Mr Jared Coombs
PhD Student & Casual Senior Research Assistant
Institute for Molecular Bioscience
Publications
Journal Articles
Coombs, Jared R, Burgener, Sabrina S and Schroder, Kate (2026). Clinical inflammasome biomarkers: Progress and prospects. Journal of Molecular Biology 169941, 169941. doi: 10.1016/j.jmb.2026.169941
Pizzuto, Malvina, Monteleone, Mercedes, Burgener, Sabrina Sofia, Began, Jakub, Kurera, Melan, Chia, Jing Rong, Frampton, Emmanuelle, Crawford, Joanna, Oliveira, Monalisa, Kenney, Kirsten M., Coombs, Jared R., Yamamoto, Masahiro, Man, Si Ming, Broz, Petr, Pelegrin, Pablo and Schroder, Kate (2025). Cardiolipin inhibits the non-canonical inflammasome by preventing LPS binding to caspase-4/11. The EMBO Journal, 44 (16), 4419-4442. doi: 10.1038/s44318-025-00507-z
Coombs, Jared R., Burgener, Sabrina S. and Schroder, Kate (2025). Spectosis: dying for a complement. Immunity, 58 (6), 1372-1374. doi: 10.1016/j.immuni.2025.05.017
Holley, Caroline L., Monteleone, Mercedes, Fisch, Daniel, Libert, Alexandre E. S., Ju, Robert J., Choi, Joon H., Condon, Nicholas D., Emming, Stefan, Crawford, Joanna, Lawrence, Grace M. E. P., Coombs, Jared R., Lefevre, James G., Bajracharya, Rinie, Lahoud, Mireille H., Yap, Alpha S., Hamilton, Nicholas, Stehbens, Samantha J., Kagan, Jonathan C., Ariotti, Nicholas, Burgener, Sabrina S. and Schroder, Kate (2024). Pyroptotic cell corpses are crowned with F-actin-rich filopodia that engage CLEC9A signaling in incoming dendritic cells. Nature Immunology, 26 (1) eaas8995, 1-35. doi: 10.1038/s41590-024-02024-3
Pizzuto, Malvina, Monteleone, Mercedes, Burgener, Sabrina Sofia, Began, Jakub, Kurera, Melan, Chia, Jing Rong, Frampton, Emmanuelle, Crawford, Joanna, Oliveira, Monalisa, Kenney, Kirsten M., Coombs, Jared R., Yamamoto, Masahiro, Man, Si Ming, Broz, Petr, Pelegrin, Pablo and Schroder, Kate (2024). Cardiolipin Inhibits the Noncanonical Inflammasome by Preventing LPS Binding to Caspase 4/11 to Mitigate Endotoxemia in Vivo. BioRxiv, 1-24. doi: 10.1101/2024.10.14.618051
Coombs, Jared R., Zamoshnikova, Alina, Holley, Caroline L., Maddugoda, Madhavi P., Teo, Daniel Eng Thiam, Chauvin, Camille, Poulin, Lionel F, Vitak, Nazarii, Ross, Connie M., Mellacheruvu, Manasa, Coll, Rebecca C., Heinz, Leonhard X., Burgener, Sabrina S., Emming, Stefan, Chamaillard, Mathias, Boucher, Dave and Schroder, Kate (2024). NLRP12 interacts with NLRP3 to block the activation of the human NLRP3 inflammasome. Science Signaling, 17 (820) abg8145, eabg8145. doi: 10.1126/scisignal.abg8145