Mr James Rae
Senior Research Assistant
Institute for Molecular Bioscience
+61 7 334 62335
Publications
Journal Articles
Morales-Paytuví, Frederic, Fajardo, Alba, Ruiz-Mirapeix, Carles, Rae, James, Tebar, Francesc, Bosch, Marta, Enrich, Carlos, Collins, Brett M., Parton, Robert G. and Pol, Albert (2023). Early proteostasis of caveolins synchronizes trafficking, degradation, and oligomerization to prevent toxic aggregation. Journal of Cell Biology, 222 (9). doi: 10.1083/jcb.202204020
Goodall, Emily C. A., Isom, Georgia L., Rooke, Jessica L., Pullela, Karthik, Icke, Christopher, Yang, Zihao, Boelter, Gabriela, Jones, Alun, Warner, Isabel, Da Costa, Rochelle, Zhang, Bing, Rae, James, Tan, Wee Boon, Winkle, Matthias, Delhaye, Antoine, Heinz, Eva, Collet, Jean-Francois, Cunningham, Adam F., Blaskovich, Mark A., Parton, Robert G., Cole, Jeff A., Banzhaf, Manuel, Chng, Shu-Sin, Vollmer, Waldemar, Bryant, Jack A. and Henderson, Ian R. (2021). Loss of YhcB results in dysregulation of coordinated peptidoglycan, LPS and phospholipid synthesis during Escherichia coli cell growth. PLoS Genetics, 17 (12) e1009586, 1-40. doi: 10.1371/journal.pgen.1009586
Lo, Harriet P., Lim, Ye-Wheen, Xiong, Zherui, Martel, Nick, Ferguson, Charles, Ariotti, Nicholas, Giacomotto, Jean, Rae, James, Floetenmeyer, Matthias, Moradi, Shayli Varasteh, Gao, Ya, Tillu, Vikas A., Xia, Di, Wang, Huang, Rahnama, Samira, Nixon, Susan J., Bastiani, Michele, Day, Ryan D., Smith, Kelly A., Palpant, Nathan J., Johnston, Wayne A., Alexandrov, Kirill, Collins, Brett M., Hall, Thomas E. and Parton, Robert G. (2021). Cavin4 interacts with Bin1 to promote T-tubule formation and stability in developing skeletal muscle. Journal of Cell Biology, 220 (12) e201905065. doi: 10.1083/jcb.201905065
Moreno-Layseca, Paulina, Jäntti, Niklas Z., Godbole, Rashmi, Sommer, Christian, Jacquemet, Guillaume, Al-Akhrass, Hussein, Conway, James R. W., Kronqvist, Pauliina, Kallionpää, Roosa E., Oliveira-Ferrer, Leticia, Cervero, Pasquale, Linder, Stefan, Aepfelbacher, Martin, Zauber, Henrik, Rae, James, Parton, Robert G., Disanza, Andrea, Scita, Giorgio, Mayor, Satyajit, Selbach, Matthias, Veltel, Stefan and Ivaska, Johanna (2021). Cargo-specific recruitment in clathrin- and dynamin-independent endocytosis. Nature Cell Biology, 23 (10), 1073-1084. doi: 10.1038/s41556-021-00767-x
Kadir, Shereen R, Lilja, Andrew, Gunn, Nick, Strong, Campbell, Hughes, Rowan T, Bailey, Benjamin J, Rae, James, Parton, Robert G and McGhee, John (2021). Nanoscape, a data-driven 3D real-time interactive virtual cell environment. eLife, 10 e64047, 1-36. doi: 10.7554/elife.64047
Sun, Xuan, Cao, Benjamin, Naval-Sanchez, Marina, Pham, Tony, Sun, Yu Bo Yang, Williams, Brenda, Heazlewood, Shen Y, Deshpande, Nikita, Li, Jinhua, Kraus, Felix, Rae, James, Nguyen, Quan, Yari, Hamed, Schröder, Jan, Heazlewood, Chad K, Fulton, Madeline, Hatwell-Humble, Jessica, Das Gupta, Kaustav, Kapetanovic, Ronan, Chen, Xiaoli, Sweet, Matthew J, Parton, Robert G, Ryan, Michael T, Polo, Jose M, Nefzger, Christian M and Nilsson, Susan K (2021). Nicotinamide riboside attenuates age-associated metabolic and functional changes in hematopoietic stem cells. Nature Communications, 12 (1) 2665, 1-17. doi: 10.1038/s41467-021-22863-0
Rae, James, Ferguson, Charles, Ariotti, Nicholas, Webb, Richard I., Cheng, Han-Hao, Mead, James L., Riches, James D., Hunter, Dominic J.B., Martel, Nick, Baltos, Joanne, Christopoulos, Arthur, Bryce, Nicole S., Cagigas, Maria Lastra, Fonseka, Sachini, Sayre, Marcel E., Hardeman, Edna C., Gunning, Peter W., Gambin, Yann, Hall, Thomas E. and Parton, Robert G. (2021). A robust method for particulate detection of a genetic tag for 3D electron microscopy. eLife, 10 e64630, 1-17. doi: 10.7554/eLife.64630
Tillu, Vikas A., Rae, James, Gao, Ya, Ariotti, Nicholas, Floetenmeyer, Matthias, Kovtun, Oleksiy, McMahon, Kerrie-Ann, Chaudhary, Natasha, Parton, Robert G. and Collins, Brett M. (2021). Cavin1 intrinsically disordered domains are essential for fuzzy electrostatic interactions and caveola formation. Nature Communications, 12 (1) 931, 931. doi: 10.1038/s41467-021-21035-4
Zhou, Yong, Ariotti, Nicholas, Rae, James, Liang, Hong, Tillu, Vikas, Tee, Shern, Bastiani, Michele, Bademosi, Adekunle T., Collins, Brett M., Meunier, Frederic A., Hancock, John F. and Parton, Robert G. (2021). Caveolin-1 and cavin1 act synergistically to generate a unique lipid environment in caveolae. Journal of Cell Biology, 220 (3) e202005138. doi: 10.1083/jcb.202005138
Gormal, Rachel S., Padmanabhan, Pranesh, Kasula, Ravikiran, Bademosi, Adekunle T., Coakley, Sean, Giacomotto, Jean, Blum, Ailisa, Joensuu, Merja, Wallis, Tristan P., Lo, Harriet P., Budnar, Srikanth, Rae, James, Ferguson, Charles, Bastiani, Michele, Thomas, Walter G., Pardon, Els, Steyaert, Jan, Yap, Alpha S., Goodhill, Geoffrey J., Hilliard, Massimo A., Parton, Robert G. and Meunier, Frédéric A. (2020). Modular transient nanoclustering of activated β2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodies. Proceedings of the National Academy of Sciences of the United States of America, 117 (48), 30476-30487. doi: 10.1073/pnas.2007443117
Ariotti, Nicholas, Wu, Yeping, Okano, Satomi, Gambin, Yann, Follett, Jordan, Rae, James, Ferguson, Charles, Teasdale, Rohan D., Alexandrov, Kirill, Meunier, Frederic A., Hill, Michelle M. and Parton, Robert G. (2020). An inverted CAV1 (caveolin 1) topology defines novel autophagy-dependent exosome secretion from prostate cancer cells. Autophagy, 17 (9), 1-17. doi: 10.1080/15548627.2020.1820787
Hall, Thomas E., Martel, Nick, Ariotti, Nicholas, Xiong, Zherui, Lo, Harriet P., Ferguson, Charles, Rae, James, Lim, Ye-Wheen and Parton, Robert G. (2020). In vivo cell biological screening identifies an endocytic capture mechanism for T-tubule formation. Nature Communications, 11 (1) 3711, 3711. doi: 10.1038/s41467-020-17486-w
Stocks, Claudia J., Pein, Jessica B., Curson, James E.B., Rae, James, Phan, Minh‐Duy, Foo, Darren, Bokil, Nilesh J., Kambe, Taiho, Peters, Kate M., Parton, Robert G., Schembri, Mark A., Kapetanovic, Ronan and Sweet, Matthew J. (2020). Frontline Science: LPS‐inducible SLC30A1 drives human macrophage‐mediated zinc toxicity against intracellular Escherichia coli. Journal of Leukocyte Biology, 109 (2) JLB.2HI0420-160R, 287-297. doi: 10.1002/jlb.2hi0420-160r
Bywater, Megan J., Burkhart, Deborah L., Straube, Jasmin, Sabò, Arianna, Pendino, Vera, Hudson, James E., Quaife-Ryan, Gregory A., Porrello, Enzo R., Rae, James, Parton, Robert G., Kress, Theresia R., Amati, Bruno, Littlewood, Trevor D., Evan, Gerard I. and Wilson, Catherine H. (2020). Reactivation of Myc transcription in the mouse heart unlocks its proliferative capacity. Nature Communications, 11 (1) 1827, 1827. doi: 10.1038/s41467-020-15552-x
Chew, Hui Yi, De Lima, Priscila O., Gonzalez Cruz, Jazmina L., Banushi, Blerida, Echejoh, Godwins, Hu, Lingbo, Joseph, Shannon R., Lum, Benedict, Rae, James, O'Donnell, Jake S., Merida de Long, Lilia, Okano, Satomi, King, Brigid, Barry, Rachael, Moi, Davide, Mazzieri, Roberta, Thomas, Ranjeny, Souza-Fonseca-Guimaraes, Fernando, Foote, Matthew, McCluskey, Adam, Robinson, Phillip J., Frazer, Ian H., Saunders, Nicholas A., Parton, Robert G., Dolcetti, Riccardo, Cuff, Katharine, Martin, Jennifer H., Panizza, Benedict, Walpole, Euan ... Simpson, Fiona (2020). Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies. Cell, 180 (5), 895-914.e27. doi: 10.1016/j.cell.2020.02.019
Bhattachan, Punit, Rae, James, Yu, Haiyan, Jung, WooRam, Wei, Jiankai, Parton, Robert G. and Dong, Bo (2020). Ascidian caveolin induces membrane curvature and protects tissue integrity and morphology during embryogenesis. The FASEB Journal, 34 (1), 1345-1361. doi: 10.1096/fj.201901281R
Du, Ximing, Zhou, Linkang, Aw, Yvette Celine, Mak, Hoi Yin, Xu, Yanqing, Rae, James, Wang, Wenmin, Zadoorian, Armella, Hancock, Sarah E., Osborne, Brenna, Chen, Xiang, Wu, Jia-Wei, Turner, Nigel, Parton, Robert G., Li, Peng and Yang, Hongyuan (2020). ORP5 localizes to ER–lipid droplet contacts and regulates the level of PI(4)P on lipid droplets. The Journal of Cell Biology, 219 (1) jcb.201905162. doi: 10.1083/jcb.201905162
Wang, Huan, Ma, Qianli, Qi, Yanfei, Dong, Jiangqing, Du, Ximing, Rae, James, Wang, Jue, Wu, Wei-Feng, Brown, Andrew J., Parton, Robert G., Wu, Jia-Wei and Yang, Hongyuan (2019). ORP2 delivers cholesterol to the plasma membrane in exchange for phosphatidylinositol 4, 5-bisphosphate (PI(4,5)P2). Molecular Cell, 73 (3), 458-473. doi: 10.1016/j.molcel.2018.11.014
Hall, Thomas E., Rae, James, Ariotti, Nicholas and Parton, Robert G. (2018). Electron microscopic detection of proteins and protein complexes in mammalian cells using APEX-tagged, conditionally stable nanobodies. Bio-Protocol, 8 (22), e3088. doi: 10.21769/BioProtoc.3088
Sathe, Mugdha, Muthukrishnan, Gayatri, Rae, James, Disanza, Andrea, Thattai, Mukund, Scita, Giorgio, Parton, Robert G and Mayor, Satyajit (2018). Small GTPases and BAR domain proteins regulate branched actin polymerisation for clathrin and dynamin-independent endocytosis. Nature Communications, 9 (1) 1835, 1835. doi: 10.1038/s41467-018-03955-w
Jung, WooRam, Sierecki, Emma, Bastiani, Michele, O'Carroll, Ailis, Alexandrov, Kirill, Rae, James, Johnston, Wayne, Hunter, Dominic J. B., Ferguson, Charles, Gambin, Yann, Ariotti, Nicholas and Parton, Robert G. (2018). Cell-free formation and interactome analysis of caveolae. The Journal of Cell Biology, 217 (6), 2141-2165. doi: 10.1083/jcb.201707004
Ariotti, Nicholas, Rae, James, Giles, Nichole, Martel, Nick, Sierecki, Emma, Gambin, Yann, Hall, Thomas E. and Parton, Robert G. (2018). Ultrastructural localisation of protein interactions using conditionally stable nanobodies. PLoS Biology, 16 (4) e2005473, e2005473. doi: 10.1371/journal.pbio.2005473
Johnston, Angus P. R., Rae, James, Ariotti, Nicholas, Bailey, Benjamin, Lija, Andrew, Webb, Robyn, Ferguson, Charles, Maher, Sheryl, Davis, Thomas P., Webb, Richard I., McGhee, John and Parton, Robert G. (2017). Journey to the centre of the cell: Virtual reality immersion into scientific data. Traffic (Copenhagen, Denmark), 19 (2), 105-110. doi: 10.1111/tra.12538
Glass, Joshua J., Yuen, Daniel, Rae, James, Johnston, Angus P. R., Parton, Robert G., Kent, Stephen J. and De Rose, Robert (2016). Human immune cell targeting of protein nanoparticles-caveospheres. Nanoscale, 8 (15), 8255-8265. doi: 10.1039/c6nr00506c
Ariotti, Nicholas, Hall, Thomas, Rae, James, Ferguson, Charles, McMahon, Kerrie-Ann, Martel, Nick, Webb, Robyn E., Webb, Richard I., Teasdale, Rohan D. and Parton, Robert G. (2015). Modular detection of GFP-labeled proteins for rapid screening by electron microscopy in cells and organisms. Developmental Cell, 35 (4), 513-525. doi: 10.1016/j.devcel.2015.10.016
Ariotti, Nicholas, Rae, James, Leneva, Natalya, Ferguson, Charles, Loo, Dorothy, Okano, Satomi, Hill, Michelle M., Walser, Piers, Collins, Brett M. and Parton, Robert G. (2015). Molecular characterization of caveolin-induced membrane curvature. Journal of Biological Chemistry, 290 (41), 24875-24890. doi: 10.1074/jbc.M115.644336
Inder, Kerry L., Ruelcke, Jayde E., Petelin, Lara, Moon, Hyeongsun, Choi, Eunju, Rae, James, Blumenthal, Antje, Hutmacher, Dietmar, Saunders, Nicholas A., Stow, Jennifer L., Parton, Robert G. and Hill, Michelle M. (2014). Cavin-1/PTRF alters prostate cancer cell-derived extracellular vesicle content and internalization to attenuate extracellular vesicle-mediated osteoclastogenesis and osteoblast proliferation. Journal of Extracellular Vesicles, 3 (1) 23784, 23784.1-23784.14. doi: 10.3402/jev.v3.23784
Chaudhary, Natasha, Gomez, Guillermo A., Howes, Mark T., Lo, Harriet P., McMahon, Kerrie-Ann, Rae, James A., Schieber, Nicole L., Hill, Michelle M., Gaus, Katharina, Yap, Alpha S. and Parton, Robert G. (2014). Endocytic Crosstalk: Cavins, Caveolins, and Caveolae Regulate Clathrin-Independent Endocytosis. PLoS Biology, 12 (4) e1001832, e1001832.1-e1001832.20. doi: 10.1371/journal.pbio.1001832
Walser, Piers, Ariotti, Nicholas, Howes, Mark, Ferguson, Charles, Webb, Richard, Schwudke, Dominik, Leneva, Natalya, Cho, Kwang-Jin, Cooper, Leanne, Rae, James, Floetenmeyer, Matthias, Oorschot, Viola M. J., Skoglund, Ulf, Simons, Kai, Hancock, John F. and Parton, Robert G. (2012). Constitutive formation of caveolae in a bacterium. Cell, 150 (4), 752-763. doi: 10.1016/j.cell.2012.06.042
Rae, James, Fontaine, Frank, Salim, Angela A., Lo, Harriet P., Capon, Robert J., Parton, Robert G. and Martin, Sally (2011). High-throughput screening of Australian marine organism extracts for bioactive molecules affecting the cellular storage of neutral lipids. PLoS One, 6 (8) e22868, e22868.1-e22868.13. doi: 10.1371/journal.pone.0022868
Salim, Angela A., Rae, James, Fontaine, Frank, Conte, Melissa M., Khalil, Zeinab, Martin, Sally, Parton, Robert G. and Capon, Robert J. (2010). Heterofibrins: Inhibitors of lipid droplet formation from a deep-water southern Australian marine sponge, Spongia (Heterofibria) sp.. Organic and Biomolecular Chemistry, 8 (14), 3188-3194. doi: 10.1039/c003840g