Dr Carol Wicking

Gual-Soler, Marga, Taguchi, Tomohiko, Stow, Jennifer L. and Wicking, Carol (2012). Rab23. Encyclopedia of signalling molecules. (pp. 1532-1536) edited by Sangdun Choi. New York, United States: Springer. doi: 10.1007/978-1-4419-0461-4

Wicking, C. A. and Evans, T. (2006). Hedgehog signalling. Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine. (pp. 749-752) edited by Ganten, Detlev and Ruckpaul, Klaus. Berlin, Heidelberg, New York: Springer. doi: 10.1007/3-540-29623-9_4290

Evans, Timothy M., Simpson, Fiona, Parton, Robert G. and Wicking, Carol (2005). Characterization of Rab23, a negative regulator of sonic hedgehog signaling. GTPases regulating membrane targeting and fusion. (pp. 759-777) edited by William E. Balch, Channing J. Der and Alan Hall. Maryland Heights, MO, United States: Academic Press. doi: 10.1016/S0076-6879(05)03066-1

Mcinerney-Leo, Aideen M., Wheeler, Lawrie, Marshall, Mhairi S., Anderson, Lisa K., Zankl, Andreas, Brown, Matthew A., Leo, Paul J., Wicking, Carol and Duncan, Emma L. (2017). Homozygous variant in C21orf2 in a case of Jeune syndrome with severe thoracic involvement: extending the phenotypic spectrum. American Journal of Medical Genetics, 173 (6), 1698-1704. doi: 10.1002/ajmg.a.38215

De Angelis, Jessica E., Lagendijk, Anne K., Chen, Huijun, Tromp, Alisha, Bower, Neil I., Tunny, Kathryn A., Brooks, Andrew J., Bakkers, Jeroen, Francois, Mathias, Yap, Alpha S., Simons, Cas, Wicking, Carol, Hogan, Benjamin M. and Smith, Kelly A. (2017). Correction to: Tmem2 regulates embryonic Vegf signaling by controlling hyaluronic acid turnover (Developmental Cell 40, 2017, 123-136). Developmental Cell, 40 (4), 421-421. doi: 10.1016/j.devcel.2017.02.005

De Angelis, Jessica E., Lagendijk, Anne K., Chen, Huijun, Tromp, Alisha, Bower, Neil I., Tunny, Kathryn A., Brooks, Andrew J., Bakkers, Jeroen, Francois, Mathias, Yap, Alpha S., Simons, Cas, Wicking, Carol, Hogan, Benjamin M. and Smith, Kelly A. (2017). Tmem2 regulates embryonic Vegf signaling by controlling hyaluronic acid turnover. Developmental Cell, 40 (2), 123-136. doi: 10.1016/j.devcel.2016.12.017

Dyson, Jennifer M., Conduit, Sarah E., Feeney, Sandra J., Hakim, Sandra, DiTommaso, Tia, Fulcher, Alex J., Sriratana, Absorn, Ramm, Georg, Horan, Kristy A., Gurung, Rajendra, Wicking, Carol, Smyth, Ian and Mitchell, Christina A. (2017). INPP5E regulates phosphoinositide-dependent cilia transition zone function. The Journal of Cell Biology, 216 (1), 247-263. doi: 10.1083/jcb.201511055

Mcinerney-Leo, Aideen M., Harris, Jessica E., Gattas, Michael, Peach, Elizabeth E., Sinnott, Stephen, Dudding-Byth, Tracy, Rajagopalan, Sulekha, Barnett, Christopher, Anderson, Lisa K., Wheeler, Lawrie, Brown, Matthew A., Leo, Paul J., Wicking, Carol and Duncan, Emma L. (2016). Fryns syndrome associated with recessive mutations in PIGN in two separate families. Human Mutation, 37 (7), 695-702. doi: 10.1002/humu.22994

Cortes, Claudio R., McInerney-Leo, Aideen M., Vogel, Ida, Rondon Galeano, Maria C., Leo, Paul J., Harris, Jessica E., Anderson, Lisa K., Keith, Patricia A., Brown, Matthew A., Ramsing, Mette, Duncan, Emma L., Zankl, Andreas and Wicking, Carol (2016). Mutations in human C2CD3 cause skeletal dysplasia and provide new insights into phenotypic and cellular consequences of altered C2CD3 function. Scientific Reports, 6 (1) 24083, 24083. doi: 10.1038/srep24083

Cortes, Claudio R., Metzis, Vicki and Wicking, Carol (2015). Unmasking the ciliopathies: Craniofacial defects and the primary cilium. Wiley Interdisciplinary Reviews: Developmental Biology, 4 (6), 637-653. doi: 10.1002/wdev.199

McInerney-Leo, Aideen, Harris, Jessica E., Leo, Paul, Marshall, Mhairi, Gardiner, Brooke, Kinning, Esther, Leong, Huey Yin, McKenzie, Fiona, Ong, PeiTee, Vodopiutz, Julia, Wicking, Carol A., Brown, Matthew A., Zanki, Andreas and Duncan, Emma (2015). Whole exome sequencing is an efficient, sensitive and specific method for determining the genetic cause of short-rib thoracic dystrophies. Clinical Genetics, 88 (6), 550-557. doi: 10.1111/cge.12550

Wainwright, Elanor N., Svingen, Terje, Ng, Ee Ting, Wicking, Carol and Koopman, Peter (2014). Primary cilia function regulates the length of the embryonic trunk axis and urogenital field in mice. Developmental Biology, 395 (2), 342-354. doi: 10.1016/j.ydbio.2014.08.037

Lopez-Rios, Javier, Duchesne, Amandine, Speziale, Dario, Peterson, Kevin A., Germann, Philipp, Unal, Erkan, Liu, Jing, Floriot, Sandrine, Barbey, Sarah, Gallard, Yves, Muller-Gerbl, Magdalena, Courtney, Andrew D., Klopp, Christophe, Rodriguez, Sabrina, Ivanek, Robert, Beisel, Christian, Wicking, Carol, Iber, Dagmar, Robert, Benoit, McMahon, Andrew P., Duboule, Denis and Zeller, Rolf (2014). Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs. Nature, 511 (7507), 46-51. doi: 10.1038/nature13289

Schmidts, Miriam, Vodopiutz, Julia, Christou-Savina, Sonia, Cortés, Claudio R., McInerney-Leo, Aideen M., Emes, Richard D., Arts, Heleen H., Tüysüz, Beyhan, D'Silva, Jason, Leo, Paul J., Giles, Tom C., Oud, Machteld M., Harris, Jessica A., Koopmans, Marije, Marshall, Mhairi, Elçioglu, Nursel, Kuechler, Alma, Bockenhauer, Detlef, Moore, Anthony T., Wilson, Louise C., Janecke, Andreas R., Hurles, Matthew E., Emmet, Warren, Gardiner, Brooke, Streubel, Berthold, Dopita, Belinda, Zankl, Andreas, Kayserili, Hülya, Scambler, Peter J. ... Mitchison, Hannah M. (2013). Mutations in the gene encoding IFT dynein complex component WDR34 cause Jeune asphyxiating thoracic dystrophy. American Journal of Human Genetics, 93 (5), 932-944. doi: 10.1016/j.ajhg.2013.10.003

McInerney-Leo, Aideen M., Schmidts, Miriam, Cortés, Claudio R., Leo, Paul J., Gener, Blanca, Courtney, Andrew D., Gardiner, Brooke, Harris, Jessica A., Lu, Yeping, Marshall, Mhairi, Scrambler, Peter J., Beales, Philip L., Brown, Matthew A., Zankl, Andreas, Mitchison, Hannah M., Duncan, Emma L., Wicking, Carol and UK10K Consortium (2013). Short-rib polydactyly and Jeune Syndromes are caused by mutations in WDR60. American Journal of Human Genetics, 93 (3), 515-523. doi: 10.1016/j.ajhg.2013.06.022

Metzis, Vicki, Courtney, Andrew D., Kerr, Markus C., Ferguson, Charles, Rondón Galeano, Maria C., Parton, Robert G., Wainwright, Brandon J. and Wicking, Carol (2013). Patched1 is required in neural crest cells for the prevention of orofacial clefts. Human Molecular Genetics, Advance Access (24) ddt353, 1-10. doi: 10.1093/hmg/ddt353

Shi, Wei, Bain, Amanda L., Schwer, Bjoern, Al-Ejeh, Fares, Smith, Corey, Wong, Lee, Chai, Hua, Miranda, Mariska S., Ho, Uda, Kawaguchi, Makoto, Miura, Yutaka, Finnie, John W., Wall, Meaghan, Heierhorst, Jorg, Wicking, Carol, Spring, Kevin J., Alt, Frederick W. and Khanna, Kum Kum (2013). Essential developmental, genomic stability, and tumour suppressor functions of the mouse orthologue of hSSB1/NABP2. PLoS Genetics, 9 (2) e1003298, e1003298.1-e1003298.19. doi: 10.1371/journal.pgen.1003298

Wade, Christine, Brinas, Inigo, Welfare, Megan, Wicking, Carol and Farlie, Peter G. (2012). Twist2 contributes to termination of limb bud outgrowth and patterning through direct regulation of Grem1. Developmental Biology, 370 (1), 145-153. doi: 10.1016/j.ydbio.2012.07.025

Liu, Fan, van der Lijn, Fedde, Schurmann, Claudia, Zhu, Gu, Chakravarty, M. Mallar, Hysi, Pirro G., Wollstein, Andreas, Lao, Oscar, de Bruijne, Marleen, Ikram, M. Arfan, van der Lugt, Aad, Rivadeneira, Fernando, Uitterlinden, Andre G., Hofman, Albert, Niessen, Wiro J., Homuth, Georg, de Zubicaray, Greig, McMahon, Katie L., Thompson, Paul M., Daboul, Amro, Puls, Ralf, Hegenscheid, Katrin, Bevan, Liisa, Pausova, Zdenka, Medland, Sarah E., Montgomery, Grant W., Wright, Margaret J., Wicking, Carol A., Boehringer, Stefan ... Kayser, Manfred for the International Visible Trait Genetics (VisiGen) Consortium (2012). A Genome-Wide Association Study Identifies Five Loci Influencing Facial Morphology in Europeans. PLoS Genetics, 8 (9) e1002932, e1002932.1-e1002932.13. doi: 10.1371/journal.pgen.1002932

Liem Jr., Karel F., Ashe, Alyson, He, Mu, Satir, Peter, Moran, Jennifer, Beier, David, Wicking, Carol and Anderson, Kathryn V. (2012). The IFT-A complex regulates Shh signaling through cilia structure and membrane protein trafficking. Journal of Cell Biology, 197 (6), 789-800. doi: 10.1083/jcb.201110049

Ashe, Alyson, Butterfield, Natalie C., Town, Liam, Courtney, Andrew D., Cooper, Ashley N., Ferguson, Charles, Barry, Rachael, Olsson, Fredrik, Liem, Karel F., Parton, Robert G., Wainwright, Brandon J., Anderson, Kathryn V., Whitelaw, Emma and Wicking, Carol (2012). Mutations in mouse Ift144 model the craniofacial, limb and rib defects in skeletal ciliopathies. Human Molecular Genetics, 21 (8) ddr613, 1808-1823. doi: 10.1093/hmg/ddr613

Smith, Kelly A., Lagendijk, Anne K., Courtney, Andrew D., Chen, Huijun, Paterson, Scott, Hogan, Benjamin M., Wicking, Carol and Bakkers, Jeroen (2011). Transmembrane protein 2 (Tmem2) is required to regionally restrict atrioventricular canal boundary and endocardial cushion development. Development, 138 (19), 4193-4198. doi: 10.1242/dev.065375

Town, Liam, McGlinn, Edwina, Davidson, Tara-Lynne, Browne, Catherine M., Chawengsaksophak, Kallayanee, Koopman, Peter, Richman, Joy M. and Wicking, Carol (2011). Tmem26 is dynamically expressed during palate and limb development but is not required for embryonic survival. PLoS One, 6 (9) e25228, e25228-1-e25228-9. doi: 10.1371/journal.pone.0025228

Wicking, Carol (2010). Embryos direct the traffic. Traffic, 11 (10), 1263-1264. doi: 10.1111/j.1600-0854.2010.01105.x

Bruce, Stephen J., Butterfield, Natalie C., Metzis, Vicki, Town, Liam, McGlinn, Edwina and Wicking, Carol (2010). Inactivation of Patched1 in the mouse limb has novel inhibitory effects on the chondrogenic program. Journal of Biological Chemistry, 285 (36), 27967-27981. doi: 10.1074/jbc.M109.091785

Johanson, Helene C., Chen, Wei, Wicking, Carol and Sturm, Richard A. (2010). Inheritance of a novel mutated allele of the OCA2 gene associated with high incidence of oculocutaneous albinism in a Polynesian community. Journal of Human Genetics, 55 (2), 103-111. doi: 10.1038/jhg.2009.130

Butterfield, Natalie C., McGlinn, Edwina and Wicking, Carol (2010). The molecular regulation of vertebrate limb patterning. Current Topics in Developmental Biology, 90 (C), 319-341. doi: 10.1016/S0070-2153(10)90009-4

Town, Liam, McGlinn, Edwina, Fiorenza, Salvatore, Metzis, Vicki, Butterfield, Natalie C., Richman, Joy M. and Wicking, Carol (2009). The metalloendopeptidase gene Pitrm1 is regulated by hedgehog signaling in the developing mouse limb and is expressed in muscle progenitors. Developmental Dynamics, 238 (12), 3175-3184. doi: 10.1002/dvdy.22126

Butterfield, N. C., Metzis, V, McGlinn, E, Bruce, S. J., Wainwright, B. J. and Wicking, C (2009). Patched 1 is a crucial determinant of asymmetry and digit number in the vertebrate limb. DEVELOPMENT, 136 (20), 3515-3524. doi: 10.1242/dev.037507

Simpson, Fiona, Kerr, Markus C. and Wicking, Carol (2009). Trafficking, development and hedgehog. Mechanisms of Development, 126 (5 - 6), 279-288. doi: 10.1016/j.mod.2009.01.007

Turchi, L., Fareh, M., Aberdam, E., Kitajima, S., Simpson, F, Wicking, C., Aberdam, D. and Virolle, T. (2009). ATF3 and p15(PAF) are novel gatekeepers of genomic integrity upon UV stress. Cell Death and Differentiation, 16 (5), 728-737. doi: 10.1038/cdd.2009.2

Johanson, H. C., Hyland, V, Wicking, C. A. and Sturm, R. A. (2009). DNA elution from buccal cells stored on Whatman FTA classic cards using a modified methanol fixation method. Bio Techniques, 46 (4), 309-311. doi: 10.2144/000113077

Ashe, Alyson, Morgan, Daniel K., Whitelaw, Nadia, Bruxner, Timothy J., Vickaryous, Nicola K., Cox, Liza L., Butterfield, Natalie C., Wicking, Carol, Blewitt, Marnie E., Wilkins, Sarah J., Anderson, Gregory J., Cox, Timothy C. and Whitelaw, Emma (2008). A genome-wide screen for modifiers of transgene variegation identifies genes with critical roles in development. Genome Biology, 9 (12) R182, R182-1-R182-16. doi: 10.1186/gb-2008-9-12-r182

McGlinn, Edwina, Richman, Joy M., Metzis, Vicki, Town, Liam, Butterfield, Natalie C., Wainwright, Brandon J. and Wicking, Carol (2008). Expression of the NET family member Zfp503 is regulated by hedgehog and BMP signaling in the limb. Developmental Dynamics, 237 (4), 1172-1182. doi: 10.1002/dvdy.21508

Buchtova, M., Handrigan, G. R., Tucker, A. S., Lozanoff, S., Town, L., Fu, K., Diewert, V. M., Wicking, C. and Richman, J. M. (2008). Initiation and patterning of the snake dentition are dependent on Sonic Hedgehog signaling. Developmental Biology, 319 (1), 132-145. doi: 10.1016/j.ydbio.2008.03.004

Bennetts, Jennifer S., Rendtorff, Nanna D., Simpson, Fiona, Tranebjaerg, Lisbeth and Wicking, Carol (2007). The coding region of TP53INP2, a gene expressed in the developing nervous system, is not altered in a family with autosomal recessive non-progressive infantile ataxia on chromosome 20q11-q13. Developmental Dynamics, 236 (3), 843-852. doi: 10.1002/dvdy.21064

Lammerts van Bueren, Kelly, Bennetts, Jennifer S., Fowles, Lindsay F., Berkman, Jennifer L., Simpson, Fiona and Wicking, Carol (2007). Murine embryonic expression of the gene for the UV-responsive protein p15(PAF). Gene Expression Patterns, 7 (1-2), 47-50. doi: 10.1016/j.modgep.2006.05.006

Bennetts, Jennifer S., Fowles, Lindsay F., Berkman, Jennifer L., Lammerts van Bueren, Kelly, Richman, Joy M., Simpson, Fiona and Wicking, Carol (2006). Evolutionary conservation and murine embryonic expression of the gene encoding the SERTA domain-containing protein CDCA4 (HEPP). Gene, 374 (1-2), 153-165. doi: 10.1016/j.gene.2006.01.027

Hollway, G. E., Maule, J., Gautier, P., Evans, T. M., Keenan, D. G., Lohs, C., Fischer, D., Wicking, C. and Currie, P. D. (2006). Scube2 mediates Hedgehog signalling in the zebrafish embryo. Developmental Biology, 294 (1), 104-118. doi: 10.1016/j.ydbio.2006.02.032

Bennetts, Jennifer S., Fowles, Lindsay F., Butterfield, Natalie C., Berkman, Jennifer L., Teasdale, Rohan D., Simpson, Fiona and Wicking, Carol (2006). Identification and analysis of novel genes expressed in the mouse embryonic facial primordia. Frontiers In Bioscience, 11 (SUPPL. 2), 2631-2646. doi: 10.2741/1997

Simpson, Fiona, Lammerts van Bueren, Kelly L., Butterfield, Natalie, Bennetts, Jennifer S., Bowles, Josephine, Adolphe, Christelle, Simms, Lisa A., Young, Joanne, Walsh, Michael D., Leggett, Barbara, Fowles, Lindsay F. and Wicking, Carol (2006). The PCNA-associated factor KIAA0101/p15(PAF) binds the potential tumor suppressor product p33ING1b. Experimental Cell Research, 312 (1), 73-85. doi: 10.1016/j.yexcr.2005.09.020

McGlinn, Edwina, Lammerts van Bueren, Kelly, Fiorenza, Salvatore, Mo, Rong, Poh, Alisa M., Forrest, Alistair, Soares, Marcelo Bento, Bonaldo, Maria de Fatima, Grimmond, Sean, Hui, Chi-chung, Wainwright, Brandon and Wicking, Carol (2005). Pax9 and Jagged1 act downstream of Gli3 in vertabrate limb development. Mechanisms of Development, 122 (11), 1218-1233. doi: 10.1016/j.mod.2005.06.012

Kerr, Markus C., Bennetts, Jennifer S., Simpson, Fiona, Thomas, Elaine C., Flegg, Cameron, Gleeson, Paul A., Wicking, Carol and Teasdale, Rohan D. (2005). A Novel Mammalian Retromer Component, Vps26B. Traffic, 6 (11), 991-1001. doi: 10.1111/j.1600-0854.2005.00328.x

Marsh, A., Wicking, C. A., Wainwright, B. J. and Chenevix-Trench, G. (2005). DHPLC analysis of patients with nevoid basal cell carcinoma syndrome reveals novel PTCH missense mutations in the serol-sensing domain. Human Mutation, 26 (3) ARTN 836, 283-293. doi: 10.1002/humu.9365

Simpson, Fiona, Martin, Sally, Evans, Timothy M., Kerr, Markus, James, David E., Parton, Robert G., Teasdale, Rohan D. and Wicking, Carol (2005). A novel hook-related protein family and the characterization of Hook-related protein 1. Traffic, 6 (6), 442-458. doi: 10.1111/j.1600-0854.2005.00289.x

Hime, G. R., Lada, H., Fietz, M. J., Gillies, S., Passmore, A., Wicking, C. A. and Wainwright, B. J. (2004). Functional analysis in Drosophila indicates that the NBCCS/PTCH1 mutation G509V results in activation of smoothened through a dominant-negative mechanism. Developmental Dynamics, 229 (4), 780-790. doi: 10.1002/dvdy.10499

Adolphe, C., Narang, M., Ellis, T., Wicking, C., Kaur, P. and Wainwright, B. (2004). An in vivo comparative study of sonic, desert and Indian hedgehog reveals that hedgehog pathway activity regulates epidermal stem cell homeostasis. Development, 131 (20), 5009-5019. doi: 10.1242/dev.01367

Smyth, Ian, Ellis, Tammy, Hetherington, Rehan, Riley, Emily, Narang, Monica, Mahony, Donna, Wicking, Carol, Rothnagel, Joseph A. and Wainwright, Brandon J. (2004). Krt6a-Cre transgenic mice direct LoxP-mediated recombination to the companion cell layer of the hair follicle and following induction by retinoic acid to the interfollicular epidermis. Journal of Investigative Dermatology, 122 (1), 232-234. doi: 10.1046/j.0022-202X.2003.22122.x

Lalonde, Jean-Philippe, Lim, Raelene, Ingley, Evan, Tilbrook, Peta A., Thompson, Martin J., McCulloch, Ross, Beaumont, Jennifer G., Wicking, Carol, Eyre, Helen J., Sutherland, Grant R., Howe, Kathy, Solomon, Ellen, Williams, James H. and Klinken, S. Peter (2004). HLS5, a novel RBCC (ring finger, B box, coiled-coil) family member isolated from a hemopoietic lineage switch, is a candidate tumor suppressor. Journal of Biological Chemistry, 279 (9), 8181-8189. doi: 10.1074/jbc.M306751200

Ellis, Tammy, Smyth, Ian, Riley, Emily, Graham, Scott, Elliot, Kate, Narang, Monica, Kay, Graham F., Wicking, Carol and Wainwright, Brandon (2003). Patched 1 conditional null allele in mice. Genesis, 36 (3), 158-161. doi: 10.1002/gene.10208

Ellis, Tammy, Smyth, Ian, Riley, Emily, Bowles, Josephine, Adolphe, Christelle, Rothnagel, Joseph A., Wicking, Carol and Wainwright, Brandon J. (2003). Overexpression of sonic hedgehog suppresses embryonic hair follicle morphogenesis. Developmental Biology, 263 (2), 203-215. doi: 10.1016/S0012-1606(03)00394-4

Evans, T. M., Ferguson, C., Wainwright, B. J., Parton, R. G. and Wicking, C. (2003). Rab23, a negative regulator of hedgehog signaling, localizes to the plasma membrane and the endocytic pathway. Traffic, 4 (12), 869-884. doi: 10.1046/j.1600-0854.2003.00141.x

Fowles, L. F., Bennetts, J. S., Berkman, J. L., Williams, E., Koopman, P., Teasdale, R. D. and Wicking, C. (2003). Genomic screen for genes involved in mammalian craniofacial development. Genesis, 35 (2), 73-87. doi: 10.1002/gene.10165

Ingram, W. J., Wicking, C. A., Grimmond, S. M., Forrest, A. R. and Wainwright, B. J. (2002). Novel genes regulated by Sonic Hedgehog in pluripotent mesenchymal cells. Oncogene, 21 (53), 8196-8205. doi: 10.1038/sj.onc.1205975

Nawshad, A. I., Wicking, C. A. and Savage, N. W. (2002). Loss of heterozygosity and mutation analysis of PTCH gene in odontogenic keratocysts. Australian Dental Journal, 47 (4), S15-S16.

Evans, T, Poh, A, Webb, C, Wainwright, B, Wicking, C, Glass, I, Carey, WF and Fietz, M (2001). Novel mutation in the Delta 7-dehydrocholesterol reductase gene in an Australian patient with Smith-Lemli-Opitz syndrome. American Journal of Medical Genetics, 103 (4), 344-347. doi: 10.1002/ajmg.1573

Wicking, C. and McGlinn, E. (2001). The role of hedgehog signalling in tumorigenesis. Cancer Letters, 173 (1), 1-7. doi: 10.1016/S0304-3835(01)00676-0

Evans, T, Boonchai, W, Shanley, S, Smyth, I, Gillies, S, Georgas, K, Wainwright, B, Chenevix-Trench, G and Wicking, C (2000). The spectrum of patched mutations in a collection of Australian basal cell carcinomas. Human Mutation, 16 (1), 43-48. doi: 10.1002/1098-1004(200007)16:1<43::AID-HUMU8>3.0.CO;2-7

Wilson, PJ, McGlinn, E, Marsh, A, Evans, T, Arnold, J, Wright, K, Biden, K, Young, J, Wainwright, B, Wicking, C and Chenevix-Trench, G (2000). Sequence variants of DLC1 in colorectal ovarian tumours. Human Mutation, 15 (2), 156-165. doi: 10.1002/(SICI)1098-1004(200002)15:2

Simms, L. A., Young, J., Wicking, C., Meltzer, S. J., Jass, J. R. and Leggett, B. A. (2000). The apoptotic regulatory gene, BCL10, is mutated in sporadic mismatch repair deficient colorectal cancers. Cell Death & Differentiation, 7 (2), 236-237. doi: 10.1038/sj.cdd.4400650

Wicking, Carol, Smyth, Ian and Bale, Allen (1999). The hedgehog signalling pathway in tumorigenesis and development. Oncogene, 18 (55), 7844-7851. doi: 10.1038/sj.onc.1203282

Smyth, I, Bowles, J, Rothnagel, J, Wicking, C and Wainwright, B (1999). Ectopic expression of Sonic Hedgehog from the human Keratin 1 promoter gives rise to limb abnormalities and skin lesions in transgenic mice.. American Journal of Human Genetics, 65 (4), A371-A371.

Smyth, I., Narang, M. A., Evans, T. M., Heimann, C., Nakamura, Y., Chenevix-Trench, G., Pietsch, T., Wicking, C. A. and Wainwright, B. J. (1999). Isolation and characterization of human patched 2 (PTCH2), a putative tumour suppressor gene in basal cell carcinoma and medulloblastoma on chromosome 1p32. Human Molecular Genetics, 8 (2), 291-297. doi: 10.1093/hmg/8.2.291

Wicking, C., Smyth, I. and Bale, A. (1999). The hedgehog signalling pathway in tumorigenesis and development. Oncogene, 18 (55), 7844-7851.

Wicking, C, Simms, LA, Evans, T, Walsh, M, Chawengsaksophak, K, Beck, F, Chenevix-Trench, G, Young, J, Jass, J, Leggett, B and Wainwright, B (1998). CDX2, a human homologue of Drosophila caudal, is mutated in both alleles in a replication error positive colorectal cancer. Oncogene, 17 (5), 657-659. doi: 10.1038/sj.onc.1201971

Smyth, , Wicking, C, Wainwright, B and Chenevix-Trench, G (1998). The effects of splice site mutations in patients with naevoid basal cell carcinoma syndrome. Human Genetics, 102 (5), 598-601. doi: 10.1007/s004390050747

Wicking, C, Evans, T, Henk, B, Hayward, N, Simms, LA, Chenevix-Trench, G, Pietsch, T and Wainwright, B (1998). No evidence for the H133Y mutation in SONIC HEDGEHOG in a collection of common tumour types. Oncogene, 16 (8), 1091-1093. doi: 10.1038/sj.onc.1201644

Richards, Frances M., Goudie, David R., Cooper, Wendy N., Jene, Quitz, Barroso, Inês , Wicking, Carol, Wainwright, Brandon J. and Ferguson-Smith, Malcolm A. (1997). Mapping the multiple self-healing squamous epithelioma (MSSE) gene and investigation of xeroderma pigmentosum group A (XPA) and PATCHED (PTCH) as candidate genes. Human Genetics, 101 (3), 317-322. doi: 10.1007/s004390050635

Lench, NJ, Telford, EAR, High, AS, Markham, AF, Wicking, C and Wainwright, BJ (1997). Characterisation of human patched germ line mutations in naevoid basal cell carcinoma syndrome. Human Genetics, 100 (5-6), 497-502. doi: 10.1007/s004390050541

Pietsch, T, Waha, A, Koch, A, Kraus, J, Albrecht, S, Tonn, J, Sorensen, N, Berthold, F, Henk, B, Schmandt, N, Wolf, HK, vonDeimling, A, Wainwright, B, ChenevixTrench, G, Wiestler, OD and Wicking, C (1997). Medulloblastomas of the desmoplastic variant carry mutations of the human homologue of Drosophila patched. Cancer Research, 57 (11), 2085-2088.

Levanat, S, Chidambaram, A, Wicking, C, BrayWard, P, Pressman, C, Toftgard, R, Gailani, MR, Myers, JC, Wainwright, B, Dean, M and Bale, AE (1997). Pulsed-field gel electrophoresis and FISH mapping of chromosome 9q22: Placement of a novel zinc finger gene within the NBCCS and ESS1 region. Cytogenetics and Cell Genetics, 76 (3-4), 208-213. doi: 10.1159/000134551

Wicking, Carol and Bale, Allen E. (1997). Molecular basis of the nevoid basal cell carcinoma syndrome. Current Opinion in Pediatrics, 9 (6), 630-635. doi: 10.1097/00008480-199712000-00013

Wicking, Carol, Shanley, Susan, Smyth, Ian, Gillies, Susan, Negus, Kylie, Graham, Scott, Suthers, Graeme, Haites, Neva, Edwards, Matt, Wainwright, Brandon and Chenevix-Trench, Georgia (1997). Most germ-line mutations in the nevoid basal cell carcinoma syndrome lead to a premature termination of the PATCHED protein, and no genotype-phenotype correlations are evident. American Journal of Human Genetics, 60 (1), 21-26.

Wicking, C., Gillies, S., Smyth, I., Shanley, S., Fowles, L., Ratcliffe, J., Wainwright, B. and Chenevix-Trench, G. (1997). De novo mutations of the patched gene in nevoid basal cell carcinoma syndrome help to define the clinical phenotype. American Journal of Medical Genetics Part A, 73 (3), 304-307. doi: 10.1002/(SICI)1096-8628(19971219)73:3<304::AID-AJMG14>3.0.CO;2-N

Hahn, H, Wicking, C, Zaphiropoulos, PG, Gailani, MR, Shanley, S, Chidambaram, A, Vorechovsky, , Holmberg, E, Unden, AB, Gillies, S, Negus, K, Smyth, , Pressman, C, Leffell, DJ, Gerrard, B, Goldstein, AM, Dean, M, Toftgard, R, ChenevixTrench, G, Wainwright, B and Bale, AE (1996). Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome. Cell, 85 (6), 841-851. doi: 10.1016/S0092-8674(00)81268-4

Hahn, Heidi, Christiansen, Jeffrey, Wicking, Carol, Zaphiropoulos, Peter G., Chidambaram, Abirami, Gerrard, Bernard, Vorechovsky, Igor, Bale, Allen E., Toftgard, Rune, Dean, Michael and Wainwright, Brandon (1996). A mammalian patched homolog is expressed in target tissues of sonic hedgehog and maps to a region associated with developmental abnormalities. Journal of Biological Chemistry, 271 (21), 12125-12128. doi: 10.1074/jbc.271.21.12125

Negus, K, Holmes, GH, Wicking, C, Wainwright, BJ and Little, MH (1996). +P5(D1S3309E), a novel target binding site for the Wilms' tumour suppressor 1 (WT1) gene, maps to human chromosome 1q21->q22. Cytogenetics and Cell Genetics, 72 (4), 306-309. doi: 10.1159/000134210

Christiansen, Jeffrey H., Dennis, Carina L., Wicking, Carol A., Monkley, Susan J., Wilkinson, David G. and Wainwright, Brandon J. (1995). Murine Wnt-11 and Wnt-12 have temporally and spatially restricted expression patterns during embryonic development. Mechanisms of Development, 51 (2-3), 341-350. doi: 10.1016/0925-4773(95)00383-5

WICKING, C, BREEN, M, NEGUS, K, BERKMAN, J, EVDOKIOU, A, COWLED, P, CHENEVIXTRENCH, G and WAINWRIGHT, B (1995). THE HUMAN GROWTH-ARREST-SPECIFIC GENE GAS 1 MAPS OUTSIDE THE CANDIDATE REGION OF THE GENE FOR NEVOID BASAL-CELL CARCINOMA SYNDROME. Cytogenetics and Cell Genetics, 68 (1-2), 119-121. doi: 10.1159/000133904

SHANLEY, SM, DAWKINS, H, WAINWRIGHT, BJ, WICKING, C, HEENAN, P, ELDON, M, SEARLE, J and CHENEVIXTRENCH, G (1995). FINE DELETION MAPPING ON THE LONG ARM OF CHROMOSOME-9 IN SPORADIC AND FAMILIAL BASAL-CELL CARCINOMAS. Human Molecular Genetics, 4 (1), 129-133.

M.shanley, Susan, Dawkins, Hugh, J.wainwright, Brandon, Wicking, Carol, Heenan, Peter, Eldon, Michael, Searle, Jeffrey and Chenevlx-trench, Georgia (1995). Fine deletion mapping on the long arm of chromosome 9 in sporadic and familial basal cell carcinomas. Human Molecular Genetics, 4 (1), 129-133. doi: 10.1093/hmg/4.1.129

SHANLEY, S, RATCLIFFE, J, HOCKEY, A, HAAN, E, OLEY, C, RAVINE, D, MARTIN, N, WICKING, C and CHENEVIXTRENCH, G (1994). NEVOID BASAL-CELL CARCINOMA SYNDROME - REVIEW OF 118 AFFECTED INDIVIDUALS. American Journal of Medical Genetics, 50 (3), 282-290. doi: 10.1002/ajmg.1320500312

Wicking C., Berkman J., Wainwright B. and Chenevix-Trench G. (1994). Fine genetic mapping of the gene for nevoid basal cell carcinoma syndrome. Genomics, 22 (3), 505-511. doi: 10.1006/geno.1994.1423

Berkman, Jenny, Armour, John A.L., Chenevix-trench, Georgia, Wicking, Carol and Wainwright, Brandon (1994). Simple repeat polymorphism at the D9S151 locus. Human Molecular Genetics, 3 (1), 211-211. doi: 10.1093/hmg/3.1.211

CHENEVIXTRENCH, G, WICKING, C, BERKMAN, J, SHARPE, H, HOCKEY, A, HAAN, E, OLEY, C, RAVINE, D, TURNER, A, GOLDGAR, D, SEARLE, J and WAINWRIGHT, B (1993). FURTHER LOCALIZATION OF THE GENE FOR NEVOID BASAL-CELL CARCINOMA SYNDROME (NBCCS) IN 15 AUSTRALASIAN FAMILIES - LINKAGE AND LOSS OF HETEROZYGOSITY. American Journal of Human Genetics, 53 (3), 760-767.

WICKING, C and WILLIAMSON, B (1991). FROM LINKED MARKER TO GENE. Trends in Genetics, 7 (9), 288-293. doi: 10.1016/0168-9525(91)90177-R

TATA, F, STANIER, P, WICKING, C, HALFORD, S, KRUYER, H, LENCH, NJ, SCAMBLER, PJ, HANSEN, C, BRAMAN, JC, WILLIAMSON, R and WAINWRIGHT, BJ (1991). CLONING THE MOUSE HOMOLOG OF THE HUMAN CYSTIC-FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR GENE. Genomics, 10 (2), 301-307. doi: 10.1016/0888-7543(91)90312-3

RAMSAY, M, WAINWRIGHT, BJ, FARRALL, M, ESTIVILL, , SUTHERLAND, H, HO, MF, DAVIES, R, HALFORD, S, TATA, F, WICKING, C, LENCH, N, BAUER, , FEREC, C, FARNDON, P, KRUYER, H, STANIER, P, WILLIAMSON, R and SCAMBLER, PJ (1990). A NEW POLYMORPHIC LOCUS, D7S411, ISOLATED BY CLONING FROM PREPARATIVE PULSE-FIELD GELS IS CLOSE TO THE MUTATION CAUSING CYSTIC-FIBROSIS. Genomics, 6 (1), 39-47. doi: 10.1016/0888-7543(90)90446-2

WAINWRIGHT, BJ, SCAMBLER, PJ, STANIER, P, WATSON, EK, BELL, G, WICKING, C, ESTIVILL, , COURTNEY, M, BOUE, A, PEDERSEN, PS, WILLIAMSON, R and FARRALL, M (1988). ISOLATION OF A HUMAN-GENE WITH PROTEIN-SEQUENCE SIMILARITY TO HUMAN AND MURINE INT-1 AND THE DROSOPHILA SEGMENT POLARITY MUTANT WINGLESS. Embo Journal, 7 (6), 1743-1748. doi: 10.1002/j.1460-2075.1988.tb03003.x

Wainwright, B. J., Scambler, P. J., Stanier, P., Watson, E. K., Bell, G., Wicking, C., Estivill, X., Courtney, M., Boue, A. and Pedersen, P. S. (1988). Isolation of a human gene with protein sequence similarity to human and murine int-1 and the Drosophila segment polarity mutant wingless. EMBO Journal, 7 (6), 1743-1748.

Metzis, Vicki, Courtney, Andrew, Ferguson, Charles, Cooper, Ashley, Wainwright, Brandon and Wicking, Carol (2011). Patched1 is essential for nasal pit invagination in mouse. Society for Developmental Biology 70th Annual Meeting, Chicago IL, United States, 21-25 July 2011. Maryland Heights MO, United States: Academic Press. doi: 10.1016/j.ydbio.2011.05.164

Turchi, L., Fareh, M., Aberdam, E., Kitajima, S., Simpson, F., Wicking, C., Aberdam, D. and Virolle, T. (2008). ATF3 and p15PAF are novel gatekeepers of genomic integrity upon UV stress. 20th Meeting of the European Association for Cancer Research, Lyon, France, 5-8 July 2008. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD. doi: 10.1016/S1359-6349(08)71531-3

Town, L. J., Simpson, F., McGlinn, E. C., Butterfield, N., Richman, J. M. and Wicking, C. (2007). A novel RhoA inhibitor implicated in lip and palate formation. Society for Developmental Biology 66th Annual Meeting, Gran Meliá Hotel, Cancún, México, 16th – 20th June, 2007. Oxford: Elsevier Inc.. doi: 10.1016/j.ydbio.2007.03.512

Town, L., McGlinn, E., Simpson, F., Richman, J. and Wicking, C. (2005). A novel Gli3-regulated gene implicated in lip and palate formation. AMSTERDAM: ELSEVIER SCIENCE BV.

Butterfield, N. C., Simpson, F., Bennetts, J. S., Fowles, L. F. and Wicking, C. A. (2005). Analysis of the subcellular role of a gene isolated from the craniofacial region of the mouse. Unknown, Unknown, Unknown. Amsterdam, Netherlands: Elsevier Science.

Simpson, F., van Bueren, Lammerts K., Fowles, L., Berkman, J., Butterfield, N., Bowles, J., Adolphe, C., Simms, L., Young, J., Walsh, M. and Wicking, C. (2005). The PCNA-associated factor KIAA0101/p15(PAF) binds the potential tumour suppressor product p33ING1. Unknown, Unknown, Unknown. Amsterdam, Netherlands: Elsevier Science.

Bennetts, J., Fowles, L., Butterfield, N., van Bueren, Lammerts K., Berkman, J., Simpson, F. and Wicking, C. (2005). Identification and characterisation of novel genes with developmental significance. Unknown, Unknown, Unknown. Shannon, Co. Clare, Ireland: Elsevier Ireland.

Nawshad, A., Joseph, B. K., Savage, N. W., Young, W., Wicking, C. A., Smyth, I. M. and Rothnagel, J. A. (1999). Patched and cytokeratin localization in odontogenic keratocysts. Australian & New Zealand Division 38th Annual Scientific Meeting, Brisbane, Australia, 27-29 September, 1998. Chicago, Ill.: American Association for Dental Res.. doi: 10.1177/00220345990780051301

Evans, T. M. and Wicking, C. (2006). Rab23.

Dr Carol Wicking

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