Dr Nhu Nguyen
Research Officer
Institute for Molecular Bioscience
+61 7 344 36266
Journal Articles
Lian, Zheng Jie, Phan, Minh-Duy, Hancock, Steven J., Nhu, Nguyen Thi Khanh, Paterson, David L. and Schembri, Mark A. (2023). Genetic basis of I-complex plasmid stability and conjugation. PLOS Genetics, 19 (6) e1010773, e1010773. doi: 10.1371/journal.pgen.1010773
Nhu, Nguyen Thi Khanh, Ravi, Chitra and Schembri, Mark A. (2023). Uropathogenic Escherichia coli biofilms. Microbiology Australia, 44 (2), 109-112. doi: 10.1071/ma23030
Mu, Andre, Klare, William P., Baines, Sarah L., Ignatius Pang, C. N., Guérillot, Romain, Harbison-Price, Nichaela, Keller, Nadia, Wilksch, Jonathan, Nhu, Nguyen Thi Khanh, Phan, Minh-Duy, Keller, Bernhard, Nijagal, Brunda, Tull, Dedreia, Dayalan, Saravanan, Chua, Hwa Huat Charlie, Skoneczny, Dominik, Koval, Jason, Hachani, Abderrahman, Shah, Anup D., Neha, Nitika, Jadhav, Snehal, Partridge, Sally R., Cork, Amanda J., Peters, Kate, Bertolla, Olivia, Brouwer, Stephan, Hancock, Steven J., Álvarez-Fraga, Laura, De Oliveira, David M. P. ... Walker, Mark J. (2023). Integrative omics identifies conserved and pathogen-specific responses of sepsis-causing bacteria. Nature Communications, 14 (1) 1530, 1-21. doi: 10.1038/s41467-023-37200-w
Hancock, Steven J., Lo, Alvin W., Ve, Thomas, Day, Christopher J., Tan, Lendl, Mendez, Alejandra A., Phan, Minh-Duy, Nhu, Nguyen Thi Khanh, Peters, Kate M., Richards, Amanda C., Fleming, Brittany A., Chang, Chyden, Ngu, Dalton H. Y., Forde, Brian M., Haselhorst, Thomas, Goh, Kelvin G. K., Beatson, Scott A., Jennings, Michael P., Mulvey, Matthew A., Kobe, Bostjan and Schembri, Mark A. (2022). Ucl fimbriae regulation and glycan receptor specificity contribute to gut colonisation by extra-intestinal pathogenic Escherichia coli. PLoS Pathogens , 18 (6) e1010582, e1010582. doi: 10.1371/journal.ppat.1010582
Schembri, Mark A., Nhu, Nguyen Thi Khanh and Phan, Minh-Duy (2022). Gut–bladder axis in recurrent UTI. Nature Microbiology, 7 (5), 601-602. doi: 10.1038/s41564-022-01113-z
Phan, Minh-Duy, Peters, Kate M., Alvarez Fraga, Laura, Wallis, Steven C., Hancock, Steven, Nhu, Nguyen Thi Khanh, Forde, Brian, Bauer, Michelle J., Paterson, David L., Beatson, Scott A, Lipman, Jeffrey and Schembri, Mark A. (2022). Plasmid-mediated ciprofloxacin resistance imparts a selective advantage on Escherichia coli ST131. Antimicrobial Agents and Chemotherapy, 66 (1) e02146-21, 1-11. doi: 10.1128/aac.02146-21
Alvarez-Fraga, Laura, Phan, Minh-Duy, Goh, Kelvin G. K., Nhu, Nguyen Thi Khanh, Hancock, Steven J., Allsopp, Luke P., Peters, Kate M., Forde, Brian M., Roberts, Leah W., Sullivan, Matthew J., Totsika, Makrina, Beatson, Scott A., Ulett, Glen C. and Schembri, Mark A. (2022). Differential Afa/Dr fimbriae expression in the multidrug-resistant Escherichia coli ST131 clone. mBio, 13 (1) e03519, e0351921. doi: 10.1128/mbio.03519-21
Murigneux, Valentine, Roberts, Leah W., Forde, Brian M., Phan, Minh-Duy, Nhu, Nguyen Thi Khanh, Irwin, Adam D., Harris, Patrick N. A., Paterson, David L., Schembri, Mark A., Whiley, David M. and Beatson, Scott A. (2021). MicroPIPE: validating an end-to-end workflow for high-quality complete bacterial genome construction. BMC Genomics, 22 (1) 474, 474. doi: 10.1186/s12864-021-07767-z
Hancock, Steven J., Phan, Minh-Duy, Luo, Zhenyao, Lo, Alvin W., Peters, Kate M., Nhu, Nguyen Thi Khanh, Forde, Brian M., Whitfield, Jason, Yang, Ji, Strugnell, Richard A., Paterson, David L., Walsh, Timothy R., Kobe, Bostjan, Beatson, Scott A. and Schembri, Mark A. (2020). Comprehensive analysis of IncC plasmid conjugation identifies a crucial role for the transcriptional regulator AcaB. Nature Microbiology, 5 (11), 1340-1348. doi: 10.1038/s41564-020-0775-0
Nhu, Nguyen Thi Khanh, Phan, Minh-Duy, Forde, Brian M., Murthy, Ambika M. V., Peters, Kate M., Day, Christopher J., Poole, Jessica, Kidd, Timothy J., Welch, Rodney A., Jennings, Michael P., Ulett, Glen C., Sweet, Matthew J., Beatson, Scott A. and Schembri, Mark A. (2019). Complex multilevel control of hemolysin production by uropathogenic Escherichia coli. mBio, 10 (5) e02248-19. doi: 10.1128/mbio.02248-19
Stocks, Claudia J., Phan, Minh-Duy, Achard, Maud E. S., Nhu, Nguyen Thi Khanh, Condon, Nicholas D., Gawthorne, Jayde A., Lo, Alvin W., Peters, Kate M., McEwan, Alastair G., Kapetanovic, Ronan, Schembri, Mark A. and Sweet, Matthew J. (2019). Uropathogenic Escherichia coli employs both evasion and resistance to subvert innate immune-mediated zinc toxicity for dissemination. Proceedings of the National Academy of Sciences, 116 (13), 6341-6350. doi: 10.1073/pnas.1820870116
Murthy, Ambika M. V., Sullivan, Matthew J., Nhu, Nguyen Thi Khanh, Lo, Alvin W., Phan, Minh-Duy, Peters, Kate M., Boucher, Dave, Schroder, Kate, Beatson, Scott A., Ulett, Glen C., Schembri, Mark A. and Sweet, Matthew J. (2019). Variation in hemolysin A expression between uropathogenic Escherichia coli isolates determines NLRP3-dependent vs. -independent macrophage cell death and host colonization. FASEB Journal : official publication of the Federation of American Societies for Experimental Biology, 33 (6), fj201802100R-7450. doi: 10.1096/fj.201802100R
Boinett, Christine J., Cain, Amy K., Hawkey, Jane, Nhu Tran Do Hoang,, Nhu, Nguyen Thi Khanh Nhu, Pham, Thanh Duy, Dordel, Janina, Campbell, James, Nguyen Phu Huong Lan,, Mayho, Matthew, Langridge, Gemma C., Hadfield, James, Nguyen Van Vinh Chau,, Thwaites, Guy E., Parkhill, Julian, Thomson, Nicholas R., Holt, Kathryn E. and Baker, Stephen (2019). Clinical and laboratory-induced colistin-resistance mechanisms in Acinetobacter baumannii. Microbial Genomics, 5 (2) 000246. doi: 10.1099/mgen.0.000246
Nhu, Nguyen Thi Khanh, Phan, Minh-Duy, Peters, Kate M., Lo, Alvin W., Forde, Brian M., Min Chong, Teik, Yin, Wai-Fong, Chan, Kok-Gan, Chromek, Milan, Brauner, Annelie, Chapman, Matthew R., Beatson, Scott A. and Schembri, Mark A. (2018). Discovery of new genes involved in curli production by a uropathogenic Escherichia coli strain from the highly virulent O45:K1:H7 lineage. mBio, 9 (4) e01462-18. doi: 10.1128/mbio.01462-18
Murthy, Ambika M. V., Phan, Minh-Duy, Peters, Kate M., Nhu, Nguyen Thi Khanh, Welch, Rodney A., Ulett, Glen C., Schembri, Mark A. and Sweet, Matthew J. (2018). Regulation of hemolysin in uropathogenic Escherichia coli fine-tunes killing of human macrophages. Virulence, 9 (1), 1-32. doi: 10.1080/21505594.2018.1465786
Phan, Minh-Duy, Nhu, Nguyen Thi Khanh, Achard, Maud E. S., Forde, Brian M., Hong, Kar Wai, Chong, Teik Min, Yin, Wai-Fong, Chan, Kok-Gan, West, Nicholas P., Walker, Mark J., Paterson, David L., Beatson, Scott A. and Schembri, Mark A. (2017). Modifications in the pmrB gene are the primary mechanism for the development of chromosomally encoded resistance to polymyxins in uropathogenic Escherichia coli. Journal of Antimicrobial Chemotherapy, 72 (10), 2729-2736. doi: 10.1093/jac/dkx204
Hassan, Karl A., Cain, Amy K., Huang, TaoTao, Liu, Qi, Elbourne, Liam D. H., Boinett, Christine J., Brzoska, Anthony J., Li, Liping, Ostrowski, Martin, Nhu, Nguyen Thi Khanh, Nhu, Tran Do Hoang, Baker, Stephen, Parkhill, Julian and Paulsen, Ian T. (2016). Fluorescence-based flow sorting in parallel with transposon insertion site sequencing identifies multidrug efflux systems in Acinetobacter baumannii. mBio, 7 (5) e01200-16. doi: 10.1128/mBio.01200-16
Ben Zakour, Nouri L, Alsheikh-Hussain, Areej S, Ashcroft, Melinda M, Khanh Nhu, Nguyen Thi, Roberts, Leah W, Stanton-Cook, Mitchell, Schembri, Mark A and Beatson, Scott A (2016). Erratum for Ben Zakour et al., Sequential Acquisition of Virulence and Fluoroquinolone Resistance Has Shaped the Evolution of Escherichia coli ST131. mBio, 7 (3), 1-1. doi: 10.1128/mBio.00958-16
Nhu, Nguyen Thi Khanh, Riordan, David W., Nhu, Tran Do Hoang, Thanh, Duy Pham, Thwaites, Guy, Lan, Nguyen Phu Huong, Wren, Brendan W., Baker, Stephen and Stabler, Richard A. (2016). The induction and identification of novel Colistin resistance mutations in Acinetobacter baumannii and their implications. Scientific Reports, 6 (1) 28291, 28291. doi: 10.1038/srep28291
Ben Zakour, Nouri L., Alsheikh-Hussain, Areej S., Ashcroft, Melinda M., Nhu, Nguyen Thi Khanh, Roberts, Leah W., Stanton-Cook, Mitchell, Schembri, Mark A. and Beatson, Scott A. (2016). Sequential acquisition of virulence and fluoroquinolone resistance has shaped the evolution of Escherichia coli ST131. MBio, 7 (2) e00347-16, e00347-16.1-e00347-16.11. doi: 10.1128/mBio.00347-16
Schultz, Mark B., Duy, Pham Thanh, Nhu, Tran Do Hoan, Wick, Ryan R., Ingle, Danielle J., Hawkey, Jane, Edwards, David J., Kenyon, Johanna J., Nguyen Phu Huong Lan,, Campbell, James I., Thwaites, Guy, Nguyen, Thi Khanh Nhu, Hall, Ruth M., Fournier-Level, Alexandre, Baker, Stephen and Holt, Kathryn E. (2016). Repeated local emergence of carbapenem-resistant Acinetobacter baumannii in a single hospital ward. Microbial Genomics, 2 (3), 1-15. doi: 10.1099/mgen.0.000050
Le Minh, Vien, Nhu, Nguyen Thi Khanh, Phat, Voong Vinh, Thompson, Corinne, Lan, Nguyen Phu Huong, Nga, Tran Vu Thieu, Tam, Pham Thi Thanh, Tuyen, Ha Thanh, Nhu, Tran Do Hoang, Van Hao, Nguyen, Loan, Huynh Thi, Yen, Lam Minh, Parry, Christopher M., Nghia, Ho Dang Trung, Campbell, James I., Hien, Tran Tinh, Thwaites, Louise, Thwaites, Guy, Van Vinh Chau, Nguyen and Baker, Stephen (2015). In vitro activity of colistin in antimicrobial combination against carbapenem-resistant acinetobacter baumannii isolated from patients with ventilator-associated pneumonia in Vietnam. Journal of Medical Microbiology, 64 (10), 1162-1169. doi: 10.1099/jmm.0.000137
Le, Vien., Nhu, Nguyen Thi Khanh., Cerdeno-Tarraga, Ana., Campbell, James I., Tuyen, Ha Thanh., Nhu, Tran Do Hoang., Tam, Pham Thi Thanh., Schultsz, Constance., Thwaites, Guy., Thomson, Nicholas R. and Baker, Stephen (2015). Genetic characterization of three qnrS1-harbouring multidrug-resistance plasmids and qnrS1-containing transposons circulating in Ho Chi Minh City, Vietnam. Journal of Medical Microbiology, 64 (8) 000100, 869-878. doi: 10.1099/jmm.0.000100
Holt, Kathryn E., Wertheim, Heiman, Zadoks, Ruth N., Baker, Stephen, Whitehouse, Chris A., Dance, David, Jenney, Adam, Connor, Thomas R., Hsu, Li Yang, Severin, Juliette, Brisse, Sylvain, Cao, Hanwei, Wilksch, Jonathan, Gorrie, Claire, Schultz, Mark B., Edwards, David J., Van Nguyen, Kinh, Nguyen, Trung Vu, Dao, Trinh Tuyet, Mensink, Martijn, Le Minh, Vien, Nhu, Nguyen Thi Khanh, Schultsz, Constance, Kuntaman K., Newton P.N., Moore C.E., Strugnell R.A. and Thomson N.R. (2015). Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health. Proceedings of the National Academy of Sciences of the United States of America, 112 (27), E3574-E3581. doi: 10.1073/pnas.1501049112
Beatson, Scott A., Ben Zakour, Nouri L., Totsika, Makrina, Forde, Brian M., Watts, Rebecca E., Mabbett, Amanda N., Szubert, Jan M., Sarkar, Sohinee, Phan, Minh-Duy, Peters, Kate M., Petty, Nicola K., Alikhan, Nabil-Fareed, Sullivan, Mitchell J., Gawthorne, Jayde A., Stanton-Cook, Mitchell, Nguyen Thi Khanh Nhu, Chong, Teik Min, Yin, Wai-Fong, Chan, Kok-Gan, Hancock, Viktoria, Ussery, David W., Ulett, Glen C. and Schembri, Mark A. (2015). Molecular analysis of asymptomatic bacteriuria Escherichia coli strain VR50 reveals adaptation to the urinary tract by gene acquisition. Infection and Immunity, 83 (5), 1749-1764. doi: 10.1128/IAI.02810-14
Nhu, Nguyen Thi Khanh, Lan, Nguyen Phu Huong, Campbell, James I., Parry, Christopher M., Thompson, Corinne, Tuyen, Ha Thanh, Hoang, Nguyen Van Minh, Tam, Pham Thi Thanh, Le, Vien Minh, Nga, Tran Vu Thieu, Nhu, Tran Do Hoang, Van Minh, Pham, Nga, Nguyen Thi Thu, Thuy, Cao Thu, Dung, Le Thi, Yen, Nguyen Thi Thu, Hao, Nguyen Van, Loan, Huynh Thi, Nghia, Ho Dang Trung, Hien, Tran Tinh, Thwaites, Louise, Thwaites, Guy, Chau, Nguyen Van Vinh and Baker, Stephen (2014). Emergence of carbapenem-resistant Acinetobacter baumanniias the major cause of ventilatorassociated pneumonia in intensive care unit patients at an infectious disease hospital in southern Vietnam. Journal of Medical Microbiology, 63 (Pt 10), 1386-1394. doi: 10.1099/jmm.0.076646-0
Holt, Kathryn E., Tran Vu Thieu Nga, , Duy Pham Thanh, , Ha Vinh, , Kim, Dong Wook, My Phan Vu Tra, , Campbell, James I., Nguyen Van Minh Hoang, , Nguyen Thanh Vinh, , Pham Van Minh, , Cao Thu Thuy, , Tran Thi Thu Nga, , Thompson, Corinne, Tran Thi Ngoc Dung, , Nguyen Thi Khanh Nhu, , Phat Voong Vinh, , Pham Thi Ngoc Tuyet, , Hoang Le Phuc, , Nguyen Thi Nam Lien, , Bui Duc Phu, , Nguyen Thi Thuy Ai, , Nguyen Manh Tien, , Nguyen Dong, , Parry, Christopher M., Tran Tinh Hien, , Farrar, Jeremy J., Parkhill, Julian, Dougan, Gordon, Thomson, Nicholas R. and Baker, Stephen (2013). Tracking the establishment of local endemic populations of an emergent enteric pathogen. Proceedings of the National Academy of Sciences of the United States of America, 110 (43), 17522-17527. doi: 10.1073/pnas.1308632110
Vinh, Ha, Anh, Vo Thi Cuc, Anh, Nguyen Duc, Campbell, James I., Hoang, Nguyen Van Minh, Nga, Tran Vu Thieu, Nhu, Nguyen Thi Khanh, Minh, Pham Van, Thuy, Cao Thu, Duy, Pham Thanh, Phuong, Le Thi, Loan, Ha Thi, Chinh, Mai Thu, Thao, Nguyen Thi Thu, Tham, Nguyen Thi Hong, Mong, Bui Li, Bay, Phan Van Be, Day, Jeremy N., Dolecek, Christiane, Lan, Nguyen Phu Huong, Diep, To Song, Farrar, Jeremy J., Chau, Nguyen Van Vinh, Wolbers, Marcel and Baker, Stephen (2011). A multi-center randomized trial to assess the efficacy of gatifloxacin versus ciprofloxacin for the treatment of shigellosis in Vietnamese children. Plos Neglected Tropical Diseases, 5 (8), e1264. doi: 10.1371/journal.pntd.0001264
Nguyen Thi Khanh Nhu, , Ha Vinh, , Tran Vu Thieu Nga, , Stabler, Richard, Pham Thanh Duy, , Le Thi Minh Vien, , van Doorn, H. Rogier, Cerdeno-Tarraga, Ana, Thomson, Nicholas, Campbell, James, Nguyen Van Minh Hoang, , Tran Thi Thu Nga, , Pham Van Minh, , Cao Thu Thuy, , Wren, Brendan, Farrar, Jeremy and Baker, Stephen (2010). The sudden dominance of blaCTX-M harbouring plasmids in Shigella spp. circulating in Southern Vietnam. PLoS Neglected Tropical Diseases, 4 (6) e702. doi: 10.1371/journal.pntd.0000702
Ha Vinh, , Nguyen Thi Khanh Nhu, , Tran Vu Thieu Nga, , Pham Thanh Duy, , Campbell, James I., Nguyen Van Minh Hoang, , Maciej F Boni, , Phan Vu Tra My, , Parry, Christopher, Tran Thi Thu Nga, , Pham Van Minh, , Cao Thu Thuy, , To Song Diep, , Le Thi Phuong, , Mai Thu Chinh, , Ha Thi Loan, , Nguyen Thi Hong Tham, , Mai Ngoc Lanh, , Bui Li Mong, , Vo Thi Cuc Anh, , Phan Van Be Bay, , Nguyen Van Vinh Chau, , Farrar, Jeremy and Baker, Stephen (2009). A changing picture of shigellosis in southern Vietnam: shifting species dominance, antimicrobial susceptibility and clinical presentation. BMC Infectious Diseases, 9 (1) 204. doi: 10.1186/1471-2334-9-204
Thesis
Nguyen, Thi Khanh Nhu (2018). Molecular and genomic analysis of multidrug resistant Uropathogenic Escherichia coli. PhD Thesis, School of Chemistry and Molecular Biosciences, The University of Queensland. doi: 10.14264/uql.2018.462