Adjunct Professor Norelle Daly
Adjunct Professor
Institute for Molecular Bioscience
Book Chapters
Daly, Norelle L., Gruber, Christian W., Goransson, Ulf and Craik, David J. (2011). Cystine knot folding in cyclotides. Folding of disulfide proteins. (pp. 43-61) edited by Chang, RJY and Ventura, S. New York , NY, U.S.A.: Springer. doi: 10.1007/978-1-4419-7273-6
Rosengren, K. Johan, Daly, N. L. and Craik, D. J. (2009). NMR of peptide toxins. Annual reports on NMR Spectroscopy. (pp. 89-147) edited by Graham A. Webb. Oxford England U.K.: Academic Press Elsevier. doi: 10.1016/S0066-4103(09)06802-1
Daly, N. L. and Craik, D. J. (2009). Folding motifs of cystine-rich peptides. Oxidative folding of peptides and proteins. (pp. 318-344) edited by Johannes Buchner and Luis Moroder. Cambridge, UK: Royal Society of Chemistry.
Journal Articles
Khudhair, Zainab, Alhallaf, Rafid, Eichenberger, Ramon M., Whan, Jen, Kupz, Andreas, Field, Matt, Krause, Lutz, Wilson, David T., Daly, Norelle L., Giacomin, Paul, Sotillo, Javier and Loukas, Alex (2021). Gastrointestinal helminth infection improves insulin sensitivity, decreases systemic inflammation, and alters the composition of gut microbiota in distinct mouse models of Type 2 diabetes. Frontiers in Endocrinology, 11 606530, 1-16. doi: 10.3389/fendo.2020.606530
Malik, Uru, Chan, Lai Yue, Cai, Minying, Hruby, Victor J., Kaas, Quentin, Daly, Norelle L. and Craik, David J. (2020). Development of novel frog‐skin peptide scaffolds with selectivity towards melanocortin receptor subtypes. Peptide Science, 113 (4) e24209. doi: 10.1002/pep2.24209
Durek, Thomas, Cromm, Philipp M., White, Andrew M., Schroeder, Christina I., Kaas, Quentin, Weidmann, Joachim, Ahmad Fuaad, Abdullah, Cheneval, Olivier, Harvey, Peta J., Daly, Norelle L., Zhou, Yang, Dellsén, Anita, Österlund, Torben, Larsson, Niklas, Knerr, Laurent, Bauer, Udo, Kessler, Horst, Cai, Minying, Hruby, Victor J., Plowright, Alleyn T. and Craik, David J. (2018). Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1. Journal of Medicinal Chemistry, 61 (8), 3674-3684. doi: 10.1021/acs.jmedchem.8b00170
Daly, Norelle L., Gunasekera, Sunithi, Clark, Richard J., Lin, Feng, Wade, John D., Anderson, Marilyn and Craik, David J. (2016). The N-terminal pro-domain of the kalata B1 cyclotide precursor is intrinsically unstructured. Biopolymers, 106 (6), 825-833. doi: 10.1002/bip.22977
Harris, Karen S., Durek, Thomas, Kaas, Quentin, Poth, Aaron G., Gilding, Edward K., Conlan, Brendon F., Saska, Ivana, Daly, Norelle L., Van Der Weerden, Nicole L., Craik, David J. and Anderson, Marilyn A. (2015). Efficient backbone cyclization of linear peptides by a recombinant asparaginyl endopeptidase. Nature Communications, 6 (10199) 10199, 10199. doi: 10.1038/ncomms10199
Akcan, Muharrem, Clark, Richard J., Daly, Norelle L., Conibear, Anne C., de Faoite, Andrew, Heghinian, Mari D., Sahil, Talwar, Adams, David J., Mari, Frank and Craik, David J. (2015). Transforming conotoxins into cyclotides: backbone cyclization of P-superfamily conotoxins. Peptide Science, 104 (6), 682-692. doi: 10.1002/bip.22699
Huang, Yen-Hua, Henriques, Sonia T., Wang, Conan K., Thorstholm, Louise, Daly, Norelle L., Kaas, Quentin and Craik, David J. (2015). Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold. Scientific Reports, 5 (1) 12974, 1-15. doi: 10.1038/srep12974
Malik, U., Silva, O. N., Fensterseifer, I. C. M., Chan, A., Clark, R. J., Franco, O. L., Daly, N. L. and Craik, D. J. (2015). In vivo efficacy of anuran rypsin inhibitory peptides against Staphylococcal Skin infection and the impact of peptide cyclization. Antimicrobial Agents and Chemotherapy, 59 (4), 2113-2121. doi: 10.1128/AAC.04324-14
Haugaard-Kedstrom, Linda, Hossain, Mohammed Akhter, Daly, Norelle L., Bathgate, Ross A. D., Rinderknecht, Ernst, Wade, John D., Craik, David J. and Rosengren, Karl Johan (2015). Solution structure, aggregation behavior, and flexibility of human relaxin-2. ACS Chemical Biology, 10 (3), 891-900. doi: 10.1021/cb500918v
Vink, Simone, Daly, Norelle L., Steen, Natalie, Craik, David J. and Alewood, Paul F. (2014). Holocyclotoxin-1, a cystine knot toxin from Ixodes holocyclus. Toxicon, 90 (1), 308-317. doi: 10.1016/j.toxicon.2014.08.068
Berecki, G., Daly, N. L., Huang, Y. H., Vink, S., Craik, D. J., Alewood, P. F. and Adams, D. J. (2014). Effects of arginine 10 to lysine substitution on omega-conotoxin CVIE and CVIF block of Ca(v)2.2 channels. British Journal of Pharmacology, 171 (13), 3313-3327. doi: 10.1111/bph.12686
Schroeder, Christina I., Swedberg, Joakim E., Withka, Jane M., Rosengren, K. Johan, Akcan, Muharrem, Clayton, Daniel J., Daly, Norelle L., Cheneval, Olivier, Borzilleri, Kris A., Griffor, Matt, Stock, Ingrid, Colless, Barbara, Walsh, Phillip, Sunderland, Phillip, Reyes, Allan, Dullea, Robert, Ammirati, Mark, Liu, Shenping, McClure, Kim F., Tu, Meihua, Bhattacharya, Samit K., Liras, Spiros, Price, David A. and Craik, David J. (2014). Design and synthesis of truncated EGF-A peptides that restore LDL-R recycling in the presence of PCSK9 in vitro. Chemistry and Biology, 21 (2), 284-294. doi: 10.1016/j.chembiol.2013.11.014
Gui, Junhong, Liu, Boyi, Cao, Guan, Lipchik, Andrew M., Perez, Minervo, Dekan, Zoltan, Mobli, Mehdi, Daly, Norelle L., Alewood, Paul F., Parker, Laurie L., King, Glenn F., Zhou, Yufeng, Jordt, Sven-Eric and Nitabach, Michael N. (2014). A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1–S4 gating domain. Current Biology, 24 (5), 473-483. doi: 10.1016/j.cub.2014.01.013
Lay, Fung T., Poon, Simon, McKenna, James A., Connelly, Angela A., Barbeta, Barbara L., McGinness, Bruce S., Fox, Jennifer L., Daly, Norelle L., Craik, David J., Heath, Robyn L. and Anderson, Marilyn A. (2014). The C-terminal propeptide of a plant defensin confers cytoprotective and subcellular targeting functions. BMC Plant Biology, 14 (1) 41, 41.1-41.13. doi: 10.1186/1471-2229-14-41
Jia, Xinying, Schulte, Leigh, Loukas, Alex, Pickering, Darren, Pearson, Mark, Mobli, Mehdi, Jones, Alun, Rosengren, Karl J., Daly, Norelle L., Gobert, Geoffrey N., Jones, Malcolm K., Craik, David J. and Mulvenna, Jason (2014). Solution structure, membrane interactions and protein binding partners of the tetraspanin Sm-TSP-2, a vaccine antigen from the human blood fluke Schistosoma mansoni. Journal of Biological Chemistry, 289 (10), 1-26. doi: 10.1074/jbc.M113.531558
Rosengren, K. Johan, Daly, Norelle L., Harvey, Peta J. and Craik, David J. (2013). The Self-Association of the Cyclotide Kalata B2 in Solution is Guided by Hydrophobic Interactions (vol 100, pg 453, 2013). Biopolymers, 102 (1), 136-136. doi: 10.1002/bip.22443
Daly, Norelle L., Thorstholm, Louise, Greenwood, Kathryn P., King, Gordon J., Rosengren, K. Johan, Heras, Begona, Martin, Jennifer L. and Craik, David J. (2013). Structural insights into the role of the cyclic backbone in a squash trypsin inhibitor. Journal of Biological Chemistry, 288 (50), 36141-36148. doi: 10.1074/jbc.M113.528240
Akcan, Muharrem, Stroud, Mark R., Hansen, Stacey J., Clark, Richard J., Daly, Norelle L., Craik, David J. and Olson, James M. (2013). Erratum: Chemical re-engineering of chlorotoxin improves bioconjugation properties for tumor imaging and targeted therapy (Journal of Medicinal Chemistry (2011) 54 (782-787) DOI: 10.1021/jm101018r). Journal of Medicinal Chemistry, 56 (23), 9807-9807. doi: 10.1021/jm4016119
Koehbach, Johannes, O'Brien, Margaret, Muttenthaler, Markus, Miazzo, Marion, Akcan, Muharrem, Elliott, Alysha G., Daly, Norelle L., Harvey, Peta J., Arrowsmith, Sarah, Gunasekera, Sunithi, Smith, Terry J., Wray, Susan, Göransson, Ulf, Dawson, Philip E., Craik, David J., Freissmuth, Michael and Gruber, Christian W. (2013). Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design. Proceedings of the National Academy of Sciences of the United States of America, 110 (52), 21183-21188. doi: 10.1073/pnas.1311183110
Brust, Andreas, Wang, Ching-I. A., Daly, Norelle L., Kennerly, Joe, Sadeghi, Mahsa, Christie, Macdonald J., Lewis, Richard J., Mobli, Mehdi and Alewood, Paul F. (2013). Vicinal disulfide constrained cyclic peptidomimetics: a turn mimetic scaffold targeting the norepinephrine transporter. Angewandte Chemie (International Edition), 52 (46), 12020-12023. doi: 10.1002/anie.201304660
He, Wen-Jun, Chan, Lai Yue, Clark, Richard J., Tang, Jun, Zeng, Guang-Zhi, Franco, Octavio L., Cantacessi, Cinzia, Craik, David J., Daly, Norelle L. and Tan, Ning-Hua (2013). Novel inhibitor cystine knot peptides from momordica charantia. PLoS ONE, 8 (10) e75334, e75334.1-e75334.10. doi: 10.1371/journal.pone.0075334
Hardy, Margaret C., Daly, Norelle L., Mobli, Mehdi, Morales, Rodrigo A. V. and King, Glenn F. (2013). Isolation of an orally active insecticidal toxin from the venom of an Australian tarantula. PLoS ONE, 8 (9), e73136.1-e73136.12. doi: 10.1371/journal.pone.0073136
Malagon, David, Botterill, Bonnie, Gray, Darren J., Lovas, Erica, Duke, Mary, Gray, Christian, Kopp, Steven R., Knott, Lyn M., McManus, Donald P., Daly, Norelle L., Mulvenna, Jason, Craik, David J. and Malcolm K Jones (2013). Anthelminthic activity of the cyclotides (kalata B1 and B2) against schistosome parasites. Biopolymers, 100 (5), 461-470. doi: 10.1002/bip.22229
Inserra, Marco C., Kompella, Shiva N., Vetter, Irina, Brust, Andreas, Daly, Norelle L., Cuny, Hartmut, Craik, David J., Alewood, Paul F., Adams, David J. and Lewis, Richard J. (2013). Isolation and characterization of alpha-conotoxin LsIA with potent activity at nicotinic acetylcholine receptors. Biochemical Pharmacology, 86 (6), 791-799. doi: 10.1016/j.bcp.2013.07.016
Rosengren, K. Johan, Daly, Norelle L., Harvey, Peta J. and Craik, David J. (2013). The self-association of the cyclotide kalata B2 in solution is guided by hydrophobic interactions. Peptide Science, Accepted Article (5), 1-16. doi: 10.1002/bip.22269
Quimbar, Pedro, Malik, Uru, Sommerhoff, Christian P., Kaas, Quentin, Chan, Lai Y., Huang, Yen-Hua, Grundhuber, Maresa, Dunse, Kerry, Craik, David J., Anderson, Marilyn A. and Daly, Norelle L. (2013). High-affinity cyclic peptide matriptase inhibitors. Journal of Biological Chemistry, 288 (19), 13885-13896. doi: 10.1074/jbc.M113.460030
Conibear, Anne C., Rosengren, K. Johan, Daly, Norelle L., Henriques, Sonia Troeira and Craik, David J. (2013). The cyclic cystine ladder in theta-defensins is important for structure and stability, but not antibacterial activity. Journal of Biological Chemistry, 288 (15), 10830-10840. doi: 10.1074/jbc.M113.451047
Chan, Lai Yue, Zhang, Veronica M., Huang, Yen-hua, Waters, Norman C., Bansal, Paramjit S., Craik, David J. and Daly, Norelle L. (2013). Cyclization of the antimicrobial peptide gomesin with native chemical ligation: influences on stability and bioactivity. Chembiochem, 14 (5), 617-624. doi: 10.1002/cbic.201300034
Hashempour, Hossein, Koehbach, Johannes, Daly, Norelle L., Ghassempour, Alireza and Gruber, Christian W. (2013). Characterizing circular peptides in mixtures: sequence fragment assembly of cyclotides from a violet plant by MALDI-TOF/TOF mass spectrometry. Amino Acids, 44 (2), 581-595. doi: 10.1007/s00726-012-1376-x
Chan, Lai Yue, He, Wenjun, Tan, Ninghua, Zeng, Guangzhi, Craik, David J. and Daly, Norelle L. (2013). A new family of cystine knot peptides from the seeds of Momordica cochinchinensis. Peptides, 39 (1), 29-35. doi: 10.1016/j.peptides.2012.09.018
Eliasen, Rasmus, Daly, Norelle L., Wulff, Birgitte S., Andresen, Thomas L., Conde-Frieboes, Kilian W. and Craik, David J. (2012). Design, Synthesis, Structural and Functional Characterization of Novel Melanocortin Agonists Based on the Cyclotide Kalata B1. Journal of Biological Chemistry, 287 (48), 40493-40501. doi: 10.1074/jbc.M112.395442
Hall, Kristopher, Lee, Tzong-Hsien, Daly, Norelle L., Craik, David J. and Aguilar, Marie-Isabel (2012). Gly6 of kalata B1 is critical for the selective binding to phosphatidylethanolamine membranes. BBA: Biomembranes, 1818 (9), 2354-2361. doi: 10.1016/j.bbamem.2012.04.007
Henriques, Sonia Troeira, Huang, Yen-Hua, Castanho, Miguel A. R. B., Bagatolli, Luis A., Sonza, Secondo, Tachedjan, Gilda, Daly, Norelle L. and Craik, David J. (2012). Phosphatidylethanolamine-binding is a conserved feature of cyclotide-membrane interactions. Journal of Biological Chemistry, 287 (40), 33629-33643. doi: 10.1074/jbc.M112.372011
Conibear, Anne, Daly, Norelle L. and Craik, David J. (2012). Quantification of small cyclic disulfide-rich peptides. Biopolymers, 98 (6), 518-524. doi: 10.1002/bip.22121
Mylne, Joshua S., Chan, Lai Yue, Chanson, Aurelie H., Daly, Norelle L., Schaefer, Hanno, Bailey, Timothy L., Nguyencong, Philip, Cascales, Laura and Craik, David J. (2012). Cyclic peptides arising by evolutionary parallelism via asparaginyl-endopeptidase–mediated biosynthesis. Plant Cell, 24 (7), 2765-2778. doi: 10.1105/tpc.112.099085
Clark, Richard J., Akcan, Muharrem, Kaas, Quentin, Daly, Norelle L. and Craik, David J. (2012). Cyclization of conotoxins to improve their biopharmaceutical properties. Toxicon, 59 (4), 446-455. doi: 10.1016/j.toxicon.2010.12.003
Carstens, Bodil B., Clark, Richard J., Daly, Norelle L., Harvey, Peta J., Kaas, Quentin and Craik, David J. (2012). Corrigendum: Engineering of Conotoxins for the Treatment of Pain (Current Pharmaceutical Design, (2011), 17, 38). Current Pharmaceutical Design, 18 (8) doi: 10.2174/138161212799315858
Franco, Aldo, Kompella, Shiva N., Akondi, Kalyana B., Melaun, Christian, Daly, Norelle L., Luetje, Charles W., Alewood, Paul F., Craik, David J., Adams. David J. and Mari, Frank (2012). RegIIA: An alpha 4/7-conotoxin from the venom of Conus regius that potently blocks alpha 3 beta 4 nAChRs. Biochemical Pharmacology, 83 (3), 419-426. doi: 10.1016/j.bcp.2011.11.006
Andersson, Hakan S., Figueredo, Sharel M., Haugaard-Kedstrom, Linda M., Bengtsson, Elina, Daly, Norelle L., Qu, Xiaoqing, Craik, David J., Ouellette, Andre J. and Rosengren, K. Johan (2012). The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance. Amino Acids, 43 (4), 1471-1483. doi: 10.1007/s00726-012-1220-3
Carstens, Bodil B., Clark, Richard J., Daly, Norelle L., Harvey, Peta J., Kaas, Quentin and Craik, David J. (2011). Engineering of conotoxins for the treatment of pain. Current Pharmaceutical Design, 17 (38), 4242-4253. doi: 10.2174/138161211798999401
Sando, Lillian, Henriques, Sonia Troeira, Foley, Fiona, Simonsen, Shane M., Daly, Norelle L., Hall, Kristopher N., Gustafson, Kirk R., Aguilar, Marie-Isabel and Craik, David J. (2011). A synthetic mirror image of kalata B1 reveals that cyclotide activity is independent of a protein receptor. ChemBioChem, 12 (16), 2456-2462. doi: 10.1002/cbic.201100450
Smith, Amanda B., Daly, Norelle L. and Craik, David J. (2011). Cyclotides: A patent review. Expert Opinion On Therapeutic Patents, 21 (11), 1657-1672. doi: 10.1517/13543776.2011.620606
Chan, Lai Y., Gunasekera, Sunithi, Henriques, Sonia T., Worth, Natalie F., Le, Sarah-Jane, Clark, Richard J., Campbell, Julie H., Craik, David J. and Daly, Norelle L. (2011). Engineering pro-angiogenic peptides using stable disulfide-rich cyclic scaffolds. Blood, 118 (25), 6709-6717. doi: 10.1182/blood-2011-06-359141
Halai, Reena, Callaghan, Brid, Daly, Norelle L., Clark, Richard J., Adams, David J. and Craik, David J. (2011). Effects of cyclization on stability, structure, and activity of alpha-conotoxin RgIA at the alpha 9 alpha 10 nicotinic acetylcholine receptor and GABA(B) receptor. Journal of Medicinal Chemistry, 54 (19), 6984-6992. doi: 10.1021/jm201060r
Dekan, Zoltan, Vetter, Irina, Daly, Norelle L., Craik, David J., Lewis, Richard J. and Alewood, Paul F. (2011). α-Conotoxin ImI incorporating stable cystathionine bridges maintains full potency and identical three-dimensional structure. Journal of the American Chemical Society, 133 (40), 15866-15869. doi: 10.1021/ja206408q
He, Wenjun, Chan, Lai Yue, Zeng, Guangzhi, Daly, Norelle L., Craik, David J. and Tan, Ninghua (2011). Isolation and characterization of cytotoxic cyclotides from Viola philippica. Peptides, 32 (8), 1719-1723. doi: 10.1016/j.peptides.2011.06.016
Dantas de Araujo, Aline, Callaghan, Brid, Nevin, Simon T., Daly, Norelle L., Craik, David J., Moretta, Melissa, Hopping, Gene, Christie, Macdonald J., Adams, David J. and Alewood, Paul F. (2011). Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted folding. Angewandte Chemie (International Edition), 50 (29), 6527-6529. doi: 10.1002/anie.201101642
Henriques, Sónia Troeira, Huang, Yen-Hua, Rosengren, K. Johan, Franquelim, Henri G., Carvalho, Filomena A., Johnson, Adam, Sonza, Secondo, Tachedjian, Gilda, Castanho, Miguel A. R. B., Daly, Norelle L. and Craik, David J. (2011). Decoding the membrane activity of the cyclotide kalata B1: The importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities. Journal of Biological Chemistry, 286 (27), 24231-24241. doi: 10.1074/jbc.M111.253393
Hashempour, Hossein, Ghassempour, Alireza, Daly, Norelle L., Spengler, Bernhard and Rompp, Andreas (2011). Analysis of cyclotides in viola ignobilis by nano liquid chromatography fourier transform mass spectrometry. Protein and Peptide Letters, 18 (7), 747-752. doi: 10.2174/092986611795446030
Poth, Aaron G., Colgrave, Michelle L., Lyons, Russell E., Daly, Norelle L. and Craik, David J. (2011). Discovery of an unusual biosynthetic origin for circular proteins in legumes. Proceedings of the National Academy of Sciences of the United State of America, 108 (25), 10127-10132. doi: 10.1073/pnas.1103660108
Daly, Norelle L. and Craik, David J. (2011). Bioactive cystine knot proteins. Current Opinion in Chemical Biology, 15 (3), 362-368. doi: 10.1016/j.cbpa.2011.02.008
Yuan, Cai, Chen, Liqing, Meehan, Edward J., Daly, Norelle, Craik, David J., Huang, Mingdong and Ngo, Jacky C. (2011). Structure of catalytic domain of matriptase in complex with sunflower trypsin inhibitor-1. BMC Structural Biology, 11 (30) 30, 30-1-30-10. doi: 10.1186/1472-6807-11-30
Mylne, Joshua S., Colgrave, Michelle L., Daly, Norelle L., Chanson, Aurelie H., Elliott, Alysha G., McCallum, Emily J., Jones, Alun and Craik, David J. (2011). Albumins and their processing machinery are hijacked for cyclic peptides in sunflower. Nature Chemical Biology, 7 (5), 257-259. doi: 10.1038/nchembio.542
Poth, Aaron G., Colgrave, Michelle L., Philip, Reynold, Kerenga, Bomai, Daly, Norelle L., Anderson, Marilyn A. and Craik, David J. (2011). Discovery of cyclotides in the Fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteins. ACS Chemical Biology, 6 (4), 345-355. doi: 10.1021/cb100388j
Daly, Norelle L., Rosengren, K. Johan, Henriques, Sonia Troeira and Craik, David J. (2011). NMR and protein structure in drug design: Application to cyclotides and conotoxins. European Biophysics Journal, 40 (4), 359-370. doi: 10.1007/s00249-011-0672-9
Daly, Norelle L., Callaghan, Brid, Clark, Richard J., Nevin, Simon T., Adams, David J. and Craik, David J. (2011). Structure and activity of alpha-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABA(B) receptor-coupled N-type calcium channels. Journal of Biological Chemistry, 286 (12), 10233-10237. doi: 10.1074/jbc.M110.196170
Akcan, M, Stroud, MR, Hansen, SJ, Clark, RJ, Daly, NL, Craik, DJ and Olson, JM (2011). Chemical re-engineering of chlorotoxin improves bioconjugation properties for tumor imaging and targeted therapy. Journal of Medicinal Chemistry, 54 (3), 782-787. doi: 10.1021/jm101018r
Lovelace, Erica S., Gunasekera, Sunithi, Alvarmo, Charlotta, Clark, Richard J., Nevin, Simon T., Grishin, Anton A., Adams, David J., Craik, David J. and Daly, Norelle L. (2011). Stabilization of α-conotoxin AuIB: Influences of disulfide connectivity and backbone cyclization. Antioxidants and Redox Signaling, 14 (1), 87-95. doi: 10.1089/ars.2009.3068
Daly, N. L. and Craik, David J. (2011). Conopeptides as novel options for pain management. Drugs of the Future, 36 (1), 25-32. doi: 10.1358/dof.2011.36.1.1561066
Cascales, Laura, Henriques, Sónia T., Kerr, Markus C., Huang, Yen-Hua, Sweet, Matthew J., Daly, Norelle L. and Craik, David J. (2011). Identification and characterization of a new family of cell penetrating peptides: Cyclic cell penetrating peptides. Journal of Biological Chemistry, Epub ahead of print (42), 36932-36943. doi: 10.1074/jbc.M111.264424
Tang, Jun, Wang, Conan K., Pan, Xulin, Yan, He, Zeng, Guangzhi, Xu, Wenyan, He, Wenjun, Daly, Norelle L., Craik, David J. and Tan, Ninghua (2010). Isolation and characterization of Bioactive Cyclotides from Viola labrilorica. Helvetica Chimica Acta, 93 (11), 2287-2295. doi: 10.1002/hlca.201000115
Ireland, David C., Clark, Richard J., Daly, Norelle L. and Craik, David J. (2010). Isolation, sequencing, and structure - Activity relationships of cyclotides. Journal of Natural Products, 73 (9), 1610-1622. doi: 10.1021/np1000413
Morales, Rodrigo A. V., Daly, Norelle L., Vetter, Irina, Mobli, Mehdi, Napier, Ian A., Craik, David J., Lewis, Richard J., Christie, MacDonald J., King, Glenn F., Alewood, Paul F. and Durek, Thomas (2010). Chemical synthesis and structure of the prokineticin Bv8. ChemBioChem, 11 (13), 1882-1888. doi: 10.1002/cbic.201000330
Tang, Jun, Wang, Conan K., Pan, Xulin, Yan, He, Zeng, Guangzhi, Xu, Wenyan, He, Wenjun, Daly, Norelle L., Craik, David J. and Tan, Ninghua (2010). Isolation and characterization of cytotoxic cyclotides from Viola tricolor. Peptides, 31 (8), 1434-1440. doi: 10.1016/j.peptides.2010.05.004
Luo, Sulan, Akondi, Kalyana Bharati, Zhangsun, Dongting, Wu, Yong, Zhu, Xiaopeng, Hu, Yuanyan, Christensen, Sean, Dowell, Cheryl, Daly, Norelle L., Craik, David J., Wang, Ching-I. Anderson, Lewis, Richard J., Alewood, Paul F. and McIntosh, J. Michael (2010). Atypical alpha-conotoxin LtIA from Conus litteratus targets a novel microsite of the alpha 3 beta 2 nicotinic receptor. Journal of Biological Chemistry, 285 (16), 12355-12366. doi: 10.1074/jbc.M109.079012
Muttenthaler, Marcus, Nevin, Simon T., Grishin, Anton A., Ngo, Shyuan T., Choy, Peng T., Daly, Norelle L., Hu, Shu-Hong, Armishaw, Christopher J., Wang, Ching-I. A., Lewis, Richard J., Martin, Jennifer L., Noakes, Peter G., Craik, David J., Adams, David J. and Alewood, Paul F. (2010). Solving the alpha-conotoxin folding problem: Efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antaqonists. Journal of the American Chemical Society, 132 (10), 3514-3522. doi: 10.1021/ja910602h
Craik, David J., Mylne, Joshua S. and Daly, Norelle L. (2010). Cyclotides: Macrocyclic peptides with applications in drug design and agriculture. Cellular and Molecular Life Sciences, 67 (1), 9-16. doi: 10.1007/s00018-009-0159-3
Daly, Norelle L., Chen, Bin, Nguyencong, Philip and Craik, David J. (2010). Structure and activity of the leaf-specific cyclotide vhl-2. Australian Journal of Chemistry, 63 (5), 771-778. doi: 10.1071/CH10007
Daly, Norelle L. and Craik, David J. (2009). Design and therapeutic applications of cyclotides. Future Medicinal Chemistry, 1 (9), 1613-1622. doi: 10.4155/FMC.09.129
Lattin, J. E., Greenwood, K. P., Daly, N. L., Kelly, G, Zidar, D. A., Clark, R. J., Thomas, W. G., Kellie, Stuart, Craik, D. J., Hume, D. A. and Sweet, M. J. (2009). Beta-arrestin 2 is required for complement C1q expression in macrophages and constrains factor-independent survival. Molecular Immunology, 47 (2-3), 340-347. doi: 10.1016/j.molimm.2009.09.012
Daly, N.L ., Rosengren, K. J. and Craik, D. J. (2009). Discovery, structure and biological activities of cyclotides. Advanced Drug Delivery Reviews, 61 (11), 918-930. doi: 10.1016/j.addr.2009.05.003
Chan, L. Y., Wang, C. K., Major, J. M., Greenwood, K. P., Lewis, R. J., Craik, D. J. and Daly, N. L. (2009). Isolation and characterization of peptides from momordica cochinchinensis seeds. JOURNAL OF NATURAL PRODUCTS, 72 (8), 1453-1458. doi: 10.1021/np900174n
Huang, Y. H., Colgrave, M. L., Daly, N. L., Keleshian, A, Martinac, B and Craik, D. J. (2009). The Biological Activity of the Prototypic Cyclotide Kalata B1 Is Modulated by the Formation of Multimeric Pores. Journal of Biological Chemistry, 284 (31), 20699-20707. doi: 10.1074/jbc.M109.003384
Gunasekera, Sunithi, Daly, Norelle L., Clark, Richard J. and Craik, David J. (2009). Dissecting the oxidative folding of circular cystine knot miniproteins. Antioxidants and Redox Signalling, 11 (5), 971-980. doi: 10.1089/ars.2008.2295
Haugaard-Jonsson, Linda M., Hossain, Mohammed Akhter, Daly, Norelle L., Craik, David J., Wade, John D. and Rosengren, K. Johan (2009). Structure of human insulin-like peptide 5 and characterization of conserved hydrogen bonds and electrostatic interactions within the relaxin framework. Biochemical Journal, 419 (3), 619-627. doi: 10.1042/BJ20082353
Millard, Emma L., Nevin, Simon T., Loughnan, Marion L., Nicke, Annette, Clark, Richard J., Alewood, Paul F., Lewis, Richard J., Adams, David J., Craik, David J. and Daly, Norelle L. (2009). Inhibition of neuronal nicotinic acetylcholine receptor subtypes by alpha-conotoxin GID and analogues. Journal of Biological Chemistry, 284 (8), 4944-4951. doi: 10.1074/jbc.M804950200
Daly, N. L. and Craik, D. J. (2009). Structural studies of conotoxins. IUBMB Life, 61 (2), 144-150. doi: 10.1002/iub.158
Rosengren, K. Johan, Daly, Norelle L. and Craik, David J. (2009). NMR of Peptide Toxins. Annual Reports on NMR Spectroscopy, 68 (C), 89-147. doi: 10.1016/S0066-4103(09)06802-1
Haugaard-Jönsson, Linda M., Hossain, Mohammed Akhter, Daly, Norelle L., Bathgate, Ross A. D., Wade, John D., Craik, David J. and Rosengren, K. Johan (2008). Structure of the R3/I5 chimeric relaxin peptide, a selective GPCR135 and GPCR142 agonist. The Journal of Biological Chemistry, 283 (35), 23811-23818. doi: 10.1074/jbc.M800489200
Jin, Ai-Hua, Daly, N. L., Nevin, S. T., Wang, C. I. A., Dutertre, S., Lewis, R. J., Adams, D. J., Craik, D. J. and Alewood, P. F. (2008). Molecular engineering of conotoxins: The importance of loop size to alpha-conotoxin structure and function. Journal of Medicinal Chemistry, 51 (18), 5575-5584. doi: 10.1021/jm800278k
Hossain, M. A., Rosengren, K. J., Haugaard-Jonsson, L. M., Zhang, S., Layfield, S., Ferraro, T., Daly, N. L., Tregear, G. W., Wade, J. D. and Bathgate, R. A. D. (2008). The A-chain of human relaxin family peptides has distinct roles in the binding and activation of the different relaxin family peptide receptors. Journal of Biological Chemistry, 283 (25), 17287-17297. doi: 10.1074/jbc.M801911200
Gunasekera, Sunithi, Foley, Fiona M., Clark, Richard J., Sando, Lillian, Fabri, Louis J., Craik, David J. and Daly, Norelle L. (2008). Engineering stablized vascular endothelial growth factor-A antagonists: synthesis, structural characterization and bioactivity of grafted analogues of cyclotides. Journal of Medicinal Chemistry, 51 (24), 7697-7704. doi: 10.1021/jm800704e
Cemazar, M., Joshi, A., Daly, N. L., Mark, A. E. and Craik, D. J. (2008). The structure of a two-disulfide intermediate assists in elucidating the oxidative folding pathway of a cyclic cystine knot protein. Structure, 16 (6), 842-851. doi: 10.1016/j.str.2008.02.023
Imperial, Julita S., Chen, Ping, Sporning, Annett, Terlau, Heinrich, Daly, Norelle L., Craik, David J., Alewood, Paul F. and Olivera, Baldormero M. (2008). Tyrosine-rich conopeptides affect voltage-gated K+ channels. The journal of biological chemistry, 283 (34), 23026-23032. doi: 10.1074/jbc.M800084200
Simonsen, S. M., Sando, L., Rosengren, K. J., Wang, C. K., Colgrave, M. L., Daly, N. L. and Craik, D. J. (2008). Alanine Scanning mutagenesis of the prototypic cyclotide reveals a cluster of residues essential for bioactivity. Journal of Biological Chemistry, 283 (15), 9805-9813. doi: 10.1074/jbc.M709303200
Dutertre, Sébastien, Croker, Daniel, Daly, Norelle L., Andersson, Åsa, Muttenthaler, Markus, Lumsden, Natalie G., Craik, David J., Alewood, Paul F., Guillon, Gilles and Lewis, Richard J. (2008). Conopressin-T from Conus tulipa reveals an antagonist switch in vasopressin-like peptide. Journal of Biological Chemistry, 283 (11), 7100-7108. doi: 10.1074/jbc.M706477200
Clark, Richard J., Daly, Norelle L., Halai, Reena, Nevin, Simon T., Adams, David J. and Craik, David J. (2008). The three-dimensional structure of the analgesic alpha-conotoxin, RgIA. FEBS Letters, 582 (5), 597-602. doi: 10.1016/j.febslet.2008.01.027
Craik, David J., Clark, Richard J. and Daly, Norelle L. (2008). Cyclotides and conotoxins ultra-stable disulfide-rich peptides. Chimica Oggi -Chemistry Today, 26 (4), 20-22.
Jin, Ai-Hua, Brandstaetter, Hemma, Nevin, Simon T., Tan, Chia Chia, Clark, Richard J., Adams, David J., Alewood, Paul F., Craik, David J. and Daly, Norelle L. (2007). Structure of alpha-conotoxin BuIA: Influences of disulfide connectivity on structural dynamics. BMC Structural Biology, 7 (28) 28, 1-13. doi: 10.1186/1472-6807-7-28
Craik, D. J and Daly, N. L (2007). NMR as a tool for elucidating the structures of circular and knotted proteins. Molecular Biosystems, 3 (4), 257-265. doi: 10.1039/b616856f
Craik, D. J., Cemazar, M. and Daly, N. L. (2007). The chemistry and biology of cyclotides. Current Opinion In Drug Discovery & Development, 10 (2), 176-184.
Greenwood, K. P., Daly, N. L., Brown, D. L., Stow, J. L. and Craik, D. J. (2007). The cyclic cystine knot miniprotein MCoTI-II is internalized into cells by macropinocytosis. International Journal of Biochemistry & Cell Biology, 39 (12), 2252-2264. doi: 10.1016/j.biocel.2007.06.016
Daly, Norelle L., Chen, Y, Rosengren, KJ, Marx, UC, Phillips, ML, Waring, AJ, Wang, W, Lehrer, RI and Craik, David J. (2007). Retrocyclin-2: Structural analysis of a potent anti-HIV θ-defensin. Biochemistry, 46 (35), 9920-9928. doi: 10.1021/bi700720e
Plan, M. R. R, Goransson, U, Clark, R. J, Daly, N. L, Colgrave, M. L and Craik, D.J (2007). The cyclotide fingerprint in Oldenlandia affinis: Elucidation of chemically modified, linear and novel macrocyclic peptides. Chembiochem, 8 (9), 1001-1011. doi: 10.1002/cbic.200700097
Gunasekera, S, Daly, NL, Clark, RJ, Simonsen, SM, Foley, FM, Saska, I, Lin, F, Wade, JD, Anderson, MA and Craik, DJ (2007). The conserved N-terminal repeat of the plant cyclotides does not assist folding of cyclotide precursor in vitro. Biopolymers, 88 (4), 540-540.
Craik, D. J, Clark, R. J and Daly, N. L (2007). Potential therapeutic applications of the cyclotides and related cystine knot mini-proteins. Expert Opinion On Investigational Drugs, 16 (5), 595-604. doi: 10.1517/13543784.16.5.595
Rosengren, K. Johan, Daly, Norelle L., Fornander, Liselotte M., Jonsson, Linda M. H., Shirafuji, Yoshinori, Qu, Xiaoqing, Vogel, Hans J., Ouellette, Andre J. and Craik, David J. (2006). Structural and functional characterization of the conserved salt bridge in mammalian Paneth cell alpha-defensins - Solution structures of mouse cryptdin-4 AND (E15D)-cryptdin-4. Journal of Biological Chemistry, 281 (38), 28068-28078. doi: 10.1074/jbc.M604992200
Rosengren, K. J., Zhang, S., Lin, F., Daly, N. L., Scott, D. J., Hughes, R. A., Bathgate, R. A. D., Craik, D. J. and Wade, J. D. (2006). Solution structure and characterization of the LGR8 receptor binding surface of insulin-like peptide 3. Journal of Biological Chemistry, 281 (38), 28287-28295. doi: 10.1074/jbc.M603829200
Armishaw, Christopher J., Daly, Norelle L., Nevin, Simon T., Adams, David J., Craik, David J. and Alewood, Paul F. (2006). Alpha-selenoconotoxins, a new class of potent alpha(7) neuronal nicotinic receptor antagonists. Journal of Biological Chemistry, 281 (20), 14136-14143. doi: 10.1074/jbc.M512419200
Ireland, David C., Colgrave, Michelle L., Nguyencong, Philip, Daly, Norelle L. and Craik, David J. (2006). Discovery and characterization of a linear cyclotide from Viola odorata: Implications for the processing of circular proteins. Journal of Molecular Biology, 357 (5), 1522-1535. doi: 10.1016/j.jmb.2006.01.051
Rosengren, K. J., Lin, F., Bathgate, R. A. D., Tregear, G. W., Daly, N. L., Wade, J. D. and Craik, D. J. (2006). Solution structure and novel insights into the determinants of the receptor specificity of human relaxin-3. Journal of Biological Chemistry, 281 (9), 5845-5851. doi: 10.1074/jbc.M511210200
Daly, N. L., Clark, R. J., Plan, M. R. and Craik, D. J. (2006). Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motif. Biochemical Journal, 393 (Part 3), 619-626. doi: 10.1042/BJ20051371
Gunasekera, S., Daly, N. L., Anderson, M. A. and Craik, D. J. (2006). Chemical synthesis and biosynthesis of the cyclotide family of circular proteins. Iubmb Life, 58 (9), 515-524. doi: 10.1080/15216540600889532
Clark, R. J., Daly, N. L. and Craik, D. J. (2006). Structural plasticity of the cyclic-cystine-knot framework: implications for biological activity and drug design. Biochemical Journal, 394 (Part 1), 85-93. doi: 10.1042/BJ20051691
Craik, D. J., Cemazar, M. and Daly, N. L. (2006). The cyclotides and related macrocyclic peptides as scaffolds in drug design. Current Opinion In Drug Discovery & Development, 9 (2), 251-260.
Bansal, P. S., Grieve, P. A., Marschke, R. J., Daly, N. L., McGhie, E., Craik, D. J. and Alewood, P. F. (2006). Chemical synthesis and structure elucidation of bovine kappa-casein (1-44). Biochemical And Biophysical Research Communications, 340 (4), 1098-1103. doi: 10.1016/j.bbrc.2005.12.115
Craik, D. J., Cemazar, M., Wang, C. K. L. and Daly, N. L. (2006). The cyclotide family of circular miniproteins: Nature's combinatorial peptide template. Biopolymers, 84 (3), 250-266. doi: 10.1002/hip.20451
Marx, U. C., Daly, N. L. and Craik, D. J. (2006). NMR of conotoxins: structural features and an analysis of chemical shifts of post-translationally modified amino acids. Magnetic Resonance In Chemistry, 44 (Sp. Iss. SI), S41-S50. doi: 10.1002/mrc.1821
Lovelace, E. S., Armishaw, C. J., Colgrave, M. L., Wahlstrom, M. E., Alewood, P. F., Daly, N. L. and Craik, D. J. (2006). Cyclic MrIA: A stable and potent cyclic conotoxin with a novel topological fold that targets the norepinephrine transporter. Journal of Medicinal Chemistry, 49 (22), 6561-6568. doi: 10.1021/jm060299h
Daly, N. L., Chen, Y. K., Foley, F. M., Bansal, P. S., Bharathi, R., Clark, R. J., Sommerhoff, C. P. and Craik, D. J. (2006). The absolute structural requirement for a proline in the P3 '-position of Bowman-Birk protease inhibitors is surmounted in the minimized SFTI-1 scaffold. Journal of Biological Chemistry, 281 (33), 23668-23675. doi: 10.1074/jbc.M601426200
Gallo, S. A., Wang, W., Rawat, S. S., Jung, G., Waring, A. J., Cole, A. M., Lu, H., Yan, X. X., Daly, N. L., Craik, D. J., Jiang, S. B., Lehrer, R. I. and Blumenthal, R. (2006). theta-defensins prevent HIV-1 Env-mediated fusion by binding gp41 and blocking 6-helix bundle formation. Journal of Biological Chemistry, 281 (27), 18787-18792. doi: 10.1074/jbc.M602422200
Cemazar, M., Daly, N. L., Haggblad, S., Lo, K. P., Yulyaningsih, E. and Craik, D. J. (2006). Knots in rings - The circular knotted protein momordica cochinchinensis trypsin inhibitor-II folds via a stable two-disulfide intermediate. Journal of Biological Chemistry, 281 (12), 8224-8232. doi: 10.1074/jbc.M513399200
Imperial, J. S., Bansal, P. S., Alewood, P. F., Daly, N. L., Craik, D., Sporning, A., Terlau, H., Lopez-Vera, E., Bandyopadhyay, P. K. and Olivera, B. M. (2006). A novel conotoxin inhibitor of Kv1.6 channel and nAChR subtypes defines a new superfamily of conotoxins. Biochemistry, 45 (27), 8331-8340. doi: 10.1021/bi060263r
Chen, Bin, Colgrave, Michelle L., Daly, Norelle L., Rosengren, K. Johan, Gustafson, Kirk R. and Craik, David J. (2005). Isolation and characterization of novel cyclotides from Viola hederaceae - Solution structure and anti-HIV activity of vhl-1, a leaf-specific expressed cyclotide. Journal of Biological Chemistry, 280 (23), 22395-22405. doi: 10.1074/jbc.M501737200
Craik, DJ and Daly, NL (2005). Oxidative folding of the cystine knot motif in cyclotide proteins. Protein And Peptide Letters, 12 (2), 147-152. doi: 10.2174/0929866053005863
Jennings, Cameron V., Rosengren, K. Johan, Daly, Norelle L., Plan, Manuel, Stevens, Jackie, Scanlon, Martin J., Waine, Clement, Norman, David G., Anderson, Marilyn A. and Craik, David J. (2005). Isolation, solution structure, and insecticidal activity of Kalata B2, a circular protein with a twist: Do Mobius strips exist in nature?. Biochemistry, 44 (3), 851-860. doi: 10.1021/bi047837h
Koltay, A., Daly, N. L., Gustafson, K. R. and Craik, D. J. (2005). Structure of circulin B and implications for antimicrobial activity of the cyclotides. International Journal of Peptide Research And Therapeutics, 11 (1), 99-106. doi: 10.1007/s10989-004-1722-2
Clark, R. J., Fischer, H., Dempster, L., Daly, N. L., Rosengren, K. J., Nevin, S. T., Meunier, F. A., Adams, D. J. and Craik, D. J. (2005). Engineering stable peptide toxins by means of backbone cyclization: Stabilization of the alpha-conotoxin MII. Proceedings of The National Academy of Sciences of The United States of America, 102 (39), 13767-13772. doi: 10.1073/pnas.0504613102
Nilsson, K. P. R., Lovelace, E. S., Caesar, C. E., Tynngard, N., Alewood, P. F., Johansson, H. M., Sharpe, I. A., Lewis, R. J., Daly, N. L. and Craik, D. J. (2005). Solution structure of χ-conopeptide MrIA, a modulator of the human norepinephrine transporter. Biopolymers, 80 (6), 815-823. doi: 10.1002/bip.20302
Simonsen, Shane M., Daly, Norelle L. and Craik, David J. (2004). Capped acyclic permutants of the circular protein kalata B1. Febs Letters, 577 (3), 399-402. doi: 10.1016/j.febslet.2004.10.034
Daly, Norelle L., Gustafson, Kirk R. and Craik, David J. (2004). The role of the cyclic peptide backbone in the anti-HIV activity of the cyclotide kalata B1. FEBS Letters, 574 (1-3), 69-72. doi: 10.1016/j.febslet.2004.08.007
Nourse, A., Trabi, M., Daly, N. L. and Craik, D. J. (2004). A comparison of the self-association behavior of the plant cyclotides kalata B1 and kalata B2 via analytical ultracentrifugation. Journal of Biological Chemistry, 279 (1), 562-570. doi: 10.1074/jbc.M306826200
Daly, N. L., Ekberg, J. A., Thomas, L., Adams, D. J., Lewis, R. J. and Craik, D. J. (2004). Structures of mu O-conotoxins from Conus marmoreus - Inhibitors of tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels in mammalian sensory neurons. Journal of Biological Chemistry, 279 (24), 25774-25782. doi: 10.1074/jbc.M313002200
Craik, D. J., Daly, N. L., Mulvenna, J., Plan, M. R. and Trabi, M. (2004). Discovery, structure and biological activities of the cyclotides. Current Protein & Peptide Science, 5 (5), 297-315. doi: 10.2174/1389203043379512
Millard, E. L., Daly, N. L. and Craik, D. J. (2004). Structure-activity relationships of alpha-conotoxins targeting neuronal nicotinic acetylcholine receptors. European Journal of Biochemistry, 271 (12), 2320-2326. doi: 10.1111/j.1432-1033.2004.04148.x
Barry, D. G., Daly, N. L., Bokesch, H. R., Gustafson, K. R. and Craik, D. J. (2004). Solution structure of the cyclotide palicourein: Implications for the development of a pharmaceutical framework. Structure, 12 (1), 85-94. doi: 10.1016/j.str.2003.11.019
Dutton, J. L., Renda, R. F., Waine, C., Clark, R. J., Daly, N. L., Jennings, C. V., Anderson, M. A. and Craik, D. J. (2004). Conserved structural and sequence elements implicated in the processing of gene-encoded circular proteins. Journal of Biological Chemistry, 279 (45), 46858-46867. doi: 10.1074/jbc.M407421200
Rosengren, K. J., Daly, N. L., Plan, M. R., Waine, C. and Craik, D. J. (2003). Twists, knots, and rings in proteins: Structural definition of the cyclotide framework. Journal of Biological Chemistry, 278 (10), 8606-8616. doi: 10.1074/jbc.M211147200
Daly, N. L., Clark, R. J. and Craik, D. J. (2003). Disulfide folding pathways of cystine knot proteins: Tying the knot within the circular backbone of the cyclotides. The Journal of Biological Chemistry, 278 (8), 6314-6322. doi: 10.1074/jbc.M210492200
Nicke, Annette, Loughnan, Marion L., Millard, Emma L., Alewood, Paul F., Adams, David J., Daly, Norelle L., Craik, David J. and Lewis, Richard J. (2003). Isolation, structure, and activity of GID, a novel alpha 4/7-conotoxin with an extended N-terminal sequence. Journal of Biological Chemistry, 278 (5), 3137-3144. doi: 10.1074/jbc.M210280200
Craik, D. J., Daly, N. L., Saska, I., Trabi, M. and Rosengren, K. J. (2003). Structures of naturally occurring circular proteins from bacteria. Journal of Bacteriology, 185 (14), 4011-4021. doi: 10.1128/JB.185.14.4011-4021.2003
Craik, David J., Barry, Daniel G., Clark, Richard J., Daly, Norelle L. and Sando, Lillian (2003). Structure-function studies of the plant cyclotides: The role of a circular protein backbone. Toxin Reviews, 22 (4), 555-576. doi: 10.1081/TXR-120026914
Daly, N. L., Clark, R. J., Goransson, U. and Craik, D. J. (2003). Diversity in the disulfide folding pathways of cystine knot peptides. Letters in Peptide Science, 10 (5-6), 523-531. doi: 10.1007/BF02442584
Rosengren, K. J., Clark, R. J., Daly, N. L., Goransson, U., Jones, A. and Craik, D. J. (2003). Microcin J25 has a threaded sidechain-to-backbone ring structure and not a head-to-tail cyclized backbone. Journal of the American Chemical Society, 125 (41), 12464-12474. doi: 10.1021/JA0367703
Jones, C., Daly, N. L., Cobine, P. A., Craik, D. J. and Dameron, C. (2003). Structure and metal binding studies of the second copper binding domain of the Menkes ATPase. Journal of Structural Biology, 143 (3), 209-218. doi: 10.1016/j.jsb.2003.08.008
Barry, D. G., Daly, N. L., Clark, R. J., Sando, L. and Craik, D. J. (2003). Linearization of a naturally occurring circular protein maintains structure but eliminates hemolytic activity. Biochemistry, 42 (22), 6688-6695. doi: 10.1021/bi027323n
Craik, D. J., Anderson, M. A. and Daly, N. L. (2003). Circular Proteins tied in knots. Today's Life Science, January/Fe, 28-32.
Craik, David J., Barry, Daniel G., Clark, Richard J., Daly, Norelle L. and Sando, Lillian (2003). Structure-function studies of the plant cyclotides: the role of a circular protein backbone. Journal of Toxicology: Toxin Reviews, 22 (4), 555-576. doi: 10.1081/TXR-120026914
Rosengren, K. Johan, Wilson, David, Daly, Norelle L., Alewood, Paul F. and Craik, David J. (2002). Solution Structures of the cis- and trans-Pro30 Isomers of a Novel 38-Residue Toxin from the Venom of Hadronyche Infensa sp. that Contains a Cystine-Knot Motif within Its Four Disulfide Bonds. Biochemistry, 41 (10), 3294-3301. doi: 10.1021/bi011932y
Craik, D. J., Simonsen, S. and Daly, N. L. (2002). The cyclotides: Novel macrocyclic peptides as scaffolds in drug design. Current Opinion In Drug Discovery & Development, 5 (2), 251-260.
Craik, D. J., Daly, N. L., Plan, M. R., Salim, A. A. and Sando, L. (2002). Structure and function of plant toxins (with emphasis on cystine knot toxins). Journal of Toxicology-toxin Reviews, 21 (3), 229-271. doi: 10.1081/TXR-120014405
Wilce, Jackie A., Daly, Norelle L. and Craik, David J. (2002). Synthesis and structural analysis of the N-terminal domain of the thyroid hormone-binding protein transthyretin. Clinical Chemistry And Laboratory Medicine, 40 (12), 1221-1228. doi: 10.1515/CCLM.2002.212
Craik, David J., Anderson, Marilyn A., Barry, Daniel G., Clark, Richard J., Daly, Norelle L., Jennings, Cameron V. and Mulvenna, Jason P. (2001). Discovery and structures of the cyclotides: novel macrocyclic peptides from plants. Letters in Peptide Science, 8 (3-5), 119-128. doi: 10.1007/BF02446507
Rosengren, K. J., Daly, N. L., Scanlon, M. J. and Craik, D. J. (2001). Solution structure of BSTI: A new trypsin inhibitor from skin secretions of Bombina bombina. Biochemistry, 40 (15), 4601-4609. doi: 10.1021/bi002623v
Craik, D. J., Daly, N. L. and Waine, C. (2001). The cystine knot motif in toxins and implications for drug design. Toxicon, 39 (1), 43-60. doi: 10.1016/S0041-0101(00)00160-4
Felizmenio-Quimio, M. E., Daly, N. L. and Craik, D. J. (2001). Circular proteins in plants - Solution structure of a novel macrocyclic trypsin inhibitor from Momordica cochinchinensis. Journal of Biological Chemistry, 276 (25), 22875-22882. doi: 10.1074/jbc.M101666200
Daly, N. L., Hoffmann, R., Otvos, L. J. and Craik, D. J. (2000). Role of phosphorylation in the conformation of tau peptides implicated in Alzheimer's disease. Biochemistry, 39 (30), 9039-9046. doi: 10.1021/bi0004807
Daly, NL and Craik, DJ (2000). Acyclic permutants of naturally occurring cyclic proteins - Characterization of cystine knot and beta-sheet formation in the macrocyclic polypeptide kalata B1. Journal of Biological Chemistry, 275 (25), 19068-19075. doi: 10.1074/jbc.M000450200
Daly, N. L. and Craik, D. J. (2000). Acyclic permutants of naturally occurring cyclic proteins. The Journal of Biological Chemistry, 275 (25), 19068-19075.
Craik, D. J., Daly, N. L., Bond, T. J. and Waine, C. (1999). Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif. Journal of Molecular Biology, 294 (5), 1327-1336. doi: 10.1006/jmbi.1999.3383
Daly, N. L., Love, S., Alewood, P. F. and Craik, D. J. (1999). Chemical synthesis and folding pathways of large cyclic polypeptide: Studies of the cystine knot polypeptide kalata B1. Biochemistry, 38 (32), 10606-10614. doi: 10.1021/bi990605b
Gehrmann, John, Daly, Norelle L., Alewood, Paul F. and Craik, David J. (1999). Solution structure of alpha-conotoxin ImI by H-1 nuclear magnetic resonance. Journal of Medicinal Chemistry, 42 (13), 2364-2372. doi: 10.1021/jm990114p
Daly, NL, Koltay, A, Gustafson, KR, Boyd, MR, Casas-Finet, JR and Craik, DJ (1999). Solution Structure by NMR of Circulin A: A Macrocyclic Knotted Peptide Having Anti-HIV Activity. Journal of Molecular Biology, 285 (1), 333-345. doi: 10.1006/jmbi.1998.2276
Daly, Norelle L., Scanlon, Martin J., Djordjevic, Julianne T., Kroon, Paulus A. and Smith, Ross (1995). Three-dimensional structure of a cysteine-rich repeat from the low-density lipoprotein receptor. Proceedings of the National Academy of Sciences, 92 (14), 6334-6338. doi: 10.1073/pnas.92.14.6334
Conference Papers
Bhattacharya, Samit, Ammirati, Mark, Borzilleri, Kris, Cheneval, Olivier, Chrunyk, Boris, Craik, David, Daly, Norelle, Dullea, Robert, Griffor, Matthew, Kamlet, Adam, Limberakis, Chris, Sahasrabudhe, Parag, Liu, Shenping, Loria, Paula, Mc Clure, Kim, Menhaji-Klotz, Elnaz, Petersen, Donna, Piotrowski, David, Popovska-Gorevski, Marina, Price, David, Reyes, Allan, Ruggeri, Roger, Schroeder, Christina, Song, Kun, Swedberg, Joakim, Stock, Ingrid, Tu, Meihua and Withka, Jane (2017). Small molecule and peptidic ligands as PCSK9-LDLR inhibitors. 254th National Meeting and Exposition of the American-Chemical-Society (ACS) on Chemistry's Impact on the Global Economy, Washington, DC, 20-24 August 2017 . Washington, DC, United States: American Chemical Society.
Henriques, S. T., Huang, Y. -H., Castanho, M. A. R. B., Daly, N. L. and Craik, D. J. (2012). The Importance of the cell membrane on the mechanism of action of cyclotides. 32nd European Peptide Symposium "Peptides 2012", Athens, Greece, 02-07 September 2012. West Sussex, United Kingdom: John Wiley and Sons. doi: 10.1002/psc.2449
Chan, L. A., Gunasekera, S., Henriques, S. T., Worth, N. F., Le, S., Clark, R. J., Campbell, J. H., Craik, D. J. and Daly, N. L. (2012). Engineering pro-angiogenic peptides using stable disulfide-rich scaffolds. 32nd European Peptide Symposium, Athens, Greece, 2-7 September 2012. Chichester, West Sussex, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.2448
Franco, Aldo, Heighinian, Mari, Mejia, Monica, McCall, Jessica, Nag, Shiva, Akondi, Kalyana, Melaun, Christian, Daly, Norelle, Luetje, Charles W., Alewood, Paul F., Craik, David J., Godenschwege, Tanja, Adams, David J. and Mari, Frank (2012). Discovery, characterization, and functional implications of conotoxins from cone snails species of the Americas. 17th World Congress of the International-Society-on-Toxinology (IST)/Venom Week/4th International Scientific Symposium on All Things Venomous, Honolulu, Hawaii, United States, 8-13 July 2012. Kidlington, Oxford, United Kingdom: Pergamon. doi: 10.1016/j.toxicon.2012.04.106
Craik, D., Poth, A., Colgrave, M., Akcan, M., Oku, B., Chan, A. and Daly, N. (2011). Discovery and applications of naturally occurring cyclic peptides. 59th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research, Antalya, Turkey, 4-9 September 2011. Stuttgart, Germany: Georg Thieme Verlag. doi: 10.1055/s-0031-1282086
Muttenthaler, M., Gruber, C. W., Andersson, A., Vetter, I., Nevin, S. T., Grishin, A. A., Dutertre, S., Daly, N. L., Craik, D. J., Adams, D. J., Lewis, R. J. and Alewood, P. F. (2011). Conotoxins - blueprints for GPCR drug discovery?. 22nd American Peptide Symposium, San Diego, CA, United States, 25-30 June 2011. Hoboken, NJ, United States: John Wiley & Sons.
Craik, David J., Daly, Norelle L., Chan, Angeline, Mylne, Joshua S., Poth, Aaron and Colgrave, Michelle (2011). Naturally Occurring Cyclic Peptides as Templates in Drug Design. 22nd American Peptide Symposium, San Diego Ca, Jun 25-30, 2011. Malden MA, United States: Wiley-Blackwell Publishing.
Henriques, Sonia Troeira, Huang, Yen-Boa, Rosengren, K. Johan, Franquelim, Henri G., Carvalho, Filomena A., Johnson, Adam, Sonza, Second, Tachedjian, Gilda, Castanho, Miguel A. R. B., Daly, Norelle L. and Craik, I. David J. (2011). Differences in bactericidal, hemolytic and anti-HIV efficiencies of the cyclotide kalata B1 are explained by distinct cell membrane compositions. 22nd American Peptide Symposium, San Diego, California, 25-30 June 2011 . Hoboken, NJ, United States: John Wiley & Sons.
Manuel Plan, Rosengren, K. Johan, Sando, Lillian, Daly, Norelle L. and Craik, David J. (2010). Structural and biochemical characteristics of the cyclotide kalata B5 from Oldenlandia affinis. 1st International Conference on Circular Proteins, Heron Island, Qld, Australia, 18-21 October 2009. Hoboken, N. J., U.S.: John Wiley & Sons. doi: 10.1002/bip.21409
Haugaard-Kedstrom, M., Hossain, M. A., Daly, N. L., Bathgate, R. A. D., Craik, D. J., Wade, J. D. and Rosengren, K. J. (2010). Characterisation of the human INSL5 solution structure. EPS 2010: The 31st European Peptide Symposium, Copenhagen, Denmark, 5-9 September 2010. Bognor Regis, West Sussex, U.K.: John Wiley & Sons. doi: 10.1002/psc.1303
Haugaard-Kedström, M., Hossain, M. A., Daly, N. L., Bathgate, R. A. D., Wade, J. D., Craik, D. J. and Rosengren, K. J. (2010). Structural characterization of the relaxin-3IINSL5 chimera peptide: A selective RXFP3 and RXFP4 agonist. EPS 2010: The 31st European Peptide Symposium, Copenhagen, Denmark, 5-9 September 2010. Bognor Regis, West Sussex, U.K.: John Wiley & Sons. doi: 10.1002/psc.1301
Danks, J.A., Scanlon, D.B., Daly, N., Craik, D.J., Sneddon, W.B. and Richardson, S.J. (2009). Structure and function of Fugu parathyroid hormone 1 (-34). 2nd Joint Meeting of the International Bone and Mineral-Society/Australian New Zealand-Bone and Mineral Society, Sydney, Australia, 21-25 March 2009. United States: Elsevier Inc.. doi: 10.1016/j.bone.2009.01.461
Henriques, S., Huang, Y., Daly, N. and Craik, D. (2009). How Do Cyclotides Exert Their Mode of Action? the Importance of Cell Membranes On Their Diverse Activities. 21st American Peptide Symposium, Bloomington, Indiana, USA, 7-12 June 2009. United States: John Wiley & Sons, Inc.. doi: 10.1002/bip.21223
Henriques, S., Huang, Y., Daly, N. and Craik, D. (2009). How do cyclotides exert their mode of action? the importance of cell membranes on their diverse activities. 21st American Peptide Symposium, Bloomington, Indiana, USA, 7-12 June 2009. United States: John Wiley & Sons, Inc.. doi: 10.1002/bip.21222
Akcan, M, Stroud, MR, Hansen, SA, Daly, N, Craik, D and Olson, J (2009). Tumor Paint: a Scorpion Toxin Peptide That Targets Fluorescent Dye to Brain Tumor Cells for Real-Time Intraoperative Imaging. Joint Meeting of the Society-forNeuro-Oncology/American-Association-of-Neurological -Surgeons/Congress of Neurological Surgeons, New Orleans La, Oct 22-24, 2009. DURHAM: DUKE UNIV PRESS.
Ireland, David C., Colgrave, Michelle L., Daly, Norelle L. and Craik, David J. (2009). The discovery and development of a natural combinatorial peptide template: The cyclotides. American Peptide Symposium (20th), New York, United States, 2009. New York, United States: Springer. doi: 10.1007/978-0-387-73657-0_205
Rosengren, K. Johan, Bathgate, Ross A. D., Craik, David J., Daly, Norelle L., Haugaard-Jonsson, Linda M., Hossain, Mohammed Akhter and Wade, John D. (2009). Structural insights into the function of relaxins. Relaxin and Related Peptides Fifth International Conference, Maui, Hawaii, USA, 18-23 May, 2008. New York, U.S.A.: The Academy. doi: 10.1111/j.1749-6632.2009.03833.x
Haugaard-Jonsson, Linda M., Hossain, Mohammed Akhter, Daly, Norelle L., Bathgate, Ross A. D., Wade, John D., Craik, David J. and Rosengren, K. Johan (2009). Structural properties of relaxin chimeras: NMR characterization of the R3/I5 relaxin peptide. Relaxin and Related Peptides Fifth International Conference, Maui, Hawaii, USA, 18-23 May, 2008. New York, U.S.A.: The Academy. doi: 10.1111/j.1749-6632.2008.03805.x
Daly, Norelle L., Yi, Chen K., Rosengren, K. Johan, Marx, Ute C., Phillips, Martin L., Waring, Alan J., Wang, Wei, Lehrer, Robert I. and Craik, David J. (2009). Retrocyclin-2: A potent anti-HIV theta-defensin that forms a cyclic cystine ladder structural motif. 20th American Peptide Society Symposium, Montreal, Canada, 26-30 June 2007. New York, United States: Springer New York LLC. doi: 10.1007/978-0-387-73657-0_254
Muttenthaler, M., Nevin, S. T., Grishin, A. A., Ngo, S. T., Choy, P. T., Daly, N. L., Hu, S-H., Martin, J. L., Noakes, P. G., Craik, D. J., Adams, D. J. and Alewood, P. F. (2008). Selenocysteine in peptide folding and drug design. XXth International Symposium on Medicinal Chemistry (EFMC-ISMC 2008), Vienna, Austria, 31 August - 4 September 2008.
Adams, D. J., Alewood, P. F., Choy, P. T., Craik, D. J., Daly, N. L., Grishin, A. A., Hu, S-H., Martin, J. L., Muttenthaler, M., Nevin, S. T., Ngo, S. T. and Noakes, P. G. (2008). Selenocysteine in peptide drug design. Royal Australian Chemical Institute (RACI) Annual Scientific Meeting: Drug Discovery and Development, Couran Cove Island Resort, Queensland, Australia, 13 - 17 July 2008.
Greenwood, K. P., Daly, N. L., Brown, D. L., Stow, J. L. and Craik, D. J. (2007). The cyclic cystine knot miniprotein MCoTI-II crosses the plasma membrane by macropinocytosis. 20th American Peptide Society Symposium, Montreal, Canada, 26-30 June 2007 . Hoboken, NJ, United States: John Wiley & Sons.
Lovelace, Erica S., Armishaw, Christopher J., Colgrave, Michelle L., Alewood, Paul F., Daly, Norelle L. and Craik, David J. (2006). Backbone cyclization improves the enzymatic stability of chi-conotoxin, MrIA, whilst maintaining its structure and NET-modulating activity. 19th American Peptide Symposium, San Diego, CA, United States, 18-23 June 2005. New York, United States: Springer. doi: 10.1007/978-0-387-26575-9_283
Rosengren, KJ, Jen, FEC, Clark, RJ, Goransson, U, Daly, NL and Craik, DJ (2005). A novel threaded ring structure for the antimicrobial peptide microcin J25. Peptides 2004: 3rd International Peptide Symposium / 28th European Peptide Symposium, Prague, Czech Republic, 5 - 10 September 2004. Geneva, Switzerland: Kenes International.
Lovelace, E. S., Armishaw, C. J., Colgrave, M. L., Alewood, P. F., Daly, N. L. and Craik, D. J. (2005). Backbone cyclization improves the enzymatic stability of chi-conotoxin, MrIA, whilst maintaining its structure and NET-modulating activity. 19th American Peptide Symposium, San Diego, California, US, 18-23 June, 2005. Hoboken, NJ: Wiley Interscience.
Lattin, Jane E., Blomberg, Lovisa M., Daly, Norelle L., Craik, David J., Robinson, Jodie A., Kellie, Stuart, Hume, David A. and Sweet, Matthew J. (2005). Beta-arrestin expression and function in macrophages. 7th World Congress on Inflammation: Inflammation 2005: Inflammation, the Key to much pathology, Melbourne, Australia, 20 - 24 August 2005. Basel, Switzerland: Birkhaeuser.
Craik, David J., Daly, Norelle L., Colgrave, Michelle L. and Rosengren, K. Johan (2004). Discovery and applications of the cyclotides: Circular proteins from plants. 18th American Peptide Symposium, Boston, MA, U.S.A., 19-23 July 2003. Washington, DC, USA: American Chemical Society.
Plan, MR, Goransson, U, Rosengren, KJ, Clark, RJ, Daly, NL, Evert, P, Chen, C, Cagauan, AG and Craik, DJ (2004). Cyclotides: Novel Peptidic Pesticides for Plant Protection. CHICHESTER: JOHN WILEY & SONS LTD.
Clark, RJ, Dempster, L, Daly, NL, Rosengren, KJ and Craik, DJ (2004). Design, Synthesis and Structural Studies of Cyclic Alpha-Conotoxins. CHICHESTER: JOHN WILEY & SONS LTD.
Craik, D. J., Rosengren, K. J., Clark, R. J., Daly, N. L. and Goransson, U. (2004). A novel threaded ring structure for the antimicrobial peptide microcin J25. 3rd International and 28th European Peptide Symposium, Prague, Czech Republic, 5–10 September 2004. West Sussex, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.617
Armishaw, CJ, Daly, NL, Nevin, ST, Adams, DJ, Craik, DJ and Alewood, PF (2004). Increasing the Conformational Stability of Alpha-Conotoxin Imi by Substitution of Disulfide Bonds with Isosteric Diselenide Bonds. MALDEN: WILEY-BLACKWELL.
Jones, CE, Cobine, PA, Daly, N, Craik, D, Dameron, CT and Moore, MR (2001). Structure of the second copper binding domain of the Menkes ATPase. CLARE: ELSEVIER SCI IRELAND LTD.
Jones, C. E., Cobine, P. A., Daly, N. and Dameron, C. (2001). Structural studies of MNKr2-the second metal binding domain of the Menkes ATPase. Annual Meeting Society for Experimental Biology, Canterbury, UK, 2-6 April 2001. Canterbury, UK: University of Kent.
Bansal, P. S., Grieve, P. A., Marschke, R. J., Daly, N. L., Junius, K., Craik, D. J. and Alewood, P. F. (2001). Synthesis and structure elucidation of kappa-casein (45-87) - A two dimensional nuclear magnetic resonance study. Dairy Ingredient Science 2000 Conference, Melbourne, Australia, 28-30 June, 2000. Melbourne, Australia: Dairy Industry Association of Australia..
Bansal, P. S., Grieve, P. A., Marschke, R. J., Daly, N. L., Mcghie, E., Craik, D. J. and Alewood, P. F. (2000). Synthesis and structure elucidation of kappa-casein (1-44) - A two-dimensional nuclear magnetic resonance study. Dairy Ingredient Science 2000 Conference, Melbourne, Australia, 28-30 June, 2000. Melbourne, Australia: Dairy Industry Association of Australia.
Data Collection
Hardy, Margaret, Daly, Norelle L., Mobli, Mehdi , Morales, Rodrigo and King, Glenn F (2013). Isolation of an orally active insecticidal toxin from the venom of an Australian tarantula (Table S1). Figshare. (Dataset) doi: 10.1371/journal.pone.0073136.s001