner-Adams, Tina S., Clarke, Mary E., Narbutas, Patrick T., Sim, Desmond C.-M., Cheney, Karen L., Kurtán, Tibor, Garson, Mary J. and Vanderwal, Christopher D. (2017). Catalyst-Controlled Stereoselective Synthesis Secures the Structure of the Antimalarial Isocyanoterpene Pustulosaisonitrile-1. Journal of Organic Chemistry, 82 (24) acs.joc.8b01819, 13313-13323. doi: 10.1021/acs.joc.7b02421
Sim, Desmond C.-M., Wayan Mudianta, I., White, Andrew M., Martiningsih, Ni Wayan, Loh, Jasmine J. M., Cheney, Karen L. and Garson, Mary J. (2017). New sesquiterpenoid isonitriles from three species of phyllidid nudibranchs. Fitoterapia, 126, 69-73. doi: 10.1016/j.fitote.2017.10.003
Forster, Louise C., Pierens, Gregory K., White, Andrew M., Cheney, Karen L., Dewapriya, Pradeep, Capon, Robert J. and Garson, Mary J. (2017). Cytotoxic spiroepoxide lactone and its putative biosynthetic precursor from Goniobranchus Splendidus. ACS Omega, 2 (6), 2672-2677. doi: 10.1021/acsomega.7b00641
White, Andrew M. and Craik, David J. (2016). Discovery and optimization of peptide macrocycles. Expert Opinion on Drug Discovery, 11 (12), 1151-1163. doi: 10.1080/17460441.2016.1245720
White, Andrew M., Dewi, Ariyanti S., Cheney, Karen L., Winters, Anne E., Blanchfield, Joanne T. and Garson, Mary J. (2016). Oxygenated diterpenes from the Indo-Pacific nudibranchs Goniobranchus splendidus and Ardeadoris egretta. Natural Product Communications, 11 (7), 921-924. doi: 10.1177/1934578X1601100714
Cheney, Karen L., White, Andrew, Mudianta, I. Wayan, Winters, Anne E., Quezada, Michelle, Capon, Robert J., Mollo, Ernesto and Garson, Mary J. (2016). Choose your weaponry: selective storage of a single toxic compound, Latrunculin A, by closely related nudibranch molluscs. PLoS One, 11 (1) A1222, 1-16. doi: 10.1371/journal.pone.0145134
White, Andrew M., Pierens, Gregory K., Forster, Louise C., Winters, Anne E., Cheney, Karen L. and Garson, Mary J. (2015). Rearranged Diterpenes and Norditerpenes from Three Australian Goniobranchus Mollusks.. Journal of Natural Products, 79 (3), 477-483. doi: 10.1021/acs.jnatprod.5b00866
Hirayama, Yuichiro, Katavic, Peter L., White, Andrew M., Pierens, Gregory K., Lambert, Lynette K., Winters, Anne E., Kigoshi, Hideo, Kita, Masaki and Garson, Mary J. (2015). New Cytotoxic Norditerpenes from the Australian Nudibranchs Goniobranchus Splendidus and Goniobranchus Daphne. Australian Journal of Chemistry, 69 (2), 136-144. doi: 10.1071/CH15203
White, Andrew M., Pierens, Gregory K., Skinner-Adams, Tina, Andrews, Katherine T., Bernhardt, Paul V., Krenske, Elizabeth H., Mollo, Ernesto and Garson, Mary J. (2015). Antimalarial isocyano and isothiocyanato sesquiterpenes with tri- and bicyclic skeletons from the nudibranch Phyllidia ocellata. Journal of Natural Products, 78 (6), 1422-1427. doi: 10.1021/acs.jnatprod.5b00354
Mudianta, I. Wayan, White, Andrew M. and Garson, Mary J. (2015). Oxygenated Terpenes from Indo-Pacific Nudibranchs: Scalarane Sesterterpenes from Glossodoris hikuerensis and 12-Acetoxy Dendrillolide A from Goniobranchus albonares. Natural Product Communications, 10 (6), 865-868. doi: 10.1177/1934578X1501000617
Conference Papers
White, Andrew, Deveer, Simon, Swedberg, Joakim, Durek, Thomas and Craik, David (2018). Development of serine protease inhibitors using the 1,2,3-triazole motif as a disulfide mimetic in the cyclic peptide sunflower trypsin inhibitor-1. 35th European Peptide Symposium, Dublin City University, Ireland, 26-31 August 2018. Oxford, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.3127
Mudianta, I. Wayan, White, Andrew M., Suciati, Katavic, Peter L., Krishnaraj, Rahul R., Winters, Anne E., Mollo, Ernesto, Cheney, Karen L. and Garson, Mary J. (2014). Chemoecological studies on marine natural products: terpene chemistry from marine mollusks. IUPAC 2013: 44th World Chemistry Congress, Istanbul, Turkey, 11-16 August, 2013. Berlin, Germany: Walter de Gruyter. doi: 10.1515/pac-2013-1111
Thesis
White, Andrew (2020). Engineering of cyclic disulfide-rich peptides for applications in drug design. PhD Thesis, Institute for Molecular Bioscience, The University of Queensland. doi: 10.14264/uql.2020.487