Dr Eric Wu
Research Fellow
Institute for Molecular Bioscience
Researcher biography
Research interests in Artificial Heart and Lung therapies.
Charted Engineering (Biomedical) with Engineers Australia and BPEQ. Industry experience in nonclinical device testing and regulatory submissions of total artificial heart.
Engineering Lead at Innovative Cardiovascular Engineering and Technology Laboratory (ICETLab), Critical Care Research Group, The Prince Charles Hospital
Book Chapters
Wu, Eric L. and Stevens, Michael C. (2025). Ventricular assist devices: volume displacement pumps. Mechanical Circulatory and Respiratory Support. (pp. 123-144) London, United Kingdom: Academic Press. doi: 10.1016/b978-0-443-22148-4.00004-6
Heinsar, Silver, Wu, Eric L., Ajamu, Samuel and Ündar, Akif (2025). Pulsatile versus continuous flow. Mechanical Circulatory and Respiratory Support. (pp. 517-551) London, United Kingdom: Academic Press. doi: 10.1016/b978-0-443-22148-4.00017-4
Wu, Eric L., Stevens, Michael C., Pauls, Jo P. and Steinseifer, Ulrich (2018). First-generation ventricular assist devices. Mechanical circulatory and respiratory support. (pp. 93-115) edited by Shaun D. Gregory, Michael C. Stevens and John F. Fraser. London, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-810491-0.00003-5
Wu, Eric L., Kleinheyer, Matthias and Undar, Akif (2018). Pulsatile vs. continuous flow. Mechanical circulatory and respiratory support. (pp. 379-406) edited by Shaun D. Gregory, Michael C. Stevens and John F. Fraser. London, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-810491-0.00012-6
Journal Articles
Mcna Mee, Antony P., Timms, Daniel, Nestler, Frank, Bartnikowski, Nicole, Tansley, Geoff D., Wu, Eric and Simmonds, Michael J. (2025). In Vitro Hemocompatibility of the BiVACOR Total Artificial Heart Near the Boundaries of Clinical Operation. ASAIO Journal 10.1097/MAT.0000000000002536. doi: 10.1097/MAT.0000000000002536
Wu, Eric L., Maw, Martin, Stephens, Andrew F., Stevens, Michael C., Fraser, John F., Tansley, Geoffrey, Moscato, Francesco and Gregory, Shaun D. (2023). Estimation of left ventricular stroke work for rotary left ventricular assist devices. ASAIO Journal, 69 (9), 817-826. doi: 10.1097/MAT.0000000000001972
Heinsar, Silver, Bartnikowski, Nicole, Hartel, Gunter, Farah, Samia M., Seah, E‐Peng, Wu, Eric, Colombo, Sebastiano Maria, Semenzin, Clayton, Haymet, Andrew, Rätsep, Indrek, Pauls, Jo, Fraser, John F. and Suen, Jacky Y. (2023). A comprehensive evaluation of hemodynamic energy production and circuit loss using four different ECMO arterial cannulae. Artificial Organs, 47 (7), 1122-1132. doi: 10.1111/aor.14523
Semenzin, Clayton S, Mapley, Martin, Wu, Eric, Pauls, Jo P, Simpson, Benjamin, Gregory, Shaun D and Tansley, Geoff (2020). Open-source automated centrifugal pump test rig. HardwareX, 8 e00140, e00140. doi: 10.1016/j.ohx.2020.e00140
Stephens, Andrew F., Mapley, Martin, Wu, Eric L., Fraser, John F., Steinseifer, Ulrich, Bartnikowski, Nicole and Gregory, Shaun D. (2020). HeartWare HVAD flow estimator accuracy for left and right ventricular support. ASAIO Journal, 67 (4), 416-422. doi: 10.1097/MAT.0000000000001247
Wu, Eric L., Fresiello, Libera, Kleinhyer, Matthias, Meyns, Bart, Fraser, John F., Tansley, Geoff and Gregory, Shaun D. (2020). Haemodynamic effect of left atrial and left ventricular cannulation with a rapid speed modulated rotary blood pump during rest and exercise: investigation in a numerical cardiorespiratory model. Cardiovascular engineering and technology, 11 (4), 350-361. doi: 10.1007/s13239-020-00471-1
Gregory, Shaun D., Pauls, Jo P., Wu, Eric L., Stephens, Andrew, Steinseifer, Ulrich, Tansley, Geoff and Fraser, John F. (2020). An advanced mock circulation loop for in vitro cardiovascular device evaluation. Artificial Organs, 44 (6) aor.13636, E238-E250. doi: 10.1111/aor.13636
Wu, Eric L., Stevens, Michael C., Nestler, Frank, Pauls, Jo P., Bradley, Andrew P., Tansley, Geoff, Fraser, John F. and Gregory, Shaun D. (2020). A Starling-like total work controller for rotary blood pumps: an in vitro evaluation. Artificial Organs, 44 (3), E40-E53. doi: 10.1111/aor.13570
Chan, Chris Hoi Houng, Nandakumar, Deepika, Balletti, Nicoletta, Horobin, Jarod, Wu, Eric Lee-Jan, Bouquet, Mahe, Stephens, Andrew, Pauls, Jo P., Tansley, Geoff, Fraser, John F., Simmonds, Michael J. and Gregory, Shaun D. (2019). In Vitro Hemocompatibility Evaluation of Modified Rotary Left to Right Ventricular Assist Devices in Pulmonary Flow Conditions. ASAIO Journal, 66 (6), 1-8. doi: 10.1097/mat.0000000000001049
Boone, Alice C., Gregory, Shaun D., Wu, Eric L., Stephens, Andrew, Liao, Sam, Pauls, Jo P., Salamonsen, Robert, Fraser, John and Tansley, Geoff D. (2019). Evaluation of an intraventricular balloon pump for short‐term support of patients with heart failure. Artificial Organs, 43 (9) aor.13454, 860-869. doi: 10.1111/aor.13454
Liao, Sam, Wu, Eric L., Neidlin, Michael, Li, Zhiyong, Simpson, Benjamin and Gregory, Shaun D. (2018). The influence of rotary blood pump speed modulation on the risk of intraventricular thrombosis. Artificial Organs, 42 (10), 943-953. doi: 10.1111/aor.13330
Wu, Eric L., Nestler, Frank, Kleinheyer, Matthias, Stevens, Michael C., Pauls, Jo P., Fraser, John F. and Gregory, Shaun D. (2018). Pulmonary valve opening with two rotary left ventricular assist devices for biventricular support. Artificial Organs, 42 (1), 31-40. doi: 10.1111/aor.12967
Gregory, Shaun D., Stevens, Michael C., Wu, Eric L., Pauls, Jo P., Kleinheyer, Matthias and Fraser, John F. (2016). Mitral valve regurgitation with a rotary left ventricular assist device: the haemodynamic effect of inlet cannulation site and speed modulation. Annals of Biomedical Engineering, 44 (9), 2674-2682. doi: 10.1007/s10439-016-1579-5
Conference Papers
Garbutt, Michael, Grant, Oriane, Nonaka, Hideaki, Bosch, Johannes, Benitez, Jessica, Fraser, John F. and Wu, Eric L. (2025). Evaluation of cardiac output estimation with veno-venous extracorporeal membrane oxygenation support: in vitro study. Piscataway, NJ United States: Institute of Electrical and Electronics Engineers. doi: 10.1109/EMBC58623.2025.11251892
Timms, Daniel, Greatrex, Nicholas, Nestler, Frank, Wu, Eric, Kleinheyer, Matthias, Gluck, Trenton, Elgalad, Abdelmotagaly, Costas, Gil, Shafii, Alexis E., Dowling, Robert, Cohn, William and Frazier, O.H. (2023). CARD5: chronic In-vivo evaluation of the BiVACOR rotary total artificial heart. ASAIO 2023 Annual Meeting, San Francisco, CA USA, 14-17 June 2023. Philadelphia, PA USA: Lippincott Williams & Wilkins. doi: 10.1097/01.mat.0000943544.23409.60
Timms, D. L., Greatrex, N., Nestler, F., Wu, E., Kleinheyer, M., Cohn, W. and Frazier, O. (2023). (127) Preclinical evaluation of the bivacor total artificial heart. ISHLT 43rd Annual Meeting and Scientific Sessions, Denver, CO USA, 19-22 April 2023. Philadelphia, PA USA: Elsevier. doi: 10.1016/j.healun.2023.02.143
Wu, Eric L., Tansley, Geoff, Fraser, John F. and Gregory, Shaun D. (2018). In-vitro evaluation of cardiac energetics and coronary flow with volume displacement and rotary blood pumps. 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018, Honolulu, Hawaii, 18-21 July 2018. NEW YORK: IEEE. doi: 10.1109/EMBC.2018.8513158