Physiology of circadian rhythms

Our research addresses an issue of critical importance targeting the understanding of the consequence of circadian disruption on health and disease

The rotation of the Earth around its own axis creates daily changes in the environment of all living species.

To anticipate these changes and be more adapted to this fluctuating environment, they have all adapted an evolutionary conserved circadian clock that controls most aspects of physiology.

The exposition to conditions that disrupt this circadian clock such as shift work, disrupted light exposure or the use of screens or smartphones at night causes chronodisruption that can have a broad impact on health, including predispositions for pathologies like obesity, diabetes, cancer or neurological disorders.

Our goal is to understand and characterize the mechanisms of how chronodisruption can lead to the development of pathology. Our research addresses an issue of critical importance targeting the understanding of the consequence of circadian disruption on health and disease. Our understanding of the causal relationship between chronodisruption and pathologies will open new possibilities to fight these diseases and prevent their development through new health policies or pharmacological treatments.