Dr James Curson
Institute for Molecular Bioscience
334 62355
Journal Articles
Wang, Yizhuo, Curson, James E.B., Ramnath, Divya, Das Gupta, Kaustav, Reid, Robert C., Karunakaran, Denuja, Fairlie, David P. and Sweet, Matthew J. (2024). Histone deacetylase 7 activates 6-phosphogluconate dehydrogenase via an enzyme-independent mechanism that involves the N-terminal protein-protein interaction domain. Biochemical Journal, 481 (21), 1569-1584. doi: 10.1042/bcj20240380
Das Gupta, Kaustav, Curson, James E. B., Tarique, Abdullah A., Kapetanovic, Ronan, Schembri, Mark A., Fantino, Emmanuelle, Sly, Peter D. and Sweet, Matthew J. (2024). CFTR is required for zinc-mediated antibacterial defense in human macrophages. Proceedings of the National Academy of Sciences, 121 (8) e2315190121, 1-11. doi: 10.1073/pnas.2315190121
Curson, James E. B., Liu, Liping, Luo, Lin, Muusse, Timothy W., Lucas, Richard M., Gunther, Kimberley S., Vajjhala, Parimala R., Abrol, Rishika, Jones, Alun, Kapetanovic, Ronan, Stacey, Katryn J., Stow, Jennifer L. and Sweet, Matthew J. (2023). TLR4 phosphorylation at tyrosine 672 activates the ERK/c‐FOS signaling module for LPS‐induced cytokine responses in macrophages. European Journal of Immunology, 53 (7) e2250056, e2250056. doi: 10.1002/eji.202250056
Das Gupta, Kaustav, Ramnath, Divya, von Pein, Jessica B., Curson, James E. B., Wang, Yizhuo, Abrol, Rishika, Kakkanat, Asha, Moradi, Shayli Varasteh, Gunther, Kimberley S., Murthy, Ambika M. V., Stocks, Claudia J., Kapetanovic, Ronan, Reid, Robert C., Iyer, Abishek, Ilka, Zoe C., Nauseef, William M., Plan, Manuel, Luo, Lin, Stow, Jennifer L., Schroder, Kate, Karunakaran, Denuja, Alexandrov, Kirill, Shakespear, Melanie R., Schembri, Mark A., Fairlie, David P. and Sweet, Matthew J. (2023). HDAC7 is an immunometabolic switch triaging danger signals for engagement of antimicrobial versus inflammatory responses in macrophages. Proceedings of the National Academy of Sciences, 120 (4) e2212813120, 1-12. doi: 10.1073/pnas.2212813120
Liu, Liping, Lucas, Richard M., Nanson, Jeffrey D., Li, Yan, Whitfield, Jason, Curson, James E. B., Tuladhar, Neeraj, Alexandrov, Kirill, Mobli, Mehdi, Sweet, Matthew J., Kobe, Bostjan, Stow, Jennifer and Luo, Lin (2022). The transmembrane adaptor SCIMP recruits tyrosine kinase Syk to phosphorylate Toll-like receptors to mediate selective inflammatory outputs. Journal of Biological Chemistry, 298 (5) 101857, 101857. doi: 10.1016/j.jbc.2022.101857
Curson, James E.B., Luo, Lin, Liu, Liping, Burgess, Belinda J., Bokil, Nilesh J., Wall, Adam A, Brdicka, Tomas, Kapetanovic, Ronan, Stow, Jennifer L and Sweet, Matthew J (2022). An alternative downstream translation start site in the non‐TIR adaptor Scimp enables selective amplification of CpG DNA responses in mouse macrophages. Immunology and Cell Biology, 100 (4), 267-284. doi: 10.1111/imcb.12540
Ramnath, Divya, Das Gupta, Kaustav, Wang, Yizhuo, Abrol, Rishika, Curson, James E. B., Lim, Junxian, Reid, Robert C., Mansell, Ashley, Blumenthal, Antje, Karunakaran, Denuja, Fairlie, David P. and Sweet, Matthew J. (2022). The histone deacetylase Hdac7 supports LPS‐inducible glycolysis and Il‐1β production in murine macrophages via distinct mechanisms. Journal of Leukocyte Biology, 111 (2), 327-336. doi: 10.1002/jlb.2mr1021-260r
Lucas, Richard M., Liu, Liping, Curson, James E. B., Koh, Yvette W. H., Tuladhar, Neeraj, Condon, Nicholas D., Das Gupta, Kaustav, Burgener, Sabrina S., Schroder, Kate, Ingley, Evan, Sweet, Matthew J., Stow, Jennifer L. and Luo, Lin (2021). SCIMP is a spatiotemporal transmembrane scaffold for Erk1/2 to direct pro-inflammatory signaling in TLR-activated macrophages. Cell Reports, 36 (10) 109662, 1-20. doi: 10.1016/j.celrep.2021.109662
Bosch, Marta, Sánchez-Álvarez, Miguel, Fajardo, Alba, Kapetanovic, Ronan, Steiner, Bernhard, Dutra, Filipe, Moreira, Luciana, López, Juan Antonio, Campo, Rocío, Marí, Montserrat, Morales-Paytuví, Frederic, Tort, Olivia, Gubern, Albert, Templin, Rachel M., Curson, James E. B., Martel, Nick, Català, Cristina, Lozano, Francisco, Tebar, Francesc, Enrich, Carlos, Vázquez, Jesús, Del Pozo, Miguel A., Sweet, Matthew J., Bozza, Patricia T., Gross, Steven P., Parton, Robert G. and Pol, Albert (2020). Mammalian lipid droplets are innate immune hubs integrating cell metabolism and host defense. Science, 370 (6514) 8085, 309-+. doi: 10.1126/science.aay8085
Kapetanovic, Ronan, Afroz, Syeda Farhana, Ramnath, Divya, Lawrence, Grace M.E.P., Okada, Takashi, Curson, James E.B., Bruin, Jost, Fairlie, David P., Schroder, Kate, St John, Justin C., Blumenthal, Antje and Sweet, Matthew J. (2020). Lipopolysaccharide promotes Drp1‐dependent mitochondrial fission and associated inflammatory responses in macrophages. Immunology and Cell Biology, 98 (7) imcb.12363, 528-539. doi: 10.1111/imcb.12363
Stocks, Claudia J., Pein, Jessica B., Curson, James E.B., Rae, James, Phan, Minh‐Duy, Foo, Darren, Bokil, Nilesh J., Kambe, Taiho, Peters, Kate M., Parton, Robert G., Schembri, Mark A., Kapetanovic, Ronan and Sweet, Matthew J. (2020). Frontline Science: LPS‐inducible SLC30A1 drives human macrophage‐mediated zinc toxicity against intracellular Escherichia coli. Journal of Leukocyte Biology, 109 (2) JLB.2HI0420-160R, 287-297. doi: 10.1002/jlb.2hi0420-160r
Das Gupta, Kaustav, Shakespear, Melanie R., Curson, James E.B., Murthy, Ambika M.V., Iyer, Abishek, Hodson, Mark P., Ramnath, Divya, Tillu, Vikas A., von Pein, Jessica B., Reid, Robert C., Tunny, Kathryn, Hohenhaus, Daniel M., Moradi, Shayli Varasteh, Kelly, Gregory M., Kobayashi, Takumi, Gunter, Jennifer H., Stevenson, Alexander J., Xu, Weijun, Luo, Lin, Jones, Alun, Johnston, Wayne A., Blumenthal, Antje, Alexandrov, Kirill, Collins, Brett M., Stow, Jennifer L., Fairlie, David P. and Sweet, Matthew J. (2020). Class IIa histone deacetylases drive toll-like receptor-inducible glycolysis and macrophage inflammatory responses via pyruvate kinase M2. Cell Reports, 30 (8), 2712-2728.e8. doi: 10.1016/j.celrep.2020.02.007
Luo, Lin, Curson, James E. B., Liu, Liping, Wall, Adam A., Tuladhar, Neeraj, Lucas, Richard M., Sweet, Matthew J. and Stow, Jennifer L. (2019). SCIMP is a universal Toll‐like receptor adaptor in macrophages. Journal of Leukocyte Biology, 107 (2) JLB.2MA0819-138RR, 251-262. doi: 10.1002/jlb.2ma0819-138rr
Curson, James E. B., Luo, Lin, Sweet, Matthew J. and Stow, Jennifer L. (2018). pTRAPs: Transmembrane adaptors in innate immune signaling. Journal of Leukocyte Biology, 103 (6), 1011-1019. doi: 10.1002/JLB.2RI1117-474R
Thesis
Curson, James E. B. (2021). SCIMP: a novel TLR4 adaptor protein that fine-tunes inflammatory signalling in myeloid cells. PhD Thesis, Institute for Molecular Bioscience, The University of Queensland. doi: 10.14264/93268f4