Associate Professor Lachlan Coin is a mathematician with a research focus on developing genomics and bioinformatics tools in infectious disease and cancer. He was originally drawn by the rigour and intellectual challenge of pure mathematics but now uses his maths background as a toolkit for solving complex problems in analysing high throughput biological data.

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Researcher biography

I was awarded a PhD in bioinformatics from the University of Cambridge in 2005 for research into the evolution of protein domains. I took up a position as Reserch Council UK research fellow in the Department of Epidemiology and Public Health at Imperial College (located at St Marys Hospital), where I investigated the role of genetic variation in complex disease. In particular I developed tools for characterising copy number variation in order to better understand the role of copy number variation in complex phenotypes, which lead to the identification of copy number variants associated with obesity. I also developed tools for identification of pathways associated with disease as well as for analysing pleitropic SNPs. With Professor Mike Levin, I also investigated the use of gene expression microarrays to discover biomarkers of active tuberculosis. In 2012 I took up a research group leader position at the Institute for Molecular Bioscience at the University of Queensland. I also took up an ARC Future Fellowship in 2012.

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Medical genomics and bioinformatics