Dr Lin Luo
Research Officer
Institute for Molecular Bioscience
+61 7 334 62035
+61 7 334 62332
Researcher biography
Dr Lin Luo (PhD) is an early career researcher (ECR) at the IMB, UQ. He graduated with a PhD supervised by Prof Phil Robinson at Children's Medical Research Institute, Sydney University in late 2012. Since 2012 he has been appointed as a postdoctoral researcher in the laboratory of Prof Jenny Stow, IMB, The University of Queensland. His training has included acquiring advanced skills in a wide array of techniques, including structural biology, proteomics, and cell biology, and his research output is building a reputation in cell biology, immunology and inflammation.
Journal Articles
Teo, Wei Xuan, Yang, Zhe, Kerr, Markus Charles, Luo, Lin, Guo, Zhong, Alexandrov, Kirill, Stow, Jenny Lea and Teasdale, Rohan David (2017) Salmonella effector SopD2 interferes with Rab34 function. Cell Biology International, 41 4: 433-446. doi:10.1002/cbin.10739
Luo, Lin, Tong, Samuel J., Wall, Adam A., Khromykh, Tatiana, Sweet, Matthew J. and Stow, Jennifer L. (2017) Development of SH2 probes and pull-down assays to detect pathogen-induced, site-specific tyrosine phosphorylation of the TLR adaptor SCIMP. Immunology and Cell Biology, 95 6: 564-570. doi:10.1038/icb.2017.10
Wall, Adam A., Luo, Lin, Hung, Yu, Tong, Samuel J., Condon, Nicholas D., Blumenthal, Antje, Sweet, Matthew J. and Stow, Jennifer L. (2017) Small GTPase Rab8a-recruited phosphatidylinositol 3-kinase γ regulates signaling and cytokine outputs from endosomal toll-like receptors. Journal of Biological Chemistry, 292 11: 4411-4422. doi:10.1074/jbc.M116.766337
Luo, Lin, Bokil, Nilesh J., Wall, Adam A., Kapetanovic, Ronan, Lansdaal, Natalie M., Marceline, Faustine, Burgess, Belinda J., Tong, Samuel J., Guo, Zhong, Alexandrov, Kirill, Ross, Ian L., Hibbs, Margaret L., Stow, Jennifer L. and Sweet, Matthew J. (2017) SCIMP is a transmembrane non-TIR TLR adaptor that promotes proinflammatory cytokine production from macrophages. Nature Communications, 8 . doi:10.1038/ncomms14133
Yeo, Jeremy C., Wall, Adam A., Luo, Lin, Condon, Nicholas D. and Stow, Jennifer L. (2016) Distinct roles for APPL1 and APPL2 in regulating toll-like receptor 4 signaling in macrophages. Traffic, 17 9: 1014-1026. doi:10.1111/tra.12415
Luo, Lin, Xue, Jing, Kwan, Ann, Gamsjaeger, Roland, Wielens, Jerome, von Kleist, Lisa, Cubeddu, Liza, Guo, Zhong, Stow, Jennifer L., Parker, Michael W., Mackay, Joel P. and Robinson, Phillip J. (2016) The binding of syndapin SH3 domain to dynamin proline-rich domain involves short and long distance elements. Journal of Biological Chemistry, 291 18: 9411-+. doi:10.1074/jbc.M115.703108
Yeo, Jeremy C., Wall, Adam A., Luo, Lin and Stow, Jennifer L. (2016) Sequential recruitment of Rab GTPases during early stages of phagocytosis. Cellular Logistics, 6 1: e1140615.1-e1140615.12. doi:10.1080/21592799.2016.1140615
Yeo, Jeremy C., Wall, Adam A., Luo, Lin and Stow, Jennifer L. (2015) Rab31 and APPL2 enhance FcγR-mediated phagocytosis through PI3K/Akt signaling in macrophages. Molecular Biology of the Cell, 26 5: 952-965. doi:10.1091/mbc.E14-10-1457
King, Nathan P., Newton, Patrice, Schuelein, Ralf, Brown, Darren L., Petru, Marketa, Zarsky, Vojtech, Dolezal, Pavel, Luo, Lin, Bugarcic, Andrea, Stanley, Amanda C., Murray, Rachael Z., Collins, Brett M., Teasdale, Rohan D., Hartland, Elizabeth L. and Stow, Jennifer L. (2015) Soluble NSF attachment protein receptor molecular mimicry by a Legionella pneumophila Dot/Icm effector. Cellular Microbiology, 17 6: 767-784. doi:10.1111/cmi.12405
Luo, Lin, Wall, Adam A., Yeo, Jeremy C., Condon, Nicholas D., Norwood, Suzanne J., Schoenwaelder, Simone, Chen, Kaiwen W., Jackson, Shaun, Jenkins, Brendan J., Hartland, Elizabeth L., Schroder, Kate, Collins, Brett M., Sweet, Matthew J. and Stow, Jennifer L. (2014) Rab8a interacts directly with PI3Kγ to modulate TLR4-driven PI3K and mTOR signalling. Nature Communications, 5 4407.1-4407.13. doi:10.1038/ncomms5407
Luo, Lin, King, Nathan P., Yeo, Jeremy C., Jones, Alun and Stow, Jennifer L. (2013) Single-step protease cleavage elution for identification of protein-protein interactions from GST pull-down and mass spectrometry. Proteomics, Accepted Article 1-15. doi:10.1002/pmic.201300315
Rao, Yijian, Ma, Qingjun, Vahedi-Faridi, Ardeschir, Sundborger, Anna, Pechstein, Arndt, Puchkov, Dmytro, Luo, Lin, Shupliakov, Oleg, Saenger, Wolfram and Haucke, Volker (2010) Molecular basis for SH3 domain regulation of F-BAR-mediated membrane deformation. Proceedings of the National Academy of Sciences , 107 18: 8213-8218. doi:10.1073/pnas.1003478107
Luo, Lin, Tong, XingZhang and Farley, Peter C. (2007) The Candida albicans gene HGT12 (orf19.7094) encodes a hexose transporter. FEMS Immunology and Medical Microbiology, 51 1: 14-17. doi:10.1111/j.1574-695X.2007.00274.x
Conference Paper
Luo, L., Bokil, N., Lansdaal, N., Wall, A., Marceline, F., Guo, Z., Alexandrov, K., Ross, I, Hibbs, M., Stow, J. and Sweet, M. (2016). A new Toll-like receptor adaptor protein that provides specificity to inflammatory cytokine production from macrophages. In: European Journal of Immunology. International Congress of Immunology (ICI), Melbourne Australia, (86-87). Aug 21-26, 2016.