Journal Articles
Pizzuto, Malvina, Monteleone, Mercedes, Burgener, Sabrina Sofia, Began, Jakub, Kurera, Melan, Chia, Jing Rong, Frampton, Emmanuelle, Crawford, Joanna, Oliveira, Monalisa, Kenney, Kirsten M., Coombs, Jared R., Yamamoto, Masahiro, Man, Si Ming, Broz, Petr, Pelegrin, Pablo and Schroder, Kate (2024). Cardiolipin Inhibits the Noncanonical Inflammasome by Preventing LPS Binding to Caspase 4/11 to Mitigate Endotoxemia in Vivo. BioRxiv. doi: 10.1101/2024.10.14.618051
Pizzuto, Malvina, Hurtado-Navarro, Laura, Molina-Lopez, Cristina, Soubhye, Jalal, Gelbcke, Michel, Rodriguez-Lopez, Silvia, Ruysschaert, Jean-Marie, Schroder, Kate and Pelegrin, Pablo (2024). Ornithine lipid is a partial TLR4 agonist and NLRP3 activator. Cell Reports, 43 (10) 114788, 1-24. doi: 10.1016/j.celrep.2024.114788
Chan, Amy H., Burgener, Sabrina S., Vezyrgiannis, Kassandra, Wang, Xiaohui, Acklam, Jadie, Von Pein, Jessica B., Pizzuto, Malvina, Labzin, Larisa I., Boucher, Dave and Schroder, Kate (2023). Caspase-4 dimerisation and D289 auto-processing elicit an
interleukin-1β-converting enzyme. Life Science Alliance, 6 (10) e202301908, 1-11. doi: 10.26508/lsa.202301908
Pizzuto, Malvina, Pelegrin, Pablo and Ruysschaert, Jean-Marie (2022). Lipid-protein interactions regulating the canonical and the non-canonical NLRP3 inflammasome. Progress in Lipid Research, 87 101182, 1-12. doi: 10.1016/j.plipres.2022.101182
Pizzuto, Malvina and Pelegrin, Pablo (2020). Cardiolipin in immune signaling and cell death. Trends in Cell Biology, 30 (11), 892-903. doi: 10.1016/j.tcb.2020.09.004
Siri, Macarena, Ruocco, Maria Julieta Fernandez, Achilli, Estefanía, Pizzuto, Malvina, Delgado, Juan F., Ruysschaert, Jean-Marie, Grasselli, Mariano and Alonso, Silvia Del V. (2019). Effect of structure in ionised albumin based nanoparticle: Characterisation, Emodin interaction, and in vitro cytotoxicity. Materials Science and Engineering C: Materials for Biological Applications, 103 109813, 109813. doi: 10.1016/j.msec.2019.109813
Pizzuto, Malvina, Lonez, Caroline, Baroja-Mazo, Alberto, Martínez-Banaclocha, Helios, Tourlomousis, Panagiotis, Gangloff, Monique, Pelegrin, Pablo, Ruysschaert, Jean-Marie, Gay, Nicholas J. and Bryant, Clare E. (2019). Saturation of acyl chains converts cardiolipin from an antagonist to an activator of Toll-like receptor-4. Cellular and Molecular Life Sciences, 76 (18), 3667-3678. doi: 10.1007/s00018-019-03113-5
Pizzuto, Malvina, Lonez, Caroline, Baroja-Mazo, Alberto, Martínez-Banaclocha, Helios, Tourlomousis, Panagiotis, Gangloff, Monique, Pelegrin, Pablo, Ruysschaert, Jean-Marie, Gay, Nicholas J and Bryant, Clare E (2019). Correction to: Saturation of acyl chains converts cardiolipin from an antagonist to an activator of Toll-like receptor-4. Cellular and Molecular Life Sciences, 76 (18), 3679-3680. doi: 10.1007/s00018-019-03229-8
Alarcón-Vila, Cristina, Pizzuto, Malvina and Pelegrín, Pablo (2019). Purinergic receptors and the inflammatory response mediated by lipids. Current Opinion in Pharmacology, 47, 90-96. doi: 10.1016/j.coph.2019.02.004
Pizzuto, Malvina, Bigey, Pascal, Lachagès, Anne-Marie, Hoffmann, Céline, Ruysschaert, Jean-Marie, Escriou, Virginie and Lonez, Caroline (2018). Cationic lipids as one-component vaccine adjuvants: a promising alternative to alum. Journal of Controlled Release, 287, 67-77. doi: 10.1016/j.jconrel.2018.08.020
Herrera, María Georgina, Pizzuto, Malvina, Lonez, Caroline, Rott, Karsten, Hütten, Andreas, Sewald, Norbert, Ruysschaert, Jean-Marie and Dodero, Veronica Isabel (2018). Large supramolecular structures of 33-mer gliadin peptide activate toll-like receptors in macrophages. Nanomedicine: Nanotechnology, Biology and Medicine, 14 (4), 1417-1427. doi: 10.1016/j.nano.2018.04.014
Pizzuto, Malvina, Gangloff, Monique, Scherman, Daniel, Gay, Nicholas J., Escriou, Virginie, Ruysschaert, Jean-Marie and Lonez, Caroline (2017). Toll-like receptor 2 promiscuity is responsible for the immunostimulatory activity of nucleic acid nanocarriers. Journal of Controlled Release, 247, 182-193. doi: 10.1016/j.jconrel.2016.12.029
Lonez, Caroline, Irvine, Kate L., Pizzuto, Malvina, Schmidt, Boris I., Gay, Nick J., Ruysschaert, Jean-Marie, Gangloff, Monique and Bryant, Clare E. (2015). Critical residues involved in Toll-like receptor 4 activation by cationic lipid nanocarriers are not located at the lipopolysaccharide-binding interface. Cellular and Molecular Life Sciences, 72 (20), 3971-3982. doi: 10.1007/s00018-015-1915-1
Conference Papers
Ruysschaert, Jean-Marie, Lonez, Caroline and Pizzuto, Malvina (2018). Cardiolipin Acts as an Agonist or an Antagonist of Toll Like Receptor (TLR4). 62nd Annual Meeting of the Biophysical-Society, San Francisco Ca, Feb 17-21, 2018. CAMBRIDGE: CELL PRESS.
Ruysschaert, Jean-Marie, Pizzuto, Malvina and Lonez, Caroline (2016). Non Bacterial Lipid and Proteins Aggregates are Activators of the Innate System. 60th Annual Meeting of the Biophysical-Society, Los Angeles Ca, Feb 27-Mar 02, 2016. CAMBRIDGE: CELL PRESS. doi: 10.1016/j.bpj.2015.11.3160
Lonez, Caroline, Irvine, Kate, Gangloff, Monique, Pizzuto, Malvina, Schmidt, Boris, Caroyez, Benjamin, Vandenbranden, Michel, Bryant, Clare and Ruysschaert, Jean-Marie (2014). Cationic Lipid and Bacterial Lipopolysaccharides Both Activate Toll-Like Receptor 4 Pathways via Different Binding Regions. 58th Annual Meeting of the Biophysical-Society, San Francisco Ca, Feb 15-19, 2014. CAMBRIDGE: CELL PRESS. doi: 10.1016/j.bpj.2013.11.1783