Mr Charles Ferguson

Hall, Thomas E., Ariotti, Nicholas, Lo, Harriet P., Rae, James, Ferguson, Charles, Martel, Nick, Lim, Ye-Wheen, Giacomotto, Jean and Parton, Robert G. (2023). Cell surface plasticity in response to shape change in the whole organism. Current Biology, 33 (19), 4276-4284. doi: 10.1016/j.cub.2023.08.068

Wu, Yeping, Lim, Ye-Wheen, Stroud, David A., Martel, Nick, Hall, Thomas E., Lo, Harriet P., Ferguson, Charles, Ryan, Michael T., McMahon, Kerrie-Ann and Parton, Robert G. (2023). Caveolae sense oxidative stress through membrane lipid peroxidation and cytosolic release of CAVIN1 to regulate NRF2. Developmental Cell, 58 (5), 376-397.e4. doi: 10.1016/j.devcel.2023.02.004

Rae, James, Ferguson, Charles, Ariotti, Nicholas, Webb, Richard I., Cheng, Han-Hao, Mead, James L., Riches, James D., Hunter, Dominic J.B., Martel, Nick, Baltos, Joanne, Christopoulos, Arthur, Bryce, Nicole S., Cagigas, Maria Lastra, Fonseka, Sachini, Sayre, Marcel E., Hardeman, Edna C., Gunning, Peter W., Gambin, Yann, Hall, Thomas E. and Parton, Robert G. (2021). A robust method for particulate detection of a genetic tag for 3D electron microscopy. eLife, 10 e64630, 1-17. doi: 10.7554/eLife.64630

Ariotti, Nicholas, Wu, Yeping, Okano, Satomi, Gambin, Yann, Follett, Jordan, Rae, James, Ferguson, Charles, Teasdale, Rohan D., Alexandrov, Kirill, Meunier, Frederic A., Hill, Michelle M. and Parton, Robert G. (2020). An inverted CAV1 (caveolin 1) topology defines novel autophagy-dependent exosome secretion from prostate cancer cells. Autophagy, 17 (9), 1-17. doi: 10.1080/15548627.2020.1820787

Hall, Thomas E., Martel, Nick, Ariotti, Nicholas, Xiong, Zherui, Lo, Harriet P., Ferguson, Charles, Rae, James, Lim, Ye-Wheen and Parton, Robert G. (2020). In vivo cell biological screening identifies an endocytic capture mechanism for T-tubule formation. Nature Communications, 11 (1) 3711, 3711. doi: 10.1038/s41467-020-17486-w

McMahon, Kerrie-Ann, Wu, Yeping, Gambin, Yann, Sierecki, Emma, Tillu, Vikas A., Hall, Thomas, Martel, Nick, Okano, Satomi, Moradi, Shayli Varasteh, Ruelcke, Jayde E., Ferguson, Charles, Yap, Alpha S., Alexandrov, Kirill, Hill, Michelle M. and Parton, Robert G. (2019). Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis. Nature Communications, 10 (1) 3279, 3279. doi: 10.1038/s41467-019-11111-1

Tillu, Vikas A., Lim, Ye-Wheen, Kovtun, Oleksiy, Mureev, Sergey, Ferguson, Charles, Bastiani, Michele, McMahon, Kerrie-Ann, Lo, Harriet P., Hall, Thomas E., Alexandrov, Kirill, Collins, Brett M. and Parton, Robert G. (2018). A variable undecad repeat domain in cavin1 regulates caveola formation and stability. EMBO Reports, 19 (9) e45775. doi: 10.15252/embr.201845775

Jung, WooRam, Sierecki, Emma, Bastiani, Michele, O'Carroll, Ailis, Alexandrov, Kirill, Rae, James, Johnston, Wayne, Hunter, Dominic J. B., Ferguson, Charles, Gambin, Yann, Ariotti, Nicholas and Parton, Robert G. (2018). Cell-free formation and interactome analysis of caveolae. The Journal of Cell Biology, 217 (6), 2141-2165. doi: 10.1083/jcb.201707004

Hsu, FoSheng, Spannl, Stephanie, Ferguson, Charles, Hyman, Anthony A., Parton, Robert G. and Zerial, Marino (2018). Rab5 and Alsin regulate stress-activated cytoprotective signaling on mitochondria. eLife, 7 e32282, 1-37. doi: 10.7554/eLife.32282

Xu, Dijin, Li, Yuqi, Wu, Lizhen, Li, Ying, Zhao, Dongyu, Yu, Jinhai, Huang, Tuozhi, Ferguson, Charles, Parton, Robert G., Yang, Hongyuan and Li, Peng (2018). Rab18 promotes lipid droplet (LD) growth by tethering the ER to LDs through SNARE and NRZ interactions. The Journal of Cell Biology, 217 (3), 975-995. doi: 10.1083/jcb.201704184

Johnston, Angus P. R., Rae, James, Ariotti, Nicholas, Bailey, Benjamin, Lija, Andrew, Webb, Robyn, Ferguson, Charles, Maher, Sheryl, Davis, Thomas P., Webb, Richard I., McGhee, John and Parton, Robert G. (2017). Journey to the centre of the cell: Virtual reality immersion into scientific data. Traffic (Copenhagen, Denmark), 19 (2), 105-110. doi: 10.1111/tra.12538

Mills, Richard J., Titmarsh, Drew M., Koenig, Xaver, Parker, Benjamin L., Ryall, James G., Quaife-Ryan, Gregory A., Voges, Holly K., Hodson, Mark P., Ferguson, Charles, Drowley, Lauren, Plowright, Alleyn T., Needham, Elise J., Wang, Qing-Dong, Gregorevic, Paul, Xin, Mei, Thomas, Walter G., Parton, Robert G., Nielsen, Lars K., Launikonis, Bradley S., James, David E., Elliott, David A., Porrello, Enzo R. and Hudson, James E. (2017). Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest. Proceedings of the National Academy of Sciences of the United States of America, 114 (40), E8372-E8381. doi: 10.1073/pnas.1707316114

Hirama, Takashi, Das, Raibatak, Yang, Yanbo, Ferguson, Charles, Won, Amy, Yip, Christopher M., Kay, Jason G., Grinstein, Sergio, Parton, Robert G. and Fairn, Gregory D. (2017). Phosphatidylserine dictates the assembly and dynamics of caveolae in the plasma membrane. Journal of Biological Chemistry, 292 (34), 14292-14307. doi: 10.1074/jbc.M117.791400

Lim, Ye-Wheen, Lo, Harriet P., Ferguson, Charles, Martel, Nick, Giacomotto, Jean, Gomez, Guillermo A., Yap, Alpha S., Hall, Thomas E. and Parton, Robert G. (2017). Caveolae protect notochord cells against catastrophic mechanical failure during development. Current Biology, 27 (13), 1968-1981.e7. doi: 10.1016/j.cub.2017.05.067

Kaakinen, Mika, Reichelt, Melissa E., Ma, Zhibin, Ferguson, Charles, Martel, Nick, Porrello, Enzo R., Hudson, James E., Thomas, Walter G., Parton, Robert G. and Headrick, John P. (2017). Cavin-1 deficiency modifies myocardial and coronary function, stretch responses and ischaemic tolerance: roles of NOS over-activity. Basic Research in Cardiology, 112 (3) 24, 24. doi: 10.1007/s00395-017-0613-6

Kerr, Markus C., Gomez, Guillermo A., Ferguson, Charles, Tanzer, Maria C., Murphy, James M., Yap, Alpha S., Parton, Robert G., Huston, Wilhelmina M. and Teasdale, Rohan D. (2017). Laser-mediated rupture of chlamydial inclusions triggers pathogen egress and host cell necrosis. Nature Communications, 8 (1) 14729, 14729. doi: 10.1038/ncomms14729

Pagac, Martin, Cooper, Daniel E., Qi, Yanfei, Lukmantara, Ivan E., Mak, Hoi Yin, Wu, Zengying, Tian, Yuan, Liu, Zhonghua, Lei, Mona, Du, Ximing, Ferguson, Charles, Kotevski, Damian, Sadowski, Pawel, Chen, Weiqin, Boroda, Salome, Harris, Thurl E., Liu, George, Parton, Robert G., Huang, Xun, Coleman, Rosalind A. and Yang, Hongyuan (2016). SEIPIN regulates lipid droplet expansion and adipocyte development by modulating the activity of glycerol-3-phosphate acyltransferase. Cell Reports, 17 (6), 1546-1559. doi: 10.1016/j.celrep.2016.10.037

Murray, David H., Jahnel, Marcus, Lauer, Janelle, Avellaneda, Mario J., Brouilly, Nicolas, Cezanne, Alice, Morales-Navarrete, Hernan, Perini, Enrico D., Ferguson, Charles, Lupas, Andrei N., Kalaidzidis, Yannis, Parton, Robert G., Grill, Stephan W. and Zerial, Marino (2016). An endosomal tether undergoes an entropic collapse to bring vesicles together. Nature, 537 (7618), 107-111. doi: 10.1038/nature19326

Hall, Thomas, Ariotti, Nicholas, Ferguson, Charles, Zherui, Xiong and Parton, Robert G. (2016). New transgenic lines for localization of GFP-tagged proteins by electron microscope. Zebrafish, 13 (3), 232-233. doi: 10.1089/zeb.2016.29002.hal

Sala-Vila, Aleix, Navarro-Lerida, Inmaculada, Sanchez-Alvarez, Miguel, Bosch, Marta, Calvo, Carlos, Lopez, Juan Antonio, Calvo, Enrique, Ferguson, Charles, Giacomello, Marta, Serafini, Annalisa, Scorrano, Luca, Enriquez, Jose Antonio, Balsinde, Jesus, Parton, Robert G., Vazquez, Jesus, Pol, Albert and Del Pozo, Miguel A. (2016). Interplay between hepatic mitochondria-Associated membranes, lipid metabolism and caveolin-1 in mice. Scientific Reports, 6 (1) 27351, 27351. doi: 10.1038/srep27351

Ariotti, Nicholas, Hall, Thomas, Rae, James, Ferguson, Charles, McMahon, Kerrie-Ann, Martel, Nick, Webb, Robyn E., Webb, Richard I., Teasdale, Rohan D. and Parton, Robert G. (2015). Modular detection of GFP-labeled proteins for rapid screening by electron microscopy in cells and organisms. Developmental Cell, 35 (4), 513-525. doi: 10.1016/j.devcel.2015.10.016

Takasato, Minoru, Er, Pei X., Chiu, Han S., Maier, Barbara, Baillie, Gregory J., Ferguson, Charles, Parton, Robert G., Wolvetang, Ernst J., Roost, Matthias S., de Sousa Lopes, Susana M. Chuva and Little, Melissa H. (2015). Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis. Nature, 526 (7574), 564-568. doi: 10.1038/nature15695

Parchure, Anup, Vyas, Neha, Ferguson, Charles, Parton, Robert G. and Mayor, Satyajit (2015). Oligomerization and endocytosis of Hedgehog is necessary for its efficient exovesicular secretion. Molecular Biology of The Cell, 26 (25), 1-35. doi: 10.1091/mbc.E15-09-0671

Ariotti, Nicholas, Rae, James, Leneva, Natalya, Ferguson, Charles, Loo, Dorothy, Okano, Satomi, Hill, Michelle M., Walser, Piers, Collins, Brett M. and Parton, Robert G. (2015). Molecular characterization of caveolin-induced membrane curvature. Journal of Biological Chemistry, 290 (41), 24875-24890. doi: 10.1074/jbc.M115.644336

Kalaidzidis, Inna, Miaczynska, Marta, Brewinska-Olchowik, Marta, Hupalowska, Anna, Ferguson, Charles, Parton, Robert G., Kalaidzidis, Yannis and Zerial, Marino (2015). APPL endosomes are not obligatory endocytic intermediates but act as stable cargo-sorting compartments. Journal of Cell Biology, 211 (1), 123-144. doi: 10.1083/jcb.201311117

Lo, Harriet P., Nixon, Susan Jane, Hall, Thomas Edward, Cowling, Belinda Simone, Ferguson, Charles, Morgan, Garry Patrick, Schieber, Nicole Louise, Fernandez-Rojo, Manuel Alejandro, Bastiani, Michele, Floetenmeyer, Matthias, Martel, Nick, Laporte, Jocelyn, Pilch, Paul F. and Parton, Robert (2015). The caveolin–cavin system plays a conserved and critical role in mechanoprotection of skeletal muscle. The Journal of Experimental Medicine, 212 (10), 833-849. doi: 10.1084/jem.21210oia80

Lo, Harriet P., Nixon, Susan J., Hall, Thomas E., Cowling, Belinda S., Ferguson, Charles, Morgan, Garry P., Schieber, Nicole L., Fernandez-Rojo, Manuel A., Bastiani, Michele, Floetenmeyer, Matthias, Martel, Nick, Laporte, Jocelyn, Pilch, Paul F. and Parton, Robert G. (2015). The caveolin-cavin system plays a conserved and critical role in mechanoprotection of skeletal muscle. Journal of Cell Biology, 210 (5), 833-849. doi: 10.1083/jcb.201501046

Herms, Albert, Bosch, Marta, Reddy, Babu J. N., Schieber, Nicole L., Fajardo, Alba, Ruperez, Celia, Fernandez-Vidal, Andrea, Ferguson, Charles, Rentero, Carles, Tebar, Francesc, Enrich, Carlos, Parton, Robert G., Gross, Steven P. and Pol, Albert (2015). AMPK activation promotes lipid droplet dispersion on detyrosinated microtubules to increase mitochondrial fatty acid oxidation. Nature Communications, 6 (1) 7176, 7176.1-7176.14. doi: 10.1038/ncomms8176

Kovtun, Oleksiy, Tilu, Vikas A., Jung, WooRam, Leneva, Natalya, Ariotti, Nicholas, Chaudhary, Natasha, Mandyam, Ramya A., Ferguson, Charles, Morgan, Garry P., Johnston, Wayne A., Harrop, Stephen J., Alexandrov, Kirill, Parton, Robert G. and Collins, Brett M. (2014). Structural insights into the organization of the cavin membrane coat complex. Developmental Cell, 31 (4), 405-419. doi: 10.1016/j.devcel.2014.10.002

Salloum, Shadi, Wang, Hongliang, Ferguson, Charles, Parton, Robert G. and Tai, Andrew W. (2013). Rab18 Binds to Hepatitis C Virus NS5A and Promotes Interaction between Sites of Viral Replication and Lipid Droplets. PLoS Pathogens, 9 (8) e1003513, e1003513. doi: 10.1371/journal.ppat.1003513

Kyrkou, A., Soufi, M., Bahtz, R., Ferguson, C., Bai, M., Parton, R. G., Hoffmann, I., Zerial, M., Fotsis, T. and Murphy, C. (2013). RhoD participates in the regulation of cell-cycle progression and centrosome duplication. Oncogene, 32 (14), 1831-1842. doi: 10.1038/onc.2012.195

Kyrkou, Athena, Soufi, Maria, Blatz, Ramona, Ferguson, Charles, Bai, Maria, Parton, Robert G., Hoffman, Ingrid, Zerial, Marino, Fotsis, Theodore and Murphy, Carol (2013). The RhoD to centrosomal duplication. Small GTPases, 4 (2), 116-122. doi: 10.4161/sgtp.23707

Walser, Piers, Ariotti, Nicholas, Howes, Mark, Ferguson, Charles, Webb, Richard, Schwudke, Dominik, Leneva, Natalya, Cho, Kwang-Jin, Cooper, Leanne, Rae, James, Floetenmeyer, Matthias, Oorschot, Viola M. J., Skoglund, Ulf, Simons, Kai, Hancock, John F. and Parton, Robert G. (2012). Constitutive formation of caveolae in a bacterium. Cell, 150 (4), 752-763. doi: 10.1016/j.cell.2012.06.042

Fernandez Rojo, Manuel Alejandro, Restall, Christina, Ferguson, Charles, Martel, Nick, Martin, Sally, Bosch, Marta, Kassan, Adam, Leong, Gary M., Martin, Sheree D., McGee, Sean L., Muscat, George E., Anderson, Robin L., Enrich, Carlos, Pol, Albert and Parton, Robert G. (2012). Caveolin-1 orchestrates the balance between glucose and lipid-dependent energy metabolism: Implications for liver regeneration. Hepatology, 55 (5), 1574-1584. doi: 10.1002/hep.24810

Ashe, Alyson, Butterfield, Natalie C., Town, Liam, Courtney, Andrew D., Cooper, Ashley N., Ferguson, Charles, Barry, Rachael, Olsson, Fredrik, Liem, Karel F., Parton, Robert G., Wainwright, Brandon J., Anderson, Kathryn V., Whitelaw, Emma and Wicking, Carol (2012). Mutations in mouse Ift144 model the craniofacial, limb and rib defects in skeletal ciliopathies. Human Molecular Genetics, 21 (8) ddr613, 1808-1823. doi: 10.1093/hmg/ddr613

Fei, Weihua, Shui, Guanghou, Zhang, Yuxi, Krahmer, Natalie, Ferguson, Charles, Kapterian, Tamar S., Lin, Ruby C., Dawes, Ian W., Brown, Andrew J., Li, Peng, Huang, Xun, Parton, Robert G., Wenk, Markus R., Walther, Tobias C. and Yang, Hongyuan (2011). A role for phosphatidic acid in the formation of "supersized" lipid droplets. Plos Genetics, 7 (7) e1002201, e1002201.1-e1002201.11. doi: 10.1371/journal.pgen.1002201

Du, Ximing, Kumar, Jaspal, Ferguson, Charles, Schulz, Timothy A., Ong, Yan Ong, Hong, Wanjin, Prinz, William A., Parton, Robert G., Brown, Andrew J. and Yang, Hongyuan (2011). A role for oxysterol-binding protein-related protein 5 in endosomal cholesterol trafficking. Journal of Cell Biology, 192 (1), 121-135. doi: 10.1083/jcb.201004142

Smutny, Michael, Cox, Hayley L., Leerberg, Joanne M., Kovacs, Eva M., Conti, Mary Anne, Ferguson, Charles, Hamilton, Nicholas A., Parton, Robert G., Adelstein, Robert S. and Yap, Alpha S. (2010). Myosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherens. Nature Cell Biology, 12 (7), 696-702. doi: 10.1038/ncb2072

Yan, Y, Johnston, APR, Dodds, SJ, Kamphuis, MMJ, Ferguson, C, Parton, RG, Nice, EC, Heath, JK and Caruso, F (2010). Uptake and intracellular fate of disulfide-bonded polymer hydrogel capsules for doxorubicin delivery to colorectal cancer cells. ACS Nano, 4 (5), 2928-2936. doi: 10.1021/nn100173h

Downes, Meredith, Francois, Mathias, Ferguson, Charles, Parton, Robert G. and Koopman, Peter (2009). Vascular defects in a mouse model of hypotrichosis-lymphedema-telangiectasia syndrome indicate a role for SOX18 in blood vessel maturation. Human Molecular Genetics, 18 (15), 2839-2850. doi: 10.1093/hmg/ddp219

Lingwood, Daniel, Schuck, Sebastian, Ferguson, Charles and Gerl, Mathias J. (2009). Generation of cubic membranes by controlled homotypic interaction of membrane proteins in the endoplasmic reticulum. Journal of Biological Chemistry, 284 (18), 12041-12048. doi: 10.1074/jbc.M900220200

Kirkham, Matthew, Nixon, Susan J., Howes, Mark T., Abi-Rached, Laurent, Wakeham, Diane E., Hanzal-Bayer, Michael, Ferguson, Charles, Hill, Michelle M., Fernandez-Rojo, Manuel, Brown, Deborah A., Hancock, John F., Brodsky, Frances M. and Parton, Robert G. (2008). Evolutionary analysis and molecular dissection of caveola biogenesis. Journal of Cell Science, 121 (12), 2075-2086. doi: 10.1242/jcs.024588

Richter, T., Floetenmeyer, M., Ferguson, C., Galea, J., Goh, J., Lindsay, M. R., Morgan, G. P., Marsh, B. J. and Parton, R. G. (2008). High-resolution 3D quantitative analysis of caveolar ultrastructure and caveola-cytoskeleton interactions. Traffic, 9 (6), 893-939. doi: 10.1111/j.1600-0854.2008.00733.x

Sobo, Komla, Le Blanc, Isabelle, Luyet, Pierre-Philippe, Fivaz, Marc, Ferguson, Charles, Parton, Robert G., Gruenberg, Jean and van der Goot, F. Gisou (2007). Late Endosomal Cholesterol Accumulation Leads to Impaired Intra-Endosomal Trafficking. PLoS One, 2 (9) e851, e851. doi: 10.1371/journal.pone.0000851

Castner, G. and Ferguson, C. (2000). The effect of transaction costs on the decision to replace 'off-the-shelf' software: The role of software diffusion and infusion. Information Systems Journal, 10 (1), 65-83. doi: 10.1046/j.1365-2575.2000.00071.x

Niebert, Marcus, Riches, James, Howes, Mark, Ferguson, Charles, Parton, Robert G., Middelberg, Anton P. J., Rintoul, Llew and Fredericks, Peter M. (2007). Hybrid organic-inorganic nanoparticles: controlled incorporation of gold nanoparticles into virus-like particles and application in surface-enhanced Raman spectroscopy.. SPIE International Symposium on Smart Materials, Nano- and Micro-Smart System, Adelaide, Australia, December 11-13, 2006. Bellingham, WA, United States: S P I E - International Society for Optical Engineering. doi: 10.1117/12.695578

Mr Charles Ferguson

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