Mr Xiaosa Wu
Higher degree by research (PhD) student
Institute for Molecular Bioscience
+61 7 334 62023
Journal Articles
Wu, Xiaosa, Gupta, Kanchan and Swartz, Kenton J. (2022). Mutations within the selectivity filter reveal that Kv1 channels have distinct propensities to slow inactivate. Journal of General Physiology, 154 (11). doi: 10.1085/jgp.202213222
Yousuf, Arsalan, Wu, Xiaosa, Bony, Anuja R., Sadeghi, Mahsa, Huang, Yen-Hua, Craik, David J. and Adams, David J. (2022). ɑO-Conotoxin GeXIVA isomers modulate N-type calcium (CaV2.2) channels and inwardly-rectifying potassium (GIRK) channels via GABAB receptor activation. Journal of Neurochemistry, 160 (2), 154-171. doi: 10.1111/jnc.15535
Wu, Xiaosa, Craik, David J. and Kaas, Quentin (2021). Interactions of globular and ribbon [γ4E]GID with α4β2 neuronal nicotinic acetylcholine receptor. Marine Drugs, 19 (9) 482. doi: 10.3390/md19090482
El Hamdaoui, Yamina, Wu, Xiaosa, Clark, Richard J., Giribaldi, Julien, Anangi, Raveendra, Craik, David J., King, Glenn F., Dutertre, Sebastien, Kaas, Quentin, Herzig, Volker and Nicke, Annette (2019). Periplasmic expression of 4/7 alpha-conotoxin TxIA analogs in E. coli favors ribbon isomer formation suggestion of a binding mode at the α7 nAChR. Frontiers in Pharmacology, 10 (MAY) 577, 577. doi: 10.3389/fphar.2019.00577
Wu, Xiaosa, Tae, Han-Shen, Huang, Yen-Hua, Adams, David J., Craik, David J. and Kaas, Quentin (2018). Stoichiometry dependent inhibition of rat α3β4 nicotinic acetylcholine receptor by the ribbon isomer of α-conotoxin AuIB. Biochemical Pharmacology, 155, 288-297. doi: 10.1016/j.bcp.2018.07.007
Wu, Xiaosa, Huang, Yen-Hua, Kaas, Quentin, Harvey, Peta J., Wang, Conan K., Tae, Han-Shen, Adams, David J. and Craik, David J. (2017). Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer. Journal of Biological Chemistry, 292 (41), 17101-17112. doi: 10.1074/jbc.M117.808386
Wu, Xiaosa, Huang, Yen-Hua, Kaas, Quentin and Craik, David J. (2016). Cyclisation of disulfide-rich conotoxins in drug design applications. European Journal of Organic Chemistry, 2016 (21), 3462-3472. doi: 10.1002/ejoc.201600402
Wu, Xiaosa, Huang, Yen-Hua, Kaas, Quentin and Craik, David J. (2016). Front Cover: Cyclisation of Disulfide-Rich Conotoxins in Drug Design Applications (Eur. J. Org. Chem. 21/2016). European Journal of Organic Chemistry, 2016 (21), 3457-3457. doi: 10.1002/ejoc.201670211
Wu, Yong, Wu, Xiaosa, Yu, Jinpeng, Zhu, Xiaopeng, Zhangsun, Dongting and Luo, Sulan (2014). Influence of disulfide connectivity on structure and bioactivity of alpha-conotoxin TxIA. Molecules, 19 (1), 966-979. doi: 10.3390/molecules19010966
Wu, Xiaosa, Wu, Yong, Zhu, Furong, Yang, Qiuyuan, Wu, Qianqian, Zhangsun, Dongting and Luo, Sulan (2013). Optimal cleavage and oxidative folding of alpha-conotoxin TxIB as a therapeutic candidate pPeptide. Marine Drugs, 11 (9), 3537-3553. doi: 10.3390/md11093537
Gao, Bingmiao, Zhangsun, Dongting, Hu, Yuanyan, Wu, Yong, Sheng, Lizi, Fang, Licong, Wu, Xiaosa, Yu, Jinpeng and Luo, Sulan (2013). Expression and secretion of functional recombinant mu O-conotoxin MrVIB-His-tag in Escherichia coli. Toxicon, 72, 81-89. doi: 10.1016/j.toxicon.2013.06.012
Thesis
Wu, Xiaosa (2019). Engineering the ribbon isomer of α-conotoxins in the drug design application. PhD Thesis, Institute for Molecular Bioscience, The University of Queensland. doi: 10.14264/uql.2019.537