Dr Elena-Laura Budusan
Postdoctoral Research Fellow
Institute for Molecular Bioscience
Book Chapter
Senescall, Victor, Budusan, Elena, Knezic, Adriana, Waqar, Maleeha, Butcher, Neville, Khan, Nemat, McCarthy, Claudia, Widopp, Robert, Karatt-Vellat, Aneesh and Rash, Lachlan D. (2024). Targeting acid-sensing ion channels in disease. Ion channels as targets in drug discovery. (pp. 303-355) edited by Gary Stephens and Edward Stevens. Cham, Switzerland: Springer. doi: 10.1007/978-3-031-52197-3_10
Journal Articles
Cristofori-Armstrong, Ben, Budusan, Elena, Smith, Jennifer J., Reynaud, Steve, Voll, Kerstin, Chassagnon, Irène R., Durek, Thomas and Rash, Lachlan D. (2024). Revealing molecular determinants governing mambalgin-3 pharmacology at acid-sensing ion channel 1 variants. Cellular and Molecular Life Sciences, 81 (1) 266, 266. doi: 10.1007/s00018-024-05276-2
Budusan, Elena, Payne, Colton D., Gonzalez, Tye I., Obergrussberger, Alison, Becker, Nadine, Clark, Richard J., Rosengren, K. Johan, Rash, Lachlan D. and Cristofori-Armstrong, Ben (2024). The funnel-web spider venom derived single knot peptide Hc3a modulates acid-sensing ion channel 1a desensitisation. Biochemical Pharmacology, 228 116175, 1-12. doi: 10.1016/j.bcp.2024.116175
Knezic, Adriana, Budusan, Elena, Saez, Natalie J., Broughton, Brad R. S., Rash, Lachlan D., King, Glenn F., Widdop, Robert E. and McCarthy, Claudia A. (2024). Hi1a improves sensorimotor deficit following endothelin-1-induced stroke in rats but does not improve functional outcomes following filament-induced stroke in mice. ACS Pharmacology and Translational Science, 7 (4), 1043-1054. doi: 10.1021/acsptsci.3c00328
Tran, Hue N. T., Budusan, Elena, Saez, Natalie J., Norman, Alexander, Tucker, Isaac J., King, Glenn F., Payne, Richard J., Rash, Lachlan D., Vetter, Irina and Schroeder, Christina I. (2023). Evaluation of peptide ligation strategies for the synthesis of the bivalent acid-sensing ion channel inhibitor Hi1a. Organic Letters, 25 (24), 4439-4444. doi: 10.1021/acs.orglett.3c01346
Duggan, Nisharnthi M., Saez, Natalie J., Clayton, Daniel, Budusan, Elena, Watson, Emma E., Tucker, Isaac J., Rash, Lachlan D., King, Glenn F. and Payne, Richard J. (2021). Total synthesis of the spider-venom peptide Hi1a. Organic Letters, 23 (21) acs.orglett.1c03112, 8375-8379. doi: 10.1021/acs.orglett.1c03112
Cristofori-Armstrong, Ben, Budusan, Elena and Rash, Lachlan D. (2021). Mambalgin-3 potentiates human acid-sensing ion channel 1b under mild to moderate acidosis: implications as an analgesic lead. Proceedings of the National Academy of Sciences, 118 (8) e2021581118, 1-3. doi: 10.1073/pnas.2021581118
Michlits, Georg, Hubmann, Maria, Wu, Szu-Hsien, Vainorius, Gintautas, Budusan, Elena, Zhuk, Sergei, Burkard, Thomas R., Novatchkova, Maria, Aichinger, Martin, Lu, Yiqing, Reece-Hoyes, John, Nitsch, Roberto, Schramek, Daniel, Hoepfner, Dominic and Elling, Ulrich (2017). CRISPR-UMI : single-cell lineage tracing of pooled CRISPR-Cas9 screens. Nature Methods, 14 (12), 1191-1201. doi: 10.1038/nmeth.4466
Conference Papers
Tucker, Isaac, King, Glenn, Saez, Natalie, Deplazes, Evelyne, Rash, Lachlan, Cristofori-Armstrong, Ben and Budusan, Elena (2024). In-silico application of structure prediction to peptide mechanism of action. 37th European Peptide Symposium 14th International Peptide Symposium, Florence, Italy, 25-29 August 2024. Oxford, United Kingdom: John Wiley & Sons.
Sirtori, Elena, Rolland, Jean-Francois, Budusan, Elena L., Rotordam, Giustina M., Goetze, Tom A., Becker, Nadine, Obergrussberger, Alison, Strassmaier, Timothy, Bruggemann, Andrea, George, Michael and Fertig, Niels (2023). Pharmacology of P2X3 and P2X2/3 receptors: an automated patch clamp study. Biophysical Society 67th Annual Meeting, San Diego, CA USA, 18-22 February 2023. St. Louis, MO USA: Cell Press. doi: 10.1016/j.bpj.2022.11.1450