Professor Denise Doolan
Deputy Director (Research)
Institute for Molecular Bioscience
+61 7 334 62159
Professor Denise Doolan is Director of Research at the Institute for Molecular Bioscience. She joined IMB in 2022 and was previously Deputy Director of the Australian Institute of Tropical Health and Medicine, and Director of the JCU Centre for Molecular Therapeutics, at James Cook University.
She is a molecular immunologist, working on the development of vaccines, diagnostics and host-directed therapeutics for infectious and chronic diseases that impact global public health, with a particular focus on malaria. Her cross-disciplinary research program spans host-pathogen immunity, antigen discovery, vaccine engineering, and biomarker discovery. A particular interest is the application of state-of-the-art genome-based technologies and human models of disease system to identify novel targets for intervention against disease or that predict risk of disease.
She is a recognized world expert in malaria immunology, vaccinology, and omic-based approaches for therapeutic and diagnostic development. She has been honoured as a Fellow of the International Society for Vaccines (2017) and a Fellow of the Australian Society of Parasitology (2019) in recognition of her leadership and contribution to health and medical science in Australia and internationally.
Professor Doolan serves on a number of Executive Boards and Advisory Boards. Most recently, she has been elected as President of the International Society for Vaccines (2021-2023), and has been appointed to the Federal Government’s Australian Medical Research Advisory Board (AMRAB; 2021-2026) to provide specialist insights into Australia’s medical research and innovation priorities.
Researcher biography
Professor Denise Doolan is Director of Research at the Institute for Molecular Bioscience. She joined IMB in 2022 and was previously Deputy Director of the Australian Institute of Tropical Health and Medicine, and Director of the JCU Centre for Molecular Therapeutics, at James Cook University.
She is a molecular immunologist, working on the development of vaccines, diagnostics and host-directed therapeutics for infectious and chronic diseases that impact global public health, with a particular focus on malaria. Her cross-disciplinary research program spans host-pathogen immunity, antigen discovery, vaccine engineering, and biomarker discovery. A particular interest is the application of state-of-the-art genome-based technologies and human models of disease system to identify novel targets for intervention against disease or that predict risk of disease.
She is a recognized world expert in malaria immunology, vaccinology, and omic-based approaches for therapeutic and diagnostic development. She has been honoured as a Fellow of the International Society for Vaccines (2017) and a Fellow of the Australian Society of Parasitology (2019) in recognition of her leadership and contribution to health and medical science in Australia and internationally.
Professor Doolan serves on a number of Executive Boards and Advisory Boards. Most recently, she has been elected as President of the International Society for Vaccines (2021-2023), and has been appointed to the Federal Government's Australian Medical Research Advisory Board (AMRAB; 2021-2026) to provide specialist insights into Australia's medical research and innovation priorities.
Book Chapters
Driguez, Patrick, Doolan, Denise L., Molina, Douglas M., Loukas, Alex, Trieu, Angela, Felgner, Phil L. and McManus, Donald P. (2015). Protein microarrays for parasite antigen discovery. Parasite genomics protocols . (pp. 221-33) edited by Christopher Peacock. Cham, Switzerland: Springer. doi: 10.1007/978-1-4939-1438-8_13
Loukas, Alex, Gaze, Soraya, Pearson, Mark, Doolan, Denise, Felgner, Philip, Diemert, David, Mcmanus, Donald P., Driguez, Patrick and Bethony, Jeffrey (2012). Schistosomiasis Vaccines - New Approaches to Antigen Discovery and Promising New Candidates. Parasitic Helminths: Targets, Screens, Drugs and Vaccines. (pp. 421-433) Wiley-VCH. doi: 10.1002/9783527652969.ch25
Hedstrom, Richard C. and Doolan, Denise L. (2002). DNA vaccination. Malaria methods and protocols. (pp. 347-59) edited by Denise L. Doolan. New York, NY, United States: Humana Press. doi: 10.1385/1-59259-271-6:347
Doolan, Denise L. (2002). Assessing antigen-specific CD8+ CTL responses in humans. Malaria Methods and Protocols. (pp. 445-456) edited by Denise L. Doolan. New York, NY, United States: Humana Press. doi: 10.1385/1-59259-271-6:445
Journal Articles
Browne, Daniel J., Kelly, Ashton M., Brady, Jamie, Proietti, Carla, Sarathkumara, Yomani D., Pattinson, David J. and Doolan, Denise L. (2023). Evaluating the stability of host-reference gene expression and simultaneously quantifying parasite burden and host immune responses in murine malaria. Scientific Reports, 13 (1) 21071, 1-11. doi: 10.1038/s41598-023-48066-9
Thanigaimani, Shivshankar, Iyer, Vikram, Bingley, John, Browne, Daniel, Phie, James, Doolan, Denise and Golledge, Jonathan (2023). Association of serum microRNAs with abdominal aortic aneurysm diagnosis and growth. European Journal of Vascular and Endovascular Surgery, 65 (4), 573-581. doi: 10.1016/j.ejvs.2022.12.028
Argirion, Ilona, Pfeiffer, Ruth M., Proietti, Carla, Coghill, Anna E., Yu, Kelly J., Middeldorp, Jaap M., Sarathkumara, Yomani D., Hsu, Wan-Lun, Chien, Yin-Chu, Lou, Pei-Jen, Wang, Cheng-Ping, Rothman, Nathaniel, Lan, Qing, Chen, Chien-Jen, Mbulaiteye, Sam M., Jarrett, Ruth F., Glimelius, Ingrid, Smedby, Karin E., Hjalgrim, Henrik, Hildesheim, Allan, Doolan, Denise L. and Liu, Zhiwei (2023). Comparative analysis of the humoral immune response to the EBV proteome across EBV-related malignancies. Cancer Epidemiology, Biomarkers and Prevention, 32 (5), OF1-OF10. doi: 10.1158/1055-9965.epi-22-0452
Lam, W K Jacky, King, Ann D, Miller, Jacob A, Liu, Zhiwei, Yu, Kelly J, Chua, Melvin L K, Ma, Brigette B Y, Chen, Ming Yuan, Pinsky, Benjamin A, Lou, Pei-Jen, Woo, John K S, Hsu, Wan-Lun, Simon, Julia, Doolan, Denise L, Waterboer, Tim, Hui, Edwin P, Li, Hui, Tsang, Raymond K, Wong, Kenneth C W, Goh, Julian P, Vlantis, Alexander C, Ai, Qi Yong, Wong, Lun M, Abdullah, Victor, Lin, Jin Ching, Chen, Chien-Jen, Pfeiffer, Ruth M, Le, Quynh-Thu, Lee, Anne W M ... Hildesheim, Allan (2023). Recommendations for Epstein-Barr virus-based screening for nasopharyngeal cancer in high- and intermediate-risk regions. JNCI: Journal of the National Cancer Institute, 115 (4), 355-364. doi: 10.1093/jnci/djad012
Ratnatunga, Champa N., Tungatt, Katie, Proietti, Carla, Halstrom, Sam, Holt, Michael R., Lutzky, Viviana P., Price, Patricia, Doolan, Denise L., Bell, Scott C., Field, Matt A., Kupz, Andreas, Thomson, Rachel M. and Miles, John J. (2022). Characterizing and correcting immune dysfunction in non-tuberculous mycobacterial disease. Frontiers in Immunology, 13 1047781, 1-20. doi: 10.3389/fimmu.2022.1047781
Ryan, Stephanie M., Ruscher, Roland, Johnston, Wayne A., Pickering, Darren A., Kennedy, Malcolm W., Smith, Brian O., Jones, Linda, Buitrago, Geraldine, Field, Matt A., Esterman, Adrian J., McHugh, Connor P., Browne, Daniel J., Cooper, Martha M., Ryan, Rachael Y M, Doolan, Denise L., Engwerda, Christian R., Miles, Kim, Mitreva, Makedonka, Croese, John, Rahman, Tony, Alexandrov, Kirill, Giacomin, Paul R. and Loukas, Alex (2022). Novel antiinflammatory biologics shaped by parasite-host coevolution. Proceedings of the National Academy of Sciences of the United States of America, 119 (36) 2202795119, 1-9. doi: 10.1073/pnas.2202795119
Sarathkumara, Yomani D., Browne, Daniel J., Kelly, Ashton M., Pattinson, David J., Rush, Catherine M., Warner, Jeffrey, Proietti, Carla and Doolan, Denise L. (2022). The effect of tropical temperatures on the quality of RNA extracted from stabilized whole-blood samples. International Journal of Molecular Sciences, 23 (18) 10609, 1-15. doi: 10.3390/ijms231810609
Browne, Daniel J., Kelly, Ashton M., Brady, Jamie L. and Doolan, Denise L. (2022). A high-throughput screening RT-qPCR assay for quantifying surrogate markers of immunity from PBMCs. Frontiers in Immunology, 13 962220, 1-12. doi: 10.3389/fimmu.2022.962220
Karunathilaka, Amali, Halstrom, Samuel, Price, Patricia, Holt, Michael, Lutzky, Viviana P., Doolan, Denise L., Kupz, Andreas, Bell, Scott C., Thomson, Rachel M., Miles, John J. and Ratnatunga, Champa N. (2022). CD161 expression defines new human γδ T cell subsets. Immunity and Ageing, 19 (1) 11, 1-8. doi: 10.1186/s12979-022-00269-w
Coghill, Anna E., Fang, Jianwen, Liu, Zhiwei, Chen, Chien-Jen, Jarrett, Ruth F., Hjalgrim, Henrik, Proietti, Carla, Yu, Kelly J., Hsu, Wan-Lun, Lou, Pei-Jen, Wang, Chen-Ping, Zhao, Yingdong, Doolan, Denise L. and Hildesheim, Allan (2022). Identifying Epstein-Barr virus peptide sequences associated with differential IgG antibody response. International Journal of Infectious Diseases, 114, 65-71. doi: 10.1016/j.ijid.2021.10.054
Doolan, Denise, Lu, Shan, Ross, Ted and Cox, Manon (2022). Meet the fellows: Everything about ISV. Human Vaccines and Immunotherapeutics, 18 (4) 2096964. doi: 10.1080/21645515.2022.2096964
De Sousa, Karina P., Potriquet, Jeremy, Mulvenna, Jason, Sotillo, Javier, Groves, Penny L., Loukas, Alex, Apte, Simon H. and Doolan, Denise L. (2022). Proteomic identification of the contents of small extracellular vesicles from in vivo Plasmodium yoelii infection. International Journal for Parasitology, 52 (1), 35-45. doi: 10.1016/j.ijpara.2021.06.001
Doolan, Denise L. (2021). Malaria research in Australia: looking through the lens of the past towards the future. International Journal for Parasitology, 51 (13-14), 1255-1263. doi: 10.1016/j.ijpara.2021.11.005
Liu, Zhiwei, Sarathkumara, Yomani D., Chan, John K. C., Kwong, Yok-Lam, Lam, Tai Hing, Ip, Dennis Kai Ming, Chiu, Brian C. -H., Xu, Jun, Su, Yu-Chieh, Proietti, Carla, Cooper, Martha M., Yu, Kelly J., Bassig, Bryan, Liang, Raymond, Hu, Wei, Ji, Bu-Tian, Coghill, Anna E., Pfeiffer, Ruth M., Hildesheim, Allan, Rothman, Nathaniel, Doolan, Denise L. and Lan, Qing (2021). Characterization of the humoral immune response to the EBV proteome in extranodal NK/T-cell lymphoma. Scientific Reports, 11 (1) 23664, 1-8. doi: 10.1038/s41598-021-02788-w
Fulford, Thomas S., Van, Huy, Gherardin, Nicholas A., Zheng, Shuning, Ciula, Marcin, Drummer, Heidi E., Redmond, Samuel, Tan, Hyon-Xhi, Boo, Irene, Center, Rob J., Li, Fan, Grimley, Samantha L., Wines, Bruce D., Nguyen, Thi H. O., Mordant, Francesca L., Ellenberg, Paula, Rowntree, Louise C., Kedzierski, Lukasz, Cheng, Allen C., Doolan, Denise L., Matthews, Gail, Bond, Katherine, Hogarth, P. Mark, McQuilten, Zoe, Subbarao, Kanta, Kedzierska, Katherine, Juno, Jennifer A., Wheatley, Adam K., Kent, Stephen J. ... Godfrey, Dale (2021). A point-of-care lateral flow assay for neutralising antibodies against SARS-CoV-2. EBioMedicine, 74 103729, 1-16. doi: 10.1016/j.ebiom.2021.103729
Selva, Kevin J., van de Sandt, Carolien E., Lemke, Melissa M., Lee, Christina Y., Shoffner, Suzanne K., Chua, Brendon Y., Davis, Samantha K., Nguyen, Thi H. O., Rowntree, Louise C., Hensen, Luca, Koutsakos, Marios, Wong, Chinn Yi, Mordant, Francesca, Jackson, David C., Flanagan, Katie L., Crowe, Jane, Tosif, Shidan, Neeland, Melanie R., Sutton, Philip, Licciardi, Paul V., Crawford, Nigel W., Cheng, Allen C., Doolan, Denise L., Amanat, Fatima, Krammer, Florian, Chappell, Keith, Modhiran, Naphak, Watterson, Daniel, Young, Paul ... Chung, Amy W. (2021). Systems serology detects functionally distinct coronavirus antibody features in children and elderly. Nature Communications, 12 (1) 2037, 2037. doi: 10.1038/s41467-021-22236-7
Doolan, Denise L., Kozlakidis, Zisis, Zhang, Zhongheng, Paessler, Slobodan, Su, Longxiang, Yokota, Yasuko Tsunetsugu, Shioda, Tatsuo, Rodriguez-Palacios, Alexander, Kaynar, Ata Murat, Ahmed, Rukhsana, Samy, Abdallah, Bradby, Hannah, Kalergis, Alexis M., Dutta, Mohan Jyoti, Kogut, Michael and Zhang, Shen-Ying (2021). Coronavirus Disease (COVID-19): Pathophysiology, epidemiology, clinical management and public health response. Frontiers in Public Health, 9 807159, 1-2. doi: 10.3389/fpubh.2021.807159
Pearson, Mark S., Tedla, Bemnet A., Mekonnen, Gebeyaw G., Proietti, Carla, Becker, Luke, Nakajima, Rie, Jasinskas, Al, Doolan, Denise L., Amoah, Abena S., Knopp, Stefanie, Rollinson, David, Ali, Said M., Kabole, Fatma, Hokke, Cornelis H., Adegnika, Akim A., Field, Matt A., van Dam, Govert, Corstjens, Paul L. A. M., Mduluza, Takafira, Mutapi, Francisca, Oeuvray, Claude, Greco, Beatrice, Chaiyadet, Sujittra, Laha, Thewarach, Cai, Pengfei, McManus, Donald P., Bottazzi, Maria Elena, Felgner, Philip L., Sotillo, Javier and Loukas, Alex (2021). Immunomics-guided discovery of serum and urine antibodies for diagnosing urogenital schistosomiasis: a biomarker identification study. The Lancet Microbe, 2 (11), E617-E626. doi: 10.1016/s2666-5247(21)00150-6
Wong, Yide, Meehan, Michael T., Burrows, Scott R., Doolan, Denise L. and Miles, John J. (2021). Estimating the global burden of Epstein–Barr virus-related cancers. Journal of Cancer Research and Clinical Oncology, 148 (1), 31-46. doi: 10.1007/s00432-021-03824-y
Poole, Jessica, Hartley-Tassell, Lauren E., Day, Christopher J., Stanisic, Danielle, Groves, Penny L., Chakravarty, Sumana, Sim, B. Kim Lee, Hoffman, Stephen L., Tiralongo, Joe, Bovin, Nicolai, Doolan, Denise L. and Jennings, Michael P. (2021). Identification of the Glycan binding profile of human and rodent Plasmodium sporozoites. ACS Infectious Diseases, 7 (8), 2383-2389. doi: 10.1021/acsinfecdis.1c00084
Nguyen, Thi H. O., Rowntree, Louise C., Petersen, Jan, Chua, Brendon Y., Hensen, Luca, Kedzierski, Lukasz, van de Sandt, Carolien E., Chaurasia, Priyanka, Tan, Hyon-Xhi, Habel, Jennifer R., Zhang, Wuji, Allen, Lilith F., Earnest, Linda, Mak, Kai Yan, Juno, Jennifer A., Wragg, Kathleen, Mordant, Francesca L., Amanat, Fatima, Krammer, Florian, Mifsud, Nicole A., Doolan, Denise L., Flanagan, Katie L., Sonda, Sabrina, Kaur, Jasveen, Wakim, Linda M., Westall, Glen P., James, Fiona, Mouhtouris, Effie, Gordon, Claire L. ... Kedzierska, Katherine (2021). CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope display high naive precursor frequency and TCR promiscuity. Immunity, 54 (5), 1066-1082+. doi: 10.1016/j.immuni.2021.04.009
Koutsakos, Marios, Rowntree, Louise C., Hensen, Luca, Chua, Brendon Y., van de Sandt, Carolien E., Habel, Jennifer R., Zhang, Wuji, Jia, Xiaoxiao, Kedzierski, Lukasz, Ashhurst, Thomas M., Putri, Givanna H., Marsh-Wakefield, Felix, Read, Mark N., Edwards, Davis N., Clemens, E. Bridie, Wong, Chinn Yi, Mordant, Francesca L., Juno, Jennifer A., Amanat, Fatima, Audsley, Jennifer, Holmes, Natasha E., Gordon, Claire L., Smibert, Olivia C., Trubiano, Jason A., Hughes, Carly M., Catton, Mike, Denholm, Justin T., Tong, Steven Y. C., Doolan, Denise L. ... Kedzierska, Katherine (2021). Integrated immune dynamics define correlates of COVID-19 severity and antibody responses. Cell Reports Medicine, 2 (3) 100208, 1-21. doi: 10.1016/j.xcrm.2021.100208
Rowntree, Louise C., Chua, Brendon Y., Nicholson, Suellen, Koutsakos, Marios, Hensen, Luca, Douros, Celia, Selva, Kevin, Mordant, Francesca L., Wong, Chinn Yi, Habel, Jennifer R., Zhang, Wuji, Jia, Xiaoxiao, Allen, Lily, Doolan, Denise L., Jackson, David C., Wheatley, Adam K., Kent, Stephen J., Amanat, Fatima, Krammer, Florian, Subbarao, Kanta, Cheng, Allen C., Chung, Amy W., Catton, Mike, Nguyen, Thi H. O., van de Sandt, Carolien E. and Kedzierska, Katherine (2021). Robust correlations across six SARS-CoV-2 serology assays detecting distinct antibody features. Clinical and Translational Immunology, 10 (3) e1258, 1-18. doi: 10.1002/cti2.1258
Hicks, Sarah M., Pohl, Kai, Neeman, Teresa, McNamara, Hayley A., Parsons, Kate M., He, Jin-shu, Ali, Sidra A., Nazir, Samina, Rowntree, Louise C., Nguyen, Thi H. O., Kedzierska, Katherine, Doolan, Denise L., Vinuesa, Carola G., Cook, Matthew C., Coatsworth, Nicholas, Myles, Paul S., Kurth, Florian, Sander, Leif E., Mann, Graham J., Gruen, Russell L., George, Amee J., Gardiner, Elizabeth E. and Cockburn, Ian A. (2021). A dual-antigen enzyme-linked immunosorbent assay allows the assessment of severe acute respiratory syndrome coronavirus 2 antibody seroprevalence in a low-transmission setting. Journal of Infectious Diseases, 223 (1), 10-14. doi: 10.1093/infdis/jiaa623
Loiseau, Claire, Traore, Boubacar, Ongoiba, Aissata, Kayentao, Kassoum, Doumbo, Safiatou, Doumtabe, Didier, de Sousa, Karina P., Brady, Jamie L., Proietti, Carla, Crompton, Peter D. and Doolan, Denise L. (2021). Memory CD8+ T cell compartment associated with delayed onset of Plasmodium falciparum infection and better parasite control in sickle-cell trait children. Clinical and Translational Immunology, 10 (3) e1265, 1-12. doi: 10.1002/cti2.1265
Habel, Jennifer R., Nguyen, Thi H. O., van de Sandt, Carolien E., Juno, Jennifer A., Chaurasia, Priyanka, Wragg, Kathleen, Koutsakos, Marios, Hensen, Luca, Jia, Xiaoxiao, Chua, Brendon, Zhang, Wuji, Tan, Hyon-Xhi, Flanagan, Katie L., Doolan, Denise L., Torresi, Joseph, Chen, Weisan, Wakim, Linda M., Cheng, Allen C., Doherty, Peter C., Petersen, Jan, Rossjohn, Jamie, Wheatley, Adam K., Kent, Stephen J., Rowntree, Louise C. and Kedzierska, Katherine (2020). Suboptimal SARS-CoV-2-specific CD8+ T cell response associated with the prominent HLA-A*02:01 phenotype. Proceedings of the National Academy of Sciences of the United States of America, 117 (39), 24384-24391. doi: 10.1073/pnas.2015486117
Pattinson, David J., Apte, Simon H., Wibowo, Nani, Rivera-Hernandez, Tania, Groves, Penny L., Middelberg, Anton P. J. and Doolan, Denise L. (2020). Chimeric Virus-Like Particles and Capsomeres Induce Similar CD8+ T Cell Responses but Differ in Capacity to Induce CD4+ T Cell Responses and Antibody Responses. Frontiers in Immunology, 11 564627, 1-13. doi: 10.3389/fimmu.2020.564627
Kifle, Desalegn Woldeyohannes, Chaiyadet, Sujittra, Waardenberg, Ashley J., Wise, Ingrid, Cooper, Martha, Becker, Luke, Doolan, Denise L., Laha, Thewarach, Sotillo, Javier, Pearson, Mark S. and Loukas, Alex (2020). Uptake of Schistosoma mansoni extracellular vesicles by human endothelial and monocytic cell lines and impact on vascular endothelial cell gene expression. International Journal for Parasitology, 50 (9), 685-696. doi: 10.1016/j.ijpara.2020.05.005
Liu, Zhiwei, Jarrett, Ruth F, Hjalgrim, Henrik, Proietti, Carla, Chang, Ellen T., Smedby, Karin E., Yu, Kelly J., Lake, Annette, Troy, Sally, McAulay, Karen A., Pfeiffer, Ruth M., Adami, Hans-Olov, Glimelius, Bengt, Melbye, Mads, Hildesheim, Allan, Doolan, Denise L. and Coghill, Anna E. (2020). Evaluation of the antibody response to the EBV proteome in EBV-associated classical Hodgkin lymphoma. International Journal of Cancer, 147 (3), 608-618. doi: 10.1002/ijc.32741
Coghill, Anna E., Pfeiffer, Ruth M., Proietti, Carla, Hsu, Wan-Lun, Chien, Yin-Chu, Lekieffre, Lea, Krause, Lutz, Teng, Andy, Pablo, Jocelyn, Yu, Kelly J., Lou, Pei-Jen, Wang, Cheng-Ping, Liu, Zhiwei, Chen, Chien-Jen, Middeldorp, Jaap, Mulvenna, Jason, Bethony, Jeff, Hildesheim, Allan and Doolan, Denise L. (2020). Erratum: Correction: Identification of a Novel, EBV-based Antibody Risk Stratification Signature for Early Detection of Nasopharyngeal Carcinoma in Taiwan (Clinical cancer research : an official journal of the American Association for Cancer Research (2018) 24 6 (1305-1314)). Clinical Cancer Research, 26 (13), 3496-3496. doi: 10.1158/1078-0432.CCR-20-1828
Simon, Julia, Liu, Zhiwei, Brenner, Nicole, Yu, Kelly J., Hsu, Wan-Lun, Wang, Cheng-Ping, Chien, Yin-Chu, Coghill, Anna E., Chen, Chien-Jen, Butt, Julia, Proietti, Carla, Doolan, Denise L., Hildesheim, Allan and Waterboer, Tim (2020). Validation of an Epstein-Barr virus antibody risk stratification signature for nasopharyngeal carcinoma by use of multiplex serology. Journal of Clinical Microbiology, 58 (5) e00077-20, 1-9. doi: 10.1128/JCM.00077-20
Longley, Rhea J., White, Michael T., Takashima, Eizo, Brewster, Jessica, Morita, Masayuki, Harbers, Matthias, Obadia, Thomas, Robinson, Leanne J., Matsuura, Fumie, Liu, Zoe S. J., Li-Wai-Suen, Connie S. N., Tham, Wai-Hong, Healer, Julie, Huon, Christele, Chitnis, Chetan E., Nguitragool, Wang, Monteiro, Wuelton, Proietti, Carla, Doolan, Denise L., Siqueira, Andre M., Ding, Xavier C., Gonzalez, Iveth J., Kazura, James, Lacerda, Marcus, Sattabongkot, Jetsumon, Tsuboi, Takafumi and Mueller, Ivo (2020). Development and validation of serological markers for detecting recent Plasmodium vivax infection. Nature Medicine, 26 (5), 741-749+. doi: 10.1038/s41591-020-0841-4
Loiseau, Claire, Doumbo, Ogobara K., Traore, Boubacar, Brady, Jamie L., Proietti, Carla, Sousa, Karina P., Crompton, Peter D. and Doolan, Denise L. (2020). A novel population of memory‐activated natural killer cells associated with low parasitaemia in Plasmodium falciparum ‐exposed sickle‐cell trait children. Clinical and Translational Immunology, 9 (4) e1125, e1125. doi: 10.1002/cti2.1125
Browne, Daniel J., Brady, Jamie L., Waardenberg, Ashley J., Loiseau, Claire and Doolan, Denise L. (2020). An analytically and diagnostically sensitive RNA extraction and RT-qPCR protocol for peripheral blood mononuclear cells. Frontiers in Immunology, 11 402, 1-15. doi: 10.3389/fimmu.2020.00402
Loiseau, Claire, Cooper, Martha M. and Doolan, Denise L. (2020). Deciphering host immunity to malaria using systems immunology. Immunological Reviews, 293 (1), 115-143. doi: 10.1111/imr.12814
Proietti, Carla, Krause, Lutz, Trieu, Angela, Dodoo, Daniel, Gyan, Ben, Koram, Kwadwo A., Rogers, William O., Richie, Thomas L., Crompton, Peter D., Felgner, Philip L. and Doolan, Denise L. (2020). Immune signature against Plasmodium falciparum antigens predicts clinical immunity in distinct malaria endemic communities. Molecular and Cellular Proteomics, 19 (1), 101-113. doi: 10.1074/mcp.RA118.001256
Apte, Simon H, Minigo, Gabriela, Groves, Penny L, Spargo, Jessie C, Plebanski, Magdalena, Grigg, Matthew J, Kenangalem, Enny, Burel, Julie G, Loughland, Jessica R, Flanagan, Katie L, Piera, Kim A, William, Timothy, Price, Ric N, Woodberry, Tonia, Barber, Bridget E, Anstey, Nicholas M and Doolan, Denise L (2020). A population of CD4hi CD38hi T cells correlates with disease severity in patients with acute malaria. Clinical and Translational Immunology, 9 (11) e1209, 1-18. doi: 10.1002/cti2.1209
Coghill, Anna E., Proietti, Carla, Liu, Zhiwei, Krause, Lutz, Bethony, Jeff, Prokunina-Olsson, Ludmila, Obajemu, Adeola, Nkrumah, Francis, Biggar, Robert J., Bhatia, Kishor, Hildesheim, Allan, Doolan, Denise L. and Mbulaiteye, Sam M. (2020). The association between the comprehensive Epstein–Barr virus serologic profile and endemic Burkitt lymphoma. Cancer Epidemiology Biomarkers and Prevention, 29 (1), 57-62. doi: 10.1158/1055-9965.EPI-19-0551
Ratnatunga, Champa N., Lutzky, Viviana P., Kupz, Andreas, Doolan, Denise L., Reid, David W., Field, Matthew, Bell, Scott C., Thomson, Rachel M. and Miles, John J. (2020). The rise of non-tuberculosis mycobacterial lung disease. Frontiers in Immunology, 11 303, 303. doi: 10.3389/fimmu.2020.00303
Tessema, Sofonias K., Nakajima, Rie, Jasinskas, Algis, Monk, Stephanie L., Lekieffre, Lea, Lin, Enmoore, Kiniboro, Benson, Proietti, Carla, Siba, Peter, Felgner, Philip L., Doolan, Denise L., Mueller, Ivo and Barry, Alyssa E. (2019). Protective immunity against severe malaria in children is associated with a limited repertoire of antibodies to conserved PfEMP1 variants. Cell Host & Microbe, 26 (5), 579-590+. doi: 10.1016/j.chom.2019.10.012
Liu, Zhiwei, Yu, Kelly J., Coghill, Anna E., Brenner, Nicole, Cao, Su-Mei, Chen, Chien-Jen, Chen, Yufeng, Doolan, Denise L., Hsu, Wan-Lun, Labo, Nazzarena, Middeldorp, Jaap M., Miley, Wendell, Simon, Julia, Wang, Cheng-Ping, Waterboer, Tim, Whitby, Denise, Xie, Shang-Hang, Ye, Weimin and Hildesheim, Allan (2019). Multilaboratory assessment of Epstein-Barr virus serologic assays: the case for standardization. Journal of Clinical Microbiology, 57 (11) e01107-19, 1-8. doi: 10.1128/JCM.01107-19
Cooper, Martha M., Loiseau, Claire and Doolan, Denise L. (2019). Casting a wide net around immunity to malaria catches p53. Immunity, 51 (4), 603-605. doi: 10.1016/j.immuni.2019.09.011
Boyle, M. J., Chan, J. A., Handayuni, I., Reiling, L., Feng, G., Hilton, A., Kurtovic, L., Oyong, D., Piera, K. A., Barber, B. E., William, T., Eisen, D. P., Minigo, G., Langer, C., Drew, D. R., de Labastida Rivera, F., Amante, F. H., Williams, T. N., Kinyanjui, S., Marsh, K., Doolan, D. L., Engwerda, C., Fowkes, F. J.I., Grigg, M. J., Mueller, I., McCarthy, J. S., Anstey, N. M. and Beeson, J. G. (2019). IgM in human immunity to Plasmodium falciparum malaria. Science Advances, 5 (9) eaax4489, eaax4489. doi: 10.1126/sciadv.aax4489
Doolan, Denise L. and Ross, Ted M. (2019). 2018 ISV Congress: advances in the 100 years since the world’s deadliest pandemic. Human Vaccines & Immunotherapeutics, 15 (9), 2006-2008. doi: 10.1080/21645515.2019.1660544
Dobaño, Carlota, Nhabomba, Augusto J, Manaca, Maria N, Berthoud, Tamara, Aguilar, Ruth, Quintó, Llorenç, Barbosa, Arnoldo, Rodríguez, Mauricio H, Jiménez, Alfons, Groves, Penny L, Santano, Rebeca, Bassat, Quique, Aponte, John J, Guinovart, Caterina, Doolan, Denise L and Alonso, Pedro L (2019). A balanced proinflammatory and regulatory cytokine signature in young African children is associated with lower risk of clinical malaria. Clinical Infectious Diseases, 69 (5) ciy934, 820-828. doi: 10.1093/cid/ciy934
Pattinson, David J., Apte, Simon H., Wibowo, Nani, Chuan, Yap P., Rivera-Hernandez, Tania, Groves, Penny L., Lua, Linda H., Middelberg, Anton P. J. and Doolan, Denise L. (2019). Chimeric Murine Polyomavirus Virus-Like Particles Induce Plasmodium Antigen-Specific CD8(+) T Cell and Antibody Responses. Frontiers in Cellular and Infection Microbiology, 9 (JUN) 215, 215. doi: 10.3389/fcimb.2019.00215
Cooper, Martha M., Loiseau, Claire, McCarthy, James S. and Doolan, Denise L. (2019). Human challenge models: tools to accelerate the development of malaria vaccines. Expert Review of Vaccines, 18 (3), 241-251. doi: 10.1080/14760584.2019.1580577
Schreeg, Megan E, Marr, Henry S, Tarigo, Jaime L, Sherrill, Meredith K, Outi, Hilton K, Scholl, Elizabeth H, Bird, David M, Vigil, Adam, Hung, Chris, Nakajima, Rie, Liang, Li, Trieu, Angela, Doolan, Denise L, Thomas, Jennifer E, Levy, Michael G, Reichard, Mason V, Felgner, Philip L, Cohn, Leah A and Birkenheuer, Adam J (2018). Identification of Cytauxzoon felis antigens via protein microarray and assessment of expression library immunization against cytauxzoonosis. Clinical Proteomics, 15 (1) 44, 1-17. doi: 10.1186/s12014-018-9218-9
Wangchuk, Phurpa, Apte, Simon H., Smout, Michael J., Groves, Penny L., Loukas, Alex and Doolan, Denise L. (2018). Defined Small Molecules Produced by Himalayan Medicinal Plants Display Immunomodulatory Properties. International journal of molecular sciences, 19 (11) 3490, 3490. doi: 10.3390/ijms19113490
Doolan, Denise L. and Lu, Shan (2018). ISV Congress back to Europe. Human Vaccines and Immunotherapeutics, 14 (9), 2101-2104. doi: 10.1080/21645515.2018.1518065
Liu, Zhiwei, Coghill, Anna E., Pfeiffer, Ruth M., Proietti, Carla, Hsu, Wan-Lun, Chien, Yin-Chu, Lekieffre, Lea, Krause, Lutz, Yu, Kelly J., Lou, Pei-Jen, Wang, Cheng-Ping, Mulvenna, Jason, Middeldorp, Jaap M., Bethony, Jeff, Chen, Chien-Jen, Doolan, Denise L. and Hildesheim, Allan (2018). Patterns of interindividual variability in the antibody repertoire targeting proteins across the Epstein-Barr virus proteome. The Journal of Infectious Diseases, 217 (12), 1923-1931. doi: 10.1093/infdis/jiy122
Lutzky, Viviana P., Ratnatunga, Champa N., Smith, Daniel J., Kupz, Andreas, Doolan, Denise L., Reid, David W., Thomson, Rachel M., Bell, Scott C. and Miles, John J. (2018). Anomalies in T cell function are associated with individuals at risk of Mycobacterium abscessus complex infection. Frontiers in Immunology, 9 (June) 1319, 1319. doi: 10.3389/fimmu.2018.01319
Dobaño, Carlota, Berthoud, Tamara, Manaca, Maria Nelia, Nhabomba, Augusto, Guinovart, Caterina, Aguilar, Ruth, Barbosa, Arnoldo, Groves, Penny, Rodríguez, Mauricio H, Jimenez, Alfons, Quimice, Lazaro M, Aponte, John J, Ordi, Jaume, Doolan, Denise L, Mayor, Alfredo and Alonso, Pedro L (2018). High production of pro-inflammatory cytokines by maternal blood mononuclear cells is associated with reduced maternal malaria but increased cord blood infection. Malaria Journal, 17 (1) 177, 1-13. doi: 10.1186/s12936-018-2317-2
Eskandari, Sharareh, Pattinson, David, Stephenson, Rachel J., Groves, Penny L., Apte, Simon H., Sedaghat, Bita, Chandurudu, Saranya, Doolan, Denise L. and Toth, Istvan (2018). The influence of physicochemical properties of lipopeptide adjuvants on immune response: a rationale for engineering a potent vaccine. Chemistry: A European Journal, 24 (39), 9892-9902. doi: 10.1002/chem.201801378
Coghill, Anna E., Pfeiffer, Ruth M., Proietti, Carla, Hsu, Wan-Lun, Chien, Yin-Chu, Lekieffre, Lea, Krause, Lutz, Teng, Andy, Pablo, Jocelyn, Yu, Kelly J., Lou, Pei-Jen, Wang, Cheng-Ping, Liu, Zhiwei, Chen, Chien-Jen, Middeldorp, Jaap, Mulvenna, Jason, Bethony, Jeff, Hildesheim, Allan and Doolan, Denise L. (2018). Identification of a Novel, EBV-based antibody risk stratification signature for early detection of nasopharyngeal carcinoma in Taiwan. Clinical Cancer Research, 24 (6), 1305-1314. doi: 10.1158/1078-0432.CCR-17-1929
Bruder, Joseph T., Chen, Ping, Ekberg, Greg, Smith, Emily C., Lazarski, Christopher A., Myers, Bennett A., Bolton, Jessica, Sedegah, Martha, Villasante, Eileen, Richie, Thomas L., King, C Richter, Aguiar, Joao C., Doolan, Denise L. and Brough, Douglas E. (2017). Profiling the targets of protective CD8+ T cell responses to infection. Molecular Therapy - Methods & Clinical Development, 7, 20-31. doi: 10.1016/j.omtm.2017.08.003
Schussek, Sophie, Trieu, Angela, Apte, Simon H., Sidney, John, Sette, Alessandro and Doolan, Denise L. (2017). Novel Plasmodium antigens identified via genome-based antibody screen induce protection associated with polyfunctional T cell responses. Scientific reports, 7 (1) 15053, 1-18. doi: 10.1038/s41598-017-15354-0
Bryan, Donna, Silva, Nilupa, Rigsby, Peter, Dougall, Thomas, Corran, Patrick, Bowyer, Paul W, Ho, Mei Mei, Collaborative study group and Doolan, Denise L. (2017). The establishment of a WHO Reference Reagent for anti-malaria (Plasmodium falciparum) human serum. Malaria Journal, 16 (1) 314, 10-10. doi: 10.1186/s12936-017-1958-x
Burel, Julie G., Apte, Simon H., Groves, Penny L., Boyle, Michelle J., Langer, Christine, Beeson, James G., McCarthy, James S. and Doolan, Denise L. (2017). Dichotomous miR expression and immune responses following primary blood-stage malaria. JCI Insight, 2 (15) e93434. doi: 10.1172/jci.insight.93434
Loughland, Jessica R., Minigo, Gabriela, Sarovich, Derek S., Field, Matt, Tipping, Peta E., Montes de Oca, Marcela, Piera, Kim A., Amante, Fiona H., Barber, Bridget E., Grigg, Matthew J., William, Timothy, Good, Michael F., Doolan, Denise L., Engwerda, Christian R., Anstey, Nicholas M., McCarthy, James S. and Woodberry, Tonia (2017). Plasmacytoid dendritic cells appear inactive during sub-microscopic Plasmodium falciparum blood-stage infection, yet retain their ability to respond to TLR stimulation. Scientific Reports, 7 (1) 2596. doi: 10.1038/s41598-017-02096-2
Obaldia, Nicanor, Stockelman, Michael G., Otero, William, Cockrill, Jennifer A., Ganeshan, Harini, Abot, Esteban N., Zhang, Jianfeng, Limbach, Keith, Charoenvit, Yupin, Doolan, Denise L., Tang, De-Chu C and Richie, Thomas L (2017). A Plasmodium vivax plasmid DNA- and adenovirus-vectored malaria vaccine encoding blood-stage antigens AMA1 and MSP142 in a prime/boost heterologous immunization regimen partially protects Aotus monkeys against blood-stage challenge. Clinical and Vaccine Immunology, 24 (4) e00539, 1-16. doi: 10.1128/CVI.00539-16
Burel, Julie G., Apte, Simon H., Groves, Penny L., McCarthy, James S. and Doolan, Denise L. (2017). Polyfunctional and IFN- monofunctional human CD4 T cell populations are molecularly distinct. JCI Insight, 2 (3) e87499, e87499. doi: 10.1172/jci.insight.87499
Sotillo, Javier, Doolan, Denise and Loukas, Alex (2017). Recent advances in proteomic applications for schistosomiasis research: potential clinical impact. Expert Review of Proteomics, 14 (2), 171-183. doi: 10.1080/14789450.2017.1271327
Burel, Julie G., Apte, Simon H., McCarthy, James S. and Doolan, Denise L. (2016). Plasmodium vivax but not Plasmodium falciparum blood-stage infection in humans is associated with the expansion of a CD8+T cell population with cytotoxic potential. PLoS Neglected Tropical Diseases, 10 (12) e0005031, e0005031. doi: 10.1371/journal.pntd.0005031
Proietti, Carla, Zakrzewski, Martha, Watkins, Thomas S., Berger, Bernard, Hasan, Shihab, Ratnatunga, Champa N., Brion, Marie-Jo, Crompton, Peter D., Miles, John J., Doolan, Denise L. and Krause, Lutz (2016). Mining, visualizing and comparing multidimensional biomolecular data using the Genomics Data Miner (GMine) web-server. Scientific Reports, 6 (1) 38178. doi: 10.1038/srep38178
de Oca, Marcela Montes, Kumar, Rajiv, Rivera, Fabian de Labastida, Amante, Fiona H., Sheel, Meru, Faleiro, Rebecca J., Bunn, Patrick T., Best, Shannon E., Beattie, Lynette, Ng, Susanna S., Edwards, Chelsea L., Boyle, Glen M., Price, Ric N., Anstey, Nicholas M., Loughland, Jessica R., Burel, Julie, Doolan, Denise L., Haque, Ashraful, McCarthy, James S. and Engwerda, Christian R. (2016). Type I interferons regulate immune responses in humans with blood-stage Plasmodium falciparum infection. Cell Reports, 17 (2), 399-412. doi: 10.1016/j.celrep.2016.09.015
Burel, Julie G., Apte, Simon H., Groves, Penny L., Klein, Kerenaftali, McCarthy, James S. and Doolan, Denise L. (2016). Reduced Plasmodium parasite burden associates with CD38+ CD4+ T cells displaying cytolytic potential and impaired IFN-γ production. PLoS Pathogens, 12 (9) e1005839, e1005839. doi: 10.1371/journal.ppat.1005839
Raja, Amber I., Cai, Yeping, Reiman, Jennifer M., Groves, Penny, Chakravarty, Sumana, McPhun, Virginia, Doolan, Denise L., Cockburn, Ian, Hoffman, Stephen L., Stanisic, Danielle I. and Good, Michael F. (2016). Chemically attenuated blood-stage Plasmodium yoelii parasites induce long-lived and strain-transcending protection. Infection and Immunity, 84 (8), 2274-2288. doi: 10.1128/IAI.00157-16
Hickey, Bradley W, Lumsden, Joanne M, Reyes, Sharina, Sedegah, Martha, Hollingdale, Michael R, Freilich, Daniel A, Luke, Thomas C, Charoenvit, Yupin, Goh, Lucy M, Berzins, Mara P, Bebris, Lolita, Sacci, John B, De La Vega, Patricia, Wang, Ruobing, Ganeshan, Harini, Abot, Esteban N, Carucci, Daniel J, Doolan, Denise L, Brice, Gary T, Kumar, Anita, Aguiar, Joao, Nutman, Thomas B, Leitman, Susan F, Hoffman, Stephen L, Epstein, Judith E and Richie, Thomas L (2016). Mosquito bite immunization with radiation-attenuated Plasmodium falciparum sporozoites: safety, tolerability, protective efficacy and humoral immunogenicity. Malaria Journal, 15 (1) 377, 1-18. doi: 10.1186/s12936-016-1435-y
Skinner-Adams, Tina S., Sumanadasa, Subathdrage D.M., Fisher, Gillian M., Davis, Rohan A., Doolan, Denise L. and Andrews, Katherine T. (2016). Defining the targets of antiparasitic compounds. Drug Discovery Today, 21 (5), 725-39. doi: 10.1016/j.drudis.2016.01.002
Loughland, Jessica R., Minigo, Gabriela, Burel, Julie, Tipping, Peta E., Piera, Kim A., Amante, Fiona H., Engwerda, Christian R., Good, Michael F., Doolan, Denise L., Anstey, Nicholas M., McCarthy, James S. and Woodberry, Tonia (2016). Profoundly reduced CD1c+ myeloid dendritic cell HLA-DR and CD86 expression and increased tumor necrosis factor production in experimental human blood-stage malaria infection. Infection and Immunity, 84 (5), 1403-1412. doi: 10.1128/IAI.01522-15
Tan, IB, Chang, Ellen T., Chen, Chien-Jen, Hsu, Wan-Lun, Chien, Yin-Chu, Hildesheim, Allan, McKay, James D., Gaborieau, Valerie, Kaderi, Mohamed Arifin Bin, Purnomosari, Dewajani, Voegele, Catherine, LeCalvez-Kelm, Florence, Byrnes, Graham, Brennan, Paul, Devi, Beena, Li, L., Zhang, Y., Fan, Y., Sun, K., Du, Z., Sun, H., Chan, A. T., Tsao, S. W., Zeng, Y. X., Tao, Q., Busson, Pierre, Lhuillier, Claire, Morales, Olivier, Mrizak, Dhafer ... Haryana, Sofia Mubarika (2016). Proceedings of the 7th Biannual International Symposium on Nasopharyngeal Carcinoma 2015 : Yogyakarta, Indonesia. 4-6 June 2015. BMC Proceedings, 10 (S1) 1. doi: 10.1186/s12919-016-0001-5
de Sousa, Karina P. and Doolan, Denise L. (2016). Immunomics: a 21st century approach to vaccine development for complex pathogens. Parasitology, 143 (2), 236-244. doi: 10.1017/S0031182015001079
Sedaghat, Bita, Stephenson, Rachel J., Giddam, Ashwini Kumar, Eskandari, Sharareh, Apte, Simon H., Pattinson, David J., Doolan, Denise L. and Toth, Istvan (2016). Synthesis of mannosylated lipopeptides with receptor targeting properties. Bioconjugate Chemistry, 27 (3), 533-548. doi: 10.1021/acs.bioconjchem.5b00547
Chandrudu, Saranya, Skwarczynski, Mariusz, Pattinson, David, Apte, Simon H., Doolan, Denise L. and Toth, Istvan (2016). Synthesis and immunological evaluation of peptide-based vaccine candidates against malaria. Biochemical Compounds, 4 (1). doi: 10.7243/2052-9341-4-1
Apte, Simon H., Stephenson, Rachel J., Simerska, Pavla, Groves, Penny L., Aljohani, Salwa, Eskandari, Sharareh, Toth, Istvan and Doolan, Denise L. (2016). Systematic evaluation of self-adjuvanting lipopeptide nano-vaccine platforms for the induction of potent CD8+ T-cell responses. Nanomedicine, 11 (2), 137-152. doi: 10.2217/nnm.15.184
Burel, Julie G., Apte, Simon H. and Doolan, Denise L. (2016). Systems approaches towards molecular profiling of human immunity. Trends in Immunology, 37 (1), 53-67. doi: 10.1016/j.it.2015.11.006
Davies, D Huw, Duffy, Patrick, Bodmer, Jean-Luc, Felgner, Philip L. and Doolan, Denise L. (2015). Large screen approaches to identify novel malaria vaccine candidates. Vaccine, 33 (52), 7496-7505. doi: 10.1016/j.vaccine.2015.09.059
Eskandari, Sharareh, Stephenson, Rachel J., Fuaad, Abdullah Ahmad, Apte, Simon H., Doolan, Denise L. and Toth, Istvan (2015). Synthesis and characterisation of self-assembled and self-adjuvanting asymmetric multi-epitope lipopeptides of ovalbumin. Chemistry - A European Journal, 21 (3), 1251-1261. doi: 10.1002/chem.201404997
Burel, Julie G., Apte, Simon H. and Doolan, Denise L. (2015). Development of a cytokine-secreting-based assay for the identification, sorting and transcriptomic analysis of polyfunctional human T cells. European Cytokine Network, 26 (4), 67-72. doi: 10.1684/ecn.2015.0369
Pearson, Mark S, Becker, Luke, Driguez, Patrick, Young, Neil D, Gaze, Soraya, Mendes, Tiago, Li, Xiao-Hong, Doolan, Denise L, Midzi, Nicholas, Mduluza, Takafira, McManus, Donald P, Wilson, R Alan, Bethony, Jeffrey M, Nausch, Norman, Mutapi, Francisca, Felgner, Philip L and Loukas, Alex (2015). Of monkeys and men: immunomic profiling of sera from humans and non-human primates resistant to schistosomiasis reveals novel potential vaccine candidates. Frontiers in immunology, 6 (MAY) 213, 1-13. doi: 10.3389/fimmu.2015.00213
Tribolet, Leon, Cantacessi, Cinzia, Pickering, Darren A., Navarro, Severine, Doolan, Denise L., Trieu, Angela, Fei, Huang, Chao, Yang, Hofmann, Andreas, Gasser, Robin B., Giacomin, Paul R. and Loukas, Alex (2015). Probing of a human proteome microarray with a recombinant pathogen protein reveals a novel mechanism by which hookworms suppress B-cell receptor signaling. The Journal of Infectious Diseases, 211 (3), 416-425. doi: 10.1093/infdis/jiu451
Proietti, Carla and Doolan, Denise L. (2015). The case for a rational genome-based vaccine against malaria. Frontiers in Microbiology, 5 (DEC) 741, 1-19. doi: 10.3389/fmicb.2014.00741
Eskandari, Sharareh, Stephenson, Rachel J., Fuaad, Abdullah Ahmad, Apte, Simon H., Doolan, Denise L. and Toth, Istvan (2015). Synthesis and characterisation of self-assembled and self-adjuvanting asymmetric multi-epitope lipopeptides of ovalbumin. Chemistry: A European Journal, 21 (3), 1251-1261. doi: 10.1002/chem.201404997
Driguez, Patrick, McWilliam, Hamish E. G., Gaze, Soraya, Piedrafita, David, Pearson, Mark S., Nakajima, Rie, Duke, Mary, Trieu, Angela, Doolan, Denise L., Cardoso, Fernanda C., Jasinskas, Algis, Gobert, Geoffrey N., Felgner, Philip L., Loukas, Alex, Meeusen, Els and McManus, Donald P. (2015). Specific humoral response of hosts with variable schistosomiasis susceptibility. Immunology and Cell Biology, 94 (1), 52-65. doi: 10.1038/icb.2015.61
Driguez, Patrick, Li, Yuesheng, Gaze, Soraya, Pearson, Mark S., Nakajima, Rie, Trieu, Angela, Doolan, Denise L., Felgner, Philip L., Hou, Xunya, Cardoso, Fernanda C., Jasinskas, Algis, Gobert, Geoffrey, Loukas, Alexander C. and McManus, Donald P. (2015). Antibody signatures reflect different disease pathologies in schistosomiasis japonica. Journal of Infectious Diseases, 213 (1), 122-130. doi: 10.1093/infdis/jiv356
Gaze, Soraya, Driguez, Patrick, Pearson, Mark S., Mendes, Tiago, Doolan, Denise L., Trieu, Angela, McManus, Donald P., Gobert, Geoffrey N., Periago, Maria Victoria, Correa Oliveira, Rodrigo, Cardoso, Fernanda C., Oliveira, Guilherme, Nakajima, Rie, Jasinskas, Al, Hung, Chris, Liang, Li, Pablo, Jozelyn, Bethony, Jeffrey M., Felgner, Philip L. and Loukas, Alex (2014). An immunomics approach to schistosome antigen discovery: antibody signatures of naturally resistant and chronically infected individuals from endemic areas. PLoS Pathogens, 10 (3) e1004033, e1004033.1-e1004033.16. doi: 10.1371/journal.ppat.1004033
Schussek, Sophie, Trieu, Angela and Doolan, Denise L. (2014). Genome- and proteome-wide screening strategies for antigen discovery and immunogen design. Biotechnology Advances, 32 (2), 403-414. doi: 10.1016/j.biotechadv.2013.12.006
Doolan, Denise L., Apte, Simon H. and Proietti, Carla (2014). Genome-based vaccine design: The promise for malaria and other infectious diseases. International Journal for Parasitology, 44 (12), 901-913. doi: 10.1016/j.ijpara.2014.07.010
Tarigo, Jaime L., Scholl, Elizabeth H., Bird, David McK., Brown, Corrie C., Cohn, Leah A., Dean, Gregg A., Levy, Michael G., Doolan, Denise L., Trieu, Angela, Nordone, Shila K., Felgner, Philip L., Vigil, Adam and Birkenheuer, Adam J. (2013). Correction: a novel candidate vaccine for Cytauxzoonosis inferred from comparative apicomplexan genomics. PLoS One, 8 (10) e71233, 1-9. doi: 10.1371/annotation/943b121e-343b-4df1-a06b-7f8a205a057d
Apte, Simon H., Redmond, Andrew M., Groves, Penny L., Schussek, Sophie, Pattinson, David J. and Doolan, Denise L. (2013). Subcutaneous cholera toxin exposure induces potent CD103+ dermal dendritic cell activation and migration. European Journal of Immunology, 43 (10), 2707-2717. doi: 10.1002/eji.201343475
Schussek, Sophie, Trieu, Angela, Apte, Simon H., Sidney, John, Sette, Alessandro and Doolan, Denise L. (2013). Immunization with apical membrane antigen 1 confers sterile infection-blocking immunity against Plasmodium sporozoite challenge in a rodent model. Infection and Immunity, 81 (10), 3586-3599. doi: 10.1128/IAI.00544-13
Schussek, Sophie, Groves, Penny L., Apte, Simon H. and Doolan, Denise L. (2013). Highly sensitive quantitative real-time PCR for the detection of Plasmodium liver-stage parasite burden following low-dose sporozoite challenge. PLoS One, 8 (10) e77811, e77811.1-e77811.10. doi: 10.1371/journal.pone.0077811
Tarigo, Jaime L., Scholl, Elizabeth H., Bird, David McK, Brown, Corrie C., Cohn, Leah A., Dean, Gregg A., Levy, Michael G., Doolan, Denise L., Trieu, Angela, Nordone, Shila K., Felgner, Philip L., Vigil, Adam and Birkenheuer, Adam J. (2013). A novel candidate vaccine for Cytauxzoonosis inferred from comparative apicomplexan genomics. PLoS One, 8 (8) e71233, 1-9. doi: 10.1371/journal.pone.0071233
Sedegah, Martha, Kim, Yohan, Ganeshan, Harini, Huang, Jun, Belmonte, Maria, Abot, Esteban, Banania, Jo Glenna, Farooq, Fouzia, McGrath, Shannon, Peters, Bjoern, Sette, Alessandro, Soisson, Lorraine, Diggs, Carter, Doolan, Denise L, Tamminga, Cindy, Villasante, Eileen, Hollingdale, Michael R and Richie, Thomas L. (2013). Identification of minimal human MHC-restricted CD8+ T-cell epitopes within the Plasmodium falciparum circumsporozoite protein (CSP). Malaria Journal, 12 (1) 185. doi: 10.1186/1475-2875-12-185
Chuang, Ilin, Sedegah, Martha, Cicatelli, Susan, Spring, Michele, Polhemus, Mark, Tamminga, Cindy, Patterson, Noelle, Guerrero, Melanie, Bennett, Jason W, McGrath, Shannon, Ganeshan, Harini, Belmonte, Maria, Farooq, Fouzia, Abot, Esteban, Banania, Jo Glenna, Huang, Jun, Newcomer, Rhonda, Rein, Lisa, Litilit, Dianne, Richie, Nancy O, Wood, Chloe, Murphy, Jittawadee, Sauerwein, Robert, Hermsen, Cornelus C, McCoy, Andrea J, Kamau, Edwin, Cummings, James, Komisar, Jack, Sutamihardja, Awalludin ... Richie, Thomas L (2013). DNA prime/Adenovirus boost malaria vaccine encoding P. falciparum CSP and AMA1 induces sterile protection associated with cell-mediated immunity. PLoS One, 8 (2) e55571, 1-15. doi: 10.1371/journal.pone.0055571
Doolan, Denise (2012). Editorial. International Journal for Parasitology: Parasites and Wildlife, 1, 1-1. doi: 10.1016/j.ijppaw.2012.07.001
Richie, Thomas L, Charoenvit, Yupin, Wang, Ruobing, Epstein, Judith E, Hedstrom, Richard C, Kumar, Sanjai, Luke, Thomas C, Freilich, Daniel A, Aguiar, Joao C, Sacci, John B, Sedegah, Martha, Nosek, Ronald A, De La Vega, Patricia, Berzins, Mara P, Majam, Victoria F, Abot, Esteban N, Ganeshan, Harini, Richie, Nancy O, Banania, Jo Glenna, Baraceros, Maria Fe B, Geter, Tanya G, Mere, Robin, Bebris, Lolita, Limbach, Keith, Hickey, Bradley W, Lanar, David E, Ng, Jennifer, Shi, Meng, Hobart, Peter M ... Hoffman, Stephen L (2012). Clinical trial in healthy malaria-naïve adults to evaluate the safety, tolerability, immunogenicity and efficacy of MuStDO5, a five-gene, sporozoite/hepatic stage Plasmodium falciparum DNA vaccine combined with escalating dose human GM-CSF DNA. Human Vaccines and Immunotherapeutics, 8 (11), 1564-1584. doi: 10.4161/hv.22129
Doolan, Denise L. and Apte, Simon H. (2012). Addressing the bottleneck at clinical testing of candidate malaria vaccines. Pathogens and Global Health, 106 (6). doi: 10.1179/2047772412Z.00000000081
Apte, Simon H., Groves, Penny L., Skwarczynski, Mariusz, Fujita, Yoshio, Chang, Chenghung, Toth, Istvan and Doolan, Denise L. (2012). Vaccination with lipid core peptides fails to induce epitope-specific T cell responses but confers non-specific protective immunity in a malaria model.. PLoS One, 7 (8 Article. No.e40928) e40928, e40928. doi: 10.1371/journal.pone.0040928
Bruder, Joseph T., Semenova, Elena, Chen, Ping, Limbach, Keith, Patterson, Noelle B., Stefaniak, Maureen E., Konovalova, Svetlana, Thomas, Charlie, Hamilton, Melissa, King, C. Richter, Richie, Thomas L. and Doolan, Denise L. (2012). Correction: Modification of Ad5 hexon hypervariable regions circumvents pre-existing Ad5 neutralizing antibodies and induces protective immune responses. PLoS One, 7 (5). doi: 10.1371/annotation/c110beed-3cac-48db-9039-ba4498d5db50
Bruder, Joseph T., Semenova, Elena, Chen, Ping, Limbach, Keith, Patterson, Noelle B., Stefaniak, Maureen E., Konovalova, Svetlana, Thomas, Charlie, Hamilton, Melissa, King, C. Richter, Richie, Thomas L. and Doolan, Denise L. (2012). Modification of Ad5 hexon hypervariable regions circumvents pre-existing Ad5 neutralizing antibodies and induces protective immune responses. PLoS One, 7 (4) e33920, 1-13. doi: 10.1371/journal.pone.0033920
Guinovart, Caterina, Dobaño, Carlota, Bassat, Quique, Nhabomba, Augusto, Quintó, Llorenç, Manaca, Maria Nélia, Aguilar, Ruth, Rodríguez, Mauricio H, Barbosa, Arnoldo, Aponte, John J, Mayor, Alfredo G, Renom, Montse, Moraleda, Cinta, Roberts, David J, Schwarzer, Evelin, Le Souëf, Peter N, Schofield, Louis, Chitnis, Chetan E, Doolan, Denise L and Alonso, Pedro L (2012). The role of age and exposure to Plasmodium falciparum in the rate of acquisition of naturally acquired immunity: a randomized controlled trial. PLoS One, 7 (3) e32362, 1-11. doi: 10.1371/journal.pone.0032362
Quelhas, Diana, Puyol, Laura, Quintó, Llorenç, Nhampossa, Tacilta, Serra-Casas, Elisa, Macete, Eusébio, Aide, Pedro, Sanz, Sergi, Aponte, John J, Doolan, Denise L, Alonso, Pedro L, Menéndez, Clara and Dobaño, Carlota (2012). Intermittent preventive treatment with sulfadoxine-pyrimethamine does not modify plasma cytokines and chemokines or intracellular cytokine responses to Plasmodium falciparum in Mozambican children. BMC Immunology, 13 (1) 5, 1-18. doi: 10.1186/1471-2172-13-5
Doolan, Denise L. and Spithill, Terry (2011). Editorial. International Journal for Parasitology: Drugs and Drug Resistance, 1 (1), 1-1. doi: 10.1016/j.ijpddr.2011.09.001
Cardoso, Fernanda C., Roddick, Joanne S., Groves, Penny and Doolan, Denise L. (2011). Evaluation of approaches to identify the targets of cellular immunity on a proteome-wide scale. Plos One, 6 (11) e27666, e27666.1-e27666.14. doi: 10.1371/journal.pone.0027666
Barry, Alyssa E., Trieu, Angela, Fowkes, Freya J. I., Pablo, Jozelyn, Kalantari-Dehaghi, Matthew, Jasinskas, Algis, Tan, Xiaolin, Kayala, Matthew A., Tavul, Livingstone, Siba, Peter M., Day, Karen P., Baldi, Pierre, Felgner, Philip L. and Doolan, Denise L. (2011). The stability and complexity of antibody responses to the major surface antigen of plasmodium falciparum are associated with age in a malaria endemic area. Molecular and Cellular Proteomics, 10 (11) M111.008326, 1-12. doi: 10.1074/mcp.M111.008326
Tamminga, Cindy, Sedegah, Martha, Regis, David, Chuang, Ilin, Epstein, Judith E, Spring, Michele, Mendoza-Silveiras, Jose, McGrath, Shannon, Maiolatesi, Santina, Reyes, Sharina, Steinbeiss, Victoria, Fedders, Charlotte, Smith, Kathryn, House, Brent, Ganeshan, Harini, Lejano, Jennylynn, Abot, Esteban, Banania, Glenna J, Sayo, Renato, Farooq, Fouzia, Belmonte, Maria, Murphy, Jittawadee, Komisar, Jack, Williams, Jackie, Shi, Meng, Brambilla, Donald, Manohar, Nalini, Richie, Nancy O, Wood, Chloe ... Richie, Thomas L (2011). Adenovirus-5-vectored P. falciparum vaccine expressing CSP and AMA1. Part B: safety, immunogenicity and protective efficacy of the CSP component. PLoS One, 6 (10) e25868, 1-20. doi: 10.1371/journal.pone.0025868
Sedegah, Martha, Tamminga, Cindy, McGrath, Shannon, House, Brent, Ganeshan, Harini, Lejano, Jennylynn, Abot, Esteban, Banania, Glenna J, Sayo, Renato, Farooq, Fouzia, Belmonte, Maria, Manohar, Nalini, Richie, Nancy O, Wood, Chloe, Long, Carole A, Regis, David, Williams, Francis T, Shi, Meng, Chuang, Ilin, Spring, Michele, Epstein, Judith E, Mendoza-Silveiras, Jose, Limbach, Keith, Patterson, Noelle B, Bruder, Joseph T, Doolan, Denise L, King, C Richter, Soisson, Lorraine, Diggs, Carter ... Richie, Thomas L (2011). Adenovirus 5-vectored P. falciparum vaccine expressing CSP and AMA1. Part A: safety and immunogenicity in seronegative adults. PLoS One, 6 (10) e24586, 1-22. doi: 10.1371/journal.pone.0024586
Apte, Simon H., Groves, Penny L., Roddick, Joanne S., P da Hora, Vanusa and Doolan, Denise L. (2011). High-throughput multi-parameter flow-cytometric analysis from micro-quantities of plasmodium-infected blood. International Journal for Parasitology, 41 (12), 1285-94. doi: 10.1016/j.ijpara.2011.07.010
Loukas, Alex, Gaze, Soraya, Mulvenna, Jason P., Gasser, Robin B, Brindley, Paul J., Doolan, Denise L., Bethony, Jeffrey M., Jones, Malcolm K., Gobert, Geoffrey N., Driguez, Patrick, McManus, Donald P. and Hotez, Peter J. (2011). Vaccinomics for the major blood feeding helminths of humans. OMICS: A Journal of Integrative Biology, 15 (9), 567-577. doi: 10.1089/omi.2010.0150
Trieu, Angela, Kayala, Matthew A., Burk, Chad, Molina, Douglas M., Freilich, Daniel A., Richie, Thomas L., Baldi, Pierre, Felgner, Philip L. and Doolan, Denise L. (2011). Sterile protective immunity to malaria is associated with a panel of novel P. falciparum antigens. Molecular and Cellular Proteomics, 10 (9) M111.007948, 1-15. doi: 10.1074/mcp.M111.007948
Campo, Joseph J., Whitman, Timothy J., Freilich, Daniel, Burgess, Timothy H., Martin, Gregory J. and Doolan, Denise L. (2011). Toward a surrogate marker of malaria exposure: Modeling longitudinal antibody measurements under outbreak conditions. PLoS One, 6 (7) e21826, 1-6. doi: 10.1371/journal.pone.0021826
Dodoo, Daniel, Hollingdale, Michael R., Anum, Dorothy, Koram, Kwadwo A., Gyan, Ben, Akanmori, Bartholomew D., Ocran, Josephine, Adu-Amankwah, Susan, Geneshan, Harini, Abot, Esteban, Legano, Jennylyn, Banania, Glenna, Sayo, Renato, Brambilla, Donald, Kumar, Sanjai, Doolan, Denise L., Rogers, William O., Epstein, Judith, Richie, Thomas L. and Sedegah, Martha (2011). Measuring naturally acquired immune responses to candidate malaria vaccine antigens in Ghanaian adults. Malaria Journal, 10 (1) 168. doi: 10.1186/1475-2875-10-168
Douradinha, Bruno and Doolan, Denise L. (2011). Harnessing immune responses against Plasmodium for rational vaccine design. Trends in Parasitology, 27 (6), 274-283. doi: 10.1016/j.pt.2011.01.002
da Hora, Vanusa P., Conceição, Fabricio R., Dellagostin, Odir A. and Doolan, Denise L. (2011). Non-toxic derivatives of LT as potent adjuvants. Vaccine, 29 (8), 1538-1544. doi: 10.1016/j.vaccine.2010.11.091
Doolan, Denise L. (2011). Plasmodium immunomics. International Journal for Parasitology, 41 (1), 3-20. doi: 10.1016/j.ijpara.2010.08.002
Good, Michael F. and Doolan, Denise L. (2010). Malaria vaccine design: Immunological Considerations. Immunity, 33 (4), 555-566. doi: 10.1016/j.immuni.2010.10.005
Sedegah, Martha, Kim, Yohan, Peters, Bjoern, McGrath, Shannon, Ganeshan, Harini, Lejano, Jennylynn, Abot, Esteban, Banania, Glenna, Belmonte, Maria, Sayo, Renato, Farooq, Fouzia, Doolan, Denise L., Regis, David, Tamminga, Cindy, Chuang, Ilin, Bruder, Joseph T., King, C. Richter, Ockenhouse, Christian F., Faber, Bart, Remarque, Edmond, Hollingdale, Michael R., Richie, Thomas L. and Sette, Alessandro (2010). Identification and localization of minimal MHC-restricted CD8+ T cell epitopes within the Plasmodium falciparum AMA1 protein. Malaria Journal, 9 (1) 241. doi: 10.1186/1475-2875-9-241
Redmond, A. M. and Doolan, D. L. (2010). The Australasian contribution to malaria vaccine development. Parasite Immunology, 32 (8), 607-622. doi: 10.1111/j.1365-3024.2010.01229.x
Apte, Simon H, Groves, Penny, Olver, Stuart, Baz, Adriana, Doolan, Denise L, Kelso, Anne and Kienzle, Norbert (2010). IFN-gamma inhibits IL-4-induced type 2 cytokine expression by CD8 T cells in vivo and modulates the anti-tumor response. Journal of Immunology, 185 (2), 998-1004. doi: 10.4049/jimmunol.0903372
Bruder, Joseph T., Stefaniak, Maureen E., Patterson, Noelle B., Chen, Ping, Konovalova, Svetlana, Limbach, Keith, Campo, Joseph J., Ettyreddy, Damodar, Li, Sheng, Dubovsky, Filip, Richie, Thomas L., King, C. Richter, Long, Carole A. and Doolan, Denise L. (2010). Adenovectors induce functional antibodies capable of potent inhibition of blood stage malaria parasite growth. Vaccine, 28 (18), 3201-3210. doi: 10.1016/j.vaccine.2010.02.024
Crompton, Peter D., Kayala, Matthew A., Traore, Boubacar, Kayentao, Kassoum, Ongoiba, Aissata, Weiss, Greta E., Molina, Douglas M., Burk, Chad R., Waisberg, Michael, Jasinskas, Algis, Tan, Xiaolin, Doumbo, Safiatou, Doumtabe, Didier, Kone, Younoussou, Narum, David L., Liang, Xiaowu, Doumbo, Ogobara K., Miller, Louis H., Doolan, Denise L., Baldi, Pierre, Felgner, Philip L. and Pierce, Susan K. (2010). A prospective analysis of the Ab response to Plasmodium falciparum before and after a malaria season by protein microarray. Proceedings of the National Academy of Sciences of the United States of America, 107 (15), 6958-6963. doi: 10.1073/pnas.1001323107
Sedegah, Martha, Rogers, William O., Belmonte, Maria, Belmonte, Arnel, Banania, Glenna, Patterson, Noelle B., Rusalov, Denis, Ferrari, Marilyn, Richie, Thomas L. and Doolan, Denise L. (2010). Vaxfectin® enhances both antibody and in vitro T cell responses to each component of a 5-gene Plasmodium falciparum plasmid DNA vaccine mixture administered at low doses. Vaccine, 28 (17), 3055-3065. doi: 10.1016/j.vaccine.2009.10.044
Dobaño, C., Weiss, W. R., Kamrud, K. I., Chulay, J. D., Smith, J., Carucci, D. J. and Doolan, D. L. (2010). Alphavirus replicon particles are highly immunogenic in the murine malaria model by homologous or heterologous immunization. Open Vaccine Journal, 3 (1), 27-37.
Driguez, P, Doolan, DL, Loukas, A, Felgner, PL and McManus, DP (2010). Schistosomiasis vaccine discovery using immunomics. Parasites and Vectors, 3 (1) 4, 4 - 1-4 - 5. doi: 10.1186/1756-3305-3-4
Doolan, Denise L. (2010). Special issue on malaria vaccine development. Human Vaccines, 6 (1). doi: 10.4161/hv.6.1.10703
Jiang, George, Shi, Meng, Conteh, Solomon, Richie, Nancy, Banania, Glenna, Geneshan, Harini, Valencia, Anais, Singh, Priti, Aguiar, Joao, Limbach, Keith, Kamrud, Kurt I., Rayner, Jonathan, Smith, Jonathan, Bruder, Joseph T., King, C. Richter, Tsuboi, Takafumi, Takeo, Satoru, Endo, Yaeta, Doolan, Denise L., Richie, Thomas L. and Weiss, Walter R. (2009). Sterile protection ,against Plasmodium knowlesi in rhesus monkeys from a malaria vaccine: Comparison of heterologous prime boost strategies. PloS one, 4 (8) e6559, e6559 -1-e6559 -12. doi: 10.1371/journal.pone.0006559
Woodberry, Tonia, Pinzon-Charry, Alberto, Piera, Kim A., Panpisutchai, Yawalak, Engwerda, Christian R., Doolan, Denise L., Salwati, Ervi, Kenangalem, Enny, Tjitra, Emiliana, Price, Ric N., Good, Michael F. and Anstey, Nicholas M. (2009). Human T cell recognition of the blood stage antigen Plasmodium hypoxanthine guanine xanthine phosphoribosyl transferase (HGXPRT) in acute malaria. Malaria Journal, 8 (1) 122, 122.1-122.10. doi: 10.1186/1475-2875-8-122
Dobañoa, Carlota, Sedegah, Martha, Rogers, William O., Kumar, Sanjai, Zheng, Hong, Hoffman, Stephen L. and Doolan, Denise (2009). Plasmodium: Mammalian codon optimization of malaria plasmid DNA vaccines enhances antibody responses but not T cell responses nor protective immunity. Experimental Parasitology, 122 (2), 112-123. doi: 10.1016/j.exppara.2009.02.010
Vaughan, K., Blythe, M., Greenbaum, J., Zhang, Q., Peters, B., Doolan, D.L. and Sette, A. (2009). Meta-analysis of immune epitope data for all Plasmodia: overview and applications for malarial immunobiology and vaccine-related issues. Parasite Immunology, 31 (2), 78-97. doi: 10.1111/j.1365-3024.2008.01077.x
Doolan, Denise L., Dobano, Carlota and Baird, J. Kevin (2009). Acquired immunity to malaria. Clinical Microbiology Reviews, 22 (1), 13-26. doi: 10.1128/CMR.00025-08
Doolan, Denise L., Mu, Yunxiang, Una, Berkay, Sundaresh, Suman, Hirst, Siddiqua, Valdez, Conrad and et al. (2008). Profiling humoral immune responses to P. falciparum infection with protein microarrays. Proteomics, 8 (22), 4680-4694. doi: 10.1002/pmic.200800194
Doolan, Denise L. (2008). The path of discovery. Human Vaccines, 4 (5), 324-327. doi: 10.4161/hv.4.5.6707
Regis, David P., Dobaño, Carlota, Quiñones-Olson, Paola, Liang, Xiaowu, Graber, Norma L., Stefaniak, Maureen E., Campo, Joseph J., Carucci, Daniel J., Roth, David A., He, Huaping, Felgner, Philip L. and Doolan, Denise L. (2008). Transcriptionally active PCR for antigen identification and vaccine development: In vitro genome-wide screening and in vivo immunogenicity. Molecular and Biochemical Parasitology, 158 (1), 32-45. doi: 10.1016/j.molbiopara.2007.11.009
Dobano, C., Weiss, W. R., Kamrud, K. I., Chulay, J. D., Smith, J., Carucci, D. J. and Doolan, D. L. (2008). Alphavirus replicon particles are highly immunogenic in the murine malaria model by homologous or heterologous immunization. The Open Vaccine Journal, 1, 27-37.
Doolan, Denise L. and Stewart, V. Ann (2007). Status of malaria vaccine R&D in 2007. Expert Review of Vaccines, 6 (6), 903-905. doi: 10.1586/14760584.6.6.903
Jiang, George, Charoenvit, Yupin, Moreno, Alberto, Baraceros, Maria F., Banania, Glenna, Richie, Nancy, Abot, Steve, Ganeshan, Harini, Fallarme, Victoria, Patterson, Noelle B., Geall, Andrew, Weiss, Walter R., Strobert, Elizabeth, Caro-Aquilar, Ivette, Lanar, David E., Saul, Allan, Martin, Laura B., Gowda, Kalpana, Morrissette, Craig R., Kaslow, David C., Carucci, Daniel J., Galinski, Mary R. and Doolan, Denise L. (2007). Induction of multi-antigen multi-stage immune responses against Plasmodium falciparum in rhesus monkeys, in the absence of antigen interference, with heterologous DNA prime/poxvirus boost immunization. Malaria Journal, 6 (1) 135, 135-152. doi: 10.1186/1475-2875-6-135
Brice, Gary T., Dobano, Carlota, Sedegah, Martha, Stefaniak, Maureen, Graber, Norma L., Campo, Joseph J., Carucci, Daniel J. and Doolan, Denise L. (2007). Extended immunization intervals enhance the immunogenicity and protective efficacy of plasmid DNA vaccines. Microbes and Infection, 9 (12-13), 1439-1446. doi: 10.1016/j.micinf.2007.07.009
Dobano, Carlota, Widera, Georg, Rabussay, Dietmar and Doolan, Denise L. (2007). Enhancement of antibody and cellular immune responses to malaria DNA vaccines by in vivo electroporation. Vaccine, 25 (36), 6635-6645. doi: 10.1016/j.vaccine.2007.06.036
Dobañoa, Carlota, Rogersa, William O., Gowdaa , Kalpana and Doolana, Denise L. (2007). Targeting antigen to MHC Class I and Class II antigen presentation pathways for malaria DNA vaccines. Immunology Letters, 111 (2), 92-102. doi: 10.1016/j.imlet.2007.05.007
Li, Shengqiang, Locke, Emily, Bruder, Joseph, Clarke, David, Doolan, Denise L., Havenga, Menzo J. E., Hill, Adrian V. S., Liljestrom, Peter, Monath, Thomas P., Naimi, Hussein Y., Ockenhouse, Christian, Tang, De-chu C., Van Kampen, Kent R., Viret, Jean-Francois, Zavala, Fidel and Dubovsky, Filip (2007). Viral vectors for malaria vaccine development. Vaccine, 25 (14), 2567-2574. doi: 10.1016/j.vaccine.2006.07.035
Dobano, C., McTague, A., Sette, A., Hoffman, S. L., Rogers, W. O. and Doolan, D. L. (2007). Mutating the Anchor Residues Associated with MHC Binding Inhibits and Deviates CD8+ T cell Mediated Protective Immunity Against Malaria. Molecular Immunology, 44 (9), 2235-2248. doi: 10.1016/j.molimm.2006.11.003
Good, Michael F. and Doolan, Denise L. (2007). Malaria's journey through the lymph node. Nature Medicine, 13 (9), 1023-1024. doi: 10.1038/nm0907-1015
Dobano, C. and Doolan, D.L. (2007). Identification of minimal CD8+ and CD4+ T cell epitopes in the Plasmodium yoelii hepatocyte erythrocyte protein 17 kDa. Molecular Immunology, 44 (11), 3037-3048. doi: 10.1016/j.molimm.2007.01.001
Sedegah, Martha, Rogers, William O., Belmonte, Arnel, Belmonte, Maria, Banania, Glenna, Patterson, Noelle, Ferrari, Marilyn, Kaslow, David C., Carucci, Daniel J., Richie, Thomas L. and Doolan, Denise L. (2006). Vaxfectin™ enhances immunogenicity and protective efficacy of P. yoelii circumsporozoite DNA vaccine. Vaccine, 24 (11), 1921-1927. doi: 10.1016/j.vaccine.2005.10.041
Doolan, Denise L., Freilich, Daniel A., Brice, Gary T., Burgess, Timothy H., Berzins, Mara P., Bull, Robert L., Graber, Norma L., Dabbs, Jason L., Shatney, Lori L., Blazes, David L., Bebris, Lolita M., Malone, Maria F., Eisold, John F., Mateczun, Alfred J. and Martin, Gregory J. (2006). The US capitol bioterrorism anthrax exposures: Clinical epidemiological and immunological characteristics. Journal of Infectious Diseases, 195 (2), 174-184. doi: 10.1086/510312
Doolan, D. L. and Martinez-Alier, N. (2006). Immune response to pre-erythrocytic stages of malaria parasites. Current Molecular Medicine, 6 (2), 169-185. doi: 10.2174/156652406776055249
Sundaresh, S., Doolan, D. L., Hirst, S., Mu, Y., Unal, B., Davies, H., Felgner, P. and Baldi, P. (2006). Identification of humoral immune responses in protein microarrays using DNA microarray data analysis techniques. Bioinformatics, 22 (14), 1760-1766. doi: 10.1093/bioinformatics/btl162
Charoenvit, Yupin, Brice, Gary T., Bacon, David, Majam, Victoria, Williams, Jackie, Abot, Esteban, Ganeshan, Harini, Sedegah, Martha, Doolan, Denise L., Carucci, Daniel J. and Zimmerman, Daniel H. (2004). A Small Peptide (CEL-1000) Derived from the ß-Chain of the Human Major Histocompatibility Complex Class II Molecule Induces Complete Protection against Malaria in an Antigen-Independent Manner. Antimicrobial agents and chemotherapy, 48 (7), 2455-2463. doi: 10.1128/AAC.48.7.2455-2463.2004
Wang, Ruobing, Epstein, Judith, Charoenvit, Yupin, Baraceros, Fe Maria, Rahardjo, Nancy, Gay, Tanya, Banania, Jo-Glenna, Chattopadhyay, Rana, de la Vega, Patricia, Richie, Thomas L., Tornieporth, Nadia, Doolan, Denise L., Kester, Kent E., Heppner, D. Gray, Norman, Jon, Carucci, Daniel J., Cohen, Joe D. and Hoffman, Stephen L. (2004). Induction in Humans of CD8+ and CD4+ T Cell and Antibody Responses by Sequential Immunization with Malaria DNA and Recombinant Protein. Journal of immunology, 172 (9), 5561-5569. doi: 10.4049/jimmunol.172.9.5561
Doolan, D. L., Aguiar, J. C., Weiss, W. R., Sette, A., Felgner, P. L., Regis, D. P., Quinones-Casas, P., Yates, J. R. III, Blair, P. L., Richie, T. L., Hoffman, S. L. and Carucci, D. J. (2003). Utilization of genomic sequence information to develop malaria vaccines. Journal of experimental biology, 206 (21), 3789-3802. doi: 10.1242/jeb.00615
Doolan, Denise, Southwood, S., Freilich, D. A., Sidney, J., Graber, N. L., Shatney, L., Bebris, L., Florens, L., Dobano, C., Witney, A.A., Apella, E., Hoffman, S. L., Yates, J. R. 3rd, Carucci, D. J. and Sette, A. (2003). Identification of plasmodium falciparum antigens by antigenic analysis of genomic and proteomic data. Proceedings of the National Academy of Sciences of the United States of America, 100 (17), 9952-9957. doi: 10.1073/pnas.1633254100
Brice, Gary T., Graber, Norma L., Carucci, Daniel J. and Doolan, Denise L. (2002). Optimal induction of antigen-specific CD8+ T cell responses requires bystander cell participation. Journal of leukocyte biology, 72 (6), 1164-1171. doi: 10.1189/jlb.72.6.1164
Gramzinski, Robert A., Doolan, Denise L., Sedegah, Martha, Davis, Heather L., Krieg, Arthur M. and Hoffman, Stephen L. (2002). Erratum: Interleukin-12- and gamma interferon-dependent protection against malaria conferred by CpG oligodeoxynucleotide in mice (Infection and Immunity (2001) 69:3 (1643-1649)). Infection and Immunity, 70 (9). doi: 10.1128/IAI.70.9.5338.2002
Sedegah, Martha, Brice, Gary T., Rogers, William O., Doolan, Denise L., Charoenvit, Yupin, Jones, Trevor R., Majam, Victoria F., Belmonte, Arnel, Lu, Minh, Belmonte, Maria, Carucci, Daniel J. and Hoffman, Stephen L. (2002). Persistence of Protective Immunity to Malaria Induced by DNA Priming and Poxvirus Boosting: Characterization of Effector and Memory CD8+-T-Cell Populations. Infection and immunity, 70 (7), 3493-3499. doi: 10.1128/IAI.70.7.3493-3499.2002
Hoffman, Stephen L., Goh, Lucy M. L., Luke, Thomas C., Schneider, Imogene, Le, Thong P., Doolan, Denise L., Sacci, John, De la Vega, Patricia, Dowler, Megan, Paul, Chris, Gordon, Daniel M., Stoute, Jose A., Preston Church, L. W., Sedegah, Martha, Gray Heppner, D., Ripley Ballou, W. and Richie, Thomas L. (2002). Protection of humans against malaria by immunization with radiation-attenuated Plasmodium falciparum sporozoites. Journal of Infectious Diseases, 185 (8), 1155-1164. doi: 10.1086/339409
Doolan, Denise L. and Hoffman, Stephen L. (2002). Nucleic acid vaccines against malaria. Chemical Immunology, 80, 308-321. doi: 10.1159/000058851
Doolan, D. L., Coppel, R. L. and Waters, A. P. (2001). Foreword--MBP thematic issue on genomics. Molecular and Biochemical Parasitology, 118 (2), 127-8. doi: 10.1016/s0166-6851(01)00389-9
Witney, Adam A., Doolan, Denise L., Anthony, Robert M., Weiss, Walter R., Hoffman, Stephen L. and Carucci, Daniel J. (2001). Determining liver stage parasite burden by real time quantitative PCR as a method for evaluating pre-erythrocytic malaria vaccine efficacy. Molecular and Biochemical Parasitology, 118 (2), 233-245. doi: 10.1016/S0166-6851(01)00372-3
Brice, G. T., Graber, N. L., Hoffman, S. L. and Doolan, D. L. (2001). Expression of the chemokine MIG is a sensitive and predictive marker for antigen-specific, genetically restricted IFN-γ production and IFN-γ-secreting cells. Journal of Immunological Methods, 257 (1-2), 55-69. doi: 10.1016/s0022-1759(01)00446-x
Wang, Ruobing, Epstein, Judith, Baraceros, Fe Maria, Gorak, Edward J., Charoenvit, Yupin, Carucci, Daniel J., Hedstrom, Richard C., Rahardjo, Nancy, Gay, Tanya, Hobart, Peter, Stout, Rick, Jones, Trevor R., Richie, Thomas L., Parker, Suezanne E., Doolan, Denise L., Norman, Jon and Hoffman, Stephen L. (2001). Induction of CD4+ T cell-dependent CD8+ type 1 responses in humans by a malaria DNA vaccine. Proceedings of the National Academy of Sciences of the United States of America, 98 (19), 10817-10822. doi: 10.1073/pnas.181123498
Doolan, Denise L and Hoffman, Stephen L (2001). DNA-based vaccines against malaria: Status and promise of the Multi-Stage Malaria DNA Vaccine Operation. International Journal for Parasitology, 31 (8), 753-762. doi: 10.1016/S0020-7519(01)00184-9
Gramzinski, R. A., Doolan, D. L., Sedegah, M., Davis, H. L., Krieg, A. M. and Hoffman, S. L. (2001). Interleukin-12- and gamma interferon-dependent protection against malaria conferred by CpG oligodeoxynucleotide in mice. Infection and Immunity, 69 (3), 1643-1649. doi: 10.1128/IAI.69.3.1643-1649.2001
Hoffman, Stephen L. and Doolan, Denise L. (2000). Malaria vaccines-targeting infected hepatocytes. Nature Medicine, 6 (11), 1218-1219. doi: 10.1038/81315
Ravichandran, M., Doolan, D. L., Cox-Singh, J., Hoffman, S. L. and Singh, B. (2000). HLA degenerate T-cell epitopes from Plasmodium falciparum liver stage-specific antigen 1 (LSA-1) are highly conserved in isolates from geographically distinct areas. Parasite Immunology, 22 (9), 469-473. doi: 10.1046/j.1365-3024.2000.00324.x
Doolan, Denise L. and Hoffman, Stephen L. (2000). The complexity of protective immunity against liver-stage malaria. Journal of Immunology, 165 (3), 1453-1462. doi: 10.4049/jimmunol.165.3.1453
Doolan, Denise L., Southwood, Scott, Chesnut, Robert, Appella, Ettore, Gomez, Eduardo, Richards, Allen, Higashimoto, Yuichiro I., Maewal, Ajesh, Sidney, John, Gramzinski, Robert A., Mason, Carl, Koech, Davy, Hoffman, Stephen L. and Sette, Alessandro (2000). HLA-DR-promiscuous T cell epitopes frown Plasmodium falciparum pre- erythrocytic-stage antigens restricted by multiple HLA class II alleles. Journal of Immunology, 165 (2), 1123-1137. doi: 10.4049/jimmunol.165.2.1123
Le, T. P., Coonan, K. M., Hedstrom, R. C., Charoenvit, Y., Sedegah, M., Epstein, J. E., Kumar, S., Wang, R., Doolan, D. L., Maguire, J. D., Parker, S. E., Hobart, P., Norman, J. and Hoffman, S. L. (2000). Safety, tolerability and humoral immune responses after intramuscular administration of a malaria DNA vaccine to healthy adult volunteers. Vaccine, 18 (18), 1893-1901. doi: 10.1016/s0264-410x(99)00407-7
Hoffman, S. L. and Doolan, D. L. (2000). Can malaria DNA vaccines on their own be as immunogenic and protective as prime-boost approaches to immunization?. Developments in biologicals, 104, 121-132.
Doolan, Denise L. and Hoffman, Stephen L. (1999). IL-12 and NK cells are required for antigen-specific adaptive immunity against malaria initiated by CD8+ T cells in the Plasmodium yoelii model. Journal of Immunology, 163 (2), 884-892.
Good, Michael F. and Doolan, Denise L. (1999). Immune effector mechanisms in malaria. Current Opinion in Immunology, 11 (4), 412-419. doi: 10.1016/S0952-7915(99)80069-7
Charoenvit, Yupin, Majam, Victoria Fallarme, Corradin, Giampietro, Sacci Jr., John B., Wang, Ruobing, Doolan, Denise L., Jones, Trevor R., Abot, Esteban, Patarroyo, Manuel E., Guzman, Fanny and Hoffman, Stephen L. (1999). CD4+ T-cell- and gamma interferon-dependent protection against murine malaria by immunization with linear synthetic peptides from a Plasmodium yoelii 17-kilodalton hepatocyte erythrocyte protein. Infection and Immunity, 67 (11), 5604-5614. doi: 10.1128/iai.67.11.5604-5614.1999
Wang, R, Doolan, D L, Le, T P, Hedstrom, R C, Coonan, K M, Charoenvit, Y, Jones, T R, Hobart, P, Margalith, M, Ng, J, Weiss, W R, Sedegah, M, de Taisne, C, Norman, J A and Hoffman, S L (1998). Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine. Science (New York, N.Y.), 282 (5388), 476-80. doi: 10.1126/science.282.5388.476
Wang, Ruobing, Doolan, Denise L., Charoenvit, Yupin, Hedstrom, Richard C., Gardner, Malcolm J., Hobart, Peter, Tine, John, Sedegah, Martha, Fallarme, Victoria, Sacci Jr., John B., Kaur, Manjit, Klinman, Dennis M., Hoffman, Stephen L. and Weiss, Walter R. (1998). Simultaneous induction of multiple antigen-specific cytotoxic T lymphocytes in nonhuman primates by immunization with a mixture of four Plasmodium falciparum DNA plasmids. Infection and Immunity, 66 (9), 4193-4202. doi: 10.1128/.66.9.4193-4202.1998
Hedstrom, R. C., Doolan, D. L., Wang, R., Kumar, A., Sacci Jr., J. B., Gardner, M. J., Aguiar, J. C., Charoenvit, Y., Sedegah, M., Tine, J. A., Margalith, M., Hobart, P. and Hoffman, S. L. (1998). In vitro expression and in vivo immunogenicity of Plasmodium falciparum pre-erythrocytic stage DNA vaccines. International journal of molecular medicine, 2 (1), 29-38. doi: 10.3892/ijmm.2.1.29
Doolan, D. L., Hedstrom, R. C., Gardner, M. J., Sedegah, M., Wang, H., Gramzinski, R. A., Maroatith, M., Hobart, P. and Hoffman, S. L. (1997). DNA vaccination as an approach to malaria control: Current status and strategies. Current Topics in Microbiology and Immunology, 226, 37-56.
Hedstrom, Richard C., Doolan, Denise L., Wang, Ruobing, Gardner, Malcolm J., Kumar, Anita, Sedegah, Martha, Gramzinski, Robert A., Sacci Jr., John B., Charoenvit, Yupin, Weiss, Walter R., Margalith, Michal, Norman, Jon A., Hobart, Peter and Hoffman, Stephen L. (1997). The development of a multivalent DNA vaccine for malaria. Springer Seminars in Immunopathology, 19 (2), 147-159. doi: 10.1007/BF00870265
Doolan, Denise L., Hedstrom, Richard C., Wang, Ruobing, Sedegah, Martha, Scheller, Libia F., Hobart, Peter, Norman, Jon A. and Hoffman, Stephen L. (1997). DNA vaccines for malaria: The past, the present, and the future. Indian Journal of Medical Research, 106 (AUG.), 109-119.
Doolan, D. L. and Hoffman, S. L. (1997). Multi-gene vaccination against malaria: A multistage, multi-immune response approach. Parasitology Today, 13 (5), 171-178. doi: 10.1016/s0169-4758(97)01040-5
Hoffman, Stephen L., Doolan, Denise L., Sedegah, Martha, Wang, Ruobing, Scheller, Libia F., Kumar, Anita, Weiss, Walter R., Le, Thong P., Klinman, Dennis M., Hobart, Peter, Norman, Jon A. and Hedstrom, Richard C. (1997). Toward clinical trials of DNA vaccines against malaria. Immunology and Cell Biology, 75 (4), 376-381. doi: 10.1038/icb.1997.59
Doolan, Denise L., Hoffman, Stephen L., Southwood, Scott, Wentworth, Peggy A., Sidney, John, Chesnut, Robert W., Keogh, Elissa, Appella, Ettore, Nutman, Thomas B., Lal, Altaf, Gordon, Daniel M., Oloo, Aggrey and Sette, Alessandro (1997). Degenerate cytotoxic T cell epitopes from P. falciparum restricted by multiple HLA-A and HLA-B supertype alleles. Immunity, 7 (1), 97-112. doi: 10.1016/S1074-7613(00)80513-0
Doolan, Denise L. and Hoffman, Stephen L. (1997). Pre-erythrocytic-stage immune effector mechanisms in plasmodium spp. infections. Philosophical Transactions of the Royal Society B: Biological Sciences, 352 (1359), 1361-1367. doi: 10.1098/rstb.1997.0121
Doolan, Denise L., Wizel, Benjamin and Hoffman, Stephen L. (1996). Class I HLA-restricted cytotoxic T lymphocyte responses against malaria-elucidation on the basis of HLA peptide binding motifs. Immunologic Research, 15 (4), 280-305. doi: 10.1007/BF02935313
Doolan, Denise L., Sedegah, Martha, Hedstrom, Richard C., Aguiar, Joao C. and Hoffman, Stephen L. (1996). DNA vaccination against malaria. Advanced Drug Delivery Reviews, 21 (1), 49-61. doi: 10.1016/0169-409X(96)00018-X
Doolan, D. L., Hedstrom, R. C., Rogers, W. O., Charoenvit, Y., Rogers, M., de la Vega, P. and Hoffman, S. L. (1996). Identification and characterization of the protective hepatocyte erythrocyte protein 17 kDa gene of Plasmodium yoelii, homolog of Plasmodium falciparum exported protein 1. The Journal of Biological Chemistry, 271 (30), 17861-17868. doi: 10.1074/jbc.271.30.17861
Doolan, D. L., Sedegah, M., Hedstrom, R. C., Hobart, P., Charoenvit, Y. and Hoffman, S. L. (1996). Circumventing genetic restriction of protection against malaria with multigene DNA immunization: CD8+ cell-, interferon gamma-, and nitric oxide-dependent immunity. The Journal of Experimental Medicine, 183 (4), 1739-1746. doi: 10.1084/jem.183.4.1739
Gardner, Malcolm J., Doolan, Denise L., Hedstrom, Richard C., Wang, Ruobing, Sedegah, Martha, Gramzinski, Robert A., Aguiar, Joao C., Wang, Helen, Margalith, Michal, Hobart, Peter and Hoffman, Stephen L. (1996). DNA vaccines against malaria: Immunogenicity and protection in a rodent model. Journal of Pharmaceutical Sciences, 85 (12), 1294-1300. doi: 10.1021/js960147h
HOFFMAN, S. L., DOOLAN, D. L., SEDEGAH, M., GRAMZINSKI, R., WANG, H., GOWDA, K., HOBART, P., MARGALITH, M., NORMAN, J. and HEDSTROM, R. C. (1995). Nucleic Acid Malaria Vaccines: Current Status and Potential. Annals of the New York Academy of Sciences, 772 (1), 88-94. doi: 10.1111/j.1749-6632.1995.tb44734.x
Argaet, V P, Schmidt, C W, Burrows, S R, Silins, S L, Kurilla, M G, Doolan, D L, Suhrbier, A, Moss, D J, Kieff, E, Sculley, T B and Misko, I S (1994). Dominant selection of an invariant T cell antigen receptor in response to persistent infection by Epstein-Barr virus. The Journal of Experimental Medicine, 180 (6), 2335-2340. doi: 10.1084/jem.180.6.2335
Doolan, D. L., Beck, H. P. and Good, M. F. (1994). Evidence for limited activation of distinct CD4+ T cell subsets in response to the Plasmodium falciparum circumsporozoite protein in Papua New Guinea. Parasite Immunology, 16 (3), 129-136. doi: 10.1111/j.1365-3024.1994.tb00332.x
Doolan, D. L., Khamboonruang, C., Beck, H. P., Houghten, R. A. and Good, M. F. (1993). Cytotoxic T lymphocyte (CTL) low-responsiveness to the Plasmodium falciparum circumsporozoite protein in naturally-exposed endemic populations: analysis of human CTL response to most known variants. International Immunology, 5 (1), 37-46. doi: 10.1093/intimm/5.1.37
Doolan, D. L. and Good, M. F. (1993). Developing a malaria sporozoite vaccine. Today's Life Science, 5 (6), 18-27.
Doolan, D. L., Saul, A. J. and Good, M. F. (1992). Geographically restricted heterogeneity of the Plasmodium falciparum circumsporozoite protein: relevance for vaccine development. Infection and Immunity, 60 (2), 675-682. doi: 10.1128/iai.60.2.675-682.1992
Doolan, D. L. and Good, M. F. (1992). Plasmodium falciparum CS protein--prime malaria vaccine candidate: definition of the human CTL domain and analysis of its variation. Memorias do Instituto Oswaldo Cruz, 87 Suppl 3, 241-247. doi: 10.1590/s0074-02761992000700040
Doolan, D. L., Houghten, R. A. and Good, M. F. (1991). Location of human cytotoxic T cell epitopes within a polymorphic domain of the Plasmodium falciparum circumsporozoite protein. International Immunology, 3 (6), 511-516. doi: 10.1093/intimm/3.6.511
Walker, P. J., Byrne, K. A., Cybinski, D. H., Doolan, D. L. and Wang, Y. H. (1991). Proteins of bovine ephemeral fever virus. Journal of General Virology, 72 ( Pt 1) (1), 67-74. doi: 10.1099/0022-1317-72-1-67
Doolan, D. L., Houghten, R. A. and Good, M. F. (1991). Assessment of human cytotoxic T cell activity using synthetic peptides: potential for field application. Peptide Research, 4 (3), 125-131.
Doolan, D. L. and Ward, L. C. (1987). Amino acid supply and protein metabolism in Ehrlich ascites tumour cells. 2 Incorporation of 14C-tyrosine. Cytobios, 50 (204), 49-61.
Doolan, DL and Ward, LC (1987). Amino-Acid Supply and Protein-Metabolism in Ehrlich Ascites Tumor-Cells .1. Identification of Limiting Amino-Acids. Cytobios, 51 (204), 7-23.
Doolan, D. L. and Ward, L. C. (1987). Amino acid supply and protein metabolism in Ehrlich ascites tumour cells. 2. Incorporation of 14C-tyrosine. Cytobios, 51 (204), 49-61.
Doolan, DL and Ward, LC (1987). Amino-Acid Supply and Protein-Metabolism in Ehrlich Ascites Tumor-Cells .2. Incorporation of C-14 Tyrosine. Cytobios, 51 (204), 49-61.
Conference Papers
Proietti, Carla, Krause, Lutz, Roddick, Joanne, Trieu, Angela and Doolan, Denise L. (2012). Dissecting T cell or antibody immunodominance in a complex host-pathogen system. Challenges in Malaria Research, Basel, Switzerland, 10-12 October 2012. London, United Kingdom: BioMed Central. doi: 10.1186/1475-2875-11-s1-o23
Cardoso, F. C., Groves, P., Roddick, J. and Doolan, D. L. (2010). Proteome-wide screening of complex pathogens to identify antigens targeted by T-cell mediated immune responses. XII International Conference for Parasitology, Melbourme, Australia, 15-20 August 2010.
Cardoso, F. C., Trieu, A., Groves, P. and Doolan, D. L. (2010). Proteome-wide screening of antigens targeted by cell mediated immune responses. 14th International Congress of Immunology, Kobe, Japan, 22-27 August 2010.
Driguez, Patrick, Ellis, Magda, McWilliarn, Hamish, Trieu, Angela, Gaze, Soraya, Jones, Malcolm K., Gobert, Geoff, Loukas, Alex, Doolan, Denise L., Felgner, Philip L. and McManus, Donald P. (2010). Development and immunoscreening of an immunomics protein microarray to investigate schistosomiasis. 59th Annual Meeting of the American Society of Tropical Medicine and Hygiene (ASTMH), Atlanta, GA, United States, 3-7 November, 2010. Deerfield, IL, United States : American Society of Tropical Medicine and Hygiene .
Engers, Howard, Kieny, Marie Paule, Malhotra, Pawan, Pink, J. Richard, Davies, Gwyn, Kensil, Charlotte Read, Jeannin, Pascale, Aubry, Jean-Pierre, Goetsch, Liliane, Delneste, Yves, Bonnefoy, Jean-Yves, Revets, Hilde, De Baetselier, Patrick, Steward, Michael, Fritchley, Sarah J., Bright, Jeremy R., Oldroyd, Rodney G., Affleck, Louise J., Ross, Ted M., Holder, Anthony A., Smith, Richard A.G., Kenney, Richard, Glenn, Gregory, Czerkinsky, Cecil, Del Giudice, Giuseppe, Zurbriggen, Rinaldo, Glück, Reinhard, Drane, Debbie, Pearse, Martin ... Sedegah, M. (2003). Third meeting on Novel Adjuvants Currently in or Close to Clinical Testing World Health Organization - Organisation Mondiale de la Santé, Fondation Mérieux, Annecy, France, 7-9 January 2002. Elsevier BV. doi: 10.1016/S0264-410X(03)00164-6
Hoffman, Stephen L., Doolan, Denise L., Sedegah, Martha, Aguiar, Joao C., Wang, Ruobing, Malik, Anita, Gramzinski, Robert A., Weiss, Walter R., Hobart, Peter, Norman, Jon A., Margalith, Michal and Hedstrom, Richard C. (1997). Strategy for development of a pre-erythrocytic Plasmodium falciparum DNA vaccine for human use. doi: 10.1016/S0264-410X(96)00273-3
Gramzinski, Robert A., Maris, Dorina C., Doolan, Denise, Charoenvit, Yupin, Obaldia, Nicanor, Rossan, Richard, Sedegah, Martha, Wang, Ruobing, Hobart, Peter, Margalith, Michal and Hoffman, Stephen (1997). Malaria DNA vaccines in Aotus monkeys. doi: 10.1016/S0264-410X(96)00270-8
Murphy, G. M., St. George, T. D., Guerrini, V., Collins, R. G., Broadmeadow, A. C., Uren, M. F. and Doolan, D. L. (1988). Trace element and macro electrolyte behaviour during inflammatory diseases in cattle and sheep. Sixth International Symposium on Trace Elements in Man and Animals, Pacific Grove, CA, United States, 31 May-5 June 1987. New York, NY, United States: Plenum Press.