Book Chapters
Butler, Mark S. (2010). A snapshot of natural product-derived compounds in late stage clinical development at the end of 2008. Natural product chemistry for drug discovery. (pp. 321-354) edited by Antony D. Buss and Mark S. Butler. Cambridge, United Kingdom: Royal Society of Chemistry. doi: 10.1039/9781847559890-00321
Butler, Mark S. and Newman, David J. (2008). Mother Nature's gifts to diseases of man: The impact of natural products on anti-infective, anticholestemics and anticancer drug discovery. Natural compounds as drugs, volume I. (pp. 1-44) edited by Frank Petersen and René Amstutz. Basel, Switzerland: Birkauser Verlag.
Journal Articles
Butler, Mark S., Vollmer, Waldemar, Goodall, Emily C. A., Capon, Robert J., Henderson, Ian R. and Blaskovich, Mark A. T. (2024). A Review of Antibacterial Candidates with New Modes of Action. ACS Infectious Diseases, 10 (10), 3440-3474. doi: 10.1021/acsinfecdis.4c00218
Lacey, Alastair E., Minns, Scott A., Chen, Rachel, Vuong, Daniel, Lacey, Ernest, Kalaitzis, John A., Tan, Yu Pei, Shivas, Roger G., Butler, Mark S. and Piggott, Andrew M. (2023). Talcarpones A and B: bisnaphthazarin-derived metabolites from the Australian fungus Talaromyces johnpittii sp. nov. MST-FP2594. Journal of Antibiotics, 77 (3), 147-155. doi: 10.1038/s41429-023-00688-x
Salim, Angela A., Butler, Mark S., Blaskovich, Mark A. T., Henderson, Ian R. and Capon, Robert J. (2023). Natural products as anthelmintics: safeguarding animal health. Natural Product Reports, 40 (11), 1754-1808. doi: 10.1039/d3np00019b
Overman, Jeroen, Fontaine, Frank, Moustaqil, Mehdi, Mittal, Deepak, Sierecki, Emma, Sacilotto, Natalia, Zuegg, Johannes, Robertson, Avril AB, Holmes, Kelly, Salim, Angela A, Mamidyala, Sreeman, Butler, Mark S, Robinson, Ashley S, Lesieur, Emmanuelle, Johnston, Wayne, Alexandrov, Kirill, Black, Brian L, Hogan, Benjamin M, De Val, Sarah, Capon, Robert J, Carroll, Jason S, Bailey, Timothy L, Koopman, Peter, Jauch, Ralf, Cooper, Matthew A, Gambin, Yann and Francois, Mathias (2023). Correction: Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice. eLife, 12 ARTN e90408. doi: 10.7554/elife.90408
Chen, Rachel, Minns, Scott A., Kalaitzis, John A., Butler, Mark S., Rosin, Maira, Vuong, Daniel, Lean, Soo Sum, Chooi, Yit-Heng, Lacey, Ernest and Piggott, Andrew M. (2023). Turonicin A, an antifungal linear polyene polyketide from an Australian Streptomyces sp. Journal of Natural Products, 86 (8), 2054-2058. doi: 10.1021/acs.jnatprod.3c00144
Pham, Nhan T., Alves, Joana, Sargison, Fiona A., Cullum, Reiko, Wildenhain, Jan, Fenical, William, Butler, Mark S., Mead, David A., Duggan, Brendan M., Fitzgerald, J. Ross, La Clair, James J. and Auer, Manfred (2023). Nanoscaled discovery of a shunt rifamycin from Salinispora arenicola using a three-color GFP-tagged Staphylococcus aureus macrophage infection assay. ACS Infectious Diseases, 9 (8), 1499-1507. doi: 10.1021/acsinfecdis.3c00049
Butler, Mark S., Henderson, Ian R., Capon, Robert J. and Blaskovich, Mark A. T. (2023). Antibiotics in the clinical pipeline as of December 2022. The Journal of Antibiotics, 76 (8), 431-473. doi: 10.1038/s41429-023-00629-8
Zhang, Bing, Phetsang, Wanida, Stone, M. Rhia L., Kc, Sanjaya, Butler, Mark S., Cooper, Matthew A., Elliott, Alysha G., Łapińska, Urszula, Voliotis, Margaritis, Tsaneva-Atanasova, Krasimira, Pagliara, Stefano and Blaskovich, Mark A. T. (2023). Synthesis of vancomycin fluorescent probes that retain antimicrobial activity, identify Gram-positive bacteria, and detect Gram-negative outer membrane damage. Communications Biology, 6 (1) 409, 1-16. doi: 10.1038/s42003-023-04745-x
Minns, Scott A., Bowles, Simon, Lacey, Ernest, Kalaitzis, John A., Vuong, Daniel, Butler, Mark S. and Piggott, Andrew M. (2023). Fuligopyrones from the fruiting bodies of myxomycete Fuligo septica offer short-term protection from abiotic stress induced by UV radiation. Journal of Natural Products, 86 (3), 633-637. doi: 10.1021/acs.jnatprod.2c00989
Butler, Mark S., Henderson, Ian R., Capon, Robert J. and Blaskovich, Mark A. T. (2023). Correction: Antibiotics in the clinical pipeline as of December 2022 (The Journal of Antibiotics, (2023), 76, 8, (431-473), 10.1038/s41429-023-00629-8). Journal of Antibiotics, 77 (1), 71-71. doi: 10.1038/s41429-023-00671-6
Sulaiman, Mazdida, Zarubaev, Vladimir, Samudi, Chandramathi, Rahmatullah, Mohammed, Jannat, Khoshnur, Paul, Alok, Rajagopal, Mogana, Salvaraj, Malarvili, Nissapatorn, Veeranoot, Suleiman, Monica, Butler, Mark and Wiart, Christophe (2022). Natural products from medicinal plants in Asia and the Pacific for RNA viruses: Hercules’ fifth labour. Pharmaceutical Biology, 60 (1), 2049-2087. doi: 10.1080/13880209.2022.2130944
Blaskovich, Mark A.T., Hansford, Karl A., Butler, Mark S., Ramu, Soumya, Kavanagh, Angela M., Jarrad, Angie M., Prasetyoputri, Anggia, Pitt, Miranda E., Huang, Johnny X., Lindahl, Fredrik, Ziora, Zyta M., Bradford, Tanya, Muldoon, Craig, Rajaratnam, Premraj, Pelingon, Ruby, Edwards, David J., Zhang, Bing, Amado, Maite, Elliott, Alysha G., Zuegg, Johannes, Coin, Lachlan, Woischnig, Anne-Kathrin, Khanna, Nina, Breidenstein, Elena, Stincone, Anna, Mason, Clive, Khan, Nawaz, Cho, Hye-Kyung, Karau, Melissa J. ... Cooper, Matthew A. (2022). A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections. Science Translational Medicine, 14 (662) abj2381, 1-16. doi: 10.1126/scitranslmed.abj2381
Blaskovich, Mark A.T., Hansford, Karl A., Butler, Mark S., Ramu, Soumya, Kavanagh, Angela M., Jarrad, Angie M., Prasetyoputri, Anggia, Pitt, Miranda E., Huang, Johnny X., Lindahl, Fredrik, Ziora, Zyta M., Bradford, Tanya, Muldoon, Craig, Rajaratnam, Premraj, Pelingon, Ruby, Edwards, David J., Zhang, Bing, Amado, Maite, Elliott, Alysha G., Zuegg, Johannes, Coin, Lachlan, Woischnig, Anne-Kathrin, Khanna, Nina, Breidenstein, Elena, Stincone, Anna, Mason, Clive, Khan, Nawaz, Cho, Hye-Kyung, Karau, Melissa J. ... Cooper, Matthew A. (2022). A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections. Science Translational Medicine, 14 (662) abj2381. doi: 10.1126/scitranslmed.abj238
Sulaiman, Mazdida, Jannat, Khoshnur, Nissapatorn, Veeranoot, Rahmatullah, Mohammed, Paul, Alok K., de Lourdes Pereira, Maria, Rajagopal, Mogana, Suleiman, Monica, Butler, Mark S., Break, Mohammed Khaled Bin, Weber, Jean-Frédéric, Wilairatana, Polrat and Wiart, Christophe (2022). Antibacterial and antifungal alkaloids from Asian angiosperms: distribution, mechanisms of action, structure-activity, and clinical potentials. Antibiotics, 11 (9) 1146, 1-38. doi: 10.3390/antibiotics11091146
Zulkipli, Masyitah, Mahbub, Nuzum, Fatima, Ayesha, Wan-Lin, Stefanie Lim, Khoo, Teng-Jin, Mahboob, Tooba, Rajagopal, Mogana, Samudi, Chandramathi, Kathirvalu, Gheetanjali, Abdullah, Nor Hayati, Pinho, Ana Rita, Oliveira, Sonia M. R., Pereira, Maria de Lourdes, Rahmatullah, Mohammed, Hasan, Anamul, Paul, Alok K., Butler, Mark S., Nawaz, Muhammad, Wilairatana, Polrat, Nissapatorn, Veeranoot and Wiart, Christophe (2022). Isolation and characterization of Werneria Chromene and Dihydroxyacidissimol from Burkillanthus malaccensis (Ridl.) Swingle. Plants, 11 (11) 1388, 1388. doi: 10.3390/plants11111388
Li, Hang, Mirzayans, Paul M., Butler, Mark S., Lacey, Alastair E., Vuong, Daniel, Chen, Rachel, Kalaitzis, John A., Moggach, Stephen A., Lacey, Ernest, Piggott, Andrew M. and Chooi, Yit-Heng (2022). Discovery of brevijanazines from Aspergillus brevijanus reveals the molecular basis for p-nitrobenzoic acid in fungi. Chemical Communications, 58 (43), 6296-6299. doi: 10.1039/d2cc01679f
Butler, Mark S., Gigante, Valeria, Sati, Hatim, Paulin, Sarah, Al-Sulaiman, Laila, Rex, John H., Fernandes, Prabhavathi, Arias, Cesar A., Paul, Mical, Thwaites, Guy E., Czaplewski, Lloyd, Alm, Richard A., Lienhardt, Christian, Spigelman, Melvin, Silver, Lynn L., Ohmagari, Norio, Kozlov, Roman, Harbarth, Stephan and Beyer, Peter (2022). Reply to Kaye and Belley, “Third-Generation Cephalosporin-Resistant Enterobacterales Are Critical Priority Pathogens, Too!”. Antimicrobial Agents and Chemotherapy, 66 (4) e0022322, e0022322. doi: 10.1128/aac.00223-22
Butler, Mark S., Gigante, Valeria, Sati, Hatim, Paulin, Sarah, Al-Sulaiman, Laila, Rex, John H., Fernandes, Prabhavathi, Arias, Cesar A., Paul, Mical, Thwaites, Guy E., Czaplewski, Lloyd, Alm, Richard A., Lienhardt, Christian, Spigelman, Melvin, Silver, Lynn L., Ohmagari, Norio, Kozlov, Roman, Harbarth, Stephan and Beyer, Peter (2022). Analysis of the clinical pipeline of treatments for drug resistant bacterial infections: despite progress, more action is needed. Antimicrobial Agents and Chemotherapy, 66 (3) e01991-21, e0199121. doi: 10.1128/aac.01991-21
Abdul Rahim, Nusaibah, Zhu, Yan, Cheah, Soon-Ee, Johnson, Matthew D., Yu, Heidi H., Sidjabat, Hanna E., Butler, Mark S., Cooper, Matthew A., Fu, Jing, Paterson, David L., Nation, Roger L., Boyce, John D., Creek, Darren J., Bergen, Phillip J., Velkov, Tony and Li, Jian (2021). Synergy of the polymyxin-chloramphenicol combination against New Delhi metallo-β-lactamase-producing Klebsiella pneumoniae is predominately driven by chloramphenicol. ACS Infectious Diseases, 7 (6), 1584-1595. doi: 10.1021/acsinfecdis.0c00661
Mitsuwan, Watcharapong, Sangkanu, Suthinee, Romyasamit, Chonticha, Kaewjai, Chalermpon, Jimoh, Tajudeen O., de Lourdes Pereira, Maria, Siyadatpanah, Abolghasem, Kayesth, Sunil, Nawaz, Muhammad, Rahmatullah, Mohammed, Butler, Mark S., Wilairatana, Polrat, Wiart, Christophe and Nissapatorn, Veeranoot (2020). Curcuma longa rhizome extract and Curcumin reduce the adhesion of Acanthamoeba triangularis trophozoites and cysts in polystyrene plastic surface and contact lens. International Journal for Parasitology: Drugs and Drug Resistance, 14, 218-229. doi: 10.1016/j.ijpddr.2020.11.001
Abdul Rahim, Nusaibah, Cheah, Soon-Ee, Johnson, Matthew D., Zhu, Yan, Yu, Heidi H., Sidjabat, Hanna E., Butler, Mark S., Cooper, Matthew A., Fu, Jing, Paterson, David L., Nation, Roger L., Boyce, John D., Bergen, Phillip J., Velkov, Tony and Li, Jian (2020). Transcriptomic responses of a New Delhi metallo-β-lactamase-producing Klebsiella pneumoniae isolate to the combination of polymyxin B and chloramphenicol. International Journal of Antimicrobial Agents, 56 (2) 106061, 106061. doi: 10.1016/j.ijantimicag.2020.106061
Elliott, Alysha G., Huang, Johnny X., Neve, Søren, Zuegg, Johannes, Edwards, Ingrid A., Cain, Amy K., Boinett, Christine J., Barquist, Lars, Lundberg, Carina Vingsbo, Steen, Jason, Butler, Mark S., Mobli, Mehdi, Porter, Kaela M., Blaskovich, Mark A. T., Lociuro, Sergio, Strandh, Magnus and Cooper, Matthew A. (2020). An amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteria. Nature Communications, 11 (1) 3184, 3184. doi: 10.1038/s41467-020-16950-x
Butler, Mark S. and Paterson, David L. (2020). Antibiotics in the clinical pipeline in October 2019. The Journal of Antibiotics, 73 (6), 329-364. doi: 10.1038/s41429-020-0291-8
Jiao, Wei-Hua, Salim, Angela A., Khalil, Zeinab G., Dewapriya, Pradeep, Lin, Hou-Wen, Butler, Mark S. and Capon, Robert J. (2019). Trivirensols: selectively bacteriostatic sesquiterpene trimers from the Australian termite nest-derived fungus Trichoderma virens CMB-TN16. Journal of Natural Products, 82 (11), 3165-3175. doi: 10.1021/acs.jnatprod.9b00760
Hossan, Md Shahadat, Chan, Zi-Yang, Collins, Hilary M., Shipton, Fiona N., Butler, Mark S., Rahmatullah, Mohammed, Lee, Jong Bong, Gershkovich, Pavel, Kagan, Leonid, Khoo, Teng-Jin, Wiart, Christophe and Bradshaw, Tracey D. (2019). Cardiac glycoside cerberin exerts anticancer activity through PI3K/AKT/mTOR signal transduction inhibition. Cancer Letters, 453, 57-73. doi: 10.1016/j.canlet.2019.03.034
Gallardo-Godoy, Alejandra, Hansford, Karl, Muldoon, Craig, Becker, Bernd, Elliott, Alysha, Huang, Johnny, Pelingon, Ruby, Butler, Mark, Blaskovich, Mark and Cooper, Matthew (2019). Structure-function studies of polymyxin B lipononapeptides. Molecules, 24 (3) 553, 553. doi: 10.3390/molecules24030553
Theuretzbacher, Ursula, Gottwalt, Simon, Beyer, Peter, Butler, Mark, Czaplewski, Lloyd, Lienhardt, Christian, Moja, Lorenzo, Paul, Mical, Paulin, Sarah, Rex, John H., Silver, Lynn L., Spigelman, Melvin, Thwaites, Guy E., Paccaud, Jean-Pierre and Harbarth, Stephan (2019). Analysis of the clinical antibacterial and antituberculosis pipeline. Lancet Infectious Diseases, 19 (2), E40-E50. doi: 10.1016/S1473-3099(18)30513-9
McAlpine, James B., Chen, Shao-Nong, Kutateladze, Andrei, MacMillan, John B., Appendino, Giovanni, Barison, Andersson, Beniddir, Mehdi A., Biavatti, Maique W., Bluml, Stefan, Boufridi, Asmaa, Butler, Mark S., Capon, Robert J., Choi, Young H., Coppage, David, Crews, Phillip, Crimmins, Michael T., Csete, Marie, Dewapriya, Pradeep, Egan, Joseph M., Garson, Mary J., Genta-Jouve, Grégory, Gerwick, William H., Gross, Harald, Harper, Mary Kay, Hermanto, Precilia, Hook, James M., Hunter, Luke, Jeannerat, Damien, Ji, Nai-Yun ... Pauli, Guido F. (2019). Correction: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research. Natural Product Reports, 36 (1), 248-249. doi: 10.1039/c8np90041h
Chitty, Jessica L., Edwards, David J., Robertson, Avril A. B., Butler, Mark S., Duley, John A., Cooper, Matthew A. and Fraser, James A. (2019). Quantitation of Purines from Pigeon Guano and Implications for Cryptococcus neoformans Survival During Infection. Mycopathologia, 184 (2), 273-281. doi: 10.1007/s11046-018-0315-0
Jarrad, Angie M., Ang, Chee Wei, Debnath, Anjan, Hahn, Hye Jee, Woods, Kyra, Tan, Lendl, Sykes, Melissa L., Jones, Amy J., Pelingon, Ruby, Butler, Mark S., Avery, Vicky M., West, Nicholas P., Karoli, Tomislav, Blaskovich, Mark A. T. and Cooper, Matthew A. (2018). Design, synthesis and biological evaluation of 2-nitroimidazopyrazin-one/-es with antitubercular and antiparasitic activity. Journal of Medicinal Chemistry, 61 (24) acs.jmedchem.8b01578, 11349-11371. doi: 10.1021/acs.jmedchem.8b01578
Pitt, Miranda E., Cao, Minh Duc, Butler, Mark S., Ramu, Soumya, Ganesamoorthy, Devika, Blaskovich, Mark A. T., Coin, Lachlan J. M. and Cooper, Matthew A. (2018). Octapeptin C4 and polymyxin resistance occur via distinct pathways in an epidemic XDR Klebsiella pneumoniae ST258 isolate. The Journal of Antimicrobial Chemotherapy, 74 (3), 582-593. doi: 10.1093/jac/dky458
Nor Azman, Nadiah Syafiqah, Hossan, Md Shahadat, Nissapatorn, Veeranoot, Uthaipibull, Chairat, Prommana, Parichat, Jin, Khoo Teng, Rahmatullah, Mohammed, Mahboob, Tooba, Raju, Chandramathi Samudi, Jindal, Hassan Mahmood, Hazra, Banasri, Mohd Abd Razak, Mohd Ridzuan, Prajapati, Vijay Kumar, Pandey, Rajan Kumar, Aminudin, Norhaniza, Shaari, Khozirah, Ismail, Nor Hadiani, Butler, Mark S., Zarubaev, Vladimir V. and Wiart, Christophe (2018). Anti-infective activities of 11 plants species used in traditional medicine in Malaysia. Experimental Parasitology, 194, 67-78. doi: 10.1016/j.exppara.2018.09.020
Gordon, Richard, Albornoz, Eduardo A., Christie, Daniel C., Langley, Monica R., Kumar, Vinod, Mantovani, Susanna, Robertson, Avril A. B., Butler, Mark S., Rowe, Dominic B., O'Neill, Luke A., Kanthasamy, Anumantha G., Schroder, Kate, Cooper, Matthew A. and Woodruff, Trent M. (2018). Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice. Science Translational Medicine, 10 (465) aah4066, eaah4066. doi: 10.1126/scitranslmed.aah4066
Kummari, Lalith K., Butler, Mark S., Furlong, Emily, Blundell, Ross, Nouwens, Amanda, Silva, Alberto B., Kappler, Ulrike, Fraser, James A., Kobe, Bostjan, Cooper, Matthew A. and Robertson, Avril A.B. (2018). Antifungal benzo[b]thiophene 1,1-dioxide IMPDH inhibitors exhibit pan-assay interference (PAINS) profiles. Bioorganic and Medicinal Chemistry, 26 (20), 5408-5419. doi: 10.1016/j.bmc.2018.09.004
McAlpine, James B., Chen, Shao-Nong, Kutateladze, Andrei, MacMillan, John B., Appendino, Giovanni, Barison, Andersson, Beniddir, Mehdi A., Biavatti, Maique W., Bluml, Stefan, Boufridi, Asmaa, Butler, Mark S., Capon, Robert J., Choi, Young H., Coppage, David, Crews, Phillip, Crimmins, Michael T., Csete, Marie, Dewapriya, Pradeep, Egan, Joseph M., Garson, Mary J., Genta-Jouve, Grégory, Gerwick, William H., Gross, Harald, Harper, Mary Kay, Hermanto, Precilia, Hook, James M., Hunter, Luke, Jeannerat, Damien, Ji, Nai-Yun ... Pauli, Guido F. (2018). The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research. Natural Product Reports, 36 (1), 35-107. doi: 10.1039/c7np00064b
Butler, Mark S., Healy, Peter C., Forster, Paul I., Guymer, Gordon P. and Quinn, Ronald J. (2018). 5,6,7,3',4',5'-Hexamethoxyflavone from the Australian plant Eremophila debilis (Myoporaceae). Fitoterapia, 126, 90-92. doi: 10.1016/j.fitote.2017.07.014
Stone, M Rhia L., Butler, Mark S., Phetsang, Wanida, Cooper, Matthew A. and Blaskovich, Mark A. T. (2018). Fluorescent Antibiotics: New Research Tools to Fight Antibiotic Resistance. Trends in Biotechnology, 36 (5), 523-536. doi: 10.1016/j.tibtech.2018.01.004
Salla, Manohar, Butler, Mark S., Massey, Nicholas L., Reid, Janet C., Cooper, Matthew A. and Robertson, Avril A. B. (2018). Synthesis of deuterium-labelled analogues of NLRP3 inflammasome inhibitor MCC950. Bioorganic and Medicinal Chemistry Letters, 28 (4), 793-795. doi: 10.1016/j.bmcl.2017.12.054
Kammoun, H. L., Allen, T. L., Henstridge, D. C., Barre, S., Coll, R. C., Lancaster, G. I., Cron, L., Reibe, S., Chan, J. Y., Bensellam, M., Laybutt, D. R., Butler, M. S., Robertson, A. A. B., O'Neill, L. A., Cooper, M. A. and Febbraio, M. A. (2018). Evidence against a role for NLRP3-driven islet inflammation in db/db mice. Molecular Metabolism, 10, 66-73. doi: 10.1016/j.molmet.2018.02.001
Velkov, Tony, Gallardo-Godoy, Alejandra, Swarbrick, James D., Blaskovich, Mark A. T., Elliott, Alysha G., Han, Meiling, Thompson, Philip E., Roberts, Kade D., Huang, Johnny X., Becker, Bernd, Butler, Mark S., Lash, Lawrence H., Henriques, Sónia Troeira, Nation, Roger L., Sivanesan, Sivashangarie, Sani, Marc-Antoine, Separovic, Frances, Mertens, Haydyn, Bulach, Dieter, Seemann, Torsten, Owen, Jeremy, Li, Jian and Cooper, Matthew A. (2018). Structure, Function, and Biosynthetic Origin of Octapeptin Antibiotics Active against Extensively Drug-Resistant Gram-Negative Bacteria. Cell Chemical Biology, 25 (4), 380-391.e5. doi: 10.1016/j.chembiol.2018.01.005
Blaskovich, Mark A. T., Hansford, Karl A., Butler, Mark S., Jia, ZhiGuang, Mark, Alan E. and Cooper, Matthew A. (2018). Developments in Glycopeptide Antibiotics. ACS Infectious Diseases, 4 (5), 715-735. doi: 10.1021/acsinfecdis.7b00258
Blaskovich, Mark A T, Hansford, Karl A., Gong, Yujing, Butler, Mark S., Muldoon, Craig, Huang, Johnny X., Ramu, Soumya, Silva, Alberto B., Cheng, Mu, Kavanagh, Angela M., Ziora, Zyta, Premraj, Rajaratnam, Lindahl, Fredrik, Bradford, Tanya A., Lee, June C., Karoli, Tomislav, Pelingon, Ruby, Edwards, David J., Amado, Maite, Elliott, Alysha G, Phetsang, Wanida, Daud, Noor Huda, Deecke, Johan E, Sidjabat, Hanna E, Ramaologa, Sefetogi, Zuegg, Johannes, Betley, Jason R, Beevers, Andrew P G, Smith, Richard A G ... Cooper, Matthew A. (2018). Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria. Nature Communications, 9 (1) 02123, 22. doi: 10.1038/s41467-017-02123-w
Chitty, Jessica L., Butler, Mark S., Suboh, Azzah, Edwards, David J., Cooper, Matthew A., Fraser, James A. and Robertson, Avril A. B. (2017). Antimicrobial octapeptin C4 analogues active against Cryptococcus species. Antimicrobial agents and chemotherapy, 62 (2) e00986-17, 1-10. doi: 10.1128/AAC.00986-17
Chitty, Jessica L., Blake, Kirsten L., Blundell, Ross D., Koh, Y. Q. Andre E., Thompson, Merinda, Robertson, Avril A. B., Butler, Mark S., Cooper, Matthew A., Kappler, Ulrike, Williams, Simon J., Kobe, Bostjan and Fraser, James A. (2017). Cryptococcus neoformans ADS lyase is an enzyme essential for virulence whose crystal structure reveals features exploitable in antifungal drug design. Journal of Biological Chemistry, 292 (28), 11829-11839. doi: 10.1074/jbc.M117.787994
Becker, Bernd, Butler, Mark S., Hansford, Karl A., Gallardo-Godoy, Alejandra, Elliott, Alysha G., Huang, Johnny X., Edwards, David J., Blaskovich, Mark A. T. and Cooper, Matthew A. (2017). Synthesis of octapeptin C4 and biological profiling against NDM-1 and polymyxin-resistant bacteria. Bioorganic and Medicinal Chemistry Letters, 27 (11), 2407-2409. doi: 10.1016/j.bmcl.2017.04.027
Galappathie, Savithri, Edwards, David J., Elliott, Alysha G., Cooper, Matthew A., Palombo, Enzo A., Butler, Mark S. and Mahon, Peter J. (2017). Antibacterial nerol cinnamates from the Australian plant Eremophila longifolia. Journal of Natural Products, 80 (4), 1178-1181. doi: 10.1021/acs.jnatprod.6b00888
Blaskovich, Mark A. T., Butler, Mark S. and Cooper, Matthew A. (2017). Polishing the tarnished silver bullet: the quest for new antibiotics. Antimicrobial Resistance, 61 (1), 103-114. doi: 10.1042/EBC20160077
Chitty, Jessica L., Tatzenko, Tayla L. , Williams, Simon J., Koh, Y. Q. Andre E., Corfield, Elizabeth C., Butler, Mark S., Robertson, Avril A. B., Cooper, Matthew A., Kappler, Ulrike, Kobe, Bostjan and Fraser, James A. (2017). GMP synthase is required for virulence factor production and infection by cryptococcus neoformans. Journal of Biological Chemistry, 292 (7), 3049-3059. doi: 10.1074/jbc.M116.767533
Overman, Jeroen, Fontaine, Frank, Moustaqil, Mehdi, Mittal, Deepak, Sierecki, Emma, Sacilotto, Natalia, Zuegg, Johannes, Robertson, Avril A. B., Holmes, Kelly, Salim, Angela A., Mamidyala, Sreeman, Butler, Mark S., Robinson, Ashley S., Lesieur, Emmanuelle, Johnston, Wayne, Alexandrov, Kirill, Black, Brian L., Hogan, Benjamin M., De Val, Sarah, Capon, Robert J., Carroll, Jason S., Bailey, Timothy L., Koopman, Peter, Jauch, Ralf, Smyth, Mark J., Cooper, Matthew A., Gambin, Yann and Francois, Mathias (2017). Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice. eLife, 6 e21221. doi: 10.7554/eLife.21221
Butler, Mark, Blaskovich, Mark, Owen, Jeremy G. and Cooper, Matthew (2016). Old dogs and new tricks in antimicrobial discovery. Current Opinion in Microbiology, 33, 25-34. doi: 10.1016/j.mib.2016.05.011
Salla, Manohar, Butler, Mark S., Pelingon, Ruby, Kaeslin, Geraldine, Croker, Daniel E., Reid, Janet C., Baek, Jong-Min, Bernhardt, Paul V., Gillam, Elizabeth M. J., Cooper, Matthew A. and Robertson, Avril A. B. (2016). Identification, synthesis, and biological evaluation of the major human metabolite of NLRP3 inflammasome inhibitor MCC950. ACS Medicinal Chemistry Letters, 7 (12), 1034-1038. doi: 10.1021/acsmedchemlett.6b00198
Jarrad, A. M., Debnath, A., Miyamoto, Y., Hansford, K. A., Pelingon, R., Butler, M. S., Bains, T., Karoli, T., Blaskovich, M. A. T., Eckmann, L. and Cooper, M. A. (2016). Nitroimidazole carboxamides as antiparasitic agents targeting Giardia lamblia, Entamoeba histolytica and Trichomonas vaginalis. European Journal of Medicinal Chemistry, 120, 353-362. doi: 10.1016/j.ejmech.2016.04.064
Blundell, Ross D., Williams, Simon J., Arras, Samantha D. M., Chitty, Jessica L., Blake, Kirsten L., Ericsson, Daniel J., Tibrewal, Nidhi, Rohr, Jurgen, Koh, Y. Q. Andre, Kappler, Ulrike, Robertson, Avril A. B., Butler, Mark S., Cooper, Matthew A., Kobe, Bostjan and Fraser, James A. (2016). Disruption of de novo adenosine triphosphate (ATP) biosynthesis abolishes virulence in Cryptococcus neoformans. ACS Infectious Diseases, 2 (9), 651-663. doi: 10.1021/acsinfecdis.6b00121
Butler, Mark S., Blaskovich, Mark A. T. and Cooper, Matthew A. (2016). Antibiotics in the clinical pipeline at the end of 2015. The Journal of Antibiotics, 70 (1), 1-22. doi: 10.1038/ja.2016.72
Watterson, Daniel, Robinson, Jodie, Chappell, Keith J., Butler, Mark S., Edwards, David J., Fry, Scott R., Bermingham, Imogen M., Cooper, Matthew A. and Young, Paul R. (2016). A generic screening platform for inhibitors of virus induced cell fusion using cellular electrical impedance. Scientific Reports, 6 (22791) 22791, 1-9. doi: 10.1038/srep22791
Gallardo-Godoy, Alejandra, Muldoon, Craig, Becker, Bernd, Elliott, Alysha G., Lash, Lawrence H, Huang, Johnny X., Butler, Mark S., Pelingon, Ruby, Kavanagh, Angela M., Ramu, Soumya, Phetsang, Wanida, Blaskovich, Mark A. T. and Cooper, Matthew A (2016). Activity and predicted nephrotoxicity of synthetic antibiotics based on polymyxin B. Journal of Medicinal Chemistry, 59 (3), 1068-1077. doi: 10.1021/acs.jmedchem.5b01593
Phetsang, Wanida, Pelingon, Ruby, Butler, Mark S., KC, Sanjaya, Pitt, Miranda, Kaeslin, Geraldine, Cooper, Matthew A. and Blaskovich, Mark A. T. (2016). Fluorescent trimethoprim conjugate probes to assess drug accumulation in wild type and mutant Escherichia coli. ACS Infectious Diseases, 2 (10), 688-701. doi: 10.1021/acsinfecdis.6b00080
Huang, Johnny X., Blaskovich, Mark A.T., Pelingon, Ruby, Ramu, Soumya, Kavanagh, Angela, Elliott, Alysha G., Butler, Mark S., Montgomery, A. Bruce and Cooper, Matthew A. (2015). Mucin binding reduces colistin antimicrobial activity. Antimicrobial Agents and Chemotherapy, 59 (10), 5925-5931. doi: 10.1128/AAC.00808-15
Rees, Karlee A., Bermudez, Cindy, Edwards, David J., Elliott, Alysha G., Ripen, Jovita E., Seta, Cynthia, Huang, Johnny X., Cooper, Matthew A., Fraser, James A., Yeo, Tiong C. and Butler, Mark S. (2015). Flemingin-type prenylated chalcones from the sarawak rainforest plant desmodium congestum. Journal of Natural Products, 78 (8), 2141-2144. doi: 10.1021/acs.jnatprod.5b00410
Zuegg, Johannes, Muldoon, Craig, Adamson, George, McKeveney, Declan, Le Thanh, Giang, Premraj, Rajaratnam, Becker, Bernd, Cheng, Mu, Elliott, Alysha G., Huang, Johnny X., Butler, Mark S., Bajaj, Megha, Seifert, Joachim, Singh, Latika, Galley, Nicola F., Roper, David I., Lloyd, Adrian J., Dowson, Christopher G., Cheng, Ting-Jen, Cheng, Wei-Chieh, Demon, Dieter, Meyer, Evelyne, Meutermans, Wim and Cooper, Matthew A. (2015). Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity. Nature Communications, 6 (1) 7719, 1-11. doi: 10.1038/ncomms8719
Hickey, Shane M., Ashton, Trent D., Khosa, Simren K., Robson, Ryan N., White, Jonathan M., Li, Jian, Nation, Roger L., Yu, Heidi Y., Elliott, Alysha G., Butler, Mark S., Huang, Johnny X., Cooper, Matthew A. and Pfeffer, Frederick M. (2015). Synthesis and evaluation of cationic norbornanes as peptidomimetic antibacterial agents. Organic and Biomolecular Chemistry, 13 (22), 6225-6241. doi: 10.1039/c5ob00621j
Huang, Johnny Xiao, Geraldine Kaeslin, Max Ranall, Blaskovich, Mark, Bernd Becker, Butler, Mark, Little, Melissa H., Lash, Lawrence H. and Cooper, Matthew (2015). Evaluation of biomarkers for in vitro prediction of drug-induced nephrotoxicity: comparison of HK-2, immortalized human proximal tubule epithelial, and primary cultures of human proximal tubular cells. Pharmacology Research and Perspectives, 3 (3) e00148, e00148. doi: 10.1002/prp2.148
Coll, Rebecca C., Robertson, Avril A. B., Chae, Jae Jin, Higgins, Sarah C., Muñoz-Planillo, Raúl, Inserra, Marco C., Vetter, Irina, Dungan, Lara S., Monks, Brian G., Stütz, Andrea, Croker, Daniel E., Butler, Mark S., Haneklaus, Moritz, Sutton, Caroline E., Núñez, Gabriel, Latz, Eicke, Kästner, Daniel L., Mills, Kingston H. G., Masters, Seth L., Schroder, Kate, Cooper, Matthew A. and O'Neill, Luke A. J. (2015). A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases. Nature Medicine, 21 (3), 248-257. doi: 10.1038/nm.3806
Rho, Jung-Rae, Subramaniam, Gurusamy, Choi, Hyukjae, Kim, Eun-Hee, Ng, Sok Peng, Yoganathan, K., Ng, Siewbee, Buss, Antony D., Butler, Mark S. and Gerwick, William H. (2015). Gargantulide A, a complex 52-membered macrolactone showing antibacterial activity from streptomyces sp.. Organic Letters, 17 (6), 1377-1380. doi: 10.1021/acs.orglett.5b00068
Rahim, Nusaibah Abdul, Cheah, Soon-Ee, Johnson, Matthew D., Yu, Heidi, Sidjabat, Hanna E., Boyce, John, Butler, Mark S., Cooper, Matthew A., Fu, Jing, Paterson, David L., Nation, Roger L., Bergen, Phillip J., Velkov, Tony and Li, Jian (2015). Synergistic killing of NDM-producing MDR Klebsiella pneumoniae by two ‘old’ antibiotics—polymyxin B and chloramphenicol. Journal of Antimicrobial Chemotherapy, 70 (9), 2589-2597. doi: 10.1093/jac/dkv135
Hickey, Shane M., Ashton, Trent D., White, Jonathan M., Li, Jian, Nation, Roger L., Yu, Heidi Y., Elliott, Alysha G., Butler, Mark S., Huang, Johnny X., Cooper, Matthew A. and Pfeffer, Frederick M. (2015). Synthesis of norbornane bisether antibiotics via silver-mediated alkylation. Rsc Advances, 5 (36), 28582-28596. doi: 10.1039/c5ra03321g
Cheng, Mu, Huang, Johnny Xiao, Ramu, Soumya, Butler, Mark S. and Cooper, Matthew A. (2014). Ramoplanin at bactericidal concentrations induces bacterial membrane depolarization in Staphylococcus aureus. Antimicrobial Agents and Chemotherapy, 58 (11), 6819-6827. doi: 10.1128/AAC.00061-14
Butler, Mark S., Robertson, Avril A. B. and Cooper, Matthew A. (2014). Natural product and natural product derived drugs in clinical trials. Natural Product Reports, 31 (11), 1612-1661. doi: 10.1039/c4np00064a
Butler, Mark S., Hansford, Karl A., Blaskovich, Mark A. T., Halai, Reena and Cooper, Matthew A. (2014). Glycopeptide antibiotics: back to the future. Journal of Antibiotics, 67 (9), 631-644. doi: 10.1038/ja.2014.111
Phetsang, Wanida, Blaskovich, Mark A. T., Butler, Mark S., Huang, Johnny Xiao, Zuegg, Johannes, Mamidyala, Sreeman K., Ramu, Soumya, Kavanagh, Angela M. and Cooper, Matthew A. (2014). An azido-oxazolidinone antibiotic for live bacterial cell imaging and generation of antibiotic variants. Bioorganic and Medicinal Chemistry, 22 (16), 4490-4498. doi: 10.1016/j.bmc.2014.05.054
Cheng, Mu, Ziora, Zyta M., Hansford, Karl A., Blaskovich, Mark A., Butler, Mark S. and Cooper, Matthew A. (2014). Anti-cooperative ligand binding and dimerisation in the glycopeptide antibiotic dalbavancin. Organic and Biomolecular Chemistry, 12 (16), 2568-2575. doi: 10.1039/c3ob42428f
Kotturi, Santosh R., Somanadhan, Brinda, Ch'Ng, Jun-Hong, Tan, Kevin S.-W., Butler, Mark S. and Lear, Martin J. (2014). Diverted total synthesis of falcitidin acyl tetrapeptides as new antimalarial leads. Tetrahedron Letters, 55 (11), 1949-1951. doi: 10.1016/j.tetlet.2014.02.008
Butler, Mark S., Towerzey, Leanne, Pham, Ngoc B., Hyde, Edward, Wadi, Sao Khemar, Guymer, Gordon P. and Quinn, Ronald J. (2014). Cardenolide Glycosides from Elaeodendron australe var. integrifolium. Phytochemistry, 98, 160-163. doi: 10.1016/j.phytochem.2013.11.024
Butler, Mark S., Fontaine, Frank and Cooper, Matthew A. (2014). Natural product libraries: Assembly, maintenance, and screening. Planta Medica, 80 (14), 1161-1170. doi: 10.1055/s-0033-1360109
Butler, Mark S. (2013). Remediating cancer via splicing modulation. Journal of Medicinal Chemistry, 56 (17), 6573-6575. doi: 10.1021/jm401289z
Butler, Mark S., Blaskovich, Mark A. and Cooper, Matthew A. (2013). Antibiotics in the clinical pipeline in 2013. Journal of Antibiotics, 66 (10), 571-591. doi: 10.1038/ja.2013.86
Velkov, Tony, Deris, Zakuan Z., Huang, Johnny X., Azad, Mohammad A. K., Butler, Mark, Sivanesan, Sivashangarie, Kiminskas, Lisa M., Dong, Yao-Da, Boyd, Ben, Baker, Mark A., Cooper, Matthew A., Nation, Roger L. and Li, Jian (2013). Surface changes and polymyxin interactions with a resistant strain of Klebsiella pneumoniae. Innate Immunity, 20 (4), 350-363. doi: 10.1177/1753425913493337
Coll, R. C., Robertson, A. A.B., Butler, M., Cooper, M. and O'Neill, L. A.J. (2013). Erratum: The cytokine release inhibitory drug CRID3 targets ASC oligomerisation in the NLRP3 and AIM2 inflammasomes. PLoS ONE, 8 (7) e29539. doi: 10.1371/annotation/78d328b9-2c8c-4978-84b1-7e6a0b12ada1
Somanadhan, Brinda, Kotturi, Santosh R., Leong, Chung Yan, Glover, Robert P., Huang, Yicun, Flotow, Horst, Buss, Antony D., Lear, Martin J. and Butler, Mark S. (2013). Isolation and synthesis of falcitidin, a novel myxobacterial-derived acyltetrapeptide with activity against the malaria target falcipain-2. Journal of Antibiotics, 66 (5), 259-264. doi: 10.1038/ja.2012.123
Ranall, Max V., Butler, Mark S., Blaskovich, Mark A. and Cooper, Matthew A. (2012). Resolving biofilm infections: current therapy and drug discovery strategies. Current Drug Targets, 13 (11), 1375-1385. doi: 10.2174/138945012803530251
Ghosh, Shibaji K., Butler, Mark S. and Lear, Martin J. (2012). Synthesis of 2-C-methylerythritols and 2-C-methylthreitols via enantiodivergent Sharpless dihydroxylation of trisubstituted olefins. Tetrahedron Letters, 53 (22), 2706-2708. doi: 10.1016/j.tetlet.2012.03.071
Butler, Mark S., Yoganathan, Kanagasundaram, Buss, Antony D. and Ng, Siewbee (2012). Identification of aluminium dioxalate in fungal cultures grown on vermiculite. Journal of Antibiotics, 65 (5), 275-276. doi: 10.1038/ja.2012.15
Karoli, Tomislav, Mamidyala, Sreeman K., Zuegg, Johannes, Fry, Scott R., Tee, Ernest H. L., Bradford, Tanya A., Madala, Praveen K., Huang, Johnny X., Ramu, Soumya, Butler, Mark S. and Cooper, Matthew A. (2012). Structure aided design of chimeric antibiotics. Bioorganic & Medicinal Chemistry Letters, 22 (7), 2428-2433. doi: 10.1016/j.bmcl.2012.02.019
Ghosh, Shibaji K., Somanadhan, Brinda, Tan, Kevin S.-W., Butler, Mark S. and Lear, Martin J. (2012). Absolute configuration and total synthesis of a novel antimalarial lipopeptide by the de novo preparation of chiral nonproteinogenic amino acids. Organic Letters, 14 (6), 1560-1563. doi: 10.1021/ol300293a
Butler, Mark S. and Cooper, Matthew A. (2012). Screening strategies to identify new antibiotics. Current Drug Targets, 13 (3), 373-387. doi: 10.2174/138945012799424624
Coll, Rebecca C., Robertson, Avril, Butler, Mark, Cooper, Matthew and O'Neill, Luke A. J. (2011). The cytokine release inhibitory drug CRID3 targets ASC oligomerisation in the NLRP3 and AIM2 inflammasomes. PLoS ONE, 6 (12) e29539, e29539. doi: 10.1371/journal.pone.0029539
Somanadhan, Brinda, Leong, Chungyan, Whitton, Stephen R., Ng, Siewbee, Buss, Antony D. and Butler, Mark S (2011). Identification of a naturally occurring quinazolin-4(3H)-one luciferase inhibitor. Journal of Natural Products, 74 (6), 1500-1502. doi: 10.1021/np1006179
Butler, Mark S. and Cooper, Matthew A. (2011). Antibiotics in the clinical pipeline in 2011. Journal of Antibiotics, 64 (6), 413-425. doi: 10.1038/ja.2011.44
Nguyen, Tuan Minh, Vu, Nguyen Quang, Youte, Jean-Jacques, Lau, Jacelyn, Chong, Angie, Ho, Ying San, Tan, Benjamin S. W., Yoganathan. K., Butler, Mark S. and Chai, Christina L. L. (2010). A fast and straightforward route towards the synthesis of the lissoclimide class of anti-tumour agents. Tetrahedron, 66 (47), 9270-9276. doi: 10.1016/j.tet.2010.09.031
Tee, Ernest H. L., Tomislav Karoli,, Ramu, Soumya, Huang, Johnny X., Butler, Mark S. and Cooper, Matthew A. (2010). Synthesis of Essramycin and Comparison of Its Antibacterial Activity. Journal of Natural Products, 73 (11), 1940-1942. doi: 10.1021/np100648q
Subramaniam, G., Ang, Kenny K. H., Ng, Siewbee, Buss, Antony D. and Butler, Mark S. (2009). A Benzopyrroloisoquinoline Alkaloid from Ficus fistulosa. Phytochemistry Letters, 2 (2), 88-90. doi: 10.1016/j.phytol.2008.12.006
Yoganathan, K., Cao, Shugeng, Crasta, Sharon C., Aitipamula, Srinivasulu, Whitton, Stephen R., Ng, Siewbee, Buss, Antony D. and Butler, Mark S. (2008). Microsphaerins A–D, four novel benzophenone dimers with activity against MRSA from the fungus Microsphaeropsis sp.. Tetrahedron, 64 (44), 10181-10187. doi: 10.1016/j.tet.2008.08.038
Butler, Mark S. and Newman, David J. (2008). Mother Nature's gifts to diseases of man: The impact of natural products on anti-infective, anticholestemics and anticancer drug discovery. Progress in Drug Research, 65, 2-44. doi: 10.1007/978-3-7643-8117-2_1
Butler, Mark S. (2008). Natural products to drugs: Natural product-derived compounds in clinical trials. Natural Product Reports, 25 (3), 475-516. doi: 10.1039/b514294f
Butler, Mark S. (2006). Erratum: Natural products to drugs: Natural product derived compounds in clinical trials (Natural Product Reports (2005) 22, (162-195) DOI: 10.1039/b402985m). Natural Product Reports, 23 (1) doi: 10.1039/b600890a
Cao, Shugeng, Low, Kia-Ngee, Glover, Robert P., Crasta, Sharon C., Ng, Siewbee, Buss, Antony D. and Butler, Mark S. (2006). Sundaicumones A and B, polyprenylated acylphloroglucinol derivatives from Calophyllum sundaicum with weak activity against the glucocorticoid receptor. Journal of Natural Products, 69 (4), 707-709. doi: 10.1021/np050528n
Butler, Mark S. and Buss, Antony D. (2006). Natural products — The future scaffolds for novel antibiotics?. Biochemical Pharmacology, 71 (7), 919-929. doi: 10.1016/j.bcp.2005.10.012
Butler, Mark S. (2006). Erratum: The role of natural product chemistry in drug discovery (Journal of Natural Products (2004) 67 (2142-2149)). Journal of Natural Products, 69 (1), 172-172. doi: 10.1021/np058132z
Yang, Lay Kien, Ng, Sok Peng, Flotow, Horst, Yoganathan, K., Daramola, B. O., Soejarto, D. Doel, Buss, Antony D. and Butler, Mark S. (2005). Pyrrole carboxamidine tryptase inhibitors from leptonychia pubescens. Planta Medica, 71 (11), 1071-1072. doi: 10.1055/s-2005-873111
Glover, Robert P., Yoganathan, K. and Butler, Mark S. (2005). NMR spectral assignments of three aspidofractinine alkaloids, kopsine, fruticosine and fruticosamine. Magnetic Resonance in Chemistry, 43 (6), 483-486. doi: 10.1002/mrc.1580
Yap, Sook Peng, Shen, Ping, Butler, Mark S., Gong, Yinhan, Loy, Chong Jin and Yong, Eu Leong (2005). New estrogenic prenylflavone from Epimedium brevicornum inhibits the growth of breast cancer cells. Planta Medica, 71 (2), 114-119. doi: 10.1055/s-2005-837776
Butler, Mark S. (2005). Natural products to drugs: Natural product derived compounds in clinical trials. Natural Product Reports, 22 (2), 162-195. doi: 10.1039/b402985m
Phoon, Chee Wee, Somanadhan, Brinda, Heng, Sabrina Cher Hui, Ngo, Anna, Ng, Siew Bee, Butler, Mark S., Buss, Antony D. and Sim, Mui Mui (2004). Isolation and total synthesis of gymnastatin N, a POLO-like kinase 1 active constituent from the fungus Arachniotus punctatus. Tetrahedron, 60 (50), 11619-11628. doi: 10.1016/j.tet.2004.09.046
Yoganathan, K., Rossant, Christine, Glover, Robert P., Cao, Shugeng, Vittal, Jagadese J., Ng, Siewbee, Huang, Yicun, Buss, Antony D. and Butler, Mark S. (2004). Inhibition of the human chemokine receptor CCR5 by variecolin and variecolol and isolation of four new variecolin analogues, emericolins A−D, from Emericella aurantiobrunnea. Journal of Natural Products, 67 (10), 1681-1684. doi: 10.1021/np049844c
Buss, Antony D. and Butler, Mark S. (2004). A new model for utilising chemical diversity from natural sources. Drug Development Research, 62 (4), 362-370. doi: 10.1002/ddr.10389
Yang, L. K., Glover, R. P., Yoganathan, K., Sarnaik, J. P., Godbole, A. J., Soejarto, D. D., Buss, A. D. and Butler, M. S. (2004). Ancisheynine, a novel naphthylisoquinolinium alkaloid from Ancistrocladus heyneanus. Tetrahedron Letters, 44 (31), 5827-5829. doi: 10.1016/S0040-4039(03)01397-2
Yoganathan, K., Yang, Lay-Kien, Rossant, Christine, Huang, Yicun, Ng, Siewbee, Butler, Mark S. and Buss, Antony D. (2004). Cochlioquinones and epi-cochlioquinones: Antagonists of the human chemokine receptor CCR5 from Bipolaris brizae and Stachybotrys chartarum. Journal of Antibiotics, 57 (1), 59-63. doi: 10.7164/antibiotics.57.59
Cao, Shugeng, Rossant, Christine, Ng, Siewbee, Buss, Antony D. and Butler, Mark S. (2003). Phenolic derivatives from Wigandia urens with weak activity against the chemokine receptor CCR5. Phytochemistry, 64 (5), 987-990. doi: 10.1016/S0031-9422(03)00448-5
Chan, Shing-Leng, Lee, Mei Chin, Tan, Kuan Onn, Yang, Lay-Kien, Lee, Alex S. Y., Flotow, Horst, Fu, Nai Yang, Butler, Mark S., Soejarto, Doel D., Buss, Antony D. and Yu, Victor C. (2003). Identification of chelerythrine as an inhibitor of BclXL function. Journal of Biological Chemistry, 278 (23), 20453-20456. doi: 10.1074/jbc.C300138200
Yoganathan, K., Rossant, Christine, Ng, Siewbee, Huang, Yicun, Butler, Mark S. and Buss, Antony D. (2003). 10-Methoxydihydrofuscin, fuscinarin, and fuscin, novel antagonists of the human CCR5 receptor from Oidiodendron griseum. Journal of Natural Products, 66 (8), 1116-1117. doi: 10.1021/np030146m
Appleton, D. R., Buss, Antony D. and Butler, Mark S. (2003). A simple method for high-throughput extract prefractionation for biological screening. Chimia, 61 (6), 327-331. doi: 10.2533/chimia.2007.327
Cao, Shugeng, Butler, Mark S. and Buss, Antony D. (2003). Flavonoids from Artocarpus Lanceifolius. Natural Product Research, 17 (2), 79-81. doi: 10.1080/1478641031000103641
Nilar, Sidebottom, PJ, Carte, BK and Butler, MS (2002). Three new pyridoacridine type alkaloids from a Singaporean ascidian. Journal of Natural Products, 65 (8), 1198-1200. doi: 10.1021/np010629v
Pham, NB, Butler, MS and Quinn, RJ (2002). Naturally occurring cembranes from an Australian Sarcophyton species. Journal of Natural Products, 65 (8), 1147-1150. doi: 10.1021/np010521f
Cao, SG, Lee, ASY, Huang, YC, Flotow, H, Ng, S, Butler, MS and Buss, AD (2002). Agonodepsides A and B: Two new depsides from a filamentous fungus F7524. Journal of Natural Products, 65 (7), 1037-1038. doi: 10.1021/np010626i
Ovenden, Spb, Cao, SG, Leong, C, Flotow, H, Gupta, MP, Buss, AD and Butler, MS (2002). Spermine alkaloids from Albizia adinocephala with activity against Plasmodium falciparum plasmepsin II. Phytochemistry, 60 (2), 175-177. doi: 10.1016/S0031-9422(02)00081-X
Yang, LK, Khoo-Beattie, C, Goh, KL, Chng, BL, Yoganathan, K, Lai, YH and Butler, MS (2001). Ardisiaquinones from Ardisia teysmanniana. Phytochemistry, 58 (8), 1235-1238. doi: 10.1016/S0031-9422(01)00317-X
Ovenden, Spb, Yew, ALS, Glover, RP, Ng, S, Rossant, CJ, Regalado, JC, Soejarto, DD, Buss, AD and Butler, MS (2001). Actephilol A and epiactephilol A: two novel aromatic terpenoids isolated from Actephila excelsa. Tetrahedron Letters, 42 (43), 7695-7697. doi: 10.1016/S0040-4039(01)01628-8
Dai, JR, Carte, BK, Sidebottom, PJ, Yew, ALS, Ng, SB, Huang, YC and Butler, MS (2001). Circumdatin G, a new alkaloid from the fungus Aspergillus ochraceus. Journal of Natural Products, 64 (1), 125-126. doi: 10.1021/np000381u
Butler, MS, Katavic, PL, Davis, RA, Forster, PI, Guymer, GP and Quinn, RJ (2000). 10-hydroxydarlingine, a new tropane alkaloid from the Australian proteaceous plant Triunia erythrocarpa. Journal of Natural Products, 63 (5), 688-689. doi: 10.1021/np9906065
Pham, NB, Butler, MS and Quinn, RJ (2000). Isolation of psammaplin A 11 '-sulfate and bisaprasin 11 '-sulfate from the marine sponge Aplysinella rhax. Journal of Natural Products, 63 (3), 393-395. doi: 10.1021/np990335y
Pham, NB, Butler, MS, Healy, PC and Quinn, RJ (2000). Anthoptilides A-E, new briarane diterpenes from the Australian sea pen Anthoptilum cf. kukenthali. Journal of Natural Products, 63 (3), 318-321. doi: 10.1021/np9903806
Katavic, PL, Butler, MS, Quinn, RJ, Forster, PI and Guymer, GP (1999). Tropane alkaloids from Darlingia darlingiana. Phytochemistry, 52 (3), 529-531. doi: 10.1016/S0031-9422(99)00263-0
Pham, NB, Butler, MS, Hooper, JNA, Moni, RW and Quinn, RJ (1999). Isolation of xestosterol esters of brominated acetylenic fatty acids from the marine sponge Xestospongia testudinaria. Journal of Natural Products, 62 (10), 1439-1442. doi: 10.1021/np9901635
Kalaitzis, JA, Leone, PD, Harris, L, Butler, MS, Ngo, A, Hooper, JNA and Quinn, RJ (1999). Adociasalfates 1, 7, and 8: New bioactive hexaprenoid hydroquinones from the marine sponge Adocia sp.. Journal of Organic Chemistry, 64 (15), 5571-5574. doi: 10.1021/jo990404d
Butler, MS, Katavic, PL, Forster, PI and Guymer, GP (1999). Two new naphthoquinones from the roots of Conospermum sphacelatum. Australian Journal of Chemistry, 52 (8), 813-815. doi: 10.1071/CH99041
Capon, Robert J., Rooney, Francis, Murray, Leanne M., Collins, Elizabeth, Sim, Alistair T. R., Rostas, John A. P., Butler, Mark S. and Carroll, Anthony R. (1998). Dragmacidins: New protein phosphatase inhibitors from a southern Australian deep-water marine sponge, Spongosorites sp.. Journal of Natural Products, 61 (5), 660-662. doi: 10.1021/np970483t
Pettit, GR, Butler, MS, Williams, MD, Filiatrault, MJ and Pettit, RK (1996). Isolation and structure of hemibastadinols 1-3 from the Papua New Guinea marine sponge Ianthella basta. Journal of Natural Products, 59 (10), 927-934. doi: 10.1021/np960249n
Pettit, GR, Butler, MS, Bass, CG, Doubek, DL, Williams, MD, Schmidt, JM, Pettit, RK, Hooper, Jna, Tackett, LP and Filiatrault, MJ (1995). Antineoplastic Agents .326. the Stereochemistry of Bastadin-8, Bastadin-10, and Bastadin-12 From the Bismarck Archipelago Marine Sponge Ianthella-Basta. Journal of Natural Products-Lloydia, 58 (5), 680-688. doi: 10.1021/np50119a005
Johns, RB, Brady, BA, Butler, MS, Dembitsky, VM and Smith, JD (1994). Organic Geochemical and Geochemical Studies of Inner Great-Barrier-Reef Sediments .4. Identification of Terrigenous and Marine Sourced Inputs. Organic Geochemistry, 21 (10-11), 1027-1035. doi: 10.1016/0146-6380(94)90066-3
Urban, S, Butler, MS and Capon, RJ (1994). Lamellarins-O and Lamellarin-P - New Aromatic Metabolites From the Australian Marine Sponge Dendrilla-Cactos. Australian Journal of Chemistry, 47 (10), 1919-1924. doi: 10.1071/CH9941919
Capon, RJ, Elsbury, K, Butler, MS, Lu, CC, Hooper, Jna, Rostas, Jap, Obrien, KJ, Mudge, LM and Sim, Atr (1993). Extraordinary Levels of Cadmium and Zinc in a Marine Sponge, Tedania-Charcoti Topsent - Inorganic Chemical Defense Agents. Experientia, 49 (3), 263-264. doi: 10.1007/BF01923536
Butler, MS and Capon, RJ (1993). Beyond Polygodial - New Drimane Sesquiterpenes From a Southern Australian Marine Sponge, Dysidea Sp. Australian Journal of Chemistry, 46 (8), 1255-1267. doi: 10.1071/CH9931255
Butler, MS and Capon, RJ (1993). Trunculin-F and Contrunculin-A and Contrunculin-B - Novel Oxygenated Norterpenes From a Southern Australian Marine Sponge, Latrunculia-Conulosa. Australian Journal of Chemistry, 46 (9), 1363-1374. doi: 10.1071/CH9931363
Butler, MS and Capon, RJ (1992). The Luffarins (a-Z), Novel Terpenes From An Australian Marine Sponge, Luffariella-Geometrica. Australian Journal of Chemistry, 45 (10), 1705-1743. doi: 10.1071/CH9921705
Butler, MS, Capon, RJ and Lu, CC (1992). Psammopemmins (a-C), Novel Brominated 4-Hydroxyindole Alkaloids From An Antarctic Sponge, Psammopemma Sp. Australian Journal of Chemistry, 45 (11), 1871-1877. doi: 10.1071/CH9921871
Butler, Mark S. and Capon, Robert J. (1992). Conulosins (A and B): Novel norsesterterpene acids from an australian marine sponge, latrunculia conulosa. Natural Product Letters, 1 (3), 171-178. doi: 10.1080/10575639208048908
Butler, MS, Capon, RJ, Nadeson, R and Beveridge, AA (1991). Aromatic Bisabolenes From An Australian Marine Sponge, Arenochalina Sp. Journal of Natural Products, 54 (2), 619-623. doi: 10.1021/np50074a048
Butler, MS and Capon, RJ (1991). Norterpene Dienes From An Australian Marine Sponge Latrunculia-Brevis. Australian Journal of Chemistry, 44 (1), 77-85. doi: 10.1071/CH9910077
Butler, MS, Lim, TK, Capon, RJ and Hammond, LS (1991). The Bastadins Revisited - New Chemistry From the Australian Marine Sponge Ianthella-Basta. Australian Journal of Chemistry, 44 (2), 287-296. doi: 10.1071/CH9910287
Conference Papers
Kammoun, H. L., Allen, T. L., Henstridge, D. C., Barre, S., Coll, R. C., Butler, M. S., Roberston, A. A. B., O'Neill, L. A., Murphy, A. J., Cooper, M. A. and Febbraio, M. A. (2016). Evidence against a role for NLRP3-driven inflammation in the db/db mouse model of type 2 diabetes. International Congress of Immunology (ICI), Melbourne, VIC, Australia, 21-26 August 2016. Weinheim, Germany: Wiley - VCH Verlag. doi: 10.1002/eji.201670200
Butler, M. S. (2015). Natural products in clinical trials: Current state of play and future directions. Annual Meeting of the American Society of Pharmacognosy, Copper Mountain, Colorado, USA, Jul 25-29, 2015. Stuttgart, Germany: Georg Thieme Verlag. doi: 10.1055/s-005-29385
Gong, Y., Muldoon, C. A., Premraj, R., Ziora, Z. M., Bradford, T. A., Cheng, M., Ramu, S., Huang, J. X., Kavanagh, A., Pelingon, R., Lee, J. C., Wong, K., Butler, M. S., Blaskovich, M. A. and Cooper, M. A. (2012). New glycopeptidic antibiotics to combat multidrug resistant pathogens. 32nd European Peptide Symposium, Athens, Greece, 2-7 September 2012. Chichester, West Sussex, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.2449
Ghosh, S. K., Somanadhan, B., Butler, M. S. and Lear, M. J. (2010). Amino acid stereochemical assignment and total synthesis of a natural anti-malarial peptide. unknown, unknown, unknown. WASHINGTON: AMER CHEMICAL SOC.
Butler, Mark S. (2004). The role of natural product chemistry in drug discovery. Cincinnati, OH, U.S.A.: American Chemical Society. doi: 10.1021/np040106y