Dr Jilong Qin
Research Fellow
Institute for Molecular Bioscience
Publications
Journal Articles
Hong, Yaoqin, Qin, Jilong and Totsika, Makrina (2025). Not too rigid nor too wobbly: defining an optimal membrane fluidity range essential for biofilm formation in Escherichia coli. mLife, 4 (4), 461-464. doi: 10.1002/mlf2.70024
Hong, Yaoqin, Qin, Jilong, Doyle, Matthew Thomas and Reeves, Peter Richard (2025). Sequestration of dead-end undecaprenyl phosphate-linked oligosaccharide intermediate. Microbiology, 171 (1) 001530. doi: 10.1099/mic.0.001530
Qin, Jilong, Hong, Yaoqin, Maczuga, Nicholas T., Morona, Renato and Totsika, Makrina (2025). Tolerance mechanisms in polysaccharide biosynthesis: implications for undecaprenol phosphate recycling in Escherichia coli and Shigella flexneri. PLOS Genetics, 21 (1) e1011591, 1. doi: 10.1371/journal.pgen.1011591
Hong, Yaoqin, Qin, Jilong, Mitchell, Lachlan, Paxman, Jason J., Heras, Begoña and Totsika, Makrina (2024). Bacterial suppressor-of-copper-sensitivity proteins exhibit diverse thiol-disulfide oxidoreductase cellular functions. iScience, 27 (12) 111392, 111392. doi: 10.1016/j.isci.2024.111392
Qin, Jilong, Hong, Yaoqin and Totsika, Makrina (2024). Determining glycosyltransferase functional order via lethality due to accumulated O-antigen intermediates, exemplified with Shigella flexneri O-antigen biosynthesis. Applied and Environmental Microbiology, 90 (6) e02203-23, 6. doi: 10.1128/aem.02203-23
Hong, Yaoqin, Qin, Jilong and Totsika, Makrina (2023). A conditional nature for the synthetical lethality between defects in lipid and peptidoglycan biosynthesis. Proceedings of the National Academy of Sciences, 120 (52) e2318882120. doi: 10.1073/pnas.2318882120
Ndukwe, Audrey R. N., Qin, Jilong, Wiedbrauk, Sandra, Boase, Nathan R. B., Fairfull-Smith, Kathryn E. and Totsika, Makrina (2023). In vitro activities of oxazolidinone antibiotics alone and in combination with C-TEMPO against methicillin-resistant Staphylococcus aureus biofilms. Antibiotics, 12 (12) 1706, 1706. doi: 10.3390/antibiotics12121706
Qin, Jilong, Hong, Yaoqin, Morona, Renato and Totsika, Makrina (2023). O antigen biogenesis sensitises Escherichia coli K-12 to bile salts, providing a plausible explanation for its evolutionary loss. PLOS Genetics, 19 (10) e1010996. doi: 10.1371/journal.pgen.1010996
Hawas, Sophia, Qin, Jilong, Wiedbrauk, Sandra, Fairfull-Smith, Kathryn and Totsika, Makrina (2023). Preclinical evaluation of nitroxide-functionalised ciprofloxacin as a novel antibiofilm drug hybrid for urinary tract infections. Antibiotics, 12 (10) 1479, 1479. doi: 10.3390/antibiotics12101479
Hong, Yaoqin, Qin, Jilong, Forga, Xavier Bertran and Totsika, Makrina (2023). Extensive diversity in Escherichia coli group 3 capsules is driven by recombination and plasmid transfer from multiple species. Microbiology Spectrum, 11 (4) e01432-23. doi: 10.1128/spectrum.01432-23
Ndukwe, Audrey R. N., Hawas, Sophia, Qin, Jilong, Wiedbrauk, Sandra, Totsika, Makrina, Boase, Nathan R. B. and Fairfull-Smith, Kathryn E. (2023). Simple and efficient synthesis of 3-aryl-2-oxazolidinone scaffolds enabling increased potency toward biofilms. Molecular Pharmaceutics, 20 (7), 3484-3493. doi: 10.1021/acs.molpharmaceut.3c00095
Hong, Yaoqin, Qin, Jilong, Verderosa, Anthony D., Hawas, Sophia, Zhang, Bing, Blaskovich, Mark A. T., Cronan, John E. and Totsika, Makrina (2022). Loss of β-ketoacyl acyl carrier protein synthase III activity restores multidrug-resistant escherichia coli sensitivity to previously ineffective antibiotics. mSphere, 7 (3), e0011722. doi: 10.1128/msphere.00117-22
Ren, Jiongyu, Murray, Rebecca, Wong, Cynthia S., Qin, Jilong, Chen, Michael, Totsika, Makrina, Riddell, Andrew D., Warwick, Andrea, Rukin, Nicholas and Woodruff, Maria A. (2022). Development of 3D printed biodegradable mesh with antimicrobial properties for pelvic organ prolapse. Polymers, 14 (4) 763, 763. doi: 10.3390/polym14040763